Publications

SELECTED RECENT PUBLICATIONS

Shachi Mishra, Naveen Parmar, Pragya Chandrakar, Chandra Prakash Sharma, Sajiya Parveen, Ravi P Vats, Anuradha Seth, Atul Goel*, Susanta Kar*

Design, synthesis, in vitro and in vivo biological evaluation of pyranone-piperazine analogs as potent antileishmanial agents (Eur. J. Medicinal Chemistry, 2021, 221, 113516).

https://www.sciencedirect.com/science/article/pii/S0223523421003652

Eur. J. Medicinal Chemistry, 2021, 221, 113516

Deepak Purohit, Chandra P Sharma, Ashutosh Raghuvanshi, Ankita Jain, Kundan S Rawat, Neeraj M Gupta, Jagriti Singh, Monika Sachdev, Atul Goel*

First Dual Responsive ‘Turn‐on’and ‘Ratiometric’AIEgen Probe for Selective Detection of Hydrazine both in Solution and Vapour Phase (Chem. Eur. J., 2019, 25, 4660–4664). https://onlinelibrary.wiley.com/doi/full/10.1002/chem.201900003

Chandra P. Sharma, Neeraj M Gupta, Jagriti Singh, Rohit A K Yadav, Deepak K. Dubey, Kundan S. Rawat, Ajay Kumar Jha, Jwo-Huei Jou, Atul Goel*

Synthesis of Solution-Processable Donor-Acceptor Pyranone dyads for White Organic Light Emitting Devices (J. Org. Chem. 2019, 84, 7674-7684.). https://pubs.acs.org/doi/10.1021/acs.joc.9b00293

Ashutosh Sharma, Ajay K. Jha, Shachi Mishra, Ankita Jain, Bhavana S. Chauhan, Manoj Kathuria, Kundan S. Rawat, Neeraj M. Gupta, Renu Tripathi, Kalyan Mitra, Monika Sachdev, Madan L. B. Bhatt and Atul Goel *

Imaging and Quantitative Detection of Lipid Droplets by Yellow Fluorescent Probes in Liver Sections of Plasmodium Infected Mice and Third Stage Human Cervical Cancer Tissues. (Bioconjugate Chem., 2018, 29 (11), 3606–3613). https://pubs.acs.org/doi/10.1021/acs.bioconjchem.8b00552

Shachi Mishra, Pallavi Awasthi, Jagriti Singh, Rahul Kumar Gupta, Vikram Singh, Ruchir Kant, Ram Jeet, Debabrata Goswami and Atul Goel*

White Light Induced E/Z-Photoisomerization of Diphenylamine-Tethered Fluorescent Stilbene Derivatives: Synthesis, Photophysical, and Electrochemical Investigation

(J. Org. Chem. 2018, 83, 7, 3669-3678). https://pubs.acs.org/doi/abs/10.1021/acs.joc.8b00033

Vikram Singh, Kundan S. Rawat, Shachi Mishra, Tanvi Baghel, Soobiya Fatima, Aijaz A. John, Navodayam Kalleti, Divya Singh, Aamir Nazir, Srikanta K. Rath and Atul Goel*

Biocompatible fluorescent carbon quantum dots prepared from beetroot extract for in vivo live imaging in C. elegans and BALB/c mice (J. Mater. Chem. B, 2018, 6, 3366-3371). https://pubs.rsc.org/ru/content/articlehtml/2018/tb/c8tb00503f

Shahida Umar, Ajay Kumar Jha, Deepak Purohit, Atul Goel,* Naphthyridine-Tetraphenylethene based Mechanochromic Fluorescent Probe for the Selective Detection of Ag (I) in Aqueous Medium. (J. Org. Chem., 2017, 82, 4766). http://pubs.acs.org/doi/abs/10.1021/acs.joc.7b00456

Ashutosh Raghuvanshi,#Ajay Kumar Jha,# Ashutosh Sharma, Shahida Umar, Shachi Mishra, Ruchir Kant, Atul Goel*, A Nonarchetypal 5,6-Dihydro-2H-pyrano[3,2-g]indolizine-based Solution-Solid Dual Emissive AIEgen with Multicolor Tunability. (Chem. Eur. J. 2017, 23, 4527). Frontispiece article.http://onlinelibrary.wiley.com/doi/10.1002/chem.201781962/pdf

Ashutosh Raghuvanshi, Ajay Kumar Jha, Manoj Kathuria, Bhanu Priya Awasthi, Deepak Purohit, Kalyan Mitra, Atul Goel*, New Visible Light Excitable Donor-Acceptor 7-Hydroxy-coumarins as Blue Fluorescent Probes for Selective Staining of Vacuoles in Yeasts and L. donovani. (J. Mat. Chem. B, 2017, 5, 2580). http://pubs.rsc.org/EN/content/articlehtml/2017/tb/c6tb03257e

Ashutosh Raghuvanshi, Amit Kumar, Jyoti Kureel, Abdul M Tyagi, Deepak Purohit, Pallavi Awasthi, Kamini Srivastava, Abnish K Gautam, Mohd Nizam Mansoori, Priyanka Shukla, Ruchi Saxena, Anila Dwivedi, Divya Singh,* and Atul Goel*,3-Piperidylethoxy pterocarpan: A Potential Bone Anabolic agents that Improve Bone Quality via ER mediated Pathway, (Mol. Cell. Endocrinol. 2017 448, 41-47) http://www.sciencedirect.com/science/article/pii/S030372071730179X?via%3Dihub

