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Avijeet Kulshrestha
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Avijeet Kulshrestha
  • Home
  • About
  • Research
  • Publications
  • Tools
  • Teaching
  • Contact
  • Highlights
    • Gallery
    • Poster
    • Blog
  • More
    • Home
    • About
    • Research
    • Publications
    • Tools
    • Teaching
    • Contact
    • Highlights
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Integrated Multiscale Protein Analysis of Conformational Transitions (IMPACT)

Multidimensional Temperature-Accelerated String Method
Helix to sheet transition captured using string method
SARS-CoV-2 spike protein driven membrane fusion
Kinetic accessibility vs thermodynamic stability
Role of conformational flexibility in shaping the conformational change landscape
Polyglutamine aggregation mechanism

I am a computational biophysicist studying multiscale phenomena in complex biological systems using molecular dynamics (MD) simulations. My work focuses on developing coarse-grained models and computational methodologies to access spatial and temporal regimes that are otherwise computationally intractable.

My primary research interest lies in integrating multiscale MD to address fundamental problems in membrane protein function and protein aggregation. Through this interdisciplinary approach, I aim to connect molecular-level simulations with experimentally observable biological behavior and mechanisms.

Explore my research, publications, and tools sections to learn more about my work.

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“I, a universe of atoms, an atom in the universe.” ― Richard P. Feynman

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