Publication

2021

Jian Zeng, Angli Xue, Longda Jiang, Luke R Lloyd-Jones, Yang Wu, Huanwei Wang, Zhili Zheng, Loic Yengo, Kathryn E Kemper, Naomi R Wray, Peter M Visscher, Jian Yang. Widespread signatures of natural selection across human complex traits and functional genomic categories. Nature Communications. 12.1 (2021): 1-12. [View Article]

Angli Xue, Longda Jiang, Zhihong Zhu, Naomi R. Wray, Peter M. Visscher, Jian Zeng, Jian Yang. Genome-wide analyses of behavioural traits biased by misreports and longitudinal changes. Genome-wide analyses of behavioural traits are subject to bias by misreports and longitudinal changes. Nature Communications. 12, 6450. 2021. [View Article]

Xiwei Sun, Angli Xue, Ting Qi, Dan Chen, Dandan Shi, Yang Wu, Zhili Zheng, Jian Zeng and Jian Yang. Tumor mutational burden is polygenic and genetically associated with complex traits and diseases. Cancer Research. 81 (5), 1230-1239. 2021. [View Article]

Christelle Adolphe#, Angli Xue# (co-first author), Atefeh Taherian Fard, Laura A. Genovesi, Jian Yang, Brandon Wainwright. Genetic and functional interaction network analysis reveal global enrichment of regulatory T Cell genes influence basal cell carcinoma susceptibility. Genome Medicine. 13 (1), 1-12. 2021. [View Article] [GWAS catalog]

Haoyang Zhang, Xuehao Xiu, Angli Xue, Yuedong Yang, Yuanhao Yang, Huiying Zhao. Mendelian randomization study reveals a population-specific putative causal effect of type 2 diabetes in risk of cataract. International Journal of Epidemiology. 2021 [View Article]

2020

Joana Revez, Tian Lin, Zhen Qiao, Angli Xue, Yan Holtz, Zhihong Zhu, Jian Zeng, Huanwei Wang, Julia Sidorenko, Kathryn Kemper, Anna Vinkhuyzen, Julanne Frater, Darryl Eyles, Thomas Burne, Brittany Mitchell, Nicholas Martin, Gu Zhu, Peter Visscher, Jian Yang, Naomi Wray, John McGrath. Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration. Nature Communications. 11 (1), 1-12. 2020. [View Article]

2019

Mike Nalls, Cornelis Blauwendraat , Costanza Vallerga , Karl Heilbron , Sara Bandres-Ciga , Diana Chang , Manuela Tan , Demis Kia , Alastair Noyce , Angli Xue , Jose Bras , Emily Young , Ranier von Coelln , Javier Simon-Sanchez , Claudia Schulte , Manu Sharma , Lynne Krohn , Lasse Pihlstrom , Ari Siitonen , Hirotaka Iwaki , Hampton Leonard , Faraz Faghri , Raphael Gibbs , Dena Hernandez , Sonja Scholz , Juan Botia , Maria Martinez , Jean-Chrstophe Corvol , Suzanne Lesage , Joseph Jankovic , Lisa Shulman , The 23andMe Research Team , System Genomics of Parkinson's Disease (SGPD) Consortium, Margaret Sutherland , Pentti Tienari , Kari Majamaa1 , Mathias Toft , Alexis Brice , Jian Yang , Ziv Gan-Or , Thomas Gasser , Peter Heutink , Joshua Shulman , Nicholas Wood , David Hinds , John Hardy , Huw Morris , Jacob Gratten , Peter Visscher , Robert Graham , Andrew Singleton for the International Parkinson’s Disease Genomics Consortium. Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. The Lancet Neurology. 18 (12), 1091-1102. 2020. [View Article]

Huanwei Wang, Futao Zhang, Jian Zeng, Yang Wu, Kathryn E Kemper, Angli Xue, Min Zhang, Joseph E Powell, Michael E Goddard, Naomi R Wray, Peter M Visscher, Allan F McRae, Jian Yang. Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Science advances. 5 (8), eaaw3538. 2019. [View Article]

