C-Neurophysiology Lab

Publication

You can see the full list in PubMed as here: Link

Recent 5 years (2020 ~ present)

Phospholipase A2 downregulates inhibitory transmission in the amygdala and impairs fear extinction.

Park K, Chung C#.

Neuropsychopharmacology. 2026 Jun 15.

FKBP5 deficiency selectively impairs NMDAR-dependent long-term depression via enhanced calcineurin activity: Implications for stress resilience.

Zhang S, Jeon YJ, Han JS, Park H, Chung C#.

Prog Neurobiol. 2025 Aug;251:102801. doi: 10.1016/j.pneurobio.2025.102801.

Regulation of sociability by the cortico-habenula pathway in an animal model of depression.

Park H, Chung C#.

Prog Neurobiol. 2025 Aug;251:102799. doi: 10.1016/j.pneurobio.2025.102799.

Egr2 Modulation in the Medial Prefrontal Cortex Regulates Resistance to Stress-Induced Memory Impairments.

Park JC*, Ryu H*, Kim NH, Jeon YJ, Kang HJ, Choi JS, Chung C#, Han JS#.

Eur Neuropsychopharmacol. 2025 Jul;96:9-11. doi: 10.1016/j.euroneuro.2025.03.010.

Early postnatal exposure to bicuculline modulates E/I balance and induces ASD-like behavioral phenotypes in mice.

Shin D, Cho E, Park K, Chung C, Kim DH, Jeon SJ, Shin CY.

Anim Cells Syst (Seoul). 2025 Apr 28;29(1):264-281.

Distinct Impact of Inflammatory Versus Psychophysiological Stress on Brain-Wide Activation of Melanocortin Receptor 4-Expressing Neurons.

Cheon M, Kim W, Chung C#.

FASEB J. 2025 Apr 15;39(7):e70527. doi: 10.1096/fj.202403158R.

Mitogen-activated protein kinase dependent presynaptic potentiation in the lateral habenula mediates depressive-like behaviors in rats.

Park H, Ryu H, Zhang S, Kim S, Chung C#.

Neuropsychopharmacology. 2025 Feb;50(3):540-547. doi: 10.1038/s41386-024-02025-8.

Effect of dynamic interaction of estrous cycle and stress on synaptic transmission and neuronal excitability in the lateral habenula.

Kim W, Chung C#.

FASEB J. 2024 Dec 15;38(24):e70275.

Mu-opioid receptor activation in the habenula modulates synaptic transmission and depression-like behaviors.

Park H, Ryu H, Zhang S, Rhee J, Chung C#.

Neurobiol Dis. 2024 Aug;198:106543. doi: 10.1016/j.nbd.2024.106543.

Fear conditioning and extinction distinctively alter bidirectional synaptic plasticity within the amygdala of an animal model of post-traumatic stress disorder.

Park K, Park H, Chung C#.

Neurobiol Stress. 2024 Jan 12;29:100606. doi: 10.1016/j.ynstr.2024.100606.

Non-Targeted Metabolomics Investigation of a Sub-Chronic Variable Stress Model Unveils Sex-Dependent Metabolic Differences Induced by Stress.

Kang S, Kim W, Nam J, Li K, Kang Y, Bae B, Chun KH, Chung C, Lee J.

Int J Mol Sci. 2024 Feb 19;25(4):2443. doi: 10.3390/ijms25042443.

Stress-induced translation of KCNB1 contributes to the enhanced synaptic transmission of the lateral habenula.

Ryu H, Kim M, Park H, Choi HK, Chung C#.

Front Cell Neurosci. 2023 Dec 13;17:1278847. doi: 10.3389/fncel.2023.1278847.

The neural basis underlying female vulnerability to depressive disorders.

Kim M, Kim W, Chung C#.

Anim Cells Syst (Seoul). 2023 Nov 10;27(1):297-308. doi: 10.1080/19768354.2023.2276815.

Mitochondria-derived peptide SHLP2 regulates energy homeostasis through the activation of hypothalamic neurons.

Kim SK, Tran LT, NamKoong C, Choi HJ, Chun HJ, Lee YH, Cheon M, Chung C, Hwang J, Lim HH, Shin DM, Choi YH, Kim KW.

Nat Commun. 2023 Jul 19;14(1):4321. doi: 10.1038/s41467-023-40082-7.

Lateral Septum Somatostatin Neurons are Activated by Diverse Stressors.

An M, Kim HK, Park H, Kim K, Heo G, Park HE, Chung C#, Kim SY#.

