Research

Bethanis' Structural Research Group is Member of Hellenic Crystallographic Association (HeCrA)

Website: www.hecra.gr , www.hecra.gr/hecra-young-researchers

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PROJECTS

EXTERNAL PROJECTS

iGEM Athens 2025

BOOKS

PUBLICATIONS

CYCLODEXTRINS

• Christoforides E., Andreou A., Koskina P., and Bethanis K. (2025) Selective Crystallization of Trans-Nerolidol in β-Cyclodextrin: Crystal Structure and Molecular Dynamics Analysis. Crystals, 15(9), 802
  https://doi.org/10.3390/cryst15090802

     [IF: 2.4, citations in Scopus: 0]

• Mazurek, A. H., Szeleszczuk, Ł., Bethanis K., Christoforides, E., Dudek, M. K., Zielińska-Pisklak, M. and Pisklak D. M. (2023). 17-β-Estradiol-β-Cyclodextrin Complex as Solid: Synthesis, Structural and Physicochemical Characterization. Journal of Molecular Structure, Volume 1313, 138710

     https://doi.org/10.1016/j.molstruc.2024.138710 

     [IF: 3.8, citations in Scopus: 1]

• Mazurek, A. H., Szeleszczuk, Ł., Bethanis K., Christoforides, E., Dudek, M. K., Zielińska-Pisklak, M. and Pisklak D. M. (2023). 17-β-Estradiol - β-Cyclodextrin Complex as Solid: Synthesis, Structural and Physicochemical Characterization. Molecules, 28(9), 3747

https://www.mdpi.com/1420-3049/28/9/3747

[IF: 4.927, citations in Scopus: 11]

• Christoforides, E., Andreou, A., Papaioannou, A. and Bethanis, K. (2022). Structural studies of piperine inclusion complexes in native and derivative b­-Cyclodextrins. Biomolecules, 12(12), 1762

https://www.mdpi.com//2218-273X/12/12/1762

[Publication under the IKY fellowship (2020–2022) and the INSPIRED Project ,IF: 6.064, citations in Scopus: 13]

• Bethanis, K., Christoforides, E., Andreou, A. and Eliopoulos, E. (2022). Molecular symmetry of permethylated b-cyclodextrins upon complexation. Symmetry, 14(10), 2214

https://www.mdpi.com/2073-8994/14/10/2214           

[Publication under the INSPIRED Project, IF: 2.940, citations in Scopus: 5]

• Hatziagapiou, K., Bethanis, K., Koniari, E., Christoforides, E., Nikola, O.,  Andreou, A., Mantzou, A., Chrousos, G. P., Kanaka-Gantenbein, C. and Lambrou, G. I. (2022). Biophysical Studies and In Vitro Effects of Tumor Cell Lines of Cannabidiol and its Cyclodextrin Inclusion Complexes. Pharmaceutics, 14(4), 706

https://www.mdpi.com/1999-4923/14/4/706 

[Publication under the INSPIRED Project, IF: 6.321, citations in Scopus: 16]

• Fourtaka, K., Christoforides, E., Tzamalis P. and Bethanis K. (2021). Inclusion of citral isomers in native and methylated cyclodextrins: Structural insights by X-ray Crystallography and Molecular Dynamics simulation analysis. Journal of Molecular Structure, Volume 1234, 130169

https://doi.org/10.1016/j.molstruc.2021.130169

[Publication under the INSPIRED Project, IF: 2.463, citations in Scopus: 12]

• Papaioannou A., Christoforides, E., and Bethanis K. (2020). Inclusion complexes of naringenin in dimethylated and permethylated b-cyclodextrins: X-ray crystallography and molecular dynamics studies. Crystals 10(1), 10

https://doi.org/10.3390/cryst10010010 

[Publication under the OPENSCREEN & INSPIRED Projects, IF: 2.061, citations in Scopus: 9]

• Christoforides E., Fourtaka K., Andreou A. and Bethanis K. (2020). X-ray crystallography and molecular dynamics studies of the inclusion complexes of geraniol with b-cyclodextrin, heptakis (2,6-di-O-methyl)-b-cyclodextrin and heptakis (2,3,6-tri-O-methyl)-b-cyclodextrin. Journal of Molecular Structure, 1202, 127350

https://doi.org/10.1016/j.molstruc.2019.127350

[Publication under the OPENSCREEN Project, IF: 2.120, citations in Scopus: 18]

• Bethanis, K., Christoforides, E., Tsorteki, F., Fourtaka K. and Mentzafos D. (2018). Structural studies of the inclusion compounds of a-naphthaleneacetic acid in heptakis(2,6-di-O-methyl)-b-Cyclodextrin and heptakis(2,3,6-tri-O-methyl)-b-Cyclodextrin by X-ray crystallography and molecular dynamics. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 92(1), 157-171

https://doi.org/10.1007/s10847-018-0824-y

[IF: 1.316, citations in Scopus: 10]

• Fourtaka, K., Christoforides, E., Mentzafos D. and Bethanis K. (2018). Crystal structures and molecular dynamics studies of the inclusion compounds of b-citronellol in b-cyclodextrin, heptakis(2,6-di-O-methyl)-b-cyclodextrin and heptakis(2,3,6-tri-O-methyl)-b-cyclodextrin. Journal of Molecular Structure 1161, 1–8

https://doi.org/10.1016/j.molstruc.2018.02.037

[IF: 1.753, citations in Scopus: 16]

• Christoforides, E., Papaioannou A. and Bethanis K. (2018). Crystal structure of the inclusion complex of cholesterol in b-cyclodextrin and molecular dynamics studies. Beilstein Journal of Organic Chemistry 14, 838–848

https://doi.org/10.3762/bjoc.14.69

[Publication under the IKY fellowship (2016–2017), IF: 2.34, citations in Scopus: 32]

• Hatziagapiou, K., Bethanis, K., Lambrou, G. I., Yannakopoulou, K., Karpusas, M., Braoudaki, M., Christoforides, E., Tsorteki, F., Milionis, V., Kavantzas, N., Tzortzatou-Stathopoulou, F. and Gemou-Engesaeth, V. (2017). Enhanced Gefitinib Cytotoxicity in the Presence of Cyclodextrins: In-Vitro and Biophysical Studies Towards Potential Therapeutic Interventions for Cancer. Journal of Biomedical Nanotechnology, 13(5), 522–533

https://doi.org/doi:10.1166/jbn.2017.2374

[IF: 4.521, citations in Scopus: 13]

• Christoforides, E., Mentzafos, D. and Bethanis, K. (2015). Structural studies of the inclusion complexes of the (+)- and (−)-borneol enantiomers in α- and b-cyclodextrin. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 81(1), 193–203.

https://doi.org/10.1007/s10847-014-0448-9

[Publication in the context of the Doctoral Dissertation, IF: 1.253, citations in Scopus: 18]

• Bethanis, K., Tzamalis, P., Tsorteki, F., Kokkinou, A., Christoforides, E. and Mentzafos, D. (2013). Structural study of the inclusion compounds of thymol, carvacrol and eugenol in b-cyclodextrin by X-ray crystallography. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 77(1), 163–173

https://doi.org/10.1007/s10847-012-0230-9

[IF: 1.426, citations in Scopus: 32]