All Publications

1. Pankaj Dagur, Suddhasattya Dey, Rajdeep Dey, Hardik Bhatt, and Manik Ghosh*. Laccaic Acid A: A Natural Anthraquinone with Potent Anticancer Activity against MDA-MB-231 Cells. Current Topics in Medicinal Chemistry 2026; 26(4): 329-342. (https://doi.org/10.2174/0115680266338478250314231400)

2. Dhrubo Ahmed Khan, Mohammad Ashik Sheikh, Raihan Rahman Imon, Md. Imtiaz, Shamin Ahmed, Harasit Gharami, Ryan V. Labana, Tajudeen O. Jimoh, Anand Gaurav, Maria L. Pereira, Muhammad Nawaz, Julieta Z. Dungca, Md. Nazmul Hasan, Manik Ghosh, Veeranoot Nissapatorn. Boesenbergia rotunda–Derived Phytochemicals as Potent Inhibitors of SARS-CoV-2 Papain–Like Protease (PLpro): Insights From Molecular Docking and Dynamic Simulation, Scientifica 2026, 1695824. https://doi.org/10.1155/sci5/1695824 

3. Sukumar Kotyan, Shankaranahalli N. Chandana, Doddabasavanahalli P. Ganesha, Banavase N. Lakshminarayana, Nefisath Pandikatte, Pran Kishore Deb, Manik Ghosh, and et al. Synthesis of Novel Arylhydrazones Bearing 8-Trifluoromethyl Quinoline: Crystal Insights, Larvicidal Activity, ADMET Predictions, and Molecular Docking Studies. Pharmaceuticals 2025, 18(12), 1804. https://doi.org/10.3390/ph18121804 

4. Manik Ghosh, Suddhasattya Dey, Arijit Mondal, Uma Ranjan Lal, Avijit Choudhury, Sudip Kumar Mandal and Sanjana Sharma. A Preparative-HPLC Method Development and Validation for the Estimation and Identification of Laccaic Acid-A, Laccaic Acid-B, and Laccaic Acid-D. Current Functional Foods 2025, 3 (2): E040724231610 DOI: https://doi.org/10.2174/0126668629296374240610113854

5. Sandip Dey, Manik Ghosh*, Abhimanyu Dev. Signalling and molecular pathways, overexpressed receptors of colorectal cancer and effective therapeutic targeting using biogenic silver nanoparticles.Gene 2025;936(5): 149099. (https://doi.org/10.1016/j.gene.2024.149099)

6. Priyanka Chandra, Swastika Ganguly, Pran Kishore Deb, Manik Ghosh*. Design of Novel Imidazole Derivatives as Potential Non-nucleoside Reverse Transcriptase Inhibitors using Molecular Docking and Dynamics Strategies, Current Pharmaceutical Design; Volume 31, Issue 1, Year 2025, e13816128322984. (https://doi.org/10.2174/0113816128322984240725055333)

7. Pankaj Dagur and Manik Ghosh*. Lac Dye: Beyond Textiles and Tradition, A Comprehensive Review of its Bioactive Potential. Pharmacognosy Magazine. 2025;0(0). (https://doi.org/10.1177/09731296241305858)

8. Gourav Kumar, Dev Mani Pandey, Manik Ghosh*, Stefano Dall'Acqua, Rashmi Gupta, Nishi Prakash Tiwari, Usman Mohd Siddique, Leena Vishwakrama, Sunil Kant Guleri, Uma Ranjan Lal, Supriya Dubey, Karanjin, A Promising Bioactive Compound Possessing Anti-cancer Activity against Experimental Model of Non-small Cell Lung Cancer Cells, Anti-Cancer Agents in Medicinal Chemistry; Volume 24, Issue 5, Year 2024, e061123223181. (https://doi.org/10.2174/0118715206255557231024095245)

9. Priyanka Chandra, Swastika Ganguly, Manik Ghosh*, Shashi Pandey, Subhendu Chakroborty, Tarun Yadav. Synthesis, Biological Evaluation and Molecular Modeling Studies of Novel Tribromo-substituted Imidazole Analogs Journal of Molecular Liquids 2024; 414(B): 126305 (https://doi.org/10.1016/j.molliq.2024.126305)

