Publications

Recent selected publications:

1. Generation of control human iPSC line INSTEMi001-A from PBMCs of a healthy Indian donor. Patlolla N, Ponnachan P, Jamora C, Abbey D*. Stem Cell Res. 2023 Jun;69:103112

2. Functional Characterization of Organoids Derived From Irreversibly Damaged Liver of Patients With NASH. McCarron S, Bathon B, Conlon DM, Abbey D, Rader DJ, Gawronski K, Brown CD, Olthoff KM, Shaked A, Raabe TD. Hepatology. 2021 Oct;74(4):1825-1844. 

3. Lipid droplet screen in human hepatocytes identifies TRRAP as a regulator of cellular triglyceride metabolism. Abbey D, Conlon D, Rainville C, Elwyn S, Quiroz-Figueroa K, Billheimer J, Schultz DC, Hand NJ, Cherry S, Rader DJ. Clin Transl Sci. 2021 Jul;14(4):1369-1379. 

4. Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. Shah PP, Lv W, Rhoades JH, Poleshko A, Abbey D, Caporizzo MA, Linares-Saldana R, Heffler JG, Sayed N, Thomas D, Wang Q, Stanton LJ, Bedi K, Morley MP, Cappola TP, Owens AT, Margulies KB, Frank DB, Wu JC, Rader DJ, Yang W, Prosser BL, Musunuru K, Jain R. Cell Stem Cell. 2021 May 6;28(5):938-954.e9.

5. Self-Organizing Human Induced Pluripotent Stem Cell Hepatocyte 3D Organoids Inform the Biology of the Pleiotropic TRIB1 Gene. Abbey D*, Elwyn S, Hand NJ, Musunuru K, Rader DJ. Hepatol Commun. 2020 Jul 8;4(9):1316-1331.

6. An Eye Organoid Approach Identifies Six3 Suppression of R-spondin 2 as a Critical Step in Mouse Neuroretina Differentiation. Takata N, Abbey D*, Fiore L, Acosta S, Feng R, Gil HJ, Lavado A, Geng X, Interiano A, Neale G, Eiraku M, Sasai Y, Oliver G. Cell Rep. 2017 Nov 7;21(6):1534-1549.