I am an Associate Professor in the Center for Public Health Genomics at the University of Virginia.

My research lies in the areas of statistical genetics and genetic epidemiology with an emphasis on 1) integrative analysis leveraging multi-omics data to interpret results of genome-wide association studies, 2) genetic analysis in multi-ethnic and admixed populations, and 3) translational research efforts bridging mouse and human studies.

I am actively involved in genome-wide association analysis of pulmonary and cardiovascular phenotypes performed through the Multi-Ethnic Study of Atherosclerosis (MESA). We are working actively on integrative 'omics combining genomic, transcriptomic, proteomic and other high-dimensional data sets from the NHLBI Trans-omics for Precision Medicine (TOPMed) project, the Genotype-Tissue Expression (GTEx) project, and others to identify causal genes and pathways influencing diseases of interest. We are also performing other types of post-GWAS research, including gene-environment interaction studies, fine mapping studies, and candidate gene investigations with collaborators who are experts in animal models and in vitro studies of more focused genetic pathways.