Publications
137. Vinayak Juvekar, Yu Cao, Chang Woo Koh, Dong Joon Lee, Sun Young Kwak, Sun Mi Kim, Tae Jun Park, Sungnam Park,* Zhihong Liu,* and Hwan Myung Kim* "Overcoming melanin interference in melanocyte photodynamic therapy with a pyrene-derived two-photon photosensitizer" Chem. Eng. J. 2024, 493, 152796.
136. Van-Nghia Nguyen, Dong Joon Lee, Dianqi Zhang, Jeongsun Ha, Kunemadihalli Mathada Kotraiah Swamy, Rui Wang,* Hwan Myung Kim,* Fabiao Yu,* and Juyoung Yoon* "Rational Design of Efficient Heavy-Atom-Free Boron-Dipyrromethene Nanophotosensitizers for Two-Photon Excited Photodynamic Therapy of Cancer" Chem. Mater. 2024, 36, 5534-5541.
135. Kim, E. S.; Lee, J.-M.; Kwak, J.-Y.; Lee, H. W.; Lee, I.-J.*; Kim, H. M.* "Multi-Color Two-Photon Microscopy Imaging of Lipid Droplets and Liver Capsule Macrophages in Vivo" Anal. Chem. 2024, 96, 8467-8473.
134. Juvekar, V.; Lee, D. J.; Park, T. G.; Samanta, R.; Kasar, P.; Kim, C.; Rotermund, F.*; Kim, H. M.* "Two-photon excitation photosensitizers for photodynamic therapy: From small-molecules to nano-complex systems" Coord. Chem. Rev. 2024, 506, 215711. (Invited in special issue "Phototherapy")
133. Morozov, B. S.; Gargiulo, F.; Ghule, S; Lee, D. J.; Hampel, F.; Kim, H. M.*; Kataev, E. A.* "Macrocyclic Conformational Switch Coupled with Pyridinium-Induced PET for Fluorescence Detection of Adenosine Triphosphate" J. Am. Chem. Soc. 2024, 146, 7105.
132. Juvekar, V.; Kim, H. M.* "Chapter 6: Two-Photon Fluorescent Probes"; Editors: Wu, L.; Sedgwick, A. C.; He, X.-P.; James, T. D., Fluorescent Chemosensors (Royal Society of Chemistry) 2023, 106-123. (DOI: https://doi.org/10.1039/9781839167324)
131. Lee, H. W.; Juvekar, V.; Lee, D. J.; Kim, H. M.* "Recent advances in organelle-specific two-photon small-molecule fluorescent probes for bioanalysis in live tissues" TrAC-Trends Anal. Chem. 2023, 165, 117128. (Invited in special issue "Luminescence Probes")
130. Pham, T. C.; Lee, D. J.; Kim, D. H.; Yoon, J.; Lam, T. D.; Kim, H. M.*; Lee, S* "Imidazole–carbazole conjugate for two-photon-excited photodynamic therapy and fluorescence bioimaging" Chem. Commun. 2023, 59, 4503-4506.
129. Lee, D. J.†; Kim, E. S.†; Lee, H. W.*; Kim, H. M.* "Advances in Small Molecule Two-Photon Fluorescent Trackers for Lipid Droplets in Live Sample Imaging" Front. Chem. 2022, 10, 1072143. (Invited in Themed Issue "Fluorescent Probe Technologies for Imaging Biospecies")
128. Lee, H. W.†; Tanmay, K. P.†; Lee, I.-J.†; Lee, J.-M.; Kim, B. R.; Kwak, S. Y.; Kim, H. M.* "In Vivo Simultaneous Imaging of Plasma Membrane and Lipid Droplets in Hepatic Steatosis using Red-Emissive Two-Photon Probes" Anal. Chem. 2022, 94, 15100-15107.
127. Juvekar, V.†; Lee, H. W.†; Lee, D. J.†; Kim, H. M.* "Two-Photon Fluorescent Probes for Quantitative Bio-Imaging Analysis in Live Tissues" TrAC-Trends Anal. Chem. 2022, 157, 116787.
126. Lee, C.-G.†; Lee, S.-J.; Park, S.†; Choi, S.-E; Song, M.-W.; Lee, H. W.; Kim, H. J.; Kang, Y.; Lee, K. W.; Kim, H. M.; Kwak, J.-Y.*; Lee, I.-J.; Jeon, J. Y.* "In Vivo Two-photon Imaging Analysis of Dynamic Degradation of Hepatic Lipid Droplets in MS-275-Treated Mouse Liver" Int. J. Mol. Sci. 2022, 23, 9978.
125. Lee, H. W.; Lee, I.-J.; Lee, S.-J.; Kim, Y. R.; Kim, H. M.* "Highly Sensitive Two-Photon Lipid Droplet Tracker for In Vivo Screening of Drug Induced Liver Injury" ACS Sens. 2022, 7, 1027-1035.
124. Kwon, N.†; Lim, C. S.†; Lee, D.; Ko, G.; Ha, J.; Cho, M.; Swamy, K. M. K.; Lee, E.-Y.; Lee, D. J.; Nam, S.-J.; Zhou, X.*; Kim, H. M.*; Yoon, J.* "A coumarin-based reversible two-photon fluorescence probe for imaging glutathione near N-methyl-D-aspartate (NMDA) receptors" Chem. Commun. 2022, 58, 3633-3636 (Themed Issue in Multimolecular Crowding in Biosystems).
123. Han, J.†; Lee, H. W.†; Chen, Y.; Li, H.*, Kim, H. M.*; Yoon, J.* "Observing Hepatic Steatosis with a Commercially Viable Two-Photon Fluorogenic Probe" Mater. Chem. Front. 2022, 6, 553-560 (HOT article).