10. Dipon Roy, Priyanka Chandra, Manik Ghosh*, Arup Mondal, Pankaj Dagur, Mayur A. Patel, Sanjit Mandal, Rajiv Jash, Robina Khatun, Suddhasattya Dey. A Stability Indicating Assay Method for the Simultaneous Estimation of Doxylamine Succinate and Pyridoxine Hydrochloride in Bulk and Combined Dosage Form. Research Journal of Pharmacy and Technology 2023; 16(10):4559-7. (https://doi.org/10.52711/0974-360X.2023.00743)

11. Priyanka Chandra, Swastika Ganguly and Manik Ghosh*. In Silico Studies of Piperazinyl-4-Nitroimidazole Derivatives in the Non-Nucleoside Inhibitory Binding Pocket of Human Immunodeficiency Virus-1-Reverse Transcriptase Enzyme (https://doi.org/10.59467/IJHC.2023.33.29)

12. Rojalini Samanta, KK Pradhan, D Sen, Manik Ghosh*. Structure-based drug design-guided identification of estrogen receptor binders. Mol Divers 28, 1291–1303 (2024). (https://doi.org/10.1007/s11030-023-10657-z)

13. Rojalini Samanta and Manik Ghosh*. Optimization of Microwave-assisted Extraction Technique for Flavonoids and Phenolics from the Leaves of Oroxylum indicum (L.) Kurtz Using Taguchi L9 Orthogonal Design. Pharmacognosy Magazine. 2023;19(1):97-104. (https://dx.doi.org/10.1177/09731296221137407)

14. Pankaj Dagur, Gourav Rakshit, Murtuja Sheikh, Abanish Biswas, Parineeta Jha, Khattab Al-Khafaji & Manik Ghosh* (2022) Target prediction, computational identification, and network-based pharmacology of most potential phytoconstituent in medicinal leaves of Justicia adhatoda against SARS-CoV-2, Journal of Biomolecular Structure and Dynamics. (https://dx.doi.org/10.1080/07391102.2022.2059010)

15. Dagur Pankaj and Ghosh Manik* (2022) Evaluation of Antiproliferative Activity of Lac dye fractions against MDA-MB-231 and SIHA Cell Lines, Anti-Cancer Agents in Medicinal Chemistry. (https://dx.doi.org/10.2174/1872210516666220224095221)

16. Suddhasattya Dey; Sudip Kumar Mandal; Mithun Bhowmick; Manik Ghosh; Pankaj Dagur; Shreya Shah; Biplab Kumar Dey. Development and Validation of a Dual Column HPLC Method for Determination of Albendazole and Its Metabolites in Rat Plasma. Egyptian Journal of Chemistry, 2022, 65(2), 209–221.  (https://dx.doi.org/10.21608/ejchem.2021.84205.4130)

17. Chanchal Kumar Mishra, Ashok Kumar Pattnaik, Pankaj Dagur, Dhiraj Kumar, Manik Ghosh*. Excision and incision wound healing activity of apigenin (4',5,7-trihydroxyflavone) containing extracts of Carissa carandas Linn. fruits. Pharmacognosy Magazine. 2022;18(78):502-509. (https://phcog.com/article/view/2022/18/78/502-509)

18. Rakshit, Gourav; Dagur, Pankaj; Satpathy, Swaha; Patra, Arjun; Jain, Alok; Ghosh, Manik*.Flavonoids as potential therapeutics against novel coronavirus disease-2019 (nCOVID-19).J Biomol Struct Dyn ; : 1-13, 2021 Mar 08. (https://doi.org/10.1080/07391102.2021.1892529) WHO COVID-19 ID: covidwho-1121008

19. Kamal Kant, Uma Ranjan Lal, Ravi Rawat, Anoop Kumar, Manik Ghosh. Genus Arisaema: A Review of Traditional Importance, Chemistry and Biological Activities. Combinatorial Chemistry & High Throughput Screening 2020 (https://doi.org/10.2174/1386207323666200416150754 )

