Former Group members

Post Docs

Dr. Alessandro Pira

email: alessandro.pira@unica.it 

 

Project: Immobilisation of Enzymes for Biocatalytic Flow Reactors.

 

He Studied at University of Cagliari, in 2011 he got the Bachelor's Degree in Chemistry with a thesis entitled “Statistical Analysis of Molecular Dynamics Simulations of Globular Proteins” under the supervision of Prof. Mariano Casu and in 2014 the Master's Degree in Chemical Sciences with first class honours with a thesis entitled “Molecular Dynamics Simulations Study of the Structure of Dendrimeric Peptides and their Interaction with Mixed Micelles” under the supervision of Dr. Mariano Andrea Scorciapino.

During his PhD, he won a scholarship research funded by IMI innovative medicine initiative within the research project “Molecular Basis of the Outer Membrane Permeability-Translocation" against bacterial resistance, under the supervision of Prof. Matteo Ceccarelli at Department of Physics of University of Cagliari. He spent three months at UCL, University College London working with Prof. Francesco Luigi Gervasio in order to study in deep theoretical aspects of computational method used for his research. In 2019 he got PhD with the thesis “Structural Properties of β-Lactamase Inhibitors: Computational Study to Enhance Permeability through General Porins of Gram-Negative Bacteria” under the supervision of Prof. Mariano Casu, Prof. Matteo Ceccarelli and Dr. Mariano Andrea Scorciapino at University of Cagliari.

After the PhD, he took a postdoc position for a work in the field of experimental physics of solid state with a project entitled “Study and Characterization of the Impregnation Process in Porous Silicon with Organic and Inorganic Materials” at Department of Physics of University of Cagliari in the PoroSi Lab of Dr. Guido Mula. The main goal was to improve production process and photocurrent and sensors properties of built hybrid devices.

Currently, his postdoctoral project is funded by CRUI within the project “Go For IT” under the supervision of Prof. Andrea Salis at Bionanointerfaces & Biocatalysis - Salis' Lab of University of Cagliari. The research work involves the development of heterogeneous enzymatic biocatalysts for the realization of flow bioreactors. About that, the synthesis of solid supports based on mesoporous silica, both in the form of microparticles and monoliths, of biocatalysts obtained by enzyme entrapment within metal organic frameworks (MOFs) and their chemical-physical characterization will be carried out. The work is in collaboration with Prof. Edmond Magner at the Bernal Institute of University of Limerick. The most promising biocatalysts will be used for the realization of flow bioreactors and tested for the synthesis of products of pharmaceutical interest.


PhD students

Rossella Delpiano

email: rossella.delpiano@unica.it 

Project: Adsorption and degradation of pollutants through nanostuctures and immobilized enzymes

Bachelor's degree in chemistry in 2013, under the supervision of Prof Angelo Frongia and Prof Jean Ollivier, with a thesis entitled "Development of a protocol for the synthesis of α-amino benzocyclobutanones using an Amadori-Heyns type rearrangement" written following a 6-month internship funded by Erasmus scholarship at Laboratoire de Synthése Organique et Métodologie, Institut de Chimie Moléculaire et des Matériaux d'Orsay (Université Paris Sud XI).

In 2016 she obtained a master's degree in Chemical Sciences at the University of Cagliari, under the supervision of Prof Andrea Salis, with a thesis entitled “Assembly of multicomponent nano-bioconjugates composed of mesoporous silica nanoparticles, proteins and gold nanoparticles”, from which she published her first research paper (DOI : 10.1021/acsomega.9b01240).

During the years 2016 and 2017 she worked at the Physics Department of the University of Cagliari with a research contract relating to a project for the synthesis of fluorescent nanosensors, under the supervision of Prof Carlo Maria Carbonaro, with whom she still occasionally collaborates.

In 2017 she started her PhD (currently in progress) in Chemical Sciences and Technologies at the University of Cagliari under the supervision of Prof Andrea Salis, in collaboration with the research group of Prof Edmond Magner of the Bernal Institute of the University of Limerick (Ireland) and with the Portovesme srl industry based in Portoscuso (Italy).

Her research project focuses on environmental remediation. In particular, in particular she deals with the adsorption and degradation of pollutants through nanostructures and immobilized enzymes. In 2017 she worked for a short period in the research laboratory of Prof Liana Muresan and Graziella L. Turdean at the Faculty of Chemistry and Chemical Engineering of the Babeş-Bolyai University of Cluj Napoca (Romania), thus starting a new collaboration.

During these years she has published two other research papers titled respectively “Adsorption of Cu2+ and Zn2+ on SBA-15 mesoporous silica functionalized with triethylenetetramine chelating agent” (DOI : 10.1016/j.jece.2019.103205) and “Improving Metal Adsorption on Triethylenetetramine (TETA) Functionalized SBA-15 Mesoporous Silica Using Potentiometry, EPR and ssNMR” (DOI : 10.1002/admi.202000544) (collaboration with Division of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, 23955‐6900 Saudi Arabia). A fourth manuscript has been just published.

