Endocannabinoids

The endocannabinoid system (ECS) is a group of endogenous cannabinoid receptors located in the mammalian brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors.

Known as "the body’s own cannabinoid system", the ECS is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory, and in mediating the psychoactive effects of cannabis. The ECS is also involved in voluntary exercise and may be related to the evolution of the runner's high in human beings and related aspects of motivation or reward for locomotor activity in other animals.

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