Expertise

• Cellular and molecular studies of proteins and nucleic acids

• Structural studies of globular, disordered and membrane proteins

• Structural studies of non-canonical nucleic acid structures "G-quadruplexes"

• High-throughput RNA-sequencing (in vitro and in vivo)

• Biophysical and biochemical studies of proteins, nucleic acids, nucleoprotein complexes, and biological membrane mimetics :

Recombinant protein production, Recombinant DNA technology, Antibodies and application, Protein aggregation kinetics, Enzyme kinetics,     Electrophoresis, PCR, qPCR, in vitro gene expression.

Biophysical techniques: NMR, ITC, MST, DSC, Fluorescence, DLS, FT-IR, CD, HS-AFM, UV-Vis, TEM, AUC, SEC, HPLC, etc.

• Designing chemically stable peptide, protein and polymer lipid-nanodiscs for various applications including protein aggregation study

• Single-Molecule Fluorescence Microscopy

• Computational Modeling: Biomacromolecules (Protein, Nucleic Acids and Membrane), Small-molecules, and Polymers  

• Molecular Dynamics Simulation (Biomacromolecules)