Projects

Drug Repurposing

Project Ruby

Personalized Cancer Vaccine

Project Emerald

Novel Drug Discovery

Project Sapphire

Project Ruby involves high-throughput screening of existing drugs against relevant cell lines/organoids.

Project Emerald involves supporting efforts for generation of personalized cancer vaccines.

Project Sapphire involves drug discovery against a known blue nevus melanoma targets (GNA11/Q and BAP1).

We support work done by UCSF's Drs. Aashish Manglik, Michelle Arkin, and Boris Bastian towards developing targeted therapies for blue nevus and uveal melanomas by targeting mutated G alpha protein (GNA11/Q).

We support work done by UCSF's Dr. Max Krummel towards developing personalized cancer vaccines.

Directly Targeting Gq/11 Proteins for Uveal Melanoma Therapy | The Mark Foundation for Cancer ResearchUveal melanoma is a rare but highly lethal eye cancer in which more than half of patients develop metastatic disease with poor long-term survival. Therapeutic options are limited…

Max Krummel, PhD - Parker Institute for Cancer ImmunotherapyMatthew (Max) Krummel is a Professor in the Pathology Department at University of California, San Francisco. He specializes in Systems Immunology and his research projects are aimed at understanding how cells work together to generate immunity. His lab use real-time microscopic methods to image the dynamic movement of lymphocytes and lymphocyte receptors during antigen recognition. They … Continued

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