Gaurav Taneja, Chandra Prakash Gupta, Shachi Mishra, Rohit Srivastava, Neha Rahuja, Arun Kumar Rawat, Jyotsana Pandey, Anand P. Gupta, Natasha Jaiswal, Jiaur R. Gayen, Akhilesh K. Tamrakar, Arvind Kumar Srivastava and Atul Goel*, Synthesis of Substituted 2H-Benzo[e]indazole-9-carboxylate as Potent Antihyperglycemic Agent that May Act through IRS-1, Akt and GSK-3β Pathways, (MedChemComm, 2017, 8, 329) http://pubs.rsc.org/is/content/articlehtml/2017/md/c6md00467a

Ajay Kumar Jha, Shahida Umar, Rakesh Kumar Arya, Dipak Datta, Atul Goel*, Pyrano[3,2-c]julolidin-2-one: A Novel Class of Fluorescent Probe for Ratiometric Detection and Imaging of Hg2+ in Live Cancer Cells. (J. Mat. Chem. B, 2016, 4, 4934). http://pubs.rsc.org/en/content/articlehtml/2016/tb/c6tb01413e

Atul Goel,* Vijay Kumar, Yasmin Hemberger, Fateh V. Singh, Pankaj Nag, Michael Knauer, Ruchir Kant, Resmi Raghunandan, Prakas Ranjan Maulik, Gerhard Bringmann, Rotationally Hindered Biphenyls and Terphenyls: Synthesis, Molecular Dynamics, and Configurational Assignment, J. Org. Chem. 2016, 81, 10721−10732.http://pubs.acs.org/doi/full/10.1021/acs.joc.6b01804

Shahida Umar, Ajay Kumar Jha, Atul Goel*. Donor-Acceptor Fluorescent Molecular Rotors Appended with Benzocrown Ethers as Doubly Twisted Intramolecular Charge Transfer Based Ratiometric Acidic pH Sensors. (Asian J. Org. Chem. 2016, 5, 187) Cover page article. http://onlinelibrary.wiley.com/doi/10.1002/ajoc.201500521/full

Ashutosh Sharma, Shahida Umar, Parmita Kar, Kavita Singh, Monika Sachdev, and Atul Goel*, A New Class of Biocompatible Fluorescent Probe AFN for Fixed and Live Cell Imaging of Intracellular Lipid Droplets, (Analyst 2016, 141, 137-143)http://pubs.rsc.org/en/content/articlehtml/2016/an/c5an01623a

A Dual Colorimetric-Ratiometric Fluorescent Probe NAP-3 for Selective Detection and Imaging of Endogenous Labile Iron (III) Pools in C. elegans. Atul Goel,* Shahida Umar, Pankaj Nag, Ashutosh Sharma, Lalit Kumar, Shamsuzzama, Zakir Hossain, Jiaur R. Gayen, Aamir Nazir (Chem. Commun., 2015, 51, 5001) http://pubs.rsc.org/en/content/articlehtml/2015/cc/c4cc09798j

List of Publications:

1. Ram, V.J., Goel, A., Verma, M., Kaul, I.B., Kapil, A. (1994): Latent leishmanicidal activity of quinazolinones and 1,2,4‑triazoloquinazolinones. Bioorg. Med. Chem. Lett. 4, 2087-2090.

2. Ram, V.J., Goel, A., Nath, M., Srivastava, P. (1994): 5‑Cyano‑2‑thiouracils and their derivatives: A new class of leishmanicides. Bioorg. Med. Chem. Lett. 4, 2653-2656.

3. Ram, V.J., Goel, A., Patnaik, G.K. (1995): Tetraazaacenaphthene and tetraazaphenalene Derivatives: A new class of hepatoprotectants. Bioorg. Med. Chem. Lett. 5, 1541-1544.

4. Ram, V.J., Goel, A. (1996): Ring transformation reactions Part IV: 6‑Aryl‑3‑ methoxycarbonyl‑4‑methylthio‑2H‑pyran‑2‑one, A novel synthon for the synthesis of 1,3‑terphenyls from aryl ketones. Tetrahedron Lett. 37, 93-96.

5. Ram, V.J., Goel, A., Kandpal, M., Mittal, N., Goyal, N., Tekwani, B. L., Guru, P.Y., Rastogi, A.K. (1997): Tetraazaacenaphthene, tetraazaphenalene and 1,3,4‑thiadiazole derivatives as potential leishmanicides. Bioorg. Med. Chem. Lett. 7, 651-656.

6. Ram, V.J., Goel, A. (1997): Synthesis of dipyridinyls and terpyridinyls with phenyl spacers through carbanion induced ring transformation reactions. Chem. Lett. 1021-1022.

7. Sarkhel, S., Goel, A., Ram, V.J., Chaudhari, S., Maulik, P.R. (1997): Unusual substitution of SCH3 by OH group in 9,10‑dihydrophenanthrene. Acta Cryst.(C) 53, 1713-1715.

8. Ram, V.J., Goel, A. (1997): An expeditious synthesis of 9,10‑dihydrophenanthrene by condensation of 2H‑pyran‑2‑ ones with tetralone. J. Chem. Res. (S) 460-461.

9. Ram, V.J., Goel, A., Shukla, P.K., Kapil, A. (1997): Synthesis of thiophenes and thieno[3,2‑c]pyran‑4‑ones as antileishmanial and antifungal agents. Bioorg. Med. Chem. Lett. 7, 3101-3104 (Science Direct Top 25 Hottest Articles in Chemistry during January-March 2010).

