Exploring the Binding Kinetics of Chemotherapeutic Mitoxantrone to DNA using Optical Tweezers #22

Aaron J. Ferreira, Helena K. Beeloo, Thayaparan Paramanathan

68th Annual Meeting of the Biophysical Society @ Philadelphia, PA (Feb 10-14, 2024)

Optical Tweezers Reveal Nanomolar DNA Binding Affinity of Doxorubicin #21

Jacob McNally, Youri K. Nabhan, Irbazhusain Shaikh, Thayaparan Paramanathan

68th Annual Meeting of the Biophysical Society @ Philadelphia, PA (Feb 10-14, 2024)

Optical Tweezers Reveal Nanomolar DNA Binding Affinity of Doxorubicin #20

Jason Martin, Zachary Ells, Brian Dolle, Ioulia F. Rouzina, Mark C. Williams, Thayaparan Paramanathan

68th Annual Meeting of the Biophysical Society @ Philadelphia, PA (Feb 10-14, 2024) 

Remdesivir Displays Weak Binding to DNA in Optical Tweezers Experiments #19

Ryan Bauer, Thayaparan Paramanathan

67th Annual Meeting of the Biophysical Society @ San Diego, CA (Feb 18-22, 2023) 

Optical Tweezers Experiments Show Melting the DNA Facilitates the Binding of Minor Groove Binder Netropsin #18

Irbazhusain Shaikh, Thayaparan Paramanathan

67th Annual Meeting of the Biophysical Society @ San Diego, CA (Feb 18-22, 2023) 

Exploring the Binding of Mitoxantrone to DNA Using Optical Tweezers #17

Karan Patel, Thayaparan Paramanathan

67th Annual Meeting of the Biophysical Society @ San Diego, CA (Feb 18-22, 2023) 

Optical Tweezers Reveals Anticancer Drug BI-3802 Binds DNA in the  Micromolar Range #16

Jared McAuliffe, Mark C. Williams, Thayaparan Paramanathan

67th Annual Meeting of the Biophysical Society @ San Diego, CA (Feb 18-22, 2023) 

Exploring the Binding of Anticancer Drug BI-3802 to DNA Using Optical Tweezers #15

Jared McAuliffe, Thayaparan Paramanathan

66th Annual Meeting of the Biophysical Society @ San Francisco, CA (Feb 19-23, 2022) 

Characterizing DNA Polymerase Kappa's Binding Mechanism to DNA Using Optical Tweezers #14

Joshua Watts, Mark C. Williams, Samer Lone, Thayaparan Paramanathan

66th Annual Meeting of the Biophysical Society @ San Francisco, CA (Feb 19-23, 2022) 

Exploring the Doxorubicin-DNA Interactions by DNA Stretching Using Optical Tweezers #13

Zachary Ells, Brian Dolle,  Ioulia F Rouzina, Mark C. Williams, Thayaparan Paramanathan

65th Annual Meeting of the Biophysical Society @ Boston, MA - Held virtually due to the Pandemic (Feb 22-26, 2021) 

Probing the Binding Mechanism of DNA Polymerase Kappa to DNA using Optical Tweezers #12

Joshua Watts, Samer Lone,Thayaparan Paramanathan

64th Annual Meeting of the Biophysical Society @ San Diego, CA (Feb 15-19, 2020) 

Single-Molecule Studies of Doxorubicin-DNA Interactions Using Optical Tweezers #11

Zachary Ells, Brian Dolle, Mark C. Williams, Thayaparan Paramanathan

64th Annual Meeting of the Biophysical Society @ San Diego, CA (Feb 15-19, 2020) 

Effect of  Chirality on the Elastic Properties of DNA-Threading Binuclear Ruthenium Complex #10

Adam A Jabak, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley, Ioulia F Rouzina, Mark C Williams, Thayaparan Paramanathan

64th Annual Meeting of the Biophysical Society @ San Diego, CA (Feb 15-19, 2020) 

Quantifying Anticancer Drug Doxorubicin Binding to DNA using Optical Tweezers #9

Zachary Ells, Brian Dolle, Thayaparan Paramanathan

63rd Annual Meeting of the Biophysical Society @ Baltimore, MD (March 2-6, 2019) 

Investigating How Chirality of a Threading Binuclear Ruthenium Complex Affects the DNA Threading Intercalation using Optical Tweezers #8

Adam A Jabak, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley, Ioulia F Rouzina, Mark C Williams, Thayaparan Paramanathan

63rd Annual Meeting of the Biophysical Society @ Baltimore, MD (March 2-6, 2019)  

Investigating How Chirality of a Threading Binuclear Ruthenium Complex Affects the DNA Threading Intercalation using Optical Tweezers #7

Adam A Jabak, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley, Ioulia F Rouzina, Mark C Williams, Thayaparan Paramanathan

62nd Annual Meeting of the Biophysical Society @ San Francisco, CA (Feb 17-21, 2018)  

Role of Threading Moiety Size and Chirality in Determining the DNA Binding Characteristics of Threading Intercalators #6

Thayaparan Paramanathan, Andrew Clark, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley, Ioulia Rouzina, Mark C Williams 

61st Annual Meeting of the Biophysical Society @ New Orleans, LA (Feb 11-15, 2017)

Role of the Moiety Chirality in Determining the DNA Binding Characteristics of Threading Intercalators #5

Thayaparan Paramanathan, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah McCauley, Ioulia Rouzina, Mark C Williams

60th Annual Meeting of the Biophysical Society @ Los Angeles, CA (Feb 27 - Mar 2, 2016)

Constructing Dual Beam Optical Tweezers for Undergraduate Biophysics Research #4

Brian Daudelin, Devon West-Coates, Jon Del'Etoile, Eric Grotzke, Thayaparan Paramanathan

American Physical Society March Meeting @ Baltimore, MD (March 14-18, 2016)

Quantifying the DNA binding characteristics of ruthenium based threading intercalator Λ Λ -P with optical tweezers #3

Nicholas Bryden, Micah McCauley, Fredrik Westerlund, Per Lincoln, Ioulia Rouzina, Mark Williams, Thayaparan Paramanathan

American Physical Society March Meeting @ Baltimore, MD (March 14-18, 2016)

Threading Moieties Play a Significant Role in Determining the DNA Binding Properties of Binuclear Ruthenium Complexes #2

Thayaparan Paramanathan, Andrew Clark, Fredrick Westerlund, Per Lincoln, Micah J McCauley, Ioulia Rouzina, Mark C Williams

American Physical Society March Meeting @ San Antonio, TX (March 2-6, 2015)

Competitor Effect on Molecular Complex Dissociation in the Absence of Ternary Complex Formation #1

Thayaparan Paramanathan, Daniel Reeves, Larry Friedman, Jane Kondev, Jeff Gelles

59th Annual Meeting of the Biophysical Society @ Baltimore, MD (Feb 7-11, 2015)

Bold font indicates the Lead Presenters and Underlined Authors are Undergraduate Researchers