Publications

Peer-reviewed publications

48) Edwards, L., Thomas, K.R., Weigand, A.J., Edmonds, E.C., Clark, A.L., Brenner, E.K., Banks, S.J., Gilbert, P.E., Nation, D.A., Delano-Wood, L., Bondi, M.W., & Bangen, K.J. (2024). Pulse Pressure and APOE e4 Dose Interact to Affect Cerebral Blood Flow in Older Adults Without Dementia. Cerebral Circulation – Cognition and Behavior, 6, 100206. 

47) Thomas, K.R., Clark, A.L., Weigand, A.J., Edwards, L., Durazo, A.A., Membreno, R., Luu, B., Rantins, P. Ly, M.T., Rotblatt, L.J., Bangen, K.J., & Jak, A.J. (2024). Cognition and Amyloid-beta in Older Veterans: Characterization and Longitudinal Outcomes of Data-derived Phenotypes. Journal of Alzheimer’s Disease. 

46) Weigand, A.J., Ortiz, G., Walker, K.S., Galasko, D.R., Bondi, M.W., & Thomas, K.R. (2023). APOE Differentially Moderates Cerebrospinal Fluid and Plasma Phosphorylated Tau181 Associations with Multi-domain Cognition. Neurobiology of Aging, 125, 1-8. 

45) Durazo, A.A., Weigand, A.J., Bangen, K.J., Membreno, R., Mudaliar, S., & Thomas, K.R. (In press, 2023). Type 2 Diabetes Moderates the Association Between Amyloid and 1-year Change in Everyday Functioning in Older Veterans. Journal of Alzheimer’s Disease. 

44) Bayram, E., Weigand, A.J., & Flatt, J.D. (2023). Perceived Discrimination in Healthcare for LGBTQIA+ People Living with Parkinson’s Disease. Journal of Gerontology: Psychological Sciences and Social Sciences, 78(9), 1459-1465. 

43) Brenner, E.K., Weigand, A.J., Edwards, L., Thomas, K.R., Edmonds, E.C., Bondi, M.W., & Bangen, K.J. (2023). Brain Derived Neurotrophic Factor Interacts with White Matter Hyperintensities to Influence Processing Speed and Hippocampal Volume in Older Adults. Journal of Alzheimer’s Disease, 93(1), 141-149. 

42) Edwards, L., Thomas, K.R., Weigand, A.J., Edmonds, E.C., Clark, A.L., Walker, K.S., Brenner, E.K., Nation, D.A., Bondi, M.W., & Bangen, K.J. (2023). White Matter Hyperintensity Volume and Amyloid-PET Synergistically Impact Executive Dysfunction and Memory Independently of Tau-PET in Older Adults Without Dementia. Journal of Alzheimer’s Disease, 94(2), 695-707. 

41) Rantins, P., Ly, M., Clark, A.L., Weigand, A.J., Alshaheri, A., Merritt, V.C., Bangen, K.J., & Thomas, K.R. (2023). TBI Severity Moderates the Association between Subjective and Objective Attention in Older Veteran. Journal of Head Trauma and Rehabilitation, 10.1097. 

40) Ehrenberg, A.J., Kelberman, M.A., Liu, K.Y., Dahl, M.J., Weinshenker, D., Falgas, N., …Weigand, A.J., … & Grinberg, L.T. (2023). Priorities for Research on Neuromodulatory Subcortical Systems in Alzheimer’s Disease: Position Paper from the NSS PIA of ISTAART. Alzheimer’s & Dementia. 

39) Weigand, A.J., Edwards, L., Thomas, K.R., Bangen, K.B., & Bondi, M.W. (2022). Comprehensive characterization of elevated tau PET biomarker signal in the absence of amyloid-beta. Brain Communications, 4(6), fcac272.

38) Weigand, A.J., Macomber, A.J., Walker, K.S., Edwards, L., Thomas, K.R., Bangen, K.J., Nation, D.A., & Bondi, M.W. (2022). Interactive effects of pulse pressure and tau imaging on longitudinal cognition. Journal of Alzheimer's Disease, 89(2), 633-640.

37) Weigand, A.J., Hamlin, A., Breton, J., & Clark, A.C. (2022). Cerebral Blood Flow, Tau Imaging, and Memory Associations in Cognitively Unimpaired Older Adults. Cerebral Circulation – Cognition and Behavior, 3, 100153.

36) Weigand, A.J., Maass, A., Eglit, G.M.L, & Bondi, M.W. (2022). What’s the cut-point? A systematic investigation of tau PET thresholding methods. Alzheimer's Research & Therapy, 14(1), 49.