10. Goel, A., Srivastava, P., Nath, M., Ram, V.J. (1998): Synthesis of 1,3‑teraryls through carbanion induced ring transformation of functionalized pyran‑2‑ones. Synthesis, 167-170.

11. Ram, V.J., Goel, A., Patnaik, G.K. (1998): Functionalized 1,3‑teraryls as a new class of hepatoprotectants. Bioorg. Med. Chem. Lett. 8, 469-472.

12. Nath, M., Srivastava, P., Goel, A., Ram, V.J. (1998): An expeditious synthesis of heteroarenes through carbanion-induced ring transformation reactions of suitable functionalized pyran‑2‑ones. Eur. J. Org. Chem. 2083-2088.

13. Ram, V.J., Goel, A (1999): An innovative approach to the synthesis of complex biaryls from suitably functionalized 2H-pyran-2-ones through ring transformation reactions. Synthesis, 467-470.

14. Ram, V. J., Goel, A. (1999): Past and present scenario of hepatoprotectants. Curr. Med. Chem. 217-254.

15. Ram, V.J., Goel, A. (1999): An innovative synthesis of unsymmetrical tetrahydrobinaphthyls, binaphthyls with a phenyl spacer and tetrahydroazabinaphthyls through ring transformation reactions of 6-naphthyl-2-pyrones. J. Org. Chem. 64, 2387-2390.

16. Ram, V.J., Goel, A. (1999): Present status of hepatoprotectants. Prog. Drug Res. 52, 55-101.

17. Ram, V.J., Goel, A., Srivastava, P. (2000): A novel synthesis of ferrocenylarenes and heteroarenes through ring transformation reactions. Synthesis, 813-816.

18. Goel, A., Mazur, S.J., Fattah, R.J., Hartman, T.L., Turpin, J.A., Huang, M., Rice, W.G., Appella, E., Inman, J.K. (2002): Benzamide-based thiolcarbamates: a new class of HIV-1 NCp7 inhibitors. Bioorg. Med. Chem. Lett. 12, 767-770.

19. Song, Y., Goel, A., Basrur, V., Roberts, P.E.A., Mikovits, J.A., Inman, J.K., Turpin, J.A., Rice, W.G., Appella, E. (2002): Synthesis and biological properties of amino acid amide ligand-based pyridinioalkanoyl thiolesters as anti-HIV agents. Bioorg. Med. Chem. 10, 1263-1273.

20. Ram, V.J., Goel, A., Sarkhel, S., Maulik, P.R. (2002): A convenient synthesis and hepatoprotective activity of imidazo[1,2-c]pyrimido[5,4-e]pyrimidine, tetraazaacenaphthene and tetraazaphenalene from cyclic ketene aminals through tandem addition cyclization reactions. Bioorg. Med. Chem. 10, 1275-1280.

21. Saxena, A.S., Goel, A., Ram, V.J. (2002): Regioselective synthesis of highly functionalized biaryls through carbanion induced ring transformation of 2H-pyran-2-ones. Synlett 1491-1492.

22. Agarwal, N., Saxena, A.S., Farhanullah, Goel, A., Ram, V.J. (2002): A diversity oriented synthesis of highly functionalized unsymmetrical biaryls through carbanion induced ring transformation of 2H-pyran-2-ones. Tetrahedron 58, 8793-8798.

23. Farhanullah, Agarwal, N., Goel, A., Ram, V.J. (2003): A concerted synthesis of aminonicotinonitriles and diaminopyridines through base catalyzed ring transformation of 2H-Pyran-2-ones. J. Org. Chem. 68, 2983-2985.

24. Schito, M.L., Goel, A., Song, Y., Inman, J.K., Fattah, R.J., Rice, W.G., Turpin, J.A., Sher, A., Appella, E. (2003): In vivo antiviral activity of novel human immunodeficiency virus-1 nucleocapsid p7 zinc finger inhibitors in a transgenic murine model. AIDS Res. Human Retroviruses 19, 91-101.

25. Sil, D., Goel, A., Ram, V.J. (2003): A convenient controlled synthesis of bent-core oligoarenes and heteroarenes through carbanion induced ring transformation of 2H-pyran-2-ones. Tetrahedron Lett. 44, 3363-3365.

26. Saxena, A. S., Goel, A., Ram, V. J. (2003): A convenient and expeditious synthesis of annulated N, S-heterocycles. J. Ind. Chem. Soc. 80, 311-318.

27. Ram, V. J., Srivastava, P., Goel, A. (2003): An innovative synthesis of bridgedhead azolo[3, 2-a]pyrimidines and imidazo[2,1-b]thiazines through ring transformation of 2H-pyran-2-ones. Tetrahedron 59, 7141-7146.

28. Upadhyay, D.N., Agarwal, N., Goel, A., Ram, V.J. (2003): A concise synthesis of pyrimidinophanes from 6-aryl-5-cyano-2-thiouracil. J. Chem. Res (S) 380-382.

29. Goel, A., Agarwal, N., Singh, F.V., Sharon, A., Tiwari, P., Dixit, M., Pratap, R., Srivastava, A.K., Maulik, P. R., Ram, V.J. (2004): Antihyperglycemic activity of 2-methyl-3,4,5-triaryl-1H-pyrroles in SLM and STZ models. Bioorg. Med. Chem. Lett. 14, 1089-1092.

