Choi TY, Jeon H, Jeong S, Kim EJ, Kim J, Jeong YH, Kang B, Choi M, Koo JW (2023) Distinct prefrontal projection activity and transcriptional state conversely orchestrate social competition and hierarchy. Neuron S0896-6273(23)00886-3. doi:10.1016/j.neuron.2023.11.012. 5 Dec 2023 published.
Choi M, Jang H-S, Son T, Kim D, Youn Y-J, Hwang G-B, Choi YP, Jeong YH (2023) Effect Sizes of Cognitive and Locomotive Behavior Tests in the 5XFAD-J Mouse Model of Alzheimer’s Disease. Int. J. Mol. Sci. 24(20), 15064; https://doi.org/10.3390/ijms242015064 11 Oct 2023 published
Choi M, Ryu J, Vu HD, Kim D, Youn Y-J, Park MH, Huynh PT, Hwang G-B, Youn SW, Jeong YH (2023) Transferrin-Conjugated Melittin-Loaded L-Arginine-Coated Iron Oxide Nanoparticles for Mitigating Beta-Amyloid Pathology of the 5XFAD Mouse Brain. Int. J. Mol. Sci. 24(19), 14954; https://doi.org/10.3390/ijms241914954 06 Oct 2023 published
Choi M, Kim D, Youn Y-J, Ryu J, Jeong YH (2022) Effect of Obesity and High-Density Lipoprotein Concentration on the Pathological Characteristics of Alzheimer’s Disease in High-Fat Diet-Fed Mice. Int. J. Mol. Sci. 23(20), 12296; https://doi.org/10.3390/ijms232012296 14 Oct 2022 published
Min S, Jeong YH, Kim J, Koo JW, Ahn YM (2021) The Aftermath: Post-pandemic Psychiatric Implications of the COVID-19 Pandemic, a South Korean Perspective. Font. Psychiatry ; doi: 10.3389/fpsyt.2021.671722, 21 Oct 2021 published
Choi M, Lee S-M, Kim D, Im H-I, Kim H-S, Jeong YH (2021) Disruption of the astrocyte–neuron interaction is responsible for the impairments in learning and memory in 5XFAD mice: an Alzheimer’s disease animal model. Mol Brain 14, 111; doi: 10.1186/s13041-021-00823-5
Park H, Han K-M, Jeon H, Lee J-S, Lee H, Jeon SG, Park J-H, Kim YG, Lin Y, Lee Y-H, Jeong YH* and Hoe H-S* (2020) The MAO Inhibitor Tranylcypromine Alters LPS and Aβ-Mediated Neuroinflammatory Responses in Wild-type Mice and a Mouse Model of AD. Cells 9(9), 1982; doi:10.3390/cells9091982 *Co-Corresponding
Lee JH, Ribeiro EA, Kim J, Ko B, Kronman H, Jeong YH, Kim JK, Janak PH, Nestler EJ, Koo JW, Kim JH (2020) Dopaminergic Regulation of Nucleus Accumbens Cholinergic Interneurons Demarcates Susceptibility to Cocaine Addiction. Biol Psychiatry 88(10):746-757
Donde A*, Sun M*, Jeong YH*, Ling J, Lin S, Braunstein K, Wang S, Chen L and Wong PC (2019) Upregulation of Atg7 attenuates motor neuron dysfunction associated with depletion of TDP-43. Autophagy 16(4):672-682 *Co-First
Labonté B*, Jeong YH*, Parise E, Issler O, Fatma M, Engmann O, Cho K, Neve Rachael, Nestler EJ, Koo JW (2019) Gadd45b mediates depressive-like role through DNA demethylation. Sci Rep. 9(1):4615 *Co-First
Jeong YH*, Ling J*, Lin S*, Donde A, Braunstein KE, Majounie E, Traynor BJ, LaClair K, Lloyd TE and Wong PC (2017) Tdp-43 cryptic exons are highly variable between cell types. Molecular Neurodegeneration 12:13 *Co-First
LaClair KD, Donde A, Ling JP, Jeong YH, Chhabra R, Martin LJ, Wong PC (2016) Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathologica 132(6), 859-873
Shin KY, Noh SJ, Park CH, Jeong YH, Chang KA, Yoo J, Kim HJ, Ha S, Kim HS, Park HJ, Lee JH, Moon C, Suh YH (2016) Dehydroevodiamine HCl protects against memory impairment and cerebral amyloid-β production in Tg2576 mice by acting as a β-secretase inhibitor. CNS Neurol Disord Drug Targets 15(8), 935-944
Haidet-Phillips AM, Gross SK, Williams T, Tuteja A, Sherman A, Ko M, Jeong YH, Wong PC, Maragakis NJ (2013) Altered astrocytic expression of TDP-43 does not influence motor neuron survival. Exp Neurol. 250, 250-259
Tsao W, Jeong YH, Lin S, Ling J, Price DL, Chiang PM, Wong PC (2012) Rodent Models of TDP-43: Recent advances. Brain Research 26(1462), 26-39
Jeong YH, Kim JM, Yoo J, Lee SH, Kim HS, Suh YH (2011) Environmental enrichment compensates for the effects of stress on disease progression in Tg2576 mice, an Alzheimer’s disease model. J Neurochem 119(6), 1282-1293
Chiang PM, Ling J, Jeong YH, Price DL, Aja SM, Wong PC (2010) Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proc Natl Acad Sci U S A 107(37), 16320-16324
Choi Y, Kim HS, Kim EM , Kim HS , Park CH , Shin KY, Jeong YH, Yoo J, Lee JP , Chang KA, Kim SH , Kim M, Suh YH (2007) Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's Disease Models. Neuropsychopharmacology 32(11), 2393-2404
Chang KA, Kim HS, Ha TY, Ha JW, Shin KY, Jeong YH, Lee JP, Park CH, Kim S, Baik TK, Suh YH (2006) Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration. Mol Cell Biol 26(11), 4327-4338
Jeong YH, Park CH, Yoo J, Shin KY, Ahn SM, Kim HS, Lee SH, Emson PC, Suh YH (2006) Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model. FASEB J 20(6), 729-731
General Researcher Program (Young Researchers), Principal Investigator
Sponsor: National Research Funding of Korea
Title: “Study on molecular connectome difference of stress susceptible and stress resilient in various models of depressive mood disorders”
Total costs: 500,000,000
Inclusive dates: 3/1/2019 – 2/29/2024
General Researcher Program (Young Researchers), Principal Investigator
Sponsor: National Research Funding of Korea
Title: “Elucidation of the role of TDP-43, an ALS/FTD linked protein, in eating disorder (anorexia nervosa, bulimia nervosa) and obesity”
Total costs: 150,000,000
Inclusive dates: 7/1/2014 – 6/30/2017