122. Lee, D. J.†; Juvekar, V.†; Lee, H. W.; Kim, E. S.; Noh, C.-K.; Shin, S. J.*; Kim, H. M.* "Cancer targeted azo dye for two-photon photodynamic therapy in human colon tissue" Anal. Chem. 2021, 93, 16821-16827.
121. Lee, H. W.†; Juvekar, V.†; Lee, D. J.; Kim, S. M.; Kim, H. M.* "Highly Stable Red-Emissive Ratiometric Probe for β-galactosidase Activity using Fluorescence Microscopy and Flow Cytometry" Anal. Chem. 2021, 93, 14778-14783.
120. Wu, L.†; Tian, X.†; Lee, D. J.; Yoon, J.; Lim, C. S.*; Kim, H. M.*; James, T. D.* "Two-photon ESIPT-based fluorescent probe using 4-hydroxyisoindoline-1,3-dione for the detection of peroxynitrite" Chem. Commun. 2021, 57, 11084-11087.
119. Lopez-Alled, C. M.; Park, S. J.; Lee, D. J.; Murfin, L. C.; Kociok-Kohn, G.; Hann, J. L.; Wenk, J.*; James, T. D.*; Kim, H. M.*; Lewis, S. E.* "Azulene-based fluorescent chemosensor for adenosine diphosphate" Chem. Commun. 2021, 57, 10608-10611.
118. Cui, Y.†; Park, S. J.†; Wu, X.; Wang, R.; Qi, S.; Kim, H. M.*; Yoon, J.* "Highly selective two-photon fluorescent off–on probes for imaging tyrosinase activity in living cells and tissues" Chem. Commun. 2021, 57, 6911-6914.
117. Kwon, N.†; Lim, C. S.†; Ko, G.†; Ha, J.†; Lee, D.; Yin, J.*; Kim, H. M.*; Yoon, J.* "Fluorescence Probe for Imaging N-Methyl-d-aspartate Receptors and Monitoring GSH Selectively Using Two-Photon Microscopy" Anal. Chem. 2021, 93, 11612-11616.
116. Noh, C. K.†; Lim, C. S.†; Lee, G. H.; Cho, M. K.; Lee, H. W.; Roh, J.; Kim, Y. B.; Lee, E.; Park, B.; Kim, H. M.*; Shin, S. J.* "A Diagnostic Method for Gastric Cancer Using Two-Photon Microscopy with Enzyme-Selective Fluorescent Probes: A Pilot Study" Front. Oncol. 2021, 11, 634219.
115. Juvekar, V.†; Cho, M. K.†; Lee, H. W.†; Lee, D. J.; Kang, H.; Song, J. M.; Je, J. T.*; Kim, H. M.* "A red-emissive two-photon fluorescent probe for mitochondrial sodium ions in live tissue" Chem. Commun. 2021, 57, 8929-8932.
114. Pham, T. C.; Nguyen V. N.; Choi, Y.; Kim, D.; Jung, O. S.; Lee, D. J.; Kim, H. J.; Lee, M. W.; Yoon, J.; Kim, H. M.*; Lee, S* "Hypochlorite-Activated Fluorescence Emission and Antibacterial Activities of Imidazole Derivatives for Biological Applications" Front. Chem. 2021, 9, 713078.
113. Juvekar, V.; Lee, H. W.; Kim, H. M.* "Two-Photon Fluorescent Probes for Detecting Enzyme Activities in Live Tissues" ACS Appl. Bio Mater. 2021, 4, 2957-2973 (invited).
112. Juvekar, V.†; Lim, C. S.†; Lee, D. J.; Song, D. H.; Noh, C. K.; Kang, H.; Shin, S. J.*; Kim, H. M.* "Near-Infrared Ratiometric Two-Photon Probe for pH Measurement in Human Stomach Cancer Tissue" ACS Appl. Bio Mater. 2021, 4, 2135-2141 (Invited in special issue "Biospecies Sensors").
111. Park, S. J.; Cho, M. K.; Lee, D. J.; Song, D. H.; Lim, C. S.; Noh, C. K.; Lee, D. M.; Choi, K. S.*; Shin, S. J.*; Kim, H. M.* "Development of two-photon fluorescence probe for detecting cyclooxygenase-2 level in human colorectal cancer tissue" Sens. Actuator B-Chem. 2021, 330, 129329.
110. Lim, C. S.; Choi, J. W.; Kim, Y. C.*; Kim, H. M.* "Analyzing Nonmelanoma Skin Cancer Using Enzyme-Activatable Two-Photon Probes" Bull. Korean. Chem. Soc. 2021, 42, 103-106 (invited in special issue "Chemosensors and Imaging probes").
109. Juvekar, V.†; Lim, C. S.†; Lee, D. J.; Song, G. O.; Kang, H.; Kim, H. M.* "An azo dye for photodynamic therapy that is activated selectively by two-photon excitation" Chem. Sci. 2021, 12, 427-434.
108. Juvekar, V.†; Park, S, J,†; Yoon, J.*; Kim, H. M.* "Recent progress in the two-photon fluorescent probes for metal ions" Coord. Chem. Rev. 2021, 427, 213574 (invited in special issue "Metal as a guest or host").
107. Nguyen, V.†; Park, S. J.†; Qi, S.; Ha, J.; Heo, S.; Yim, Y.; Baek, G.; Lim C. S.; Lee, D. J.; Kim H. M.*; Yoon, J. "Design and synthesis of efficient heavy-atom-free photosensitizers for photodynamic therapy of cancer" Chem. Commun. 2020, 56, 11489-11492.
106. Cho, M. K.†; Seo, M. J.†; Juvekar, V.; Jo, J. H.; Kim, W.; Choi, K. S.*; Kim, H. M.* "Screening of Drug-Induced Steatosis and Phospholipidosis Using Lipid Droplet-Selective Two-Photon Probes" Anal. Chem. 2020, 92, 11223-11231.