30. Goel, A., Dixit, M. (2004): Amberlyst-15 catalyzed efficient synthesis of 5-acetyl-4-hydroxy-coumarone and 5-acetyl-6-hydroxy-coumarone: Crucial precursors for several naturally occurring furanoflavones. Synlett 1990-1994.

31. Goel, A., Dixit, M. (2004): An efficient synthesis of 4,5-dihydronaphtho[2,1-b]furan through a novel ring transformation of 2H-pyran-2-one. Tetrahedron Lett. 45, 8819-8821.

32. Goel, A., Dixit, M., Verma, D. (2005): An innovative synthesis of dibenzofurans through a carbanion-induced ring transformation reaction. Tetrahedron Lett. 46, 491-493.

33. Goel, A., Singh, F.V., Sharon, A., Maulik, P.R. (2005): Regioselective syntheses of 2-aminopyridine and 2-pyridinone through nucleophile-induced ring transformation reaction. Synlett 623-626.

34. Goel, A., Singh, F.V. (2005): Regioselective synthesis of functionally congested biaryls through a novel C-C bond formation reaction. Tetrahedron Lett. 46, 5585-5587.

35. Dixit, M., Tripathi, B. K., Srivastava, A.K., Goel, A. (2005): Synthesis of functionalized acetophenones as protein tyrosine phosphatase 1B inhibitors. Bioorg. Med. Chem. Lett. 15, 3394-3397.

36. Sharon, A., Pratap, R., Vatsyayan, R., Maulik, P.R., Roy, U., Goel, A., Ram, V.J. (2005): 6-Aryl-4-methylsulfanyl-2H-pyran-2-one-3-carbonitriles as PPAR- activators. Bioorg. Med. Chem. Lett. 15, 3356-3360.

37. Goel, A., Singh, F. V., Verma, D. (2005): Substituent-dictated concise synthesis of 4,6-disubstituted-N-alkyl-2-pyridones and 2-aminopyridines. Synlett 2027-2030.

38. Goel, A., Verma, D., Singh, F.V. (2005): A vicarious synthesis of unsymmetrical meta- and para-terphenyls from 2H-pyran-2-ones. Tetrahedron Lett. 46, 8487-8491.

39. Goel, A., Verma, D., Dixit, M., Raghunandan, R., Maulik, P.R. (2006): Acetyltrimethylsilane: A novel reagent for the transformation of 2H-pyran-2-ones to unsymmetrical biaryls. J. Org. Chem. 71, 804-807.

40. Singh, F. V., Kumar, R., Sharon, A., Broder, C. K., Howard, J.A.K., Goel, A., Maulik, P. R. (2006): Synthesis and X-ray structural studies of pyrimidin-2,4-dione and 2-thioxo-1H-pyrimidin-4-one bearing chloroethyl moiety. J. Mol. Structure 782, 55-59.

41. Singh, F. V., Vatsyayan, R., Roy, U., Goel, A. (2006):Arylanthranilodinitriles: A new biaryl class of antileishmanial agents. Bioorg. Med. Chem. Lett. 16, 2734-2737.

42. Dixit, M., Goel, A. (2006): Regioselective synthesis of functionalized naphtho[b]thiophenes through a ‘lactone methodology’. Tetrahedron Lett. 47, 3557-3560.

43. Dixit, M., Sharon, A., Maulik, P. R., Goel, A. (2006): A controlled synthesis of naturally-mimicking benzofurans and their corresponding dimers. Synlett 1497-1502.

44. Singh, F. V., Kumar, A., Goel, A. (2006): Synthesis of o,m-cymene-cored biaryls through a carbanion-induced ring transformation strategy. Tetrahedron Lett. 47, 7767-7770.

45. Yadava, U., Goel, A., Ram, V. J., Maulik, P. R. (2006): 5,8-Diethyl-6,9-dithioxo-2,3,5,6,8,9-hexahydro-1H-3a,5,8,9a-tetraazaphenalene-4,7-dione. Acta Cryst. Sec E 62, O4991-O4993.

46. Goel, A., Singh, F.V., Dixit, M., Verma, D., Raghunandan, R., Maulik, P.R. (2007): Highly efficient non-palladium-catalyzed controlled synthesis and X-ray analysis of functionalized 1,2-diaryl-, 1,2,3-Triaryl- and 1,2,3,4-Tetraarylbenzenes. Chem. Asian J. 2, 239-247.

47. Dixit, M., Tripathi, B. K., Tamrakar, A. K., Srivastava, A. K., Kumar, B., Goel, A. (2007): Synthesis of benzofuran scaffold-based potential PTP-1B inhibitors. Bioorg. Med. Chem. 15, 727-734.

48. Dixit, M., Raghunandan, R., Kumar, B., Maulik, P. R., Goel, A. (2007): One-pot regioselective synthesis of dihydronaphthofurans and dibenzofurans. Tetrahedron 63, 1610-1616.

49. Pratap, R., Kushwaha, S. P., Goel, A., Ram, V. J. (2007): An efficient synthesis of (E)-(2-arylpyrazino[1,2-a]pyrimidine-4-ylidene)acetonitriles and cyanomethyl appended pyrimidines. Tetrahedron Lett. 48, 549-553.

50. Singh, F. V., Joshi, M. D., Srivastava, A. K., Goel, A. (2007): Synthesis and in vivo antihyperglycaemic activity of nature mimicking furanyl-2-pyranones in STZ-S model. Bioorg. Med. Chem. Lett. 17, 2425-2429.