20. Rittà, Massimo; Marengo, Arianna; Civra, Andrea; Lembo, David; Cagliero, Cecilia; Kant, Kamal; Lal, Uma Ranjan; Rubiolo, Patrizia; Ghosh, Manik*; Donalisio, Manuela. Antiviral Activity of a Arisaema tortuosum Leaf Extract and Some of its Constituents against Herpes Simplex Virus Type 2. Planta Med 2020; 86(04): 267-275 (https://doi.org/10.1055/a-1087-8303 )

21. Suddhasattya Dey, Souvik Basak, Anjan De, Shahreja Parvez, Tabassum Hossain, Achintya Saha, Manik Ghosh, Tanushree Karmakar, Simultaneous Pharmacokinetics Estimation of Nateglinide and Pioglitazone by RP-HPLC: Computational Study to Unlock the Synergism, Journal of Chromatographic Science 2020, 58(4): 309–322. (https://doi.org/10.1093/chromsci/bmz116 )

22. Suddhasattya Dey, Manik Ghosh*. Bioactivity-guided isolation of Laccaic Acid-A: A potent anti-cancer agent from Laccifer lacca (Kerr).  Indian Journal of Traditional Knowledge 2019; 18(4): 677-685. (http://nopr.niscair.res.in/handle/123456789/50640 ) ISSN: 0975-1068 (Online); 0972-5938 (Print)

23. Kamal Kant, Uma Ranjan Lal, Manik Ghosh*. Antibacterial Activity with Bacterial Growth Kinetics and GC-MS Studies on Leaf and Tuber Extracts of Arisaema tortuosum (Wall.) Schott. Indian Journal of Pharmaceutical Education and Research, 53(3[2]), S280-S287, 2019 (https://doi.org/10.5530/ijper.53.3s.98 )

24. Shruti Nayan, Chanchal Kumar Mishra, Divya Priyadarshini, Kishanta Kumar Pradhan, Manik Ghosh, Ashok Pattnaik. Wound Healing Activity of Gel Formulated Leaves Extract of Neolamarckia cadamba (Roxb) Bosser. Indian Journal of Pharmaceutical Education and Research, 53(3[2]), S416-S422, S287, 2019 (https://doi.org/10.5530/ijper.53.3s.114 )

25. Gourav Kumar, Manik Ghosh, Dev Pandey. Method development for optimized green synthesis of gold nanoparticles from Millettia pinnata and their activity in Non-small cell lung cancer cell lines. IET Nanobiotechnology, 13 (6):626-633, 2019 (https://doi.org/10.1049/iet-nbt.2018.5410 )

26. Kamal Kant, Uma Ranjan Lal, Anoop Kumar, Manik Ghosh*. A merged molecular docking, ADME-T and dynamics approaches towards the genus of Arisaema as herpes simplex virus type 1 and type 2 inhibitors.  Computational Biology and Chemistry 78 (2019) 217–226. (https://doi.org/10.1016/j.compbiolchem.2018.12.005 )

27. Suddhasattya Dey, Manik Ghosh. A LC/MS-MS Guided Isolation of Laccaic Acid-A: A Potent Antimicrobial Agent. Indian J of Pharmaceutical Education and Research. 2018;52(4 Suppl 2):S287-S295. (https://doi.org/10.5530/ijper.52.4s.109 ) 

28. Padma Charan Behera, Manik Ghosh. Evaluation of antioxidant, antimicrobial, and antiurolithiatic potential of different solvent extracts of Aerva lanata linn flowers. Pharmacognosy Magazine 2018; 14(53): 53-57. (https://doi.org/10.4103/pm.pm_60_17 )

29. Manuela Donalisio, Valeria Cagno, Andrea Civra, Davide Gibellini, Giuseppina Musumeci, Massimo Rittà, Manik Ghosh, David Lembo. The traditional use of Vachellia nilotica for sexually transmitted diseases is substantiated by the antiviral activity of its bark extract against sexually transmitted viruses. Journal of Ethnopharmacology 2018; 213: 403–408. (https://doi.org/10.1016/j.jep.2017.11.039 )