105. Chung, J.†; Li, H.†; Lim, C. S.†; Kim, H. M.*; Yoon, J.* Two-photon imaging of hydrogen polysulfides in living cells and hippocampal tissues" Sens. Actuator B-Chem, 2020, 332, 128564.
104. Odyniec, M. L.; Park, S. J.; Gardiner, J. E.; Webb, E. C.; Sedgwick, A. C.; Yoon, J.; Bull, S. D.*; Kim, H. M.*; James, T. D.* "A Fluorescent ESIPT-based Benzimidazole Platform for the Ratiometric Two-Photon Imaging of ONOO- In Vitro and Ex Vivo" Chem. Sci. 2020, 11, 7329-7334.
103. Kumar, H.; Lim, C. S.; Choi, H.; Joshi, H. P.; Kim, K.-T.; Kim, Y. H.; Park, C.-K.; Kim, H. M.; Han, I.-B.* "Elevated TRPV4 Levels Contribute to Endothelial Damage and Scarring in Experimental Spinal Cord Injury" J. Neurosci. 2020, 40, 1943-1955.
102. Kim, D.; Lee, J. H.; Koo, J. Y.; Kim, H. M.; Park, S. B.* "Two-Photon and Multicolor Fluorogenic Bioorthogonal Probes Based on Tetrazine-Conjugated Naphthalene Fluorophores" Bioconjugate Chem. 2020, 31, 1545-1550.
101. Park, S. J.†; Juvekar, V.†; Jo, J. H.; Kim, H. M.* "Combining hydrophilic and hydrophobic environment sensitive dyes to detect wide range of cellular polarity" Chem. Sci. 2020, 11, 596-601.
100. Park, S. J.; Shin, B. K.; Lee, H. W.; Song, J. M.; Je, J. T.*; Kim, H. M.* "Asymmetric cyanine as a far-red fluorescence probe for mitochondrial viscosity" Dyes. Pigment. 2020, 174, 108080.
99. Murfin, L. C.†; Weber, M.†; Park, S. J.†; Kim, W. T.†; Lopez-Alled, C. M.; McMullin, C. L.; Pradaux-Caggiano, F.; Lyall, C. L.; Kociok-Köhn, G.; Wenk, J.; Bull, S. D.; Yoon, J.; Kim, H. M.*; James, T. D.*; Lewis, S. E.* "Azulene-Derived Fluorescent Probe for Bioimaging: Detection of Reactive Oxygen and Nitrogen Species by Two-Photon Microscopy" J. Am. Chem. Soc. 2019, 141, 19389-19396.
98. Lee, H. W.; Lim, C. S.; Choi, H.; Cho, M. K.; Noh, C.-K.; Lee, K.*; Shin, S. J.*; Kim, H. M.* "Discrimination between Human Colorectal Neoplasms with a Dual-Recognitive Two-Photon Probe" Anal. Chem. 2019, 91, 14705-14711.
97. Chen, L.†; Cho, M. K.†; Wu, D.; Kim, H. M.*; Yoon, J.* "A two-photon fluorescence probe for selective monitoring of superoxide in live cells and tissues" Anal. Chem. 2019, 91, 14691-14696.
96. Kim, Y. J.†; Park, S. J.†; Lim, C. S.; Lee, D. J.; Noh, C.; Lee, K.; Shin, S. J.*; Kim, H. M.* "Ratiometric Detection of γ-Glutamyltransferase in Human Colon Cancer Tissues using a Two-photon Probe" Anal. Chem. 2019, 91, 9246-9250.
95. Yoon, Y.; Jo, S.; Park, S. J.; Kim, H. M.; Kim, D.; Lee, T. S.* "Unusual fluorescence of o-phenylazonaphthol derivatives with aggregation-induced emission and their use in two-photon cell imaging" Chem. Commun. 2019, 55, 6747-6750.
94. Cho, M. K.†; Juvekar, V.†; Lim, C. S.; Noh, C.; Shin, S. J.*; Kim, H. M.* "A Highly Sensitive Two-Photon Ratiometric Probe for Rapid Detection of the hNQO1 Enzyme in Colon Cancer Tissue" Asian J. Org. Chem. 2019. 8, 1707-1712 (Invited in themed issue "Researchers in Korea").
93. Chen, L.†; Park, S. J.†; Wu, D.*; Kim, H. M.*; Yoon, J.* "A two-photon fluorescence probe for colorimetric and ratiometric monitoring of mercury in live cells and tissues" Chem. Commun. 2019. 55, 1766-1769.
92. Choi, H. J.; Lim, C. S.; Cho, M. K.; Kang, J. S.; Park, S. J.; Park, S. M.*; Kim, H. M.* "A Two-Photon Ratiometric Probe for Hydrogen Polysulfide (H2Sn): Increase in Mitochondrial H2Sn Production in a Parkinson's Disease Model" Sens. Actuator B-Chem. 2019, 283, 810-819.
91. Chang, M. J.; Kim, K.; Park, K. S.; Kang, J. S.; Lim, C. S.*; Kim, H. M.*; Kang, C,*; Lee, M. H.* "High-depth fluorescence imaging using a two-photon FRET system for mitochondrial pH in live cells and tissues" Chem. Commun. 2018, 54, 13531-13534.
90. Pak, Y.†; Park, S. J.†; Song, G.; Yim, Y.; Kang, H.; Kim, H. M.*; Bouffard, J.*; Yoon, J.* "Endoplasmic Reticulum-Targeted Ratiometric N-Heterocyclic Carbene Borane Probe for Two-Photon Microscopic Imaging of Hypochlorous Acid" Anal. Chem. 2018. 90, 12937-12943.
89. Jo, A.†; Sung, J.†; Lee, S.; Nam, H.; Lee, H. W.; Park, J.; Kim, H. M.; Kim, E.*; Park, S. B.* "Near-IR Fluorescent Tracer for Glucose-Uptake Monitoring in Live Cells" Bioconjugate Chem. 2018, 29, 3394-3401.