51. Pratap, R., Roy, A. D., Kushwaha, S. P., Goel, A., Roy, R., Ram, V. J. (2007): Guanidine and amidine mediated synthesis of bridgehead triazaphenalenes, pyrimidines and pyridines through domino reactions. Tetrahedron Lett. 48, 5845-5849.

52. Singh, F. V., Kumar, V., Goel, A. (2007): Regioselective synthesis of functionally crowded benzenes at room temperature through ring transformation of 2H-pyran-2-ones. Synlett 2086-2090.

53. Goel, A., Singh, F.V., Kumar, V., Reichert, M., Gulder, T.A.M., Bringmann, G. (2007): Synthesis, optical resolution, and configurational assignment of novel axially chiral quateraryls. J. Org. Chem. 72, 7765-7768.

54. Kumar, A., Singh, F. V., Goel, A., (2007): A regioselective palladium-free protocol for accessing unsymmetrical biaryls through ring transformation of 6-aryl--pyrones. Tetrahedron Lett. 48, 7283-7286.

55. Singh, F. V., Kumar, V., Kumar, B., Goel, A. (2007): Regioselective synthesis of 2-amino-isophthalonitriles through a ring transformation strategy. Tetrahedron 63, 10971-10978.

56. Kumar, A,. Singh, F.V., Goel, A. (2007): Regioselective synthesis of functionally hindered -methylstyrenes through ring transformation of 2H-pyran-2-ones with mesityl oxide. Tetrahedron Lett. 48, 8223-8226.

57. Singh, F. V., Dixit, M., Chaurasia, S., Raghunandan, R., Maulik, P. R., Goel, A. (2007): Substituent-controlled general approach to access arylated pyran-2-ones and pyrano[3,4-c]pyran-1,8-diones. Tetrahedron Lett. 48, 8998-9002.

58. Dixit, M., Saeed, U., Kumar, A., Siddiqi, M. I., Tamrakar, A. K., Srivastava, A. K., Goel, A. (2008): Synthesis, molecular docking and PTP1B inhibitory activity of functionalized 4,5-dihydronaphthofurans and dibenzofurans. Med. Chem. 4, 18-24.

59. Goel, A.; Dixit, M.; Chaurasia, S.; Kumar, A.; Raghunandan, R.; Maulik, P. R.; Anand, R. S. (2008): Vapor-Phase Processable Novel Nonplanar Donor-Acceptor Quateraryls for Blue-OLEDs. Organic Letters, 10, 2553-2556.

60. Goel, A., Chaurasia, S., Dixit, M., Kumar, V., Prakash, S., Jena, B., Verma, J. K., Jain, M., Anand, R. S., Manoharan, S. S. (2009): Donor-Acceptor 9-Uncapped Fluorenes and Fluorenones as Stable Blue Light Emitters. Org. Lett. 11, 1289-1292.

61. Kumar, V., Singh, F. V., Parihar, A., Goel, A. (2009): Highly convenient regioselective synthesis of functionalized arylated benzene from ketene-S,S-acetal under mild conditions at room temperature. Tetrahedron Lett., 50, 680-683.

62. Goel, A., Verma, D., (2009): An expeditious protocol for sesquiterpene-cored functionalized arenes from S-(-)-citronellal. Tetrahedron Lett. 50, 2086-2089.

63. Singh, F.V., Parihar, A., Chaurasia, S., Singh, A. B., Singh, S. P., Tamrakar, A. K., Srivastava, A. K., Goel, A. (2009): 5, 6-Diarylanthranilo-1,3-dinitriles as a new class of antihyperglycemic agents. Bioorg. Med. Chem. Lett., 19, 2158-2161.

64. Kumar, A., Dixit, M., Raghunandan, R., Maulik, P. R., Goel, A.* (2009): Reusable resin Amberlyst 15 catalyzed new convenient protocol for accessing arylated benzene scaffolds. Tetrahedron Lett. 50, 4335.

65. Bhargavan, B.; Gautam, A.; Singh, D.; Kumar, A.; Chaurasia, S.; Tyagi, A.; Yadav, D.; Sharan, J.; Singh, A.; Sanyal, S.; Goel, A.; Maurya, R.; Chattopadhyay, N. (2009): Methoxylated isoflavones, cajanin and isoformononetin, have non-estrogenic bone forming effect via differential mitogen activated protein kinase (MAPK) signaling. J. Cell. Biochem. 108, 388-399.

66. Goel, A., Ram, V. J., (2009): Natural and synthetic 2H-pyran-2-ones and their versatility in organic synthesis. Tetrahedron 65, 7865-7913.

67. Goel, A., Singh, S. P., Kumar, A., Kant, R., Maulik, P. R. (2009): Unprecedented ‘Bridged Annulation’ Approach to the Construction of 5,6-Dihydro-4H-benzo[kl]acridines. Organic Lett. 11, 5122-5125.

68. Kumar, A., Goel, A. (2010): Unprecedented ‘ring transformation-rearrangement’ of pyran-2-ones into 5,6-dihydropyran-2-ones through insertion of acetol. Tetrahedron Lett. 51, 961-965.

69. Rashmi Pandey; Abnish K Gautam; Biju Bhargavan; Ritu Trivedi; Gaurav Swarnkar; Geet K Nagar; Dinesh K Yadav; Manmeet Kumar; Preeti Rawat; Lakshmi Manickavasagam; Amit Kumar; Rakesh Maurya; Atul Goel; Girish K. Jain; Naibedya Chattopadhyay; Divya Singh (2010): Total Extract and Standardized Fraction from the Stem-Bark of Butea monosperma have osteoprotective Action: Evidence for the Non-Estrogenic Osteogenic Effect of the Standardized Fraction. Menopause, 2010, 17, 602-610.