30. Suddhasattya Dey, Shreya Shah, Manik Ghosh, Neha Karki, Souvik Basak and Nanda Gopal Sahoo. A Novel, Quick Column Switching RP-HPLC Guided Metabolite Profiling of Albendazole-Praziquantel in Rat Plasma: Designing New Combination Dosage Regimen with Higher Therapeutic Window. Current Analytical Chemistry, 2018 (http://dx.doi.org/10.2174/1573411014666171206152945 )

31. Kamal Kant, Uma Ranjan Lal, Manik Ghosh*. In silico prediction and wet lab validation of Arisaema tortuosum (Wall.) schott extracts as antioxidant and anti-breast cancer source: A comparative study. Pharmacognosy Magazine 2017; 13(52): 786-790. (https://doi.org/10.4103/pm.pm_69_17 )

32. Kamal Kant, Uma Ranjan Lal, Manik Ghosh*. Computational breakthrough of natural lead hits from the genus of Arisaema against human respiratory syncytial virus. Pharmacognosy Magazine 2017; 13(52): 780-785. (https://doi.org/10.4103/pm.pm_459_16 )

33. Manik Ghosh, Andrea Civra, Massimo Rittà, Valeria Cagno, Siva Ganesh Mavuduru, Preeti Awasthi, David Lembo, Manuela Donalisio. Ficus religiosa L. bark extracts inhibit infection by herpes simplex virus type 2 in vitro. Archives of Virology 2016, 161(12): 3509-3514; (http://dx.doi.org/Archives of Virology) ISSN: 0304-8608 (Print); 1432-8798 (Online)

34. Padma Charan Behera, Bama Prasad Bag & Manik Ghosh*. Anti-urolithiatic activity of hydrogenated naphthol isolated from Aerva lanata (L.) Juss. flower extract. Indian Journal of Traditional Knowledge 2016; 15(3): 453-459. ISSN: 0975-1068 (Online); 0972-5938 (Print)

35. Valeria Cagno, Andrea Civra, Ravi Kumar, Subhankar Pradhan, Manuela Donalisio, Barij Nayan Sinha, Manik Ghosh*, David Lembo*. Ficus religiosa L. bark extracts inhibit Human Rhinovirus and Respiratory Syncytial Virus infection in vitro. Journal of Ethnopharmacology 2015, 176:252-257. (http://dx.doi.org/10.1016/j.jep.2015.10.042) ISSN: 0378-8741 (Print)

36. Chandradeep Singh, Pushpani Sharma, Trishna Bal, Manik Ghosh, Ram Dubey and Soumyajit Das. Preparation and evaluation of Radiosensitizing agent Nimorazole in topical emulgel. Der Pharmacia Lettre 2015, 7(9):132-142. (http://scholarsresearchlibrary.com/dpl-vol7-iss9/DPL-2015-7-9-132-142.pdf ) ISSN: 0975-5071

37. A. Kumar, R.K. Dubey, K. Kant, D. Sasmal, M. Ghosh, and N. Sharma. Determination of Deltamethrin in Mice Plasma and Immune Organs by Simple Reversed-Phase HPLC. Acta Chromatographica (http://dx.doi.org/10.1556/1326.2016.28.2.4 ) ISSN: 1233-2356 (Print) ISSN: 2083-5736 (Online)

38. Ramkumar Dubey; Manik Ghosh*; Barij Nayan Sinha; Venkateswari Muthukrishnan. Simultaneous Determination and Pharmacokinetics of Metolazone, Losartan and Losartan Carboxylic Acid in Rat Plasma by HPLC–ESI–MS-MS. Journal of Chromatographic Science 2015; (http://dx.doi.org/10.1093/chromsci/bmv047) ISSN: 0021-9665 (Print) ISSN: 1945-239X (Online) 