88. Park, S. J.; Kim, Y. J.; Kang, J. S.; Kim, I. Y.; Choi, K. S.; Kim, H. M.* "Carboxylesterase-2-Selective Two-Photon Ratiometric Probe Reveals Decreased Carboxylesterase-2 Activity in Breast Cancer Cells" Anal. Chem. 2018, 90, 9465-9471.
87. Pak, Y. L.†; Park, S. J.†; Xu, Q.; Kim, H. M.*; Yoon, J.* "A Ratiometric Two-photon Fluorescent Probe for Detecting and Imaging Hypochlorite" Anal. Chem. 2018, 90, 9510-9514.
86. Lee, D.†; Lim, C. S.†; Ko, G.†; Kim, D.; Cho, M. K.; Nam, S. J.; Kim, H. M.*; Yoon, J.* "A Two-Photon Fluorescent Probe for Imaging Endogenous ONOO- near NMDA Receptors in Neuronal Cells and Hippocampal Tissues" Anal. Chem. 2018, 90, 9347-9352.
85. Si, H. Y.†; Cho, M. K.†; Kang, J. S.; Noh, C.; Shin, S. J.; Lim, C. S.*; Kim, H. M.* "Carboxylate-containing two-photon probe for simultaneous detection of extra- and intracellular pH values in colon cancer tissue" Anal. Chem. 2018, 90, 8058-8064.
84. Cho, M. K.†; Lim, C. S.†; Sarkar, A. R.; Lee, H. W.; Choi, H. J.; Noh, C.; Shin, S. J.*; Kim, H. M.* "A Two-Photon Ratiometric Probe for Detection of hNQO1 Enzyme Activity in Human Colon Tissue" Sens. Actuator B-Chem. 2018, 272, 203-210.
83. Chen, L.†; Park, S. J.†; Wu, D.; Kim, H. M.*; Yoon, J.* "A two-photon ESIPT based fluorescence probe for specific detection of hypochlorite" Dyes. Pigment. 2018, 158, 526-532.
82. Park, S. S.; Lee, D. M.; Lim, J. H.; Lee, D.; Park, S. J.; Kim, H. M.; Sohn, S.; Yoon, G.; Eom, Y. W.; Jeong, S. Y.; Choi, E. K.*; Choi, K. S.* "Pyrrolidine dithiocarbamate reverses Bcl-xL-mediated apoptotic resistance to doxorubicin by inducing paraptosis" Carcinogenesis 2018, 39, 458-470.
81. Pak, Y. L.†; Park, S. J.†; Wu, D.†; Cheon, B.; Kim, H. M.*; Bouffard, J.*; Yoon, J.* "N-Heterocyclic Carbene Boranes as Reactive Oxygen Species-Responsive Materials: Application to the Two-Photon Imaging of Hypochlorous Acid in Living Cells and Tissues" Angew. Chem. Int. Ed. 2018, 57, 1567-1571.
80. Li, J.†; Kwon, Y.†; Chung, K. S.†; Lim, C. S.†; Lee, D.; Yue, Y.; Yoon, J.; Kim, G.; Nam, S. J.; Chung, T. W.; Kim, H. M*; Yin, C.*; Ryu, J. H.*; Yoon, J* "Naphthalene-based fluorescent probes for glutathione and their applications in living cells and patients with sepsis" Theranostics 2018, 8, 1411-1420.
79. Lim, C. S.†; Cho, M. K.†; Park, M. Y.; Kim, H. M.* "A Two-Photon Ratiometric Fluorescent Probe for Imaging of Hydrogen Peroxide Levels in Rat Organ Tissues" ChemistryOpen 2018, 7, 53-56 (Invited in themed issue "Chemosensors: Recent Developments").
78. Majumdar, A.; Lim, C. S.; Kim, H. M.;* Ghosh, K.* "New Six-Membered pH-Insensitive Rhodamine Spirocycle in Selective Sensing of Cu2+ through C-C Bond Cleavage and Its Application in Cell Imaging" ACS Omega 2017, 2, 8167-8176.
77. Li, J.†; Lim, C. S.†; Kim, G.; Kim, H. M.*; Yoon, J.* "Highly Selective and Sensitive Two-Photon Fluorescence Probe for Endogenous Peroxynitrite Detection and Its Applications in Living cells and Tissues" Anal. Chem. 2017, 89, 8496-8500.
76. Kim, H. J.†; Lim, C. S.†; Lee, H. W.; Lee, H. S.; Um, Y. J.; Kumar, H.; Han, I.; Kim, H. M.* "A ratiometric two-photon probe for Ca2+ in live tissues and its application to spinal cord injury model" Biomaterials. 2017, 141, 251-259.
75. Moon, J. Y.; Choi, S. J.; Heo, C. H.; Kim, H. M.; Kim, H. S.* "α-Syntrophin stabilizes catalase to reduce endogenous reactive oxygen species levels during myoblast differentiation" FEBS J. 2017, 284, 2052-2065.
74. Lee, H. W.; Cho, M. K.; Kim, H.; Lim, C. S.; Kang, C.*; Kim, H. M.* "Visualization of Vesicular Transport from the Endoplasmic Reticulum to Lysosome using an Amidine Derived Two‐Photon Probe" Chem. Commun. 2017, 53, 6097-6100 (Invited in themed issue "Chemosensors and Molecular logic").
73. Chen, L. Y.; Wu, D.*; Lim, C. S.; Kim, D.; Nam, S. J.; Lee, W.; Kim, G.; Kim, H. M.*; Yoon, J.* "A Two-Photon Fluorescent Probe for Specific Detection of Hydrogen Sulfide Based on a Familiar ESIPT Fluorophore bearing AIE Characteristics" Chem. Commun. 2017, 53, 4791-4794.
