The Biology of Adaptation and Resilience
How does life adapt, preserve function, and recover?
I study the molecular programs that enable living systems to withstand physiological challenges and recover from stress. My research brings together brain biology and exceptional adaptive states to understand how resilience works, and how it might be enhanced.
THE CENTRAL QUESTION
What determines whether living systems adapt, recover, or develop disease?
Some physiological challenges lead to lasting damage. Others trigger protective responses that preserve function and enable recovery. Understanding what drives these different trajectories could reveal new approaches to protecting the brain and promoting health.
My research examines how living systems enter adaptive states, sustain protection, and return to function, connecting molecular mechanisms to outcomes over time.
Discover the mechanisms. Understand the transitions. Enhance resilience.
SCIENTIFIC FOUNDATION
My research builds on a foundation in microglial biology, neuroimmunology, Alzheimer’s disease, brain aging, and molecular biomarkers. Together, these fields shape how I investigate the cellular responses and molecular trajectories that underlie adaptation, resilience, and vulnerability to disease.
Microglia & Neuroimmunology
How microglial signaling and functional states shape responses to stress and pathology.
Aging & Molecular Profiling
How cellular and systemic molecular changes relate to brain aging and disease.
Longitudinal Biomarkers
How molecular measurements over time reveal trajectories of brain health and disease.