Bioinformatics projects

Nutrition-informatics session (NCR)

Nutrition informatics recently rises as field of research to analyze, generate and use a nutrition data for person or such group to make a best possible decision for nutrition and medicines , in this talk we will review the nutrition informatics aspects, research, tools and applications and how it’s affecting the climate change and personal health

membrane docking

Genomics annotation

RNAi Docking

in-silico Organism

Nano Docking

I2D: An Interactive Shiny Application for Molecular Interaction Analysis and Visualization

phylogenetic tree

In-silico Nematode Aptamer

we designed an organic molecule “ Aptamer” its RNA target to attach “profilin” protein which nematode secrete to plant cell wall lysis for the infection .

ASU Innovate 1st place award 2022

wiley book chapter

DNA Origami designs

Origami letter project
Origami Sheet

Universal COVID-19 drug based on AI

Objective :COVID-19 Variants make

high dangerous threat for previous

targeted treatments and recently vaccines

Aim: design novel drug resulted from an

approach active site based to cover all

recently variants

Findings : our compound show affinity

higher than recently used control drug

Future aspects : our approach open

chance to wide ranged AntiViral drug

design

MOPO

MOPO (MonkeyPox database)

We are modeled all MonkeyPox virus protein in one database under-published aimed to included in docken package to fast test of new compounds against all mopo proteins

AI based in- silico drug design for alzaheimer disease

Through the way of in silico drug discovery and organism modeling, many researchers face a problem to test the activity for those active compounds such as anti-oxidant and antibiotics. Problems including time wasting, high costing for assays addition to more information required to ensure the research view. Molecular docking which is one of the most common tools used to solve those problems may also have a computational limitations summarized in time consumption to dock one ligand with a number of proteins to have a profile for interactions. Here, we design an R package that makes a profile for interactions between a query ligand and six main proteins docked for the anti-oxidant activity.

DRUG DESIGN FOR 3CL PROTEASE SARS-COV2 MUTATIONS

Novel antagonest for 7 COVID-19 Variants

COVID-19 Variants make high dangerous threat for previous targeted treatments and recently vaccines , here we design novel drug resulted from an approach active site based to cover all recently variants , our compound show affinity higher than recently used control drug , our approach open chance to wide rang drug design

COVID-19 interaction with Blood systems as statistical analysis and molecular data

Since 2008 it was reported the relationship between SARS-CoV 1-which spread at 2003-and ABO blood group system by Inhibition of the interaction between the SARS-CoV spike protein and its cellular receptor by anti-histo-blood group antibodies .from this point of view many recent studies and analysis made to obtain the interaction between blood biochemistry systems and SARS-CoV2 in host Susceptibility .SARS-CoV2 responsible for today outbreak in whole world by causing COVID 19 Epidemic Which cause above 1million infection today in very short time Here we try to view the possible explanations for this relation

The perception of Puccinia triticina fungal effectors by wheat cystine-rich receptor-like protein kinases (CRKs): Deciphering a layer of wheat defense response

Uses of curcumin: in silico aspect for human targets prediction

The study focuses on identifying natural products with therapeutic potential, specifically investigating Curcumin (from Turmeric) as a promising active compound. Using computational biology (in silico), researchers compared Curcumin's activity against various disease targets, including those related to COVID-19, with conventional pharmaceuticals. The key finding is that Curcumin exhibits higher vital energy than most comparator drugs, supporting its application as an effective natural supplement and synergistic agent to inhibit disease-causing proteins.

In-silico and In-vitro Site-directed Mutagenesis for Smut Resistance in Sugarcane

One promising approach is to improve Class III Chitinase enzyme of Sugarcane which is one of pathogenesis-related (PR) proteins, can catalyze poly chitin, are present in the cell walls of most fungi.

designing of new Aptamer used for nature plant extract

Jun 2023 - Present

EGYPT-US COOPERATION PROGRAM : INNOVATE EGYPT PROGRAM, CALL-3

Grant : Egypt-US Cooperation Program : Innovate Egypt Program VentureWell

Page updated

Google Sites

Report abuse