2025
2025
Embedded Files
KLK5 and KLK7 drive cervical carcinoma via KLK14-dependent RhoA and NF-κB pathways
Translational Oncology
2025-10 | Journal article
DOI: 10.1016/j.tranon.2025.102488
Contributors: Gabriel Viliod Vieira; Rodrigo Alberto Alves da Silva; Letícia Andrade Costa; João Paulo Bianchi Ximenez; Margarita Lamprou;
Gonçalves Miranda; Vitor de Moura Arrais; Bruna Miyoko Ikenaga de Brito; Elaine Zayas Marcelino da Silva; Bruno Belmonte Martinelli Gomes
et al.
From Genotype to Therapeutic Monitoring: Enhancing Tamoxifen Efficacy in Breast Cancer Treatment
The Journal of Clinical Pharmacology
2025-09-05 | Journal article
DOI: 10.1002/jcph.70103
Contributors: Ana Flávia Mendes Batista; Letícia Penteado Petrolli; Maria Paula Marques Pereira; Adriana Rocha; Jurandyr Moreira de
Andrade; Vera Lucia Lanchote; João Paulo Bianchi Ximenez
Anellovirus abundance as an indicator for viral metagenomic classifier utility in plasma samples
Virology Journal
2025-03-28 | Journal article
DOI: 10.1186/s12985-025-02708-8
Contributors: Gabriel Montenegro de Campos; Luan Gaspar Clemente; Alex Ranieri Jerônimo Lima; Eleonora Cella; Vagner Fonseca; João Paulo Bianchi Ximenez; Milton Yutaka Nishiyama; Enéas de Carvalho; Sandra Coccuzzo Sampaio; Marta Giovanetti et al.
Characterization of Renal OAT3 and Hepatic CYP3A Activities in Pregnant Women with Acute Pyelonephritis Using the Endogenous Biomarker Cortisol and 6β‐Hydroxycortisol
The Journal of Clinical Pharmacology
2025-01-13 | Journal article
DOI: 10.1002/jcph.6186
Contributors: João Paulo Bianchi Ximenez; Jhohann Richard de Lima Benzi; Julia Cristina Colombari; Matheus de Lucca Thomaz; Adriana Rocha; Ana Cláudia Rabelo e Silva; Patrícia Pereira dos Santos Melli; Geraldo Duarte; Vera Lucia Lanchote
2024
2024
Refeeding partially reverses impaired fracture callus in undernourished rats
Frontiers in Endocrinology
DOI: 10.3389/fendo.2024.1385055
Contributors: Iara I. Botega; Patrícia M. S. G. Guedes; João Paulo B. Ximenez; Ariane Zamarioli; José B. Volpon
Nonlinear Mixed‐Effects Model of Z‐Endoxifen Concentrations in Tamoxifen‐Treated Patients from the CEPAM Cohort
Clinical Pharmacology and Therapeutics
DOI: 10.1002/cpt.3238
Contributors: Anna M. Mc Laughlin; Thomas Helland; Fenja Klima; Stijn Koolen; Ron HN van Schaik; R.H.J. Mathijssen; Patrick Neven; Jesse J. Swen; Henk-Jan Guchelaar; Florence Dalenc et al.
Effect of Interindividual Variability in Metabolic Clearance and Relative Bioavailability on Rifampicin Exposure in Tuberculosis Patients with and without HIV Co-Infection: Does Formulation Quality Matter?