35) Clark, A.L., Weigand, A.J., Clay, O.J., Marsiske, M., Owens, J.H., Fiala, J., Crowe, M., & Thomas, K.R. (2022). Associations Between Social Determinants of Health and 10-year Change in Everyday Functioning Within Black and White Older Adults Enrolled in ACTIVE. Alzheimer's & Dementia: DADM, 14(1), e12385.

34) Thomas, K.R, Weigand, A.J., Edward, L.C., Edmonds, E.C., Bangen, K.J., Ortiz, G., Walker, K.S., & Bondi, M.W. (2022). Tau Levels are Higher in Objective Subtle Cognitive Decline but Not Subjective Memory Complaint. Alzheimer’s Research & Therapy, 14, 114.

33) Thomas, K.R., Bangen, K.J., Weigand, A.J., Ortiz, G., Walker, K.S., Salmon, D.P., Bondi, M.W., & Edmonds, E.C. (2022). Cognitive Heterogeneity and Risk of Progression in Data-Driven Subtle Cognitive Decline Phenotypes. Journal of Alzheimer’s Disease, 90(1), 323-331.

32) Brenner, E.K., Thomas, K.R., Weigand, A.J., Edward, L., Edmonds, E.C., Bondi, M.W., & Bangen, K.J. (2022). Cognitive Reserve Moderates the Association Between Cerebral Blood Flow and Language Performance in Older Adults with Mild Cognitive Impairment. Alzheimer’s & Dementia: Clinical Manifestations, 18(S7), e062810. 

31) Thomas, K.R., Weigand, A.J., Cota, I.H., Edmonds, E.C., Wierenga, C.E., Bondi, M.W., & Galasko, D.R. (2022). Intrusion errors moderate the relationship between blood glucose and regional cerebral blood flow in cognitively unimpaired older adults. Brain Imaging and Behavior, 16(1), 219-227.

30) Solders, S.K., Galinsky, V.L., Clark, A.L., Sorg, S.F., Weigand, A.J., Bondi, M.W., & Frank, L.R. (2022). Diffusion Magnetic Resonance Imaging Tractography of the Locus Coeruleus-Transentorhinal Cortex Connections Using Geometric-Optics based Entropy Spectrum Pathways. Magnetic Resonance Imaging, 87(4), 1816-1831.

29) Weigand, A.J., Thomas, K.R., Bangen, K.J., Eglit, G.M.L., Delano-Wood, L., Gilbert, P.E., Brickman, A.M. & Bondi, M.W. (2021) APOE  Interacts with Tau PET to Influence Memory Performance Independently of Amyloid PET.  Alzheimer's & Dementia, 17(1), 61-69.

28) Clark, A.C., Weigand, A.J., Bangen, K.J., Thomas, K.R., Eglit, G.M.L, Bondi, M.W., & Delano-Wood, L. (2021). Higher cerebrospinal fluid tau is associated with history of traumatic brain injury and reduced processing speed in Vietnam-era veterans: A Department of Defense Alzheimer's Disease Neuroimaging Initiative (DOD-ADNI) study. Alzheimer’s & Dementia: DADM, 13(1), e12239. 

27) Clark, A.L., Weigand, A.J., Bangen, K.J., Merritt, V., Bondi, M.W., & Delano-Wood, L.  (2021). Repetitive mTBI is Associated with Age-Related Reductions in Cerebral Blood Flow but Not Cortical Thickness. Journal of Cerebral Blood Flow & Metabolism, 41(2), 431-444.

26) Clark, A.C., Weigand, A.J., Thomas, K.R., Solders, S.K., Delano-Wood, L., Bondi, M.W., Bernier, R.A., Sundermann, E.S., Banks, S.J., & Bangen, K.J. (2021). Elevated Inflammatory Markers and Arterial Stiffening Exacerbate Tau but not Amyloid Pathology in Older Adults with MCI. Journal of Alzheimer’s Disease, 80(4), 1451-1463.

25) Bangen, K.J., Thomas, K.R. Weigand, A.J., Edmonds, E.C., Clark, A.L., Solders, S., Delano-Wood, L., Galasko, D.R., & Bondi, M.W. (2021). Elevated Plasma Neurofilament Light is Associated with Objectively-Defined Subtle Cognitive Difficulties and Predicts Future Cognitive and Functional Decline.  Alzheimer's & Dementia, 17(10), 1756-1762.