Exp Neurobiol. 2022 Dec 31;31(6):376-389. doi: 10.5607/en22024.

Interaction Between Glucocorticoid Receptors and FKBP5 in Regulating Neurotransmission of the Hippocampus.

Zhang S*, Cheon M*, Park H, Kim T, Chung C.

Neuroscience. 2022 Feb 10;483:95-103. doi: 10.1016/j.neuroscience.2021.12.020.

Maternal exposure to polystyrene nanoplastics causes brain abnormalities in progeny.

Jeong B, Baek JY, Koo J, Park S, Ryu YK, Kim KS, Zhang S, Chung C, Dogan R, Choi HS, Um D, Kim TK, Lee WS, Jeong J, Shin WH, Lee JR, Kim NS, Lee DY.

J Hazard Mater. 2022 Mar 15;426:127815. doi: 10.1016/j.jhazmat.2021.127815.

Brain-wide cellular mapping of acute stress-induced activation in male and female mice.

Kim W, Chung C.

FASEB J. 2021 Dec;35(12):e22041. doi: 10.1096/fj.202101287R.

Left-right asymmetric and smaller right habenula volume in major depressive disorder on high-resolution 7-T magnetic resonance imaging.

Cho SE, Park CA, Na KS, Chung C, Ma HJ, Kang CK, Kang SG.

PLoS One. 2021 Aug 3;16(8):e0255459. doi: 10.1371/journal.pone.0255459.

REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse.

Kim SM, Zhang S, Park J, Sung HJ, Tran TT, Chung C, Han IO.

Neurotherapeutics. 2021 Oct;18(4):2504-2517. doi: 10.1007/s13311-021-01094-7.

The Impact of FKBP5 Deficiency in Glucocorticoid Receptor Mediated Regulation of Synaptic Transmission in the Medial Prefrontal Cortex.

Ryu H*, Cheon M*, Chung C.

Neuroscience. 2021 Mar 1;457:20-26. doi: 10.1016/j.neuroscience.2020.12.020.

Protein kinase C mediates neuropeptide Y-induced reduction in inhibitory neurotransmission in the lateral habenula.

Cheon M*, Park H*, Chung C.

Neuropharmacology. 2020 Dec 1;180:108295. doi: 10.1016/j.neuropharm.2020.108295.

Inositol hexakisphosphate kinase-1 is a key mediator of prepulse inhibition and short-term fear memory.

Kim MG*, Zhang S*, Park H, Park SJ, Kim S#, Chung C#.

Mol Brain. 2020 May 7;13(1):72. doi: 10.1186/s13041-020-00615-3.

Elevated O-GlcNAcylation induces an antidepressant-like phenotype and decreased inhibitory transmission in the medial prefrontal cortex.

Cho Y, Hwang H, Rahman MA, Chung C#, Rhim H#.

Sci Rep. 2020 Apr 24;10(1):6924. doi: 10.1038/s41598-020-63819-6.

Inositol Pyrophosphate Metabolism Regulates Presynaptic Vesicle Cycling at Central Synapses.

Park SJ*, Park H*, Kim MG*, Zhang S, Park SE, Kim S#, Chung C#.

iScience. 2020 Apr 24;23(4):101000. doi: 10.1016/j.isci.2020.101000.

Differential Alterations in Cortico-Amygdala Circuitry in Mice with Impaired Fear Extinction.

Park K, Chung C.

Mol Neurobiol. 2020 Feb;57(2):710-721. doi: 10.1007/s12035-019-01741-3.

Before 2020-

Gene-environment interaction counterbalances social impairment in mouse models of autism.

Kim JW, Park K, Kang RJ, Gonzales EL, Oh HA, Seung H, Ko MJ, Cheong JH, Chung C, Shin CY.

Sci Rep. 2019 Aug 7;9(1):11490. doi: 10.1038/s41598-019-47680-w.

Actions of Neuropeptide Y on Synaptic Transmission in the Lateral Habenula.

Cheon M*, Park H*, Rhim H, Chung C.

Neuroscience. 2019 Jul 1;410:183-190. doi: 10.1016/j.neuroscience.2019.04.053.

Fusion of Reprogramming Factors Alters the Trajectory of Somatic Lineage Conversion.

Velychko S, Kang K, Kim SM, Kwak TH, Kim KP, Park C, Hong K, Chung C, Hyun JK, MacCarthy CM, Wu G, Schöler HR, Han DW.

Cell Rep. 2019 Apr 2;27(1):30-39.e4. doi: 10.1016/j.celrep.2019.03.023.

Systemic Cellular Activation Mapping of an Extinction-Impaired Animal Model.

