Research @ ANTs

Investigation on the Heating Effects of Intra-Tumoral Injectable Magnetic hydrogels (IT-MG) for Cancer Hyperthermia

This study develops an injectable magnetic hydrogel (HA-SPIONs) for targeted hyperthermia, demonstrating effective temperature increases under RF radiation for potential thermal cancer therapy applications.

Biomedical Physics & Engineering Express

IOP : 10.1088/2057-1976/adaec6

Synthetic Polymers in Drug and Biotherapeutics Delivery

This chapter explores the synthesis, properties, and applications of PNIPAAm in bioimaging, drug delivery, hyperthermia, and tissue engineering, highlighting its thermo-responsive nature.

Woodhead Publishing Series in Biomaterials

Elsevier, 2025: 10.1016/B978-0-323-95233-0.00007-8

Pioneering accessibility: Development of a cost-efficient optical imaging system

This study presents a carbon quantum dots-assisted optical imaging system for rapid, low-cost tissue imaging, enabling drug discovery and disease detection through fluorescence tracking.

IEEE-Xplore, 2024

IEEE

Next-Gen Nano Biosensor Technologies to Monitor Carbapenem Resistance for Personalized Medicine

This review article highlights the growing carbapenem resistance (18-31% in India) in Enterobacteriaceae, the potential of microfluidic biosensors for detection, and adoption challenges in healthcare.

Indian Journal of Microbiology, 2024 

Springer

Fusion of Exosomes and Nanotechnology: Cutting-Edge Cancer Theranostics

We have highlighted the integration of exosomes and nanotechnology which is a cutting-edge approach in precision oncology.

ACS Applied Nanomaterials, 2024 

ACS

Performance Evaluation of Carbon Quantum Dots Impregnated Glass Ionomer Cement to avoid Peri-implant disease

Biomedical Materials, 2024 

IOP Publishers

Single Molecule Imaging Using State-of-the-Art Microscopy Techniques 

CRC Press,2023 

Book Name: Single Biomolecule Detection and Analysis

SERS Analysis for Single-Molecule Detection of Disease Biomarkers

CRC Press,2023 

Book Name: Single Biomolecule Detection and Analysis

SATU Presidential Collaborative Research Work with Dr. Noraini Ahamed, University of Malaya, Malaysia. 

Develop Nanoemulsion for skin treatment

Completion of Special Issue in Materials Today Chemistry

Edited by 

• Dr. Yogendra Kumar

• Dr. Niraj Kumar Jha

• Dr. Ashwin Kumar N

• Dr. Piyush Gupta

Just Accepted Review Article in Nanomedicine, Future Science - IF : 6.07. 

Advances and opportunities of nano imaging agents for the diagnosis of inflammatory lung diseases

• Inflammatory Lung Disorder Imaging

• Imaging agents for Inflammation 

Just Accepted Review Article in Micromachines, MDPI, IF: 3.54. 

Perspectives and opportunities in Targeted Immuno-Nanomaterials in Cancer

• Review focuses on the nanomaterial-based strategies that have shown promise in identifying various immunological markers in the tumor microenvironment (TME) for cancer diagnosis and therapy.

• Perspective on artificial intelligence and lab-on-a-chip tools to facilitate ICs-based nano theranostics toward cancer immunotherapy.

Journal Link:

https://www.journals.elsevier.com/materials-today-chemistry/call-for-papers/special-issue-on-smart-nanomaterials-for-cancer-theranostics

Special Issue invites : Research and Review articles

• Cancer Theranostics

• Smart Nanomaterials 

• Drug Delivery 

• Tissue Engineering

• Biomarkers Detection and Diagnosis

• Bioimaging

BIOSENSORS FOR EARLY DIAGNOSIS OF CANCER AND IMMUNE CHECKPOINTS BLOCKADE THERAPY MONITORING FROM LIQUID BIOPSY

• Cancer biomarkers detection from a small volume of blood is relatively fast compared to the gold standard of tissue biopsies. 

