Science

The science behind blue nevus melanoma 

Blue nevus melanoma (BNM) is a rare form of melanocytic neoplasm. Unlike cutaneous melanoma, BNM is not associated with sun damage. Rather, BNM arises from a pre-existing benign blue nevus often on the scalp, neck, or trunk in both men and women usually in their 50s. Statistics on its prevalence are limited due to its rarity and its biology is poorly understood. BNM harbors specific mutations in the G-coupled proteins (GNAQ or GNA11) and in tumor suppressor protein (BAP1). It exhibits a significant genetic similarity only with uveal melanoma, another rare type of melanoma, but not with cutaneous melanoma. Currently, there is no drug treatment/development  specifically design for BNM.

Publications related to blue nevus melanoma:

https://pmc.ncbi.nlm.nih.gov/articles/PMC7572824/

https://www.sciencedirect.com/science/article/pii/S0893395222007748

Clearly there is not enough scientific knowledge existing right now around blue nevus melanoma. Our goal is to cure that. Please notify us of other interesting publications relevant to blue nevus melanoma. This website is continuously under construction and will be updated on an on-going basis.

The blue nevus melanoma ribbon is black for melanoma with blue dots symbolizing the blue nevi from which the melanoma arises.