24) Werhane, M.L., Thomas, K.R., Bangen, K.J., Weigand, A.J., Edmonds, E.C., Nation, D.A., Sundermann, E.E., Bondi, M.W., & Delano-Wood, L (2021). Arterial Stiffening Moderates the Relationship Between Type-2 Diabetes Mellitus and White Matter Hyperintensity Burden in Older Adults with Mild Cognitive Impairment. Frontiers in Aging Neuroscience, 13, 716638.

23) Thomas, K.R., Bangen, K.J., Edmonds, E.C., Weigand, A.J., Walker, K.S., Bondi, M.W., & Galasko, D.R. (2021). Objective Subtle Cognitive Decline and Plasma Phosphorylated Tau181: Early Markers of Alzheimer’s Disease-Related Declines. Alzheimer’s & Dementia: DADM, 13(1), e12238. 

22) Graves, L.V., Edmonds, E.C., Thomas, K.R., Weigand, A.J., Cooper, S., Stickel, A.M., Zlater, Z.Z., & Bondi, M.W. (2021). Diagnostic Accuracy and Differential Associations Between Ratings of Functioning and Neuropsychological Performance in non-Hispanic Black and White Older Adults. The Clinical Neuropsychologist, 36(2), 287-310. 

21) Sundermann, E.E., Thomas, K.R., Bangen, K.J., Weigand, A.J., Eppig, J.S., Edmonds, E.C., Wong, C.G., Bondi, M.W., Delano-Wood, L. for the Alzheimer’s Disease Neuroimaging Initiative (2021). Prediabetes is associated with brain hypometabolism and cognitive decline in a sex-dependent manner: A longitudinal study of nondemented older adults within the Alzheimer’s Disease Neuroimaging Initiative. Frontiers in Neurology, 12, 551975. 

20) Bangen, K.J., Thomas, K.R., Sanchez, D.L., Edmonds, E.C., Weigand, A.J., Delano-Wood, L., & Bondi, M.W. (2021). Entorhinal Perfusion Predicts Future Memory Decline, Neurodegeneration, and White Matter Hyperintensity Progression in Older Adults. Journal of Alzheimer’s Disease, 81(4), 1711-1725. 

19) Bangen, K.J., Delano-Wood, L., Clark, A.L., Evangelista, N.D., Hoffman, S.N., Sorg, S.F., Holmqvist, S., Osuna, J., Weigand, A.J., Jak, A.J., Bondi, M.W., & Lamar, M. (2021). Decreased Myelin Content of the Fornix Predicts Poorer Memory Performance Beyond Vascular Risk, Hippocampal Volume, and Fractional Anisotropy in Nondemented Older Adults. Brain Imaging & Behavior, 15, 2563-2571.

18) Weigand, A.J., Bangen, K.J., Thomas, K.R., Delano-Wood, L., Gilbert, P.E., Brickman, A.M., & Bondi, M.W. (2020). Is Tau in the Absence of Amyloid on the Alzheimer’s Continuum?: A Study of Discordant PET Positivity. Brain Communications, 2(1), fcz046. 

17) Weigand, A.J., Bondi, M.W., Thomas, K.R., Campbell, N.L., Galasko, D.G., Salmon, D.P, Sewell, D.D., Brewer, J.B., Feldman, H.H., & Delano-Wood, L. (2020). Association of anticholinergic medication and AD biomarkers with incidence of MCI among cognitively normal older adults. Neurology.

16) Eglit, G.M.L., Weigand, A.J., Nation, D.A., Bondi, M.W., & Bangen, K.J. (2020). Hypertension and Alzheimer’s disease: Indirect Effects Through Circle of Willis Atherosclerosis. Brain Communications, 2(2), fcaa114. 

15) Edmonds, E.C., Weigand, A.J., Hatton, S.N., Marshall, A., Thomas, K.R., Eppig, J., Ayala, D.A., Bondi, M. W., & McDonald, C.R. (2020). Patterns of Longitudinal Cortical Atrophy Over 3 Years in Empirically Derived MCI Subtypes. Neurology, 94(24), e2532-32544.

14) Thomas, K.R., Bangen, K.J., Weigand, A.J., Edmonds, E.C., Sundermann, E., Wong, C.G., Eppig, J.S., Werhane, M.L., Delano-Wood, L., & Bondi, M.W. (2020). Type 2 Diabetes Interacts with Alzheimer's Disease Risk Factors to Predict Functional Decline. Alzheimer's Disease & Associated Disorders, 34(1), 10-17.

