The Bales Lab investigates the molecular and cellular mechanisms of the retinal neurovascular unit that facilitate both degeneration and neuroprotection. We utilize a 'whole network' approach, integrating sophisticated methods to seek interactions among vasculature, glia, retinal neurons, and the immune system. 

These retinal cells engage in complex molecular interactions that are essential for retinal homeostasis and visual function. Disturbances in these cellular communications can contribute to retinal disease onset and severity, such as age-related macular degeneration. Although these interactions are crucial, the molecular underpinnings of these cellular interactions in both health and disease remain elusive.

Research in the Bales Lab is all encompassing and includes basic, translational, and clinical studies. The Bales Lab seeks to uncover these molecular interactions with the ultimate goal of providing new methods and interventions for the treatment and or halting of retinal degenerative diseases.