Alastair Noyce, Sara Bandres Ciga, Jonggeol Kim, Karl Heilbron, Gibran Hemani, Angli Xue, Deborah A Lawlor, George Davey Smith, Raquel Duran, Ziv Gan-Or, Cornelis Blauwendraat, Raphael Gibbs, David Hinds, Jian Yang, Peter M Visscher, Jack Cuzick, Huw Morris, John Hardy, Nicholas Wood, Mike A Nalls, Andrew Singleton. The Parkinson’s Disease Mendelian Randomization Research Portal. Movement disorders. 34.12: 1864-1872. 2019. [View article]

Regina H. Reynolds, Juan Botía, Mike A. Nalls, International Parkinson’s Disease Genomics Consortium (IPDGC), System Genomics of Parkinson’s Disease (SGPD), John Hardy, Sarah A. Gagliano Taliun & Mina Ryten. Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability. NPJ Parkinson's disease 5.1 (2019): 6. [View article]

2018

Enda M Byrne, Manuel Ferreira, Angli Xue, Sara Lindström, Xia Jiang, Douglas Easton, Naomi R Wray, Georgia Chenevix-Trench. Is schizophrenia a risk factor for breast cancer? – Evidence from genetic data. Schizophrenia Bulletin. 45.6 (2019): 1251-1256. [View Article]

Angli Xue#, Yang Wu#, Zhihong Zhu, Futao Zhang, Kathryn E Kemper, Zhili Zheng, Loic Yengo, Luke R. Lloyd-Jones, Julia Sidorenko, Yeda Wu, eQTLGen Consortium, Allan F McRae, Peter M Visscher, Jian Zeng*, Jian Yang*. Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. Nature Communications. 9.1 (2018): 2941. [View Article] [GWAS catalog]

Jian Zeng, Ronald de Vlaming, Yang Wu, Matthew R Robinson, Luke Lloyd-Jones, Loic Yengo, Chloe Yap, Angli Xue, Julia Sidorenko, Allan F McRae, Joseph E Powell, Grant W Montgomery, Andres Metspalu, Tonu Esko, Greg Gibson, Naomi R Wray, Peter M Visscher, Jian Yang*. Signatures of negative selection in the genetic architecture of human complex traits. Nature Genetics 50.5 (2018): 746. [View Article]

Ting Qi, Yang Wu, Jian Zeng, Futao Zhang, Angli Xue, Longda Jiang, Zhihong Zhu, Kathryn Kemper, Loic Yengo, Zhili Zheng, eQTLGen Consortium, Riccardo E Marioni, Grant W Montgomery, Ian J Deary, Naomi R Wray, Peter M Visscher, Allan F McRae, Jian Yang*. Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. Nature Communications. 9 (2018). [View Article]

2017

Angli Xue, Hongcheng Wang, Jun Zhu. Dissecting genetic architecture of complex trait using multi-omics information: A case of association mapping for startle response in Drosophila melanogaster. Scientific Reports. 7, 2017. [View Article]

Yongjun Mei#, Jiwen Yu#, Angli Xue# (Co-first author), Shuli Fan, Meizhen Song, Chaoyou Pang, Wenfeng Pei, Shuxun Yu, Jun Zhu*. Dissecting Genetic Network of Fruit Branch Traits in Upland Cotton by Association Mapping Using SSR Markers. PloS one, 2017, 12(1), e0162815. [View Article]

Before 2017

Yongjun Mei#, Jiwen Yu#, Angli Xue# (Co-first author), Shuli Fan, Meizhen Song, Chaoyou Pang, Wenfeng Pei, Shuxun Yu, Jun Zhu*. Association mapping of genetic network for plant morphological traits in cotton. Journal of Zhejiang University (Agric. & Life Sci.). 2015, 42(2), 127-136. [View Article]

Jiasheng Wang, Ke Ding, Yujie Chen, Lifeng Zhang, Zukai Liu, Angli Xue, Wenjia Gu, Xiaoyue Yang, Xihan Li, Jin Huang, Congcong Xing, Yunlong Cao, Ming Chen*. Detection of Thrombin with an Aptamer-based Macromolecule Biosensor Using Bacterial Ghost System. ACS Synth. Biol., 2014, 3 (12), 963–965. [View Article]