13) Campbell, M.C., Myers, P.S., Weigand, A.J., Cairns, N.J., Jackson, J.J., Lessov-Schlaggar, C.N., & Perlmutter, J.S. (2020). Parkinson Disease Clinical Subtypes: Key Features & Clinical Milestones. Annals of Clinical and Translational Neurology, 7(8), 1272-1283.

12) Thomas, K.R., Bangen, K.J., Weigand, A.J., Edmonds, E.C., Wong, C.G., Cooper, S., Delano-Wood, L., & Bondi, M.W. (2020). Subtle Cognitive Decline Predicts Future Amyloid Accumulation and Neurodegeneration. Neurology, 94(4), e397-e406.

11) Bangen, K.J., Thomas, K.R., Weigand, A.J., Sanchez, D., Delano-Wood, L., Edmonds, E.C.,  Carmichael, O.T., Schwarz, C.G., Brickman, A.M., & Bondi, M.W. (2020). Regional White Matter Hyperintensity Volume Distinguishes among Mild Cognitive Impairment Subtypes and Predicts Declines in Daily Functioning. Neurobiology of Aging, 86, 134-132.

10) Thomas K.R., Osuna J.R., Weigand, A.J., Edmonds, E.C., Clark, A.L., Holmqvist, S., Cota, I., Wierenga, C.W., Bondi, M.W., & Bangen, K.J. (2020). Regional Hyperperfusion in Older Adults with Objectively-Defined Subtle Cognitive Decline.  Journal of Cerebral Blood Flow & Metabolism, 41(5), 1001-1012.

9) Graves, L.G., Edmonds, E.C., Thomas, K.R., Weigand, A.J., Cooper, S., & Bondi, M.W. (2020). Evidence for the Utility of Actuarial Neuropsychological Criteria Across the Continuum of Normal Aging, Mild Cognitive Impairment, and Dementia. Journal of Alzheimer's Disease, 78(1), 371–386. 

8) Bangen, K.J., Weigand, A.J., Delano-Wood, L., Thomas, K.R., Eppig, J., Werhane, M.L., Edmonds, E.C., & Bondi, M.W. (2019). Cognitive Dispersion as a Sensitive Marker for Early Neurodegenerative Changes and Functional Decline in Non-demented Older Adults. Neuropsychology, 33(5), 599-608.

7) Thomas, K.R., Eppig, J.S., Weigand, A.J., Edmonds, E.C., Wong, C.G., Jak, A.J., Delano-Wood, L., Galasko, D.R., Salmon, D.P., Bondi, M.W. (2019). Artificially Low MCI to Normal Reversion Rate in the Alzheimer’s Disease Neuroimaging Initiative. Alzheimer's & Dementia, 15(4), 561-569.

6) Thomas, K.R., Edmonds, E.C., Eppig, J.S., Wong, C.G., Weigand, A.J., Bangen, K.J., Jak, A.J., Delano-Wood, L., Galasko, D.R., Salmon, D.P., Edland, S.D., & Bondi, M.W. (2019). MCI-to-normal Reversion Using  Neuropsychological Criteria in the Alzheimer’s Disease Neuroimaging Initiative. Alzheimer's & Dementia, 15(10), 1322-1332.

5) Edmonds, E.C., McDonald, C., Marshall, A., Thomas, K.R., Eppig, J., Weigand, A.J., Delano-Wood, L., Galasko, D.R., Salmon, D.P., Bondi, M.W. (2019). Early vs. Late MCI: Improved Staging of MCI Using a Neuropsychological Approach. Alzheimer's & Dementia, 15(5), 699-708.

4) Edmonds, E.C., Weigand, A.J., Thomas, K.R., Eppig, J., Delano-Wood, L., Galasko, D.R., Salmon, D.P., & Bondi, M.W. (2018). Increasing Inaccuracy of Self-Reported Cognitive Complaints over 24 Months in Empirically-Derived Subtypes of Mild Cognitive Impairment. Journal of the International Neuropsychological Society, 24, 842-853.

3) Bangen, K.J., Werhane, M.L., Weigand, A.J., Edmonds, E.C., Delano-Wood, L., Thomas, K.R., Nation, D.A., Evangelista, N.D., Clark, A.L., Liu, T.T., Bondi, M.W. (2018). Regional Cerebral Blood Flow Changes and Neuropsychological Function in Nondemented Older Adults with Diabetes. Frontiers Aging Neuroscience, 10, 270.