70. Abdul M Tyagi,; Abnish K Gautam,; Amit Kumar; Biju Bhargavan; Kamini Srivastava; Ritu Trivedi; Dinesh K Yadav, S Saravanan, Caroline Pollet, Michel Brazier, Romuald Mentaverri, Rakesh Maurya, Naibedya Chattopadhyay, Atul Goel*, Divya Singh*: Medicarpin inhibits osteoclastogenesis and has nonestrogenic bone conserving effect in ovariectomized mice, Molecular and Cellular Endocrinology (2010) 325, 101-109.

71. Atul Goel,* Vijay Kumar, Sumit Chaurasia, Madhu Rawat, Ramesh Prasad, R. S. Anand: Synthesis, Electrochemical and Optical Properties of Novel and Stable Yellow Fluorescent Fluoranthenes, J. Org Chem., 2010, 75, 3656-3662 (Highlighted as significant paper in may-june2010).

72. Lakshmi Manickavasagam, Sonal Gupta, Smriti Mishra, Amit Kumar, Ashutosh Raghuvanshi, Atul Goel, Divya Singh and Girish Kumar Jain Determination of 3-Hydroxy pterocarpan, a novel osteogenic compound in rat plasma by liquid chromatography-tandem mass spectrometry: application to pharmacokinetics study, Biomedical Chromatography, 2011, 25, 843-850.

73. Atul Goel, Deepti Verma, Ramendra Pratap, Gaurav Taneja, Yasmin Hemberger, Michael Knauer, Resmi Raghunandan, Prakas Ranjan Maulik, Vishnu Ji Ram, Gerhard Bringmann: Partially Hydrogenated 7-Oxa[5]helicenes and [5]Helicenes– Synthesis, Structures, and Dynamics, Eur. J. Org. Chem. 2011, 2940-2947.

74. Abdul Malik Tyagi, Kamini Srivastava, Jyoti Kureel, Anuj Kumar Singh, Kunal Sharan, Amit Kumar, Atul Goel, Divya Singh: Premature T Cell Senescense in Ovx Mice is inhibited by repletion of Estrogen and Medicarpin: A Possible Mechanism for Alleviating Bone Loss, Osteoporosis International, 2012, 23, 1151-1161.

75. Atul Goel*, Vijay Kumar, Pankaj Nag, Vikas Bajpai, Brijesh Kumar, Charan Singh, Sattey Prakash, and R. S. Anand: Thermally Stable Nonaggregating Pyrenylarenes for Blue Organic Light-Emitting Devices, J. Org. Chem., 2011, 76, 7474-7481.

76. Biju Bhargavan, Divya Singh, Abnish Kumar Gautam, Jay Sharan Mishra, Amit Kumar, Atul Goel, Manish Dixit, Rashmi Pandey, Lakshmi Manickavasagam, Shailendra Dhar Dwivedi, Bandana Chakravarti, Girish Kumar Jain, Ravishankar Ramachandran, Naibedya Chattopadhyay, Sabyasachi Sanyal: Medicarpin, a Legume Phytoalexin, Stimulates Osteoblast Differentiation and Promotes Peak Bone Mass Achievement in Rats: Evidence for Estrogen Receptor -mediated Osteogenic Action of Medicarpin, J. Nutritional Biochemistry, 2012, 23, 27-38.

77. Atul Goel*, Amit Kumar, Ashutosh Raghuvanshi, Ram Jeet, Yasmin Hemberger, Michael Knauer, Jyoti Kureel, Anuj K. Singh, Abnish Gautam, Ritu Trivedi, Divya Singh, Gerhard Bringmann: Synthesis, optical resolution, absolute configuration, and osteogenic activity of enantiomerically pure pterocarpans, Org. Biomol. Chem. 2012, 10, 9583 (Cover page).

78. Atul Goel,* Vijay Kumar, Salil P. Singh, Ashutosh Sharma, Sattey Prakash, Charan Singh, R. S. Anand, Non-aggregating Solvatochromic Bipolar Benzo[f]quinolines and Benzo[a]acridines for Organic Electronics, J. Mater. Chem. 2012, 22, 14880-14888.

79. Atul Goel*, Amit Kumar, Ashutosh Raghuvanshi: Synthesis, Stereochemistry, Structural Classification and Chemical Reactivity of Natural Pterocarpans, Chemical Reviews, 2013, 113, 1614-1640.

80. Atul Goel,* Gaurav Taneja, Ashutosh Raghuvanshi, Ruchir Kant, Prakas R. Maulik: Diversity-Oriented General Protocol for the Synthesis of Privileged Oxygen Scaffolds: Pyrones, Coumarins, Benzocoumarins and Naphthocoumarins, Org. Biomol. Chem. 2013, 11, 5239.

81. Atul Goel, Amrita Parihar, Pratibha Mishra, Salil Varshney, Pankaj Nag, Muheeb Beg, Anil Gaikwad, and S. K. Rath, Design and Synthesis of Novel Pyranone-Based Insulin Sensitizers Exhibiting In Vivo Hepatoprotective Activity, Med. Chem. Commun., 2013, 4, 1532-1536.