72. Chen, X.†; Lim, C. S.†; Lee, D.†; Lee, S.; Park, S. J.; Kim, H. M.*; Yoon, J.* "Two-photon fluorescence sensors for imaging NMDA receptors and monitoring release of Zn2+ from the presynaptic terminal" Biosens. Bioelectron. 2017, 91, 770-779.
71. Agrawalla, B. K.; Lee, H. W.; Phue, W. H.; Raju, A.; Kim, J. J.; Kim, H. M.; Kang, N. Y.*; Chang, Y. T.* "Two-Photon Dye Cocktail for Dual-Color 3D Imaging of Pancreatic Beta and Alpha Cells in Live Islets" J. Am. Chem. Soc. 2017, 139, 3480-3487.
70. Kwon, N.†; Cho, M. K.†; Park, S. J.; Kim, D.; Nam, S. J.; Cui, L.; Kim, H. M.*; Yoon, J.* "Efficient Two-Photon Fluorescent Probe for Human NAD(P)H:Quinone Oxidoreductase (hNQO1) Detection and Imaging in Tumor Cells" Chem. Commun. 2017, 53, 525-528.
69. Joe, A.; Park, S. H.; Shim, K. D.; Kim, D. J.; Jhee, K. H.; Lee, H. W.; Heo, C. H.; Kim, H. M.; Jang, E. S.* "Antibacterial mechanism of ZnO nanoparticles under dark conditions" J. Ind. Eng. Chem. 2017, 45, 430-439.
68. Heo, C. H.; Cho, M. K.; Shin, S.; Yoo, T. H.*; Kim, H. M.* "Real-Time Monitoring of Vesicle pH in an Endocytic Pathway using an EGF-Conjugated Two-Photon Probe" Chem. Commun. 2016, 52, 14007-14010 (Invited in themed issue "Biological optical imaging").
67. Koo, J. Y.; Heo, C. H.; Shin, Y.-H.; Kim, D.; Lim, C. S.; Cho, B. R.; Kim, H. M.; Park, S. B.* "Readily Accessible and Predictable Naphthalene-Based Two-Photon Fluorophore with Full Visible-Color Coverage" Chem. Eur. J. 2016, 22, 14166-14170.
66. Baek, Y.; Park, S. J.; Zhou, X.*; Kim, G.; Kim, H. M.*; Yoon, J.* "A viscosity sensitive fluorescent dye for real-time monitoring of mitochondria transport in neurons" Biosens. Bioelectron. 2016, 86, 885-891.
65. Xu, Q.†; Heo, C. H.†; Kim, J. A.†; Lee, H. S.; Hu, Y.; Kim, D.; Swamy, K. M. K.; Kim, G.; Nam, S.; Kim, H. M.*; Yoon, J.* "A Selective Imidazoline-2-thione-Bearing Two-Photon Fluorescent Probe for Hypochlorous Acid in Mitochondria" Anal. Chem. 2016, 88, 6615-6620.
64. Heo, C. H.†; Sarkar, A. R.†; Baik, S. H.†; Jung, T. S.; Kim, J. J.; Kang, H.; Mook-J., I.*; Kim, H. M.* "A Quadrupolar Two-Photon Fluorescent Probe for In Vivo Imaging of Amyloid-β Plaques" Chem. Sci. 2016, 7, 4600-4606.
63. Park, S. J.; Lee, H. W.; Kim, H.; Kang, C.*; Kim, H. M.* "A Carboxylesterase-Selective Ratiometric Fluorescent Two-Photon Probe and Its Application to Hepatocytes and Liver Tissues" Chem. Sci. 2016, 7, 3703-3709.
62. Sarkar, A.R.†; Heo, C. H.†; Xu, L.; Lee, H. W.; Si, H. Y.; Byun, J. W.; Kim, H. M.* "A Ratiometric Two-Photon Probe for Quantitative Imaging of Mitochondrial pH Values" Chem. Sci. 2016, 7, 766-773.
61. Park, J.; Heo, C. H.; Kim, H. M.*; Hong, J. I.*, "Two-photon fluorescent probe for peroxynitrite" Tetrahedron Lett. 2016, 57, 715-718.
60. Choi, J.-A.; Jung, Y. S.; Kim, J. Y.; Kim, H. M.; Lim, I. K.* "Inhibition of breast cancer invasion by TIS21/BTG2/Pc3-Akt1-Sp1-Nox4 pathway targeting actin nucleators, mDia genes" Oncogene 2016, 35, 83-93.
59. Cha, S. H.; Choi, Y. R.; Heo, C. H.; Kang, S. J.; Joe, E. H.; Jou. I.; Kim, H. M.; Park, S. M.* "Loss of parkin promotes lipid rafts-dependent endocytosis through accumulating caveolin-1: implications for Parkinson's disease" Mol. Neurodegeneration 2015, 10, 63.
58. Pramanik, S.; Bhalla, V.; Kim, H. M.; Singh, H.; Lee, H. W.; Kumar, M.* "Hexaphenylbenzene Based AIEE Active Two Photon Probe for Detection of Hydrogen Sulfide with Tunable Self-assembly in Aqueous Media and Application in Live cell Imaging" Chem. Commun. 2015, 51, 15570-15573.
57. Choi, Y-M.; Kim, H-K.; Shim, W.; Anwar, M. A.; Kwon, J-W.; Kwon, H-K.; Kim, H. J.; Jeong, H.; Kim, H. M.; Hwang, D.; Kim, H. S.; Choi, S.* "Mechanism of Cisplatin-Induced Cytotoxicity Is Correlated to Impaired Metabolism Due to Mitochondrial ROS Generation" PLoS ONE, 2015, 10, e0135083.
56. Singh, H.†; Lee, H. W.†; Heo, C. H.; Byun, J. W.; Sarkar, A. R.; Kim, H. M.* "A Golgi-localized two-photon probe for imaging zinc ions" Chem. Commun. 2015, 51, 12099-12102.
