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Professors
Tenure Track Researcher (RTT)
Post Docs
PhD students
Monica Mura
email: m.mura43@studenti.uniss.it
Project: Effect of electrolytes on biointerfaces
Monica Mura got master's degree in Chemical Science at the University of Cagliari with first class honours under the supervision of Prof. A. Salis. Her master's thesis is entitled "Nanoantibiotic: Design of multifunctional MSN nanosystems containing both antibiotic and copper ions to combat bone infection." It has been carried out within the research lines of the Intelligent Biomaterials Research Group (GIBI-UCM) led by Prof. M. Vallet Regi in the Department of Chemistry in Pharmaceutical Sciences of the Universidad Complutense de Madrid during a 6-month internship funded by Erasmus+ scholarship. In Semptember 2020 she won a PhD. scholarship in Chemical Sciences and Technologies at the University of Cagliari under the supervision of Prof. A. Salis. Her research project aims to study the effect of electrolytes on biointerfaces.
Matteo Farci
email: matteofarci.chem@gmail.com
Project: Theoretical and computational studies of elecrochemical systems
Matteo got his bachelor's and master's degrees, in chemistry and chemical science respectively, at University of Cagliari.
In his bachelor and master thesis he worked in the field of molecular modeling under the supervision of Prof. P. Ruggerone at the Department of Physics in Cagliari, with the aim of assessing different open-source software of protein-ligand and protein-protein docking and use them to investigate biological systems.In his master's thesis titled "Protein-protein interactions in synaptic junctions" he studied the interaction between Shank3 and Homer1, two proteins involved in various neurological and neurodevelopmental diseases.
Matteo also collaborated with Prof.ssa F. Mocci (Department of Chemistry in Cagliari) to study the stability of DNA G-quadruplex with different ligands. In this work he used the method of molecular dynamic.
In November 2022 Matteo won a PhD. scholarship in Chemical Sciences and Technologies at the University of Cagliari under the supervision of Prof. D. F. Parsons. His research work consists of developing codes, mainly in Python, and mathematical models for the study of electrochemical systems.
Visiting PhD students
Ahlem ben Saad
Project: Betalains....
Master Students
Francesca Cherchi
Project: Interactions between telomerase-inhibiting drugs and DNA through UV-Vis spectroscopy
Francesca Cherchi is a MSc student in Chemical Sciences at the University of Cagliari. Her thesis research topic involves the study of interactions between novel telomerase-inhibiting drugs and DNA, in both duplex and telomeric quadruplex (G4) form. The selected molecules are porphyrins and acridines, potentially active against a variety of tumors. The main experimental technique used is UV-Vis spectroscopy, which will be supported by DLS/ELS measurements and SAXS analyses. Spectrophotometric titrations and thermal melting curves will be executed to determine binding constants and denaturation temperatures, respectively. The data will be used to compare the behavior of various molecules with duplex and quadruplex, and ultimately determine the best candidate for biological experimentation.
Alessandra Ballicu
Project: Structure and function of the protein corona on the surface of nanoparticles
Alessandra Ballicu graduated from the University of Cagliari in 2022 with a thesis titled "Study of the mobility and potential bioavailability of arsenic and some metals in solid matrices from abandoned mining areas".
Currently, she is carrying out a thesis internship within Erasmus+ program within a collaboration between Bionanointerfaces Group and the Jerzy Haber Institute of Catalysis and Surface Chemistry at the Polish Academy of Sciences in Kraków, Poland. Her research project focuses on studying the structure and function of the protein corona on the surface of nanoparticles, with significant implications for the biocompatibility, using phisico-chemical techniques like DLS, zeta potential, QCM, FTIR and Circular Dicroism spectroscopies.
Gaia Meloni
Project: Project: Study of the interactions between bovine serum albumin and mesoporous silica nanoparticles at the isoelectric point.
Her MSc thesis concerns the study of interactions between a model protein (bovine serum albumine, BSA) and bare and functionalized mesoporous silica nanoparticles (MSN). Her tasks consists of: synthesis and charaterization of MSN using light scattering techniques (DLS, ELS), SAXS, nitrogen physisorption (BET), determination of kinetics and equilibrium parameters through UV-vis adsorption isotherms at BSA's isoelectric pointStructure and function of the protein corona on the surface of nanoparticles.
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