39. Soumyajit Das, Ramkumar Dubey, Subhradip Roychowdhury, Manik Ghosh*, Barij Nayan Sinha, Kishanta Kumar Pradhan, Trishna Bal, Venkateswari Muthukrishnan, Julio A. Seijas, Abhijit Pujari. A rapid and sensitive determination of hypoxic radiosensitizer agent nimorazole in rat plasma by LC-MS/MS and its application to a pharmacokinetic study. Biomedical Chromatography 2015; 29(10): 1575-1580. (http://dx.doi.org/10.1002/bmc.3461) ISSN: 0269-3879 (Print) ISSN: 1099-0801 (Online)

40. Ramkumar Dubey, Manik Ghosh*. Simultaneous Determination and Pharmacokinetic Study of Losartan, Losartan Carboxylic Acid, Ramipril, Ramiprilat, and Hydrochlorothiazide in Rat Plasma by a Liquid Chromatography/Tandem Mass Spectrometry Method. Sci. Pharm. 2015; 83(1): 107–124. (http://dx.doi.org/10.3797/scipharm.1410-15) ISSN: 0036-8709 (Print) ISSN: 2218-0532 (Online) 

41. Siva Ganesh M, Preeti Awasthi, Ajay Kumar Timiri and Manik Ghosh*. A novel approach for rationale selection of medicinal plants against viruses via molecular docking studies. The Pharmstudent 2015: 18-30. ISSN: 0379-556X (Print)/ ISSN: 2347-6001 (Online)

42. Ladli Kumari, Papiya Mitra Mazumder, Manik, UR Lal and R Dubey. High performance thin layer chromatography fingerprint profile, isolation, its antioxidant activity and spectroscopic characterization of marker compound of Murraya koenigii. Journal of Pharmacognosy and Phytochemistry 2014; 3(4): 86-92. (http://www.phytojournal.com/vol3Issue4/19.1.html) E-ISSN: 2278-4136; P-ISSN: 2349-8196

43. Aditi Paul; Trishna Bal; Ram Dubey; Manik Ghosh. A Statistical Approach Towards Development and Optimization of Conventional Immediate Release Tablet of Nimorazole by Wet Granulation Technique. Iranian Journal of Pharmaceutical Sciences 2013; 9(4): 23-38. (http://www.ijps.ir/pdf_10244_dc013890be33e6456e30a2cbd206c798.html) ISSN: 1735-2444 

44. Ramkumar Dubey, Soumyajit Das, Subhradip Roychowdhury, Kishanta K Pradhan, Manik Ghosh. Validated HPTLC Method for the Determination of Azelastine hydrochloride in Bulk Drug and Dosage Form. PHARMBIT, Jan – Jun 2013; XXVII (1): 9-11. ISSN: 0973-6204

45. Preeti Awasthi, Siva G Mavuduru, Manik Ghosh. Ayurveda: Combating Viral Diseases since Ages. PHARMBIT, Jul – Dec 2013; XXVIII (2): 25-30. ISSN: 0973-6204

46. Ratna Ghosh, Reshma Xalxo and Manik Ghosh. Estimation of Heavy Metal in Vegetables from different Market Sites of Tribal based Ranchi City through ICP-OES and to assess Health Risk. Current World Environment 2013, 8(3): 435-444. (http://dx.doi.org/10.12944/CWE.8.3.13) ISSN: 0973-4929, Online ISSN: 2320-8031

47. Manoj Goyal, Manik Ghosh, B.P. Nagori, D. Sasmal. Analgesic and anti-inflammatory studies of cyclopeptide alkaloid fraction of leaves of Ziziyphus nummularia. Saudi Journal of Biological Sciences 2013, 20 (4): 365–371. (http://dx.doi.org/10.1016/j.sjbs.2013.04.003) ISSN: 1319-562X 

48. Mukul Chandra Gope, Ratna Ghosh, Manik Ghosh, Rupali Patra. Relative Efficiencies of the Dietary Proteins of Plant and Animal Origin: A Comparative Study. PHARMBIT, Jan – Dec 2011; XXIII & XXIV (1& 2): 53-56. ISSN: 0973-6204

