Research

We design and synthesize molecular photoswitches that respond selectively to visible light, enabling reversible and precise control over molecular structure and function. These switches are tailored to operate under biologically benign wavelengths, overcoming the limitations of UV-based systems. Our efforts focus on tuning isomerization behavior, thermal stability, and spectral responsiveness to create versatile building blocks for smart molecular systems. 

Photopharmacology

Our lab explores light-activated therapeutics, where drug activity can be modulated with spatiotemporal precision using photoswitchable/photocaging scaffolds. By integrating photoswitches into bioactive molecules, we aim to achieve targeted activation, reduced side effects, and externally controllable therapeutic interventions. This approach opens new avenues for precision medicine, enabling dynamic control over drug–target interactions in response to light.

Photoregulation of Biological Activity

We harness molecular photoswitches to modulate biological activity with light, allowing precise control over protein function, cellular processes, and biochemical pathways. This strategy provides a powerful tool for probing complex biological systems with high temporal and spatial resolution. Applications include the regulation of motor proteins, enzymatic activity, and cellular signaling using non-invasive optical inputs.

Smart Materials