55. Kim, H. M.*; Cho, B. R.* "Small-Molecule Two-Photon Probes for Bioimaging Applications" Chem. Rev. 2015, 115, 5014-5055.
54. Hu, Y.; Heo, C. H.; Kim, G.; Jun, E. J.; Yin, J.; Kim, H. M.*; Yoon, J.* "One-Photon and Two-Photon Sensing of Biothiols Using a Bis-Pyrene-Cu(II) Ensemble and Its Application To Image GSH in the Cells and Tissues" Anal. Chem. 2015, 87, 3308-3313.
53. Xu, Q.†; Heo, C. H.†; Kim, G.; Lee, H. W.; Kim, H. M.*; Yoon, J.* "Development of Imidazoline-2-Thiones Based Two-Photon Fluorescence Probes for Imaging Hypochlorite Generation in a Co-Culture System" Angew. Chem. Int. Ed. 2015, 54, 4890-4894.
52. Sarkar, A. R.†; Heo, C. H.†; Kim, E.; Lee, H. W.; Singh, H.; Kim, J. J.; Kang, H.; Kang, C.*; Kim, H. M.* "A cysteamine-selective two-photon fluorescent probe for ratiometric bioimaging" Chem. Commun. 2015, 51, 2407-2410.
51. Lee, H. W.†; Heo, C. H.†; Sen, D.; Byun, H.-O.; Kwak, I. H.; Yoon, G.*; Kim, H. M.* "Ratiometric Two-Photon Fluorescent Probe for Quantitative Detection of β Galactosidase Activity in Senescent Cells" Anal. Chem. 2014, 86, 10001-10005.
50. Sarkar, A. R.†; Heo, C. H.†; Lee, H. W.; Park, K. H.; Suh, Y. H.; Kim, H. M.* "Red Emissive Two-Photon Probe for Real-Time Imaging of Mitochondria Trafficking" Anal. Chem. 2014, 86, 5638-5641.
49. Dong, X.†; Heo, C. H.†; Chen, S.; Kim, H. M.*; Liu, Z.* "Quinoline-Based Two-Photon Fluorescent Probe for Nitric Oxide in Live Cells and Tissues" Anal. Chem. 2014, 86, 308-311.
48. Sarkar, A. R.; Kang, D. E.; Kim, H. M.*; Cho, B. R.* "Two-photon Fluorescent Probes for Metal Ions in Live Tissues" Inorg. Chem. 2014, 53, 1794-1803 (Cover).
47. Sarkar, A. R.; Heo, C. H.; Park, M. Y.; Lee, H. W.; Kim, H. M.* "A small molecule two-photon fluorescent probe for intracellular sodium ions" Chem. Commun. 2014, 50, 1309-1312.
46. Kim, H. J.†; Heo, C. H.†; Kim, H. M.* “Benzimidazole-Based Ratiometric Two-Photon Fluorescent Probes for Acidic pH in Live Cells and Tissues" J. Am. Chem. Soc. 2013, 135, 17969-17977.
45. Jung, H. J.; Sohn, W. Y.; Heo, C. H.; Kim, H. M.; Ishiuchi, S.; Fujii, M.; Kang, H.* “Gas-Phase Spectroscopy of Laser-Desorbed Acedan and Proline-Acedan” Bull. Korean Chem. Soc. 2013, 34, 2241-2242.
44. Bae, S. K.†; Heo, C. H.†; Choi, D. J.†; Sen, D.; Cho, E. H.*; Cho, B. R.*; Kim, H. M.* “A Ratiometric Two-Photon Fluorescent Probe Reveals Reduction in Mitochondrial H2S Production in a Parkinson’s Disease Gene Knockout Astrocytes" J. Am. Chem. Soc. 2013, 135, 9915–9923.
43. Kim, H. M.*; Cho, B. R.* “Mitochondrial-Targeted Two-Photon Fluorescent Probes for Zinc Ions, H2O2, and Thiols in Living Tissues” Oxid. Med. Cell. Longev. 2013, 323619.
42. Heo, C. H.†; Kim, K. H.†; Kim, H. J.; Baik, S. H.; Song, H. D; Kim, Y. S.; Lee, J. W.; Mook-J., I.*; Kim, H. M.* “A two-photon fluorescent probe for amyloid-ß plaques in living mice" Chem. Commun. 2013, 49, 1303–1305.
41. Han, J. H.; Park, S. K.; Lim, C. S.; Park, M. K.; Kim, H. J.; Kim, H. M.*; Cho, B. R.* “Simultaneous Imaging of Mitochondria and Lysosomes by Using Two-Photon Fluorescent Probes" Chem. Eur. J. 2012, 18, 15246–15249.
40. Dong, X.; Han, J. H.; Heo, C. H.; Kim, H. M.*; Liu, Z.*; Cho, B. R.* “Dual-Color Imaging of Magnesium/Calcium Ion Activities with Two-Photon Fluorescent Probes" Anal. Chem. 2012, 84, 8110–8113.
39. Seo, E. W.†; Han, J. H.†; Heo, C. H.; Shin, J. H.; Kim, H. M.*; Cho, B. R.* “A Small-Molecule Two-Photon Probe for Nitric Oxide in Living Tissue" Chem. Eur. J. 2012, 18, 12388-12394.
38. Baek, N. Y.†; Heo, C. H.†; Lim, C. S.; Masanta, G.; Cho, B. R.*; Kim, H. M.* “A Highly Sensitive Two-Photon Fluorescent Probe for Mitochondrial Zinc Ions in Living Tissue" Chem. Commun. 2012, 48, 4546-4548 (Inside Cover).