Park K, Chung C.

Front Cell Neurosci. 2019 Mar 19;13:99. doi: 10.3389/fncel.2019.00099.

Pharmacological modulation of AMPA receptor rescues social impairments in animal models of autism.

Kim JW*, Park K*, Kang RJ, Gonzales ELT, Kim DG, Oh HA, Seung H, Ko MJ, Kwon KJ, Kim KC, Lee SH, Chung C, Shin CY.

Neuropsychopharmacology. 2019 Jan;44(2):314-323. doi: 10.1038/s41386-018-0098-5.

Impaired Hippocampal Synaptic Plasticity and Enhanced Excitatory Transmission in a Novel Animal Model of Autism Spectrum Disorders with Telomerase Reverse Transcriptase Overexpression.

Rhee J#, Park K#, Kim KC, Shin CY, Chung C.

Mol Cells. 2018 May 31;41(5):486-494. doi: 10.14348/molcells.2018.0145.

Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception.

Sung K, Ferrari LF, Yang W, Chung C, Zhao X, Gu Y, Lin S, Zhang K, Cui B, Pearn ML, Maloney MT, Mobley WC, Levine JD, Wu C.

J Neurosci. 2018 Apr 4;38(14):3394-3413. doi: 10.1523/JNEUROSCI.1686-17.2018.

Selectively Impaired Endocannabinoid-Dependent Long-Term Depression in the Lateral Habenula in an Animal Model of Depression.

Park H, Rhee J, Lee S, Chung C.

Cell Rep. 2017 Jul 11;20(2):289-296. doi: 10.1016/j.celrep.2017.06.049.

Exposure to Stressors Facilitates Long-Term Synaptic Potentiation in the Lateral Habenula.

Park H, Rhee J, Park K, Han JS, Malinow R, Chung C.

J Neurosci. 2017 Jun 21;37(25):6021-6030. doi: 10.1523/JNEUROSCI.2281-16.2017.

Temporal variations in presynaptic release probability in the lateral habenula.

Park H, Cheon M, Kim S, Chung C.

Sci Rep. 2017 Jan 20;7:40866. doi: 10.1038/srep40866.

nArgBP2 regulates excitatory synapse formation by controlling dendritic spine morphology.

Lee SE, Kim Y, Han JK, Park H, Lee U, Na M, Jeong S, Chung C, Cestra G, Chang S.

Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):6749-54. doi: 10.1073/pnas.1600944113.

Hippocampus-dependent cognitive enhancement induced by systemic gintonin administration.

Kim S#, Kim MS#, Park K, Kim HJ, Jung SW, Nah SY, Han JS, Chung C.

J Ginseng Res. 2016 Jan;40(1):55-61. doi: 10.1016/j.jgr.2015.05.001.

Overexpression of Telomerase Reverse Transcriptase Induces Autism-like Excitatory Phenotypes in Mice.

Kim KC, Rhee J, Park JE, Lee DK, Choi CS, Kim JW, Lee HW, Song MR, Yoo HJ, Chung C, Shin CY.

Mol Neurobiol. 2016 Dec;53(10):7312-7328. doi: 10.1007/s12035-015-9630-3.

Oxytocin Protects Hippocampal Memory and Plasticity from Uncontrollable Stress.

Lee SY, Park SH, Chung C, Kim JJ, Choi SY, Han JS.

Sci Rep. 2015 Dec 21;5:18540. doi: 10.1038/srep18540.

Decreased Na(+) influx lowers hippocampal neuronal excitability in a mouse model of neonatal influenza infection.

Park H, Yu JE, Kim S, Nahm SS, Chung C.

Sci Rep. 2015 Aug 27;5:13440. doi: 10.1038/srep13440.

Oral Administration of Gintonin Attenuates Cholinergic Impairments by Scopolamine, Amyloid-β Protein, and Mouse Model of Alzheimer's Disease.

Kim HJ, Shin EJ, Lee BH, Choi SH, Jung SW, Cho IH, Hwang SH, Kim JY, Han JS, Chung C, Jang CG, Rhim H, Kim HC, Nah SY.

Mol Cells. 2015 Sep;38(9):796-805. doi: 10.14348/molcells.2015.0116.

Synaptic enhancement induced by gintonin via lysophosphatidic acid receptor activation in central synapses.

Park H, Kim S, Rhee J, Kim HJ, Han JS, Nah SY, Chung C.

J Neurophysiol. 2015 Mar 1;113(5):1493-500. doi: 10.1152/jn.00667.2014.