82. J Kureel, M Dixit, A M Tyagi, M N Mansoori, K Srivastava, A Raghuvanshi, R Maurya, R Trivedi, A Goel and D Singh, miR-542-3p suppresses osteoblast cell proliferation and differentiation, targets BMP-7 signaling and inhibits bone formation, Cell Death and Disease, 2014, 5, e1050; doi:10.1038/cddis.2014.4

83. Atul Goel,* Ashutosh Sharma, Manoj Kathuria, Arindam Bhattacharjee, Ashwni Verma, Prabhat R. Mishra, Aamir Nazir, Kalyan Mitra, New Fluoranthene FLUN-550 as a Fluorescent Probe for Selective Staining and Quantification of Intracellular Lipid Droplets, Organic Letters 2014, 16, 756-759.

84. Atul Goel,* Pankaj Nag and Shahida Umar, New convenient synthesis of fluorescent 1,8-Naphthyridines and the metal-sensing properties of the dye, Synlett, 2014, 1542-1546.

85. Atul Goel,* Pankaj Nag, Neha Rahuja, Rohit Srivastava, Sumit Chaurasia, Sudeep Gautam, Sharat Chandra, Mohammad Imran Siddiqi, Arvind K. Srivastava, Discovery of Biaryl-4-carbonitriles as Antihyperglycemic Agents that may act through AMPK-p38 MAPK pathway, Mol. Cell. Endo. 2014, 394, 1-12.

86. Atul Goel*, Ashutosh Sharma, Madhu Rawat, R. S. Anand, and Ruchir Kant, Synthesis of Fluorescent C2-Bridged Teraryls and Quateraryls for Blue, Sky-Blue, and Green Color Light-Emitting Devices, J. Org. Chem. 2014, 79, 10873-10880.

87. Atul Goel,* Shahida Umar, Pankaj Nag, Ashutosh Sharma, Lalit Kumar, Shamsuzzama, Zakir Hossain, Jiaur R. Gayen, Aamir Nazir, A dual colorimetric-ratiometric fluorescent probe NAP-3 for selective detection and imaging of endogenous labile iron(III) pools in C. elegans, Chem. Commun. 2015, 51, 5001-5004.

88. Atul Goel,* Ashutosh Raghuvanshi, Amit Kumar, Abnish Gautam, Kamini Srivastava, Jyoti Kureel, Divya Singh, 9-Demethoxy-medicarpin promotes peak bone mass achievement and has bone conserving effect in ovariectomized mice: positively regulates osteoblast functions and suppresses osteoclastogenesis, Mol. Cell. Endocrinol. 2015, 411, 155-166.

89. Isha Taneja, KSR Raja, Muralikrishna Challagundla, Ashutosh Raghuvanshi, Atul Goel, Muhammad Wahajuddin, LC-ESI–MS/MS method for bioanalytical determination of osteogenic phytoalexin, medicarpin, and its application to preliminary pharmacokinetic studies in rats, J. Chromatograhy B, 2015, 1001, 9-16.

90. Ashutosh Sharma, Shahida Umar, Parmita Kar, Kavita Singh, Monika Sachdev, and Atul Goel*, A New Class of Biocompatible Fluorescent Probe AFN for Fixed and Live Cell Imaging of Intracellular Lipid Droplets, Analyst 2016, 141, 137-143.

91. Manisha Dixit, Ashutosh Raghuvanshi, Chandra Prakash Gupta, Jyoti Kureel, Mohd Nizam Mansoori, Priyanka Shukla, Aijaz A John, Kalyan Mitra, Dipak Purohit, Pallavi Awasthi, Divya Singh*, Atul Goel*, Medicarpin, a Natural Pterocarpan, Heals Cortical Bone Defect by Activation of Notch and Wnt Canonical Signaling Pathways, PLoS ONE, 2015, 10, e0144541.

92. Shahida Umar, Ajay Kumar Jha, Atul Goel*, Donor-Acceptor Benzocrown Ether Appended Fluorescent Molecular Rotors as Doubly Twisted-ICT Based Ratiometric Acidic pH Sensor, Asian J. Org. Chem. 2016, 5, 187-191. (Cover Page)

93. Jha, Ajay Kumar; Umar, Shahida; Arya, Rakesh Kumar; Datta, Dipak; Goel, Atul*, Pyrano[3,2-c]julolidin-2-ones: a novel class of fluorescent probes for ratiometric detection and imaging of Hg2+ in live cancer cells, J. Mater. Chem. B 2016, 4, 4934-4940.

94. Atul Goel,* Vijay Kumar, Yasmin Hemberger, Fateh V. Singh, Pankaj Nag, Michael Knauer, Ruchir Kant, Resmi Raghunandan, Prakas Ranjan Maulik, Gerhard Bringmann, Rotationally Hindered Biphenyls and Terphenyls: Synthesis, Molecular Dynamics, and Configurational Assignment, J. Org. Chem. 2016, 81, 10721−10732.

95. Gaurav Taneja, Chandra Prakash Gupta, Shachi Mishra, Rohit Srivastava, Neha Rahuja, Arun Kumar Rawat, Jyotsana Pandey, Anand P. Gupta, Natasha Jaiswal, Jiaur R. Gayen, Akhilesh K. Tamrakar, Arvind Kumar Srivastava and Atul Goel*, Synthesis of Substituted 2H-Benzo[e]indazole-9-carboxylate as Potent Antihyperglycemic Agent that May Act through IRS-1, Akt and GSK-3β Pathways, MedChemComm, 2017, 8, 329.

