Current:

• Department of Veterans Affairs BLR&D VA Merit 1I01BX006849-01 (PI, Bandyopadhyay) Funding period: 04/01/2025 – 03/31/2029;  Title: Calcium signaling mechanism in proximal tubule underlying calcium nephrolithiasis.  Project Description: The major goal of this project is to find the mechanism of calcium stone formation and testing the intervention in animal model.

• Department of Veterans Affairs RR&D Merit 1 I21 RX004379-01A1 (PI, Bandyopadhyay) Funding period: 10/01/23 - 09/30/25;    Title: Alleviation of chronic TBI through modulation of calcium signaling.  Project Description: The major goal of this project is to identify the potential new therapeutic options for these TBI patients by restoring the upstream signaling connections, normalize GH levels, and improve the quality of life.

• Department of Veterans Affairs BLR&D Merit 1I21BX006418-01A1 (PI, Bandyopadhyay) Funding period: 10/01/2024 - 06/30/2027;  Title: Engineered 3D microfluidic tubular device as multimodal, functional tissue model.  Project Description: The major goal of this project is to evaluate/validate the microfluidic model to understand the contribution of dynamic microenvironmental cues (e.g., cellular regulations, microscale hydrodynamics) in calcium stone formation.

Completed:

• PA-18-586; funded by NIH/NIDDK. RESEARCH SUPPLEMENTS TO PROMOTE DIVERSITY IN HEALTH-RELATED RESEARCH. PI: Bandyopadhyay; Diversity candidate: Ms. Eugenia Awuah Boadi Funding period: 03/01/19 - 12/31/23; Title: Gender difference in Proximal Tubular mechanism for Calcium Phosphate stone formation. Project Description: This study investigate the gender difference in Ca2+ signaling in PT cells to understand calcium stones formation between genders.

• PA18-658; funded by the Office of Research on Women's Health (ORWH) through NIDDK.  PI: Bandyopadhyay  Funding period: 11/01/18 - 12/31/23; Title: Gender difference in stone-forming phenotype in mice. Project Description: This study will investigate in animal model to explore the mechanism of why younger females have a greater risk of CaP stone formation and provide evidence for the mechanism CaP stone formation in woman, as well as potential in vivo interventions.

•  PA13-302- RESEARCH PROJECT GRANT (PARENT R01),  PI: Bandyopadhyay Funding period: 11/01/15 - 12/31/23; Title: Calcium transport in kidney proximal tubule and calcium phosphate stone formation. Project Description: This study will investigate role of Ca2+-sensing receptor and TRPC3 channel in kidney stone formation.

• PA-13-303- NIH Exploratory/Developmental Research Grant Program (Parent R21), R21-EB021483-01A1 PI: Bandyopadhyay Funding period: 06/01/2017 - 11/31/2021. Title: Mechanism of calcium phosphate stone formation in engineered 3D tubule. Project Description: To create biologically active three-dimensional (3D) tubular tissues in microfluidics for exploring the mechanisms of biologically controlled calcium phosphate stone disease.  

• NIH GHUCCTS- TL1 Translational Biomedical Science Program. Mentor: Bandyopadhyay; Trainee: Pennington Funding period: 10/1/2017 - 9/30/2019   Title: Calcium signaling biomarkers in muscle disease. Project Description: The major goals of this project are to define the role of the Ca2+ channel in muscle disease to identify the signaling partners essential for the survival of skeletal muscle.

• NIH GHUCCTS-Pilot and Collaborative Studies Program RX-4004-079-HU-PCSP. PI: Bandyopadhyay Funding period: 7/14/2014 - 8/30/2017 Title: Role of TRPC1 in pulmonary epithelial ROS generation and COPD. Project Description: The major goals of this project are to define the role of the Ca2+ influx channel, TRPC1, in oxidative stress and COPD to identify the signaling partners essential for the survival of pulmonary epithelia.

• NIH Small grant program 1R03DE019524-01A1. PI: Bandyopadhyay Funding period: 05/01/10 - 04/30/13. Title: Function of TRPC3 channel in salivary gland. Project description: This study looked at the role of Ca2+-sensing receptor and TRPC3 channel in regulating Ca2+ transport.   

• National Kidney Foundation (NKF) Research Investigator program. PI: Bandyopadhyay  Funding period: 07/01/10 – 06/30/14 Title: Function of TRPC3 in Kidney Proximal Tubule, Project description: This study investigated the regulation of Ca2+ entry through TRPC3 channel in kidney proximal tubule.

• NIH, NCRR (COBRE) P20 RR017699. Co-I: Bandyopadhyay (Project leader Brij B Singh). Project title: TRPC1, Calcium, and Parkinson’s disease. Project description: The long-term goal of this project is to elucidate the role and the mechanism of TRPC1 channels in Parkinson’s disease.