37. Masanta, G.†; Heo, C. H.†; Lim, C. S.; Bae, S. K.; Cho, B. R.*; Kim, H. M.* “A Mitochondria-Localized Two-Photon Fluorescent Probe for Ratiometric Imaging of Hydrogen Peroxide in Live Tissue" Chem. Commun. 2012, 48, 3518-3520.
36. Kang, M. Y.†; Lim, C. S.†; Kim, H. S.; Seo, E. W.; Kim, H. M.*; Kwon, O. H.*; Cho, B. R.* “Detection of Nickel in Fish Organs with a Two-Photon Fluorescent Probe" Chem. Eur. J. 2012, 18, 1953-1960.
35. Lim, C. S.†; Chung, C.†; Kim, H. M.; An, M. J.; Tian, Y. S.; Chun, H. J.; Cho, B. R.* “A two-photon turn-on probe for glucose uptake" Chem. Commun. 2012, 48, 2122-2124.
34. Lim, C. S.; Masanta, G.; Kim, H. J.; Han, J. H.; Kim, H. M.*; Cho, B. R.* “Ratiometric Detection of Mitochondrial-Thiols with a Two-Photon Fluorescent Probe” J. Am. Chem. Soc. 2011, 133, 11132-11135.
33. Masanta, G.; Lim, C. S.; Kim, H. J.; Han, J. H.; Kim, H. M.*; Cho, B. R.* “A Mitochondrial-Targeted Two-Photon Probe for Zinc Ion” J. Am. Chem. Soc. 2011, 133, 5698-5700.
32. Lim, C. S.; Kim, H. J.; Lee, J. H.; Tian, Y. S.; Kim, C. H.; Kim, H. M.*; Joo, T.*; Cho, B. R.* “A Two-Photon Turn-On Probe for Lipid Rafts with Minimum Internalization” ChemBioChem 2011, 12, 392-395 (Cover).
31. Kim, H. M.*; Cho, B. R.* "Two-Photon Fluorescent Probes for Metal Ions" Chem.-Asian J. 2011, 6, 58-69.
30. Kim, H. J.†; Han, J. H.†; Kim, M. K.; Lim, C. S.; Kim, H. M.*; Cho, B. R.* “Dual-Color Imaging of Sodium/Calcium Ion Activities with Two-Photon Fluorescent Probes” Angew. Chem. Int. Ed. 2010, 49, 6786-6789 (Hot Article).
29. Kim, M. K.†; Lim, C. S.†; Hong, J. T.; Han, J. H.; Jang, H.Y.; Kim, H. M.*; Cho, B. R.* “Sodium Ion Selective Two-Photon Fluorescent Probe for In Vivo Imaging” Angew. Chem. Int. Ed. 2010, 49, 364-367.
28. Kim, H. M.; Seo, M. S.; Jeon, S.-J.; Cho, B. R. “Two-photon absorption properties of hexa-substituted benzene derivatives. Comparison between dipolar and octupolar molecules” Chem. Commun. 2009, 47, 7422-7424.
27. Tian, Y. S.; Lee, H. Y.; Lim, C. S.; Park, J.; Kim, H. M.; Shin, Y. N.; Kim, E. S.; Jeon, H. J.; Park, S. B.; Cho, B. R. “A Two-Photon Tracer for Glucose Uptake” Angew. Chem. Int. Ed. 2009, 48, 8027-8031.
26. Kim, H. M.; Cho, B. R. “Second-order nonlinear optical properties of octupolar molecules. Structure-property relationship” J. Mater. Chem. 2009, 19, 7402-7409.
25. Yi, J.-S.; Choo, H.-J.; Cho, B. R.; Kim, H. M.; Kim, Y.-N.; Ham, Y.-M.; Ko, Y.-G. “Ginsenoside Rh2 induces ligand-independent Fas activation via lipid raft disruption” Biochem. Biophys. Res. Commun. 2009, 385, 154-159.
24. Kim, H. M.; Cho, B. R. “Two-photon probes for intracellular free metal ions, acidic vesicles, and lipid rafts in live tissues” Acc. Chem. Res. 2009, 42, 863-872.
23. Kim, H. M.; Cho, B. R. “Two-photon materials with large two-photon cross sections. Structure-property relationship” Chem. Commun. 2009, 153-164.
22. Kim, H. M.; Kim, B. R.; Choo, H.-J.; Ko, Y.-G.; Jeon, S.-J.; Kim, C. H.; Joo, T.; Cho, B. R. “Two-photon fluorescent probes for lipid raft imaging: Effect of chain length” ChemBioChem 2008, 9, 2830-2838.
21. Kim, H. M.†; Lee, Y. O.†; Lim, C. S.; Kim, J. S.; Cho, B. R. “Two-photon absorption properties of alkynyl-conjugated pyrene derivatives” J. Org. Chem. 2008, 73, 5127-5130.
20. Kim, H. M.; Seo, M. S.; An, M. J.; Hong, J. H.; Tian, Y. S.; Choi, J. H.; Kwon, O.; Lee, K. J.; Cho, B. R. “Two-Photon Fluorescent Probes for Intracellular Free Zinc Ions in Live Tissue” Angew. Chem. Int. Ed. 2008, 47, 5167-5170.
19. Kim, H. M.; Jeong, B. H.; Hyon, J.-Y.; An, M. J.; Seo, M. S.; Hong, J. H.; Lee, K. J.; Kim, C. H.; Joo, T.; Hong, S.-C.; Cho, B. R. “Two-Photon Fluorescent Turn-On Probe for Lipid Rafts in Live Cell and Tissue” J. Am. Chem. Soc. 2008, 130, 4246-4247.
18. Kim, H. M.; An, M. J.; Hong, J. H.; Jeong, B. H.; Kwon, O.; Hyon, J.-Y.; Hong, S.-C.; Lee, K. J.; Cho, B. R. “Two-Photon Fluorescent Probes for the Acidic Vesicles in Live Cell and Tissue” Angew. Chem. Int. Ed. 2008, 47, 2231-2234.