96. Ashutosh Raghuvanshi, Ajay Kumar Jha, Ashutosh Sharma, Shahida Umar, Shachi Mishra, Ruchir Kant, and Atul Goel*, A Nonarchetypal 5,6-Dihydro-2H-pyrano[3,2-g]indolizine-based Solution-Solid Dual Emissive AIEgen with Multicolor Tunability, Chem. Eur. J. 2017, 23, 4527-4531.

97. Ashutosh Raghuvanshi, Ajay Kumar Jha, Manoj Kathuria, Kalyan Mitra, and Atul Goel*, New Visible Light Excitable Donor-Acceptor 7-Hydroxy-coumarins as Blue Fluorescent Probes for Selective Staining of Vacuoles in Yeasts and L. donovani, J. Mater. Chem. B, 2017, 5, 2580-2587.

98. Ashutosh Raghuvanshi, Amit Kumar, Jyoti Kureel, Abdul M Tyagi, Deepak Purohit, Pallavi Awasthi, Kamini Srivastava, Abnish K Gautam, Mohd Nizam Mansoori, Priyanka Shukla, Ruchi Saxena, Anila Dwivedi, Divya Singh,* and Atul Goel*, 3-Piperidylethoxypterocarpan: A Potential Bone Anabolic agents that Improve Bone Quality via ER-P38MAPK mediated Pathway, Mol. Cell. Endocrinol. 2017 448, 41-47.

99. Shahida Umar, Ajay Kumar Jha, Deepak Purohit, and Atul Goel* , A Tetraphenylethene-Naphthyridine-Based AIEgen TPEN with Dual Mechanochromic and Chemosensing Properties, J. Org. Chem., 2017, 82, 4766-4773.

100. Shachi Mishra, Pallavi Awasthi, Jagriti Singh, Rahul Kumar Gupta, Vikram Singh, Ruchir Kant, Ram Jeet, Debabrata Goswami, Atul Goel*, White Light Induced E/Z-Photoisomerization of Diphenylamine-Tethered Fluorescent Stilbene Derivatives: Synthesis, Photophysical, and Electrochemical Investigation, J. Org. Chem., 2018, 83, 3669-3678.

101. G.R. Valicherla, K. Italiya, C.P. Gupta, S. Mishra, M. Riya-zuddin, A.A. Syed, S.K. Singh, S.Shahi, G.Taneja, Wahajuddin, A. Goel, J. R. Gayen, Evaluation of oral pharmaco-kinetics, in vitro metabolism, blood partitioning and plasma protein binding of novel antidiabetic agent, S009‐0629 in rats, Drug Development Research 2018, 79, 173-183.

102. Shachi Mishra, Vartika Vaishya, Jyotsana Pandey, Akhilesh K. Tamrakar and Atul Goel*, Design and Synthesis of 1,2,3,4-Tetrahydroisoquinoline Substituted 2H-Pyranones and 1,3-Teraryls as Antihyperglycemic Agents, Ind. J. Het. Chem. 2018, 28, 83-90. (Invited for Special Issue).

103. Vikram Singh, Kundan S. Rawat, Shachi Mishra, Tanvi Baghel, Soobiya Fatima, Aijaz A. John, Navodayam Kalleti, Divya Singh, Aamir Nazir, Srikanta K. Rath, Atul Goel*, Biocompatible Fluorescent Carbon Quantum Dots from Beetroot Extract for in vivo Live Imaging in C. elegans and BALB/c Mice, J. Mat. Chem. B, 2018, 6, 3366-3371.

104. Ashutosh Sharma, Ajay K Jha, Shachi Mishra, Ankita Jain, Bhavana S Chauhan, Manoj Kathuria, Kundan S Rawat, Neeraj M Gupta, Renu Tripathi, Kalyan Mitra, Monika Sachdev, Madan LB Bhatt, Atul Goel*, Imaging and Quantitative Detection of Lipid Droplets by Yellow Fluorescent Probes in Liver Sections of Plasmodium Infected Mice and Third Stage Human Cervical Cancer Tissues, Bioconjugate chemistry 2018, 29 (11), 3606-3613.

105. Atul Goel*, Ajay K Jha, AIEgens: Rockstars at the age of Adolescence, Indian J Chem., 2019, 58B, 137-139. (Invited for Special Issue).

106. Ajay Kumar Jha, Deepak Purohit, Chandra Prakash Sharma, Neeraj Mohan Gupta, Kundan Singh Rawat, Atul Goel*,A new pyrrolyl-pyranone based AIEgen with solution solid dual emissive property, Indian J Chem., 2019, 58B, 192-199. (Invited for Special Issue).

107. Deepak Purohit, Chandra P Sharma, Ashutosh Raghuvanshi, Ankita Jain, Kundan S Rawat, Neeraj M Gupta, Jagriti Singh, Monika Sachdev, Atul Goel*, First Dual Responsive ‘Turn‐on’and ‘Ratiometric’AIEgen Probe for Selective Detection of Hydrazine both in Solution and Vapour Phase, Chem.Eur.J., 2019, 25, 4660 –4664.

108. Chandra P. Sharma, Neeraj M Gupta, Jagriti Singh, Rohit A K Yadav, Deepak K. Dubey, Kundan S. Rawat, Ajay Kumar Jha, Jwo-Huei Jou, Atul Goel* , Synthesis of Solution-Processable Donor-Acceptor Pyranone dyads for White Organic Light Emitting Devices, J. Org. Chem. 2019, 84, 7674-7684.