2) Wong, C.G., Thomas, K.R., Edmonds, E.C., Weigand, A.J., Bangen, K.J., Eppig, J.S., Jak, A.J., Devine, S.A., Delano-Wood, L., Libon, D.J., Edland, S.D., Au, R., & Bondi, M.W. (2018). Neuropsychological Criteria for Mild Cognitive Impairment in the Framingham Heart Study’s Old-Old. Dementia and Geriatric Cognitive Disorders, 46, 253-265.

1) Aschenbrenner, A. J., Balota, D. A., Weigand, A. J., Scaltritti, M., & Besner, D. (2017). The First Letter Position Effect in Visual Word Recognition: The Role of Spatial Attention. Journal of Experimental Psychology: Human Perception and Performance, 43(4), 700-718.

Publications under review

5) Weigand, A.J., Thomas, K.R., Edwards, L., & Bondi, M.W. (Under review). Longitudinal Cognitive Change in Older Adults with Elevated Tau PET Signal in the Absence of Amyloid.

4) Hamlin, A.M., Weigand, A.J., Clay, O.J., Marsiske, M., Wallace, G., Dadson, D., Thomas, K.R., & Clark, A.L. (Under review). The Independent and Interactive Effects of Economic Stability and Healthcare Access on 10-year Cognitive Trajectories in Black/African American and White Older Adults.

3) Luu, B., Bangen, K.J., Clark, A.L., Weigand, A.J., Rantins, P., Garcia, M.E., Urias, U., Merritt, V.C., & Thomas, K.R. (Under review). Impact of PTSD on the Associations between Subjective Cognitive Decline and Alzheimer’s Disease Pathology in Older Veterans.

2) Gonzalez, A.I., Edwards, L.C., Thomas, K.R., Weigand, A.J., Bordyug, M., Brenner, E.K., Urias, U.A., & Bangen, K.J. (Under review). GAP-43 is Associated with Faster Functional Decline among Amyloid Positive Individuals with Objectively-defined Subtle Cognitive Decline and Mild Cognitive Impairment.

1) Garcia, M.E., Rantins, P., Durazo, A.A., Urias, U., Weigand, A.J., Bangen, K.J., Bondi, M.W., Jak, A.J., & Thomas, K.R. (Under review). Associations of Post-traumatic Stress Disorder and Objective Subtle Cognitive Difficulties in Cognitively Unimpaired Older Veterans.

Peer-reviewed book chapters

2) Thomas, K.R., Edmonds, E.C., Eppig, J.S., Wong, C.G., Cooper, S., Weigand, A.J., Bondi, M.W. (In press). Mild Cognitive Impairment and Preclinical Alzheimer’s Disease. In R.W. Parks, R.F. Zec, M.W. Bondi & A.L. Jefferson (Eds.), Neuropsychology of Alzheimer's Disease and Other Dementias (2nd edition). Oxford University Press.

1) Eppig, J., Werhane, M., Edmonds, E. C., Delano-Wood, L., Bangen, K. J., Jak, A. J., Thomas, K. R., Wong, C. G., Weigand, A. J., & Bondi, M. W. (2020). Neuropsychological Diagnostic Criteria for Mild Cognitive Impairment Associated with Alzheimer’s Disease. In D.J. Libon, M. Lamar, K.M. Heilman, & R. Swenson (Eds.), Vascular Disease, Alzheimer’s Disease, and Mild Cognitive Impairment: Advancing an Integrated Approach. (pp. 52-82). Oxford University Press.

Media coverage

Press releases from Neurology and UCSD for our paper on anticholinergic medications, risk for incident mild cognitive impairment, and rate of cognitive decline. Also covered by US News & World Report, Psychology Today, Science Daily, Mental Daily, The Pharmaceutical Journal, Pharmacy Times, Practical Neurology, Sharp Brains, dailyhunt, News Medical Life Sciences, Being Patient, Technology Networks, Medical Dialogues, The Tribune, International Business Times, Newsy Today, News Degree, Today News, OnMedica, Bel Marra Health, Health News Digest, newswise, Study Finds, Pharmacy Practice News, Practice Update, Physician's Briefing, Gilmore Health News, Optimal Health and Wellness, Consumer Affairs, healthing.ca, Your Life Choices, Health Day, News Himalaya, Daily Hunt, Pittwater Online News, News Karnataka, British Asia, drugs.com, Sakal Times, Fars. News Agency, NewsGram, NP News 24, and more.

Selected as ISTAART Member in the News in September 2020 for the media coverage of our paper on anticholinergic medications, risk for incident mild cognitive impairment, and rate of cognitive decline.

AlzForum coverage of our paper that examined effects of APOE  genotype on tau PET associations with memory.