17. Kim, H. M.; Kim, B. R.; An, M. J.; Hong, J. H.; Lee, K. J.; Cho, B. R. “Two-Photon Fluorescent Probes for Long-Term Imaging of Calcium Waves in Live Tissue” Chem. Eur. J. 2008, 14, 2075-2083.
16. Kim, H. M.; Kim, B. R.; Hong, J. H.; Park, J.-S.; Lee, K. J.; Cho, B. R. “A Two-Photon Fluorescent Probe for Calcium Waves in Live Tissue” Angew. Chem. Int. Ed. 2007, 46, 7445-7448.
15. Pyun, S. Y.; Seok, H. J.; Kim, J. C.; Kim, H. M.; Cho, B. R. “Ketene-Forming Elimination Reactions from Aryl Phenylacetates Promoted by R2NH in MeCN. Effects of Base-Solvent and beta Phenyl Group” J. Phys. Org. Chem. 2007, 20, 685-689.
14. Jeong, M.-Y.; Kim, H. M.; Jeon, S.-J.; Brasselet, S.; Cho, B. R. “Octupolar films with significant 2nd harmonic generation” Adv. Mater. 2007, 19, 2107-2111.
13. Kim, H. M.; Jung, C.; Kim, B. R.; Jung, S.-Y.; Hong, J. H.; Ko, Y.-G.; Lee, K. J.; Cho, B. R. “Environmentally Sensitive Two-Photon Probe for Intracellular Free Mg2+ Ions in Live Tissues” Angew. Chem. Int. Ed. 2007, 46, 3460-3463.
12. Kim, H. M.; Fang, X. Z.; Yang, P. R.; Yi, J.-S.; Ko, Y.-G.; Piao, M. J.; Chung, Y. D.; Park, Y. W.; Jeon, S.-J.; Cho, B. R. “Design of Molecular Two-Photon Probes for In Vivo Imaging. 2H-Benzo[h]chromene-2-one Derivatives” Tetrahedron Lett. 2007, 48, 2791-2795.
11. Kim, H. M.; Yang, P. R.; Seo, M. S.; Yi, J.-S.; Hong, J. H.; Jeon, S.-J.; Ko, Y.-G.; Lee, K. J.; Cho, B. R. “Magnesium Ion-Selective Two-Photon Fluorescent Probe Based on a Benzo[h]chromene Derivative for In vivo Imaging” J. Org. Chem. 2007, 72, 2088-2096.
10. Kim, H. M.; Choo, H.-J.; Jung, S.-Y.; Ko, Y.-G.; Park, W.-H.; Jeon, S.-J.; Kim, C. H.; Joo, T.; Cho, B. R. “A Two-Photon Fluorescent Probe for Lipid Rafts Imaging: C-Laurdan” ChemBioChem 2007, 8, 553-559.
9. Kim, J. S.; Kim, H. J.; Kim, H. M.; Kim, S. H.; Lee, J. W.; Kim, S. K.; Cho, B. R. “Metal Ion Sensing Novel Calix[4]crown Fluoroionophore with Two-Photon Absorption Property” J. Org. Chem. 2006, 71, 8016-8022.
8. Nam, J. R.; Kim, C. H.; Jeoung, S. C.; Lim, K. S.; Kim, H. M.; Jeon, S.-J.; Cho, B. R. “Measurement of two-photon absorption coefficient of dye molecules doped in polymer thin films based on ultrafast laser ablation” Chem. Phys. Lett. 2006, 427, 210-214.
7. Piao, M. J.; Chajara, K.; Yoon, S. J.; Kim, H. M.; Jeon, S.-J.; Kim, T.-H.; Song, K.; Asselberghs, I.; Persoons, A.; Clays, K.; Cho, B. R. “First hyperpolarizabilities of hexa(ethynyl)benzene derivatives: effect of conjugation length” J. Mater. Chem. 2006, 16, 2273-2281.
6. Lee, S. H.; Park, J. R.; Jeong, M.-Y.; Kim, H. M.; Li, S.; Song, J.; Ham, S.; Jeon, S.-J.; Cho, B. R. “First Hyperpolarizabilities of 1,3,5-Tricyanobenzene Derivatives: Origin of Larger β Value for the Octupoles than for the Dipoles” ChemPhysChem. 2006, 7, 206-212.
5. Kim, H. M.; Yang, W. J.; Kim, C. H.; Park, W.-H.; Jeon, S.-J.; Cho, B. R. “Two-Photon Dyes Containing Heterocyclic Rings with Enhanced Photostability” Chem. Eur. J. 2005, 11, 6386-6391.
4. Ahn, H. C.; Yang, S. K.; Kim, H. M.; Li, S.; Jeon, S.-J.; Cho, B. R. “Molecular two-photon sensor for metal ions derived from bis(2-pyridylamine)” Chem. Phys. Lett. 2005, 410, 312-315.
3. Yang, W. J.; Kim, D. Y.; Jeong, M.-Y.; Kim, H. M.; Lee, Y. K.; Fang, X.; Jeon, S.-J.; Cho, B. R. “Two-photon absorption properties of 2,6-bis(styryl)anthracene derivatives. Effects of donor-acceptor substituents and pi-center” Chem. Eur. J. 2005, 11, 4191-4198.
2. Kim, H. M.; Jeong, M.-Y.; Ahn, H. C.; Jeon, S.-J.; Cho, B. R. “Two-photon sensor for metal ions derived from azacrown ether” J. Org. Chem. 2004, 69, 5749-5751.
1. Yang, W. J.; Kim, D. Y.; Jeong, M.-Y.; Kim, H. M.; Jeon, S.-J.; Cho, B. R. “2,6-Bis(styryl)anthracene derivatives with large two-photon cross-sections” Chem. Commun. 2003, 2618-2619.