Recent Cancer Research

Human cancers medical researchers have proven xanthones, from the outside pericarp of mangosteen, will kill (apoptosis), stop/reduce tumors, stop migration (metastasize) etc. Recommendations for whole fruit mangosteen product at very bottom of article.

1. 1. •  Anti-glioma properties of β-mangostin ability to foster an immunosuppressive microenvironment that inhibits glioma growth https://www.sciencedirect.com/science/article/pii/S0753332224009582 . 

      •  Exhibit cytotoxicity against human cancer cell lines including lung adenocarcinoma, cervical carcinoma, prostatic carcinoma, pancreatic carcinoma, hepatocellular carcinoma, bladder urothelial cancer, & triple-negative breast cancer cells https://www.sciencedirect.com/science/article/pii/S0753332224012502

      • Xanthone GarcinonE anti cancer "significantly abolished,..strongly inhibited tumor growth & reduced tumor weight..was the most potent dual inhibitor. https://www.sciencedirect.com/science/article/abs/pii/S0944711323004993 . 

      • Mangosteen Inhibits Growth & Survival of Cervical Cancer Cells https://pubmed.ncbi.nlm.nih.gov/35641300/

      • Mangosteen for malignancy prevention & intervention https://www.sciencedirect.com/science/article/pii/S104366182200576X

6.  Anti-angiogenic actions of the mangosteen polyphenolic xanthone  https://pubmed.ncbi.nlm.nih.gov/24721607/  

Tumor angiogenesis is the formation of new, abnormal, blood vessels. Tumors emit signals to create new blood vessels & orient them to the tumor, to nourish it. Mangosteen works ANTI the process.. 

1. 1. •  Potent Anti-Cancer Properties extensive analysis of in vitro and in vivo studies https://pubmed.ncbi.nlm.nih.gov/39595559/

      •  Hepatocellular (liver), Breast & Colon rectal Cancer: mangostana fruit hulls..a natural cytotoxic agent against various cancers..the scientific rationale of using G. mangostana in anti-cancer treatment.  https://www.ncbi.nlm.nih.gov/pubmed/28108382

      • Hepatocellular (liver), Breast & Colon rectal Cancer: mangostana fruit hulls..a natural cytotoxic agent against various cancers..the scientific rationale of using G. mangostana in anti-cancer treatment.  https://www.ncbi.nlm.nih.gov/pubmed/28108382

      • Pancreatic Cancer: induced apoptosis (cell death) https://www.ncbi.nlm.nih.gov/pubmed/28822990

      •  Protective effects against (a chemo therapy) doxorubicin-induced CARDIOTOXICITY by antioxidant, anti inflammatory, & antiapoptotic effects in human chemotherapy without reduction in its anticancer effect https://pubmed.ncbi.nlm.nih.gov/34962009/

      •  Mangosteen suppresses COLON CARCINOGENESIS (The process by which normal cells are transformed into cancer cells.) https://pubmed.ncbi.nlm.nih.gov/34802869/

      • Breast Cancer: mangosteen ‘may be used as food supplement or a potential therapeutic compound for breast cancer’. It ‘induces apoptosis in human breast cancer’  https://www.ncbi.nlm.nih.gov/m/pubmed/26892433/

      • Inhibits stops proliferation: of human cancers https://www.ncbi.nlm.nih.gov/pubmed/23811100

      • Oral Cancer considerable potential for the treatment of oral cancer.  https://pubmed.ncbi.nlm.nih.gov/29039600/

      • Skin melanoma and squamous cell carcinoma: anti invasion, suppressed the metastatic processes   https://www.ncbi.nlm.nih.gov/pubmed/22993323

      • Breast and LUNG Cancer: NEW Xanthones discovered. Compound 5 showed significant cytotoxic potential against epithelial lung carcinoma and breast carcinoma cell lines. https://www.ncbi.nlm.nih.gov/pubmed/29307236

      • Ovarian Cancer: apoptosis and suppressing migration and invasion in ovarian cancer cells.  https://www.ncbi.nlm.nih.gov/pubmed/28878295

      • Breast and PROSTRATE cancer: breakdown of which xanthones work the best killing the cancer  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693070/

      • Cervical Cancer: Mangostin showed the strongest suppression of human cervical cancer  https://www.ncbi.nlm.nih.gov/m/pubmed/26781450/

      • PROSTRATE: Inhibits prostate cancer. Good for prevention and treatment https://www.ncbi.nlm.nih.gov/pubmed/31782573/

      • Anti tumor for glioblastoma & squamous cell PLUS, https://www.ncbi.nlm.nih.gov/pubmed/31542481

      • Protective Anti-Inflammatory Activity Against Acute Lung Injury and Its Potential Cytotoxicity to Epithelial Lung and Breast Carcinomas
        https://pubmed.ncbi.nlm.nih.gov/31218570/

