Borrelia burgdorferi is a pathogenic parasite that causes Lyme Disease
Lyme disease is in the stages: early localized disease, early disseminated disease, and late disease.
Post-treatment Lyme disease syndrome may occur where the symptoms are still there but the infection is gone
A spirochete injects itself, moves through connective tissues, and spreads infecting peripheral sites such as the heart, joints, and neural tissue. They also invade the immune system and persist in tissue.
The parasite invades immune systems in various ways such as attaching to immunosuppressive tick salivary glands and then spreading throughout the system.
Those that are frequently bitten by ticks have been shown to have immunity against tick salivary antigens leading them to be resistant to infection
Prepatent period: IgG tests for B.burgdorferi initially become positive in the first 4 to 6 weeks after infection and reach their peak around 3 months post-infection and may be around for years
Borrelia burgdoferi bacterium, CDC