BIODYNAMICS: TRANSDISCIPLINARY CHALLENGES

Jointly organized by the International Centre of Biodynamics (ICB) and the University of Bucharest under the aegis of the Romanian Academy

“Cellular dynamics: advances and challenges in multi-omics integration, single-cell and host-microbe interaction analysis”

Aim: Strengthen a collaborative center of excellence in Biodynamics, fostering synergy among researchers in multi-omics, high-resolution cellular dynamics, and microbe-host interactions. Together, we strive to uncover the principles that govern living systems and translate this knowledge into transformative biomedical innovations.

How: An open format, combining lectures with round table discussions for feeding future trans-disciplinary collaborations.

Who: As for the last edition (2022, Bucharest - https://sites.google.com/view/biodynamics2022/home), this event will gather top-level international scientists with contributions aligned with the symposium's topics and biodynamics related fields, from Cell & Molecular Biology to Chemistry, Physics, Medicine, (bio)Engineering, Bioinformatics and AI.

A transdisciplinary approach is increasingly recognized as essential for addressing urgent biomedical challenges, including resistance in pathogens, microorganisms, and tumor cells. Rather than simply fostering collaboration between separate disciplines, it builds a shared framework in which biological mechanisms, computational models, clinical evidence, technological tools, and societal constraints are integrated into a unified problem-solving strategy.

Topics

1. Transdisciplinary approaches to quantifying the dynamics of cellular systems in developmental, healthy, and pathological states

2. Cell dynamics: from genotypic and phenotypic structure to function

3. Cell physiomics of microorganisms: a biomedical perspective on drug response

4. Assessment of pathogenic resistance

5. (AI assisted) Electron & Optical microscopy for quantifying cellular dynamics 

6. Biosensing platforms for cell dynamics analysis

Distinguished plenary talk

Key Participants:

(●) Claudiu Supuran, University of Florence, Italy (carbonic anhydrase inhibitors) (●) George Călin, MD Anderson, U. Texas, USA (microRNA) (●) Gradimir Misevic, Austria (glycan-glycan interactions) (●) Jean Louis Marty, University of Perpignan, ICB (biosensing) (●) Pietro Ferraro, ISASI, Italy (quantitative optical microscopy) (●) Adrian Podoleanu, University of Kent, UK (OCT) (●) Erik Reimhult, Institute of Colloid and Biointerface Science, Vienna (cryo-SEM analyses) (●) Huamin Tang, Nanjing Medical University, China (molecular immunology and virology) (●) Zhigang Zhu, University of Shanghai for Science and Technology (micro-needle based drug delivery system) (●) Peer Fischer, Max Planck Institute for Medical Research, Heidelberg (ulrasound-cell interaction, organoids) (●) Harald Alfred Stenmark, Oslo University Hospital (molecular mechanisms that promote or suppress cancer) (●) Eric Röttinger, Institute for Research on Cancer and Aging, Nice (stress-response, regeneration & longevity)

Other leading scientists are expected to confirm their participation.

The detailed program (under preparation) will offer ample room for lectures (40' - keynote, 30’ - invited, 20’ - regular & 5’ - short talks for students with poster presentations), round table discussions and access to laboratory test platforms* as an enabling breadboard for future transdisciplinary collaboration avenues.

*The recent advancements of ICB for phenotypic multi-dimensional analysis provide the suitable framework for the envisaged transdisciplinary interactions. The unique merger of label and label-free formats for high-resolution assessment of live cell functional dynamics at both single-cell and population levels available within ICB offer a breadboard platform for cell and molecular biology, genetics, and microbiology studies, as well as for drug-induced bio-effect analyses.

Note: The meeting of the International Advisory Board of ICB (https://www.biodyn.ro/php/biodyn.php?act=International-Advisory-Board&idm=2&idsm=36&locale=en) will be organized within the Symposium.

The Venue