Davide Tocco

email: davide.tocco@unica.it 

Project: Enzymes immobilization in nanostructures for biofuels

Davide Tocco graduated at University of Cagliari-Italy (MSc) in 2018 with first class honours under the supervision of Prof. A. Salis. He spent 5 months for his internship at University of Limerick (Ireland) under the supervision of Prof. Dean E. Magner. At the University of Limerick he performed research on the preparation and characterization of Metal Organic Framework (MOF) for the use in biocatalysis. For this extent he examined the catalytic activity of the enzyme alcohol dehydrogenase (ADH), both immobilised and free. In 2019, He won a Ph.D. Scholarship PON-Cycle XXXIV (2019-2021) with a project entitled “Biofuels from biocatalysis: the importance of enzyme immobilization”.

His research focuses on the immobilization of enzymes within MOF, in particular fungal Laccases for delignification of lignocellulosic biomass and Lipases to produce biodiesel from exhaust oils. Currently, he was awarded a DAAD Scholarship and he is going to spend 7 months at Universität Erlangen-Nürnberg under Prof. Martin Hartmann supervision to develop a biocatalytic processes to obtain cellulose from lignocellulosic biomass, to be used to produce bioethanol.

Dr. Valentina Nairi

Dr. Federica Pitzalis

Visiting PhD students

Nastaran Arab (Iran)

Project: Enzymatic electrochemical biosensors

Nastaran Arab is pursuing Ph.D. degree in analytical chemistry at Alzahra University. She received her BSc. degree in Pure Chemistry and her M.Sc. degree in Analytical Chemistry from the Damghan University in 2013 and 2016 respectively. Her Master’s thesis was focused on the development of ion-selective electrodes. In February 2022 she won YITP scholarship in Chemical Sciences and Technologies at the University of Cagliari with a project entitled “Enzymatic electrochemical biosensors". Currently, She is working on a doctoral dissertation in the field of electrochemistry under Prof. Fotouhi's supervision.  Her research interests include fabricating electrochemical sensors and electrochemiluminescence sensors.


Magdalena Szota (YITP Fellow)

E-mail: magdalena.szota@ikifp.edu.pl

Project: Development of smart nanostructures based on polyelectrolytes and proteins

Magdalena Szota is a PhD student at the Institute of Catalysis and Surface Chemistry Jerzy Haber PAS. She graduated from the Krakow University of Technology (MSc) in 2019 in the field of biotechnology. In her master's thesis, she worked on Controlled Drug Delivery Systems (CDDS). Currently, she is preparing a doctoral dissertation in this field of nanotechnology, under the supervision of Prof. Barbara Jachimska. Its main research areas are the physicochemistry of colloidal systems, in particular the physicochemical characteristics of dendrimers and proteins in the context of their interactions with anticancer drugs.

Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Niezapominajek 8, 30-239 Krakow, Poland.


Sarka Sovova (Czech Republic)

Project: protein corona on silica nanoparticles

Sarka Sovova is a PhD student at Brno University of Technology, Faculty of Chemistry. Her research is now focused on nanoparticles characterization and their interaction with protein. She graduated at the same faculty in 2017 in the field of physical chemistry. During her masters study, she stayed at NTNU in Trondheim, Norway, where she also finished her master thesis (The interaction of DNA and surfactant in the presence of crowding agent). After that, she started PhD study at Brno University of Technology, Faculty of Chemistry and in 2019 and 2020 she took a short-term internship at Gent University, Faculty of Bioscience Engineering, Belgium. She worked there on the synthesis and characterization of CaCO3 particles. In September 2021 she won YITP scholarship and spent one month at Cagliari University under supervison of prof. Salis and Dr. Carucci, followed by 2 weeks internship in May 2022. She worked on specific buffer effect on nanoparticles-protein interaction. Currently she is preparing her doctoral manuscript and going to submit it during fall 2022. 

Other Visiting MD/PhD/ Postdocs

Agnieszka Kaminska (Post Doc, Poland) Project: Protein Corona

Frederik Helgund (PhD, Denmark) Project: Polyelectrolytes

Maryam Naseri (PhD, Iran) Project: Enzyme@MOF

Master Students

Elena Caddeo

Michela Tozzi

Claudia Masala

Luca Puddu

Giovanni Russo

Giulia Sechi

David Andrea Collu

Giulia Francesca Musu

Monica Mura

Debora Todde

Luca Cappai

Luca Licheri

Davide Tocco

Davide Zanda

Rossella Delpiano

Olga Becconi

Michela Collu

Undegraduated Students

Nicola Scalas

Francesco Raccis

Alessandra Cogoni

Giulia Granitzio