Learning strategy preference of 5XFAD transgenic mice depends on the sequence of place/spatial and cued training in the water maze task.

Cho WH, Park JC, Chung C, Jeon WK, Han JS.

Behav Brain Res. 2014 Oct 15;273:116-22. doi: 10.1016/j.bbr.2014.07.033.

Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus.

Ma J, Choi BR, Chung C, Min SS, Jeon WK, Han JS.

Mol Brain. 2014 Apr 24;7:33. doi: 10.1186/1756-6606-7-33.

Increased expression of the receptor for advanced glycation end products in neurons and astrocytes in a triple transgenic mouse model of Alzheimer's disease.

Choi BR, Cho WH, Kim J, Lee HJ, Chung C, Jeon WK, Han JS.

Exp Mol Med. 2014 Feb 7;46(2):e75. doi: 10.1038/emm.2013.147.

Activation of lysophosphatidic acid receptor by gintonin inhibits Kv1.2 channel activity: involvement of tyrosine kinase and receptor protein tyrosine phosphatase α.

Lee JH, Choi SH, Lee BH, Hwang SH, Kim HJ, Rhee J, Chung C, Nah SY.

Neurosci Lett. 2013 Aug 26;548:143-8. doi: 10.1016/j.neulet.2013.05.048.

NMDA receptor as a newly identified member of the metabotropic glutamate receptor family: clinical implications for neurodegenerative diseases.

Chung C.

Mol Cells. 2013 Aug;36(2):99-104. doi: 10.1007/s10059-013-0113-y.

Vesicle dynamics: how synaptic proteins regulate different modes of neurotransmission.

Chung C, Raingo J.

J Neurochem. 2013 Jul;126(2):146-54. doi: 10.1111/jnc.12245.

Multiple biological properties of macelignan and its pharmacological implications.

Paul S, Hwang JK, Kim HY, Jeon WK, Chung C, Han JS.

Arch Pharm Res. 2013 Mar;36(3):264-72. doi: 10.1007/s12272-013-0048-z.

New perspectives on glutamate receptor antagonists as antidepressants.

Chung C.

Arch Pharm Res. 2012 Mar;35(4):573-7. doi: 10.1007/s12272-012-0400-8.

Long-term synaptic plasticity in deep layer-originated associational projections to superficial layers of rat entorhinal cortex.

Yang S, Lee DS, Chung CH, Cheong MY, Lee CJ, Jung MW.

Neuroscience. 2004;127(4):805-12. doi: 10.1016/j.neuroscience.2004.06.001.

During my training in the USA

Spontaneous neurotransmission: an independent pathway for neuronal signaling?

Kavalali ET, Chung C, Khvotchev M, Leitz J, Nosyreva E, Raingo J, Ramirez DM.

Physiology (Bethesda). 2011 Feb;26(1):45-53. doi: 10.1152/physiol.00040.2010.

Synaptic potentiation onto habenula neurons in the learned helplessness model of depression.

Li B*, Piriz J*, Mirrione M*, Chung C*, Proulx CD, Schulz D, Henn F, Malinow R.

Nature. 2011 Feb 24;470(7335):535-9. doi: 10.1038/nature09742.

Synaptic vesicle endocytosis: get two for the price of one?

Chung C, Kavalali ET.

Neuron. 2009 Feb 12;61(3):333-4. doi: 10.1016/j.neuron.2009.01.022.

Spontaneous and evoked glutamate release activates two populations of NMDA receptors with limited overlap.

Atasoy D, Ertunc M, Moulder KL, Blackwell J, Chung C, Su J, Kavalali ET.

J Neurosci. 2008 Oct 1;28(40):10151-66. doi: 10.1523/JNEUROSCI.2432-08.2008.

Molecular substrates mediating lanthanide-evoked neurotransmitter release in central synapses.

Chung C, Deák F, Kavalali ET.

J Neurophysiol. 2008 Oct;100(4):2089-100. doi: 10.1152/jn.90404.2008. Epub 2008 Aug 20.

Fast synaptic vesicle reuse slows the rate of synaptic depression in the CA1 region of hippocampus.

Ertunc M, Sara Y, Chung C, Atasoy D, Virmani T, Kavalali ET.

J Neurosci. 2007 Jan 10;27(2):341-54. doi: 10.1523/JNEUROSCI.4051-06.2007.

Seeking a function for spontaneous neurotransmission.

Chung C, Kavalali ET.

Nat Neurosci. 2006 Aug;9(8):989-90. doi: 10.1038/nn0806-989.

Page updated

Google Sites

Report abuse