      • BREAST CANCER LINES: showed a significant reduction in cell adhesion that did not stimulate cell migration but, on the contrary, blunted cell motility. www.ncbi.nlm.nih.gov/pubmed/29333084

      • Thai Doctors unveil successful use mangosteen product with cancer patients. https://www.youtube.com/watch?v=W03Hi-ErqhM\

      • Proving that concentrated extracts from mangosteens contain anti-cancer properties.  https://www.pattayamail.com/features/special-report-thai-scientists-unveiled-mangosteens-anti-cancer-properties-15402

      •  Primary LIVER CANCER results: mangosteen has been reported for its cell-death induction and its chemosensitizing and anti-metastatic properties in MANY cancer cell types, such as OVARIAN cancer, LUNG cancer, and hepatocellular  carcinoma. https://www.ncbi.nlm.nih.gov/pubmed/30195041

      • Apoptosis & significant anti-metastatic effect in anti-small-cell neuroendocrine carcinomas in a very aggressive form of prostrate cancer https://www.ncbi.nlm.nih.gov/pubmed/30340816

      • Late stage APOPTOSIS “It is noteworthy that the new compound can promote cells apoptosis in late stage, having a remarkable inhibition effect..” https://www.ncbi.nlm.nih.gov/pubmed/28441346

      • Bile Duct CANCER cholangiocarcinoma: “α-mangostin from Garcinia mangostana pericarp could inhibit CCA cell proliferation by inducing apoptosis.. and inhibit metastasis. Moreover, α-mangostin could inhibit CCA growth, i.e. reduce tumor mass (weight and size).”  https://www.ncbi.nlm.nih.gov/pubmed/28441703

      • Efflux/detox the body from drug build up including chemo naturally with the mangosteen that is also be cancer preventative and anti tumor https://www.ncbi.nlm.nih.gov/pubmed/28641010

      • Promising strategy against Melanoma https://pubmed.ncbi.nlm.nih.gov/29168273/

      • Inhibits skin cancer https://pubmed.ncbi.nlm.nih.gov/28582759/

      •  Inhibit the tumor growth of cervical cancer cells https://pubmed.ncbi.nlm.nih.gov/28537893/

      • KIDNEY CANCER α-mangostin suppresses cell migration and invasion… a promising anti-metastatic https://pubmed.ncbi.nlm.nih.gov/29190630/

      • Tongue Cancer: “α-mangostin induces the apoptosis of …tongue carcinoma cell” http://www.ncbi.nlm.nih.gov/m/pubmed/26951885/

      • Lung Cancer: “a natural xanthone, was isolated from Garcinia mangostana…Apoptosis in Lung Cancer Cells and Decreases Tumor Growth” www.ncbi.nlm.nih.gov/m/pubmed/26310849/

      • Colon Cancer http://www.ncbi.nlm.nih.gov/pubmed/23239542

      • Bladder Cancer http://www.ncbi.nlm.nih.gov/pubmed/23682785

      • Leukemia http://www.ncbi.nlm.nih.gov/pubmed/23734655

      • Stomach Cancer http://www.ncbi.nlm.nih.gov/pubmed/24976157

      • Tongue Cancer http://www.ncbi.nlm.nih.gov/pubmed/24660467

      • Liver Cancer (hepatocellular) Anti tumor http://www.ncbi.nlm.nih.gov/pubmed/23927480

      • Eradicate liver cancer cells https://pubmed.ncbi.nlm.nih.gov/25955534/

      • A summary available to purchase of the work that has been done to explore ANTICANCER & ANTI TUMOR activities of α-mangostin, lesser xanthones, and mangosteen extracts in vitro, in vivo, & in humans in various cancers https://pubmed.ncbi.nlm.nih.gov/34896543/

      • Antioxidants & other nutrients do not interfere with chemotherapy or radiation therapy & can increase (cancer) kill & increase Patient survival https://pubmed.ncbi.nlm.nih.gov/17283738/

I am fascinated by mangosteen research since 2006 & aim to maintain this archive of studies.

Check out the Table 1 & 2 AT THIS LINK  for remarkable compilation of medical benefits https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368837/

GRATEFULLY, for prevention, I use XANGO WHOLE FRUIT FORMULA MANGOSTEEN in my daily supplement regimen. It contains all the XANTHONES from the rind/pericarp that are mentioned in the research studies. Select your market & BUY XANGO HERE.   

There are 2 whole fruit formulas: the Classic Xango & the Reserve which is more xanthone rich. 

PLEASE NOTE the article is based on current published research only. *None of the above statements have been evaluated by the FDA. This article, & all products mentioned at this blog, are not intended to diagnose, treat, cure or prevent any disease.