• Traditional immuno-histochemistry (IHC) detection required tissue samples obtained from invasive procedures and specific expertise as well as sophisticated instruments.

• Emerging interest in understanding the immune checkpoints facilitate the rapid detection of cancer prognosis from the liquid biopsy. 

APTAMERIC NANOBIOSENSORS FOR THE DIAGNOSIS OF COVID-19- AN UPDATE

• Aptameric nanobiosensors is an affinity-based nanosensors interfaced with aptamers.

• It is a rapid and sensitive diagnostic platform for the detection of SARS-CoV-2.

• Detection limit of these apta-nanobiosensors vary from pM to fM concentrations.

• Careful selection of aptamers and signal transducers is critical for better results.

IMPACT OF GOLD-DECORATED TANTALUM OXIDE (TAOX-AU) NANO-PROBES FOR LOW ENERGY CANCER DIAGNOSTIC AGENT

• Novel synthesis of Gold-decorated Tantalum oxide nanoparticles (TaOx-Au NPs) as multifunctional nanoprobe.

• TaOx-Au NPs are characterized revels the formation of gold over TaOx NPs.

• TaOx-Au exhibits high X-ray attenuation when exposed to X-rays, making it suitable for cancer diagnostics.

INFLUENCE OF EUROPIUM (EU) DOPED TANTALUM OXIDE NANOPARTICLES (TAOX NPS): A POTENTIAL CONTRAST AGENT

• Novel one-step synthesis of Europium (Eu) doped Tantalum Oxide (TaOx) nanoparticles.

• Physicochemical properties are characterized for doped and undoped nanoparticles.

• 10% of Eu: TaOx NPs with UV rays showed intense red emission.

• TaOx and Eu: TaOx NPs irradiated with X-rays showed reddish orange and blue emission.

• Proposed mechanism of emission is due to energy transfer from host materials and direct radiation effect of Europium.

NANOPARTICLES FOR CANCER HYPERTHERMIA

• Interaction of Gold nanoparticles (AuNPs) and gold nanoclusters (AuNCs) with radiofrequency (RF) field for hyperthermia treatment is ambiguous and needs further investigation. 

• A systematic study of the absorption of capacitive RF field by AuNPs and AuNCs dispersed in phosphate-buffered saline (PBS) is reported here in tissue mimicking phantom. 

• Phantom heating was carried out using 27 MHz short-wave diathermy equipment at 200 and 400 W for control and colloidal gold solutions. 

• It is concluded that AuNPs and AuNCs do not enhance the absorption of RF-capacitive field and power absorption observed in the biological medium is due to the ions present in the medium.

REVIEW ARTICLE ON COVID-19

• Emphasizing the huge demand for affordable point of care diagnostic tools to control the global COVID-19 pandemic.

• Highlighting the recent advances in the development of PoC based optical and electrochemical biosensors.

• Reviewed the application of wearables and smart nanobiosensors for real time monitoring of COVID-19.

BOOK CHAPTER IN MICROFLUIDICS

• Book chapter describes the synthesis of different metal nanoparticles using microfluidic devices and their potential biomedical applications. 

• Multiphase microfluidics, Continuous- (laminar) and segmented-flow types of microfluidic processes have been used to synthesize metallic nanoparticles, with their unique physical and chemical characteristics and controlled nano-structure. 

• Chapter elaborates the future challenges of nanoparticle preparation using microfluidic devices and their applications, advantages, and limitations. 

BOOK CHAPTER IN MICROFLUIDICS

• Book chapter describes the synthesis of different metal nanoparticles using microfluidic devices and their potential biomedical applications. 

• Multiphase microfluidics, Continuous- (laminar) and segmented-flow types of microfluidic processes have been used to synthesize metallic nanoparticles, with their unique physical and chemical characteristics and controlled nano-structure. 

• Chapter elaborates the future challenges of nanoparticle preparation using microfluidic devices and their applications, advantages, and limitations.