49. Ratna Ghosh, Reshma Xalxo, Mukul Chandra Gope, Sougata Mishra,  Bindu Kumari, Manik Ghosh. Estimation of Heavy Metals in locally available Vegetables collected from Road Side Market Sites (1-4) of different areas of Ranchi City. PHARMBIT, Jan – Dec 2011; XXIII & XXIV (1& 2): 68-73. ISSN: 0973-6204

50. Manik, B.N. Sinha and D. Sasmal. Psychopharmacological and Anticonvulsant effects of Litsea polyantha Juss. bark extract in mice: Role of serotonergic pathways. Asian Journal of Chemistry 2011, 23(1): 315-318. ISSN: 0970-7077

51. Manik Ghosh and B.N. Sinha. GC-MS Studies on the Bark Extracts of Litsea polyantha JUSS. Middle East Journal of Scientific Research 2010, 5 (6): 441-444. (http://www.idosi.org/mejsr/mejsr5(6).htm) ISSN: 1990-9233 EISSN : 1999-8147

52. Suddhasattya Dey, Y.Vikram Reddy, Bala Krishna, Sudhhir Kumar Sahoo, P.N. Murthy, Dhiraj Kumar, Juneid Alam and Manik Ghosh. Spectrophotometric Estimation of Gemifloxacin in bulk and Pharmaceutical dosage form by UV Spectrophotometry. International Journal of Chemical and Analytical Science 2010, 1(6), 130-133. (http://ijcas.info/article/download/2772/1458) ISSN: 0976-1209

53. Arjun Patra, S. Jha, P.N. Murthy, Manik, A. Sharone. Isolation and characterization of stigmast-5-en-3β-ol (β-sitosterol) from the leaves of Hygrophila spinosa T. Anders. International Journal of Pharma Sciences and Research, 2010, 1(2), 95-100. (http://www.ijpsr.info/docs/IJPSR-10-01-02-03.pdf) ISSN: 0975-9492

54. Trishna Bal, Ramadevi Pulella, Shikha Prasad, Rajni Gupta, P. N. Murthy, Manik Ghosh. Preparation and In-vitro Evaluation of Varapamil hydrochloride Microcapsules. PHARMBIT, Jul – Dec 2009; XX (2): 119-125. ISSN: 0973-6204

55. Ayushman Tiwari, Manik Ghosh, Sridhar Narayan, Pradeep Kumar and Rakesh K Sindhu. Simultaneous analysis of Paracetamol and Tramadol – Analytical method development & validation. Der Pharma Chemica, 2009, 1(2): 72-78. (http://derpharmachemica.com/second-issue/9.DPC-1_2_72-78.html) ISSN: 0975-413X

56. Manik, B. N. Sinha and S. R. Swain. Sub-chronic Toxicity Studies of the Alcoholic Extract of Litsea polyantha Juss Bark. Pharmacologyonline, May-August 2009; 2: 1106-1110. (http://www.unisa.it/download/1966_11225_1172605789_109_exN35_.Manik.pdf) ISSN: 1827-8620

57. J. Sahoo, P. N. Murthy, S. Biswal and Manik. Formulation of Sustained-Release Dosage Form of Verapamil Hydrochloride by Solid Dispersion Technique Using Eudragit RLPO or Kollidon®SR. AAPS PharmSciTech, March 2009;10(1): 27-33. (http://dx.doi.org/10.1208/s12249-008-9175-0) ISSN: 1530-9932

58. Ratna Gope and Manik “Assessment of Dietary Micronutrients in Institutionalized Geriatric” PHARMBIT, Jan-Jun 2008; XVII (1): 69-73. ISSN: 0973-6204

59. Abhimanyu Dev & Manik. “Gene Knockout” PHARMBIT, Jul – Dec 2007; XVI (2): 105-109. ISSN: 0973-6204

60. Manik. “Biostatistics Analysis Tools from Microsoft Excel” Pharmawave: The Technical Journal of Pharmacy & Health, 2007; 2/07: 71-81. 

61. Manik & B N Sinha. “Software on Inflammatory Diseases” PHARMBIT Jan – Jun 2007; XV (1); 30-38. ISSN: 0973-6204