Pharmaceutics
DOI: 10.3390/pharmaceutics16080970
Contributors: Glauco Henrique Balthazar Nardotto; Elin Svensson; Bollela VR; Bollela V; Adriana Rocha; Svetoslav Nanev Slavov; Joao Paulo Bianchi Ximenez; Oscar Della Pasqua; Vera Lucia Lanchote
Intestinal P‐gp activity is reduced in postmenopausal women under breast cancer therapy
Clinical and Translational Science
DOI: 10.1111/cts.13713
Contributors: Joao Paulo Bianchi Ximenez; Jurandyr Andrade; Adriana Rocha; Eduardo Barbosa Coelho; Guilherme Suarez-Kurtz; Vera Lucia Lanchote
2023
2023
Development of an Air-assisted Dispersive Liquid-Liquid Microextraction Method as a Valuable Biomonitoring Tool for Exposure Assessment of Phthalates
Brazilian Journal of Analytical Chemistry
DOI: 10.30744/brjac.2179-3425.ar-91-2023
Contributors: Bruno Rocha; Matheus Gallimberti; Marilia Souza; Joao Paulo Bianchi Ximenez; Anderson Martino-Andrade; Jose L Domingo; Fernando Barbosa Jr
Metabarcoding approach to identify bacterial community profiling related to nosocomial infection and bacterial trafficking-routes in hospital environments.
Journal of toxicology and environmental health. Part A
DOI: 10.1080/15287394.2023.2243978
PMID: 37565650
Contributors: Gimenes de Castro B; Mari Fredi B; Dos Santos Bezerra R; Alcantara QA; Milani Neme CE; Mascarelli DE; Carvalho Tahyra AS; Dos-Santos D; Nappi CR; Santos de Oliveira F et al.
An eco-friendly sample preparation procedure based on air-assisted liquid-liquid microextraction for the rapid determination of phthalate metabolites in urine samples by liquid chromatography-tandem mass spectrometry.
Talanta
DOI: 10.1016/j.talanta.2023.124974
PMID: 37494769
Contributors: Alves Rocha B; Gallimberti M; Paulo Bianchi Ximenez J; Giovana Basso C; Joel Martino-Andrade A; Martin Koch H; Augusto Calixto L; Barbosa F
Low-intensity pulsed ultrasound partially reversed the deleterious effects of a severe spinal cord injury-induced bone loss and osteoporotic fracture healing in paraplegic rats
Spinal Cord
DOI: 10.1038/s41393-022-00863-1
Contributors: Ariane Zamarioli; Mariana M. Butezloff; João P. B. Ximenez; José B. Volpon
2022
2022
Evolutionary history of the SARS-CoV-2 Gamma variant of concern (P.1): a perfect storm
Genetics and Molecular Biology
DOI: 10.1590/1678-4685-gmb-2021-0309
Contributors: Yuri Yépez; Mariana Marcano-Ruiz; Rafael S Bezerra; Bibiana Fam; João PB Ximenez; Wilson Araujo Silva Jr; Maria Cátira Bortolini
Fundão tailings dam failure in Brazil: Evidence of a population exposed to high levels of Al, As, Hg, and Ni after a human biomonitoring study
Environmental Research
DOI: 10.1016/j.envres.2021.112524
Contributors: Cavalheiro Paulelli, A.C.; Cesila, C.A.; Devóz, P.P.; Ruella de Oliveira, S.; Bianchi Ximenez, J.P.; Pedreira Filho, W.D.R.; Barbosa Jr., F.
Pharmacogenetic predictors of variability in efavirenz pharmacokinetics in an admixed Brazilian HIV cohort
British Journal of Clinical Pharmacology
DOI: 10.1111/bcp.15387
Contributors: Joao Paulo Bianchi Ximenez; Anna Beatriz Ribeiro Elias; Glauco Henrique Balthazar Nardotto; Paulo Feijó Barroso; Bollela VR; Bollela V; Vera Lucia Lanchote; Guilherme Suarez-Kurtz
Potential Health Risk to Brazilian Infants by Polybrominated Diphenyl Ethers Exposure via Breast Milk Intake
International Journal of Environmental Research and Public Health
Contributors: Marilia Souza; Paula Devóz; João Ximenez; Mariana Zuccherato Bocato; Bruno Rocha; Fernando Barbosa Jr
Vibration therapy as an effective approach to improve bone healing in diabetic rats.
Frontiers in endocrinology
DOI: 10.3389/fendo.2022.909317
PMID: 36060973
PMC: PMC9437439
Contributors: Campos MS; Volpon JB; Ximenez JPB; Franttini AP; Dalloul CE; Sousa-Neto MD; Silva RA; Kacena MA; Zamarioli A
Systemic effects of BMP2 treatment of fractures on non-injured skeletal sites during spaceflight
Frontiers in Endocrinology
DOI: 10.3389/fendo.2022.910901
Contributors: Ariane Zamarioli; Gremah Adam; Kevin A. Maupin; Paul J. Childress; Alexander Brinker; Joao P. B. Ximenez; Nabarun Chakraborty; Aarti Gautam; Rasha Hammamieh; Melissa A. Kacena
Urinary levels of monohydroxylated polycyclic aromatic hydrocarbons in Brazilian children and health risk assessment: a human biomonitoring-based study
Environmental Science and Pollution Research
DOI: 10.1007/s11356-022-19212-z
Contributors: Marilia Souza; Bruno Alves Rocha; João Paulo Bianchi Ximenez; Paula Picoli Devóz; Anthony Santana; Andres Dobal Campíglia; Fernando Barbosa
Metavirome composition of Brazilian blood donors positive for the routinely tested blood-borne infections
Virus Research
DOI: 10.1016/j.virusres.2022.198689
Contributors: Rafael dos Santos Bezerra; João Paulo Bianchi Ximenez; Marta Giovanetti; Victoria Simionatto Zucherato; Hellen Tayaná Bitencourt; Ana Zimmermann; Luiz Carlos Júnior Alcantara; Dimas Tadeu Covas; Simone Kashima; Svetoslav Nanev Slavov
2021
2021
CeTF: an R/Bioconductor package for transcription factor co-expression networks using regulatory impact factors (RIF) and partial correlation and information (PCIT) analysis
BMC Genomics
DOI: 10.1186/s12864-021-07918-2
Contributors: Oliveira de Biagi, C.A.; Nociti, R.P.; Brotto, D.B.; Funicheli, B.O.; Cássia Ruy, P.; Bianchi Ximenez, J.P.; Alves Figueiredo, D.L.; Araújo Silva, W.
Dexamethasone for treating SARS-CoV-2 infection: a systematic review and meta-analysis.
Sao Paulo Medical Journal
DOI: 10.1590/1516-3180.2021.0120.r1.30062021
PMID: 34644768
PMC: PMC9634846
Contributors: Ferreto LED; Bortoloti DS; Fortes PCN; Follador F; Arruda G; Ximenez JP; Wendt GW
Microbiome and oral squamous cell carcinoma: a possible interplay on iron metabolism and its impact on tumor microenvironment.
Brazilian journal of microbiology
DOI: 10.1007/s42770-021-00491-6
PMID: 34002353
PMC: PMC8324744
Contributors: Arthur RA; Dos Santos Bezerra R; Ximenez JPB; Merlin BL; de Andrade Morraye R; Neto JV; Fava NMN; Figueiredo DLA; de Biagi CAO; Silva WA
Analysis of the effects of spaceflight and local administration of thrombopoietin to a femoral defect injury on distal skeletal sites.
NPJ microgravity
DOI: 10.1038/s41526-021-00140-0
PMID: 33772025
PMC: PMC7997973
Contributors: Zamarioli A; Campbell ZR; Maupin KA; Childress PJ; Ximenez JPB; Adam G; Chakraborty N; Gautam A; Hammamieh R; Kacena MA
COVID-19: The question of genetic diversity and therapeutic intervention approaches.
Genetics and Molecular Biology
DOI: 10.1590/1678-4685-gmb-2020-0452
PMID: 35421211
PMC: PMC9075701
Contributors: Figueiredo DLA; Ximenez JPB; Seiva FRF; Panis C; Bezerra RDS; Ferrasa A; Cecchini AL; Medeiros AI; Almeida AMF; Ramão A et al.
2020
2020
A Survey Of Parabens In Commercial Baby Wipes From Brazil and Estimation Of Daily Exposure
Química Nova
DOI: 10.21577/0100-4042.20170494
Contributors: Bruno Rocha; Mariana Bocato; Elder Latorraca; João Paulo Ximenez; Fernando Barbosa Jr.
Characterization of Cabernet Sauvignon wines from California: determination of origin based on ICP-MS analysis and machine learning techniques
European food research & technology.
DOI: 10.1007/s00217-020-03480-5
Contributors: da Costa NL; Ximenez JPB; Rodrigues JL; Barbosa F; Barbosa R
The novel coronavirus SARS-CoV-2: From a zoonotic infection to coronavirus disease 2019.
Journal of medical virology
DOI: 10.1002/jmv.26072
PMID: 32470173
PMC: PMC7283665
Contributors: Dos Santos Bezerra R; Valença IN; de Cassia Ruy P; Ximenez JPB; da Silva Junior WA; Covas DT; Kashima S; Slavov SN
Association of Urinary and Blood Concentrations of Heavy Metals with Measures of Bone Mineral Density Loss: a Data Mining Approach with the Results from the National Health and Nutrition Examination Survey.
Biological trace element research
DOI: 10.1007/s12011-020-02150-7
PMID: 32356206
Contributors: Ximenez JPB; Zamarioli A; Kacena MA; Barbosa RM; Barbosa F
Limited Sampling Modeling for Estimation of Phenotypic Metrics for CYP Enzymes and the ABCB1 Transporter Using a Cocktail Approach.
Frontiers in Pharmacology
PMID: 32174823
PMC: PMC7057125
Contributors: Coelho EB; Cusinato DAC; Ximenez JP; Lanchote VL; Struchiner CJ; Suarez-Kurtz G
2019
2019
Hormonal status affects plasma exposure of tamoxifen and its main metabolites in tamoxifen-treated breast cancer patients
BMC Pharmacology and Toxicology
DOI: 10.1186/s40360-019-0358-y
Contributors: Ximenez JPB, de Andrade JM, Marques MP, Coelho EB, Suarez-Kurtz G, Lanchote VL.
Gene expression changes are associated with severe bone loss and deficient fracture callus formation in rats with complete spinal cord injury.
Spinal cord
DOI: 10.1038/s41393-019-0377-y
PMID: 31700148
Contributors: Butezloff MM; Volpon JB; Ximenez JPB; Astolpho K; Correlo VM; Reis RL; Silva RB; Zamarioli A
Post-marketing assessment of generic tamoxifen in Brazilian breast cancer patients.
Basic & clinical pharmacology & toxicology
DOI: 10.1111/bcpt.13368
PMID: 31758654
Contributors: Ximenez JP; Lanchote VL; Bello MA; Iocken FHS; Obadia RCM; de Sousa VP; Suarez-Kurtz G
An overview of the current progress, challenges, and prospects of human biomonitoring and exposome studies.
Journal of toxicology and environmental health. Part B, Critical reviews
DOI: 10.1080/10937404.2019.1661588
PMID: 31543064
Contributors: Bocato MZ; Bianchi Ximenez JP; Hoffmann C; Barbosa F
Undernutrition impairs the quality of growth plate and trabecular and cortical bones in growing rats1.
Acta cirurgica brasileira
DOI: 10.1590/s0102-865020190030000001
PMID: 30892388
PMC: PMC6585893
Contributors: Guedes PMSG; Zamarioli A; Botega II; Silva RABD; Issa JPM; Butezloff MM; Sousa YTCS; Ximenez JPB; Volpon JB
Bone callus formation is highly disrupted by dietary restriction in growing rats sustaining a femoral fracture1.
Acta cirurgica brasileira
DOI: 10.1590/s0102-865020190010000002
PMID: 30785503
PMC: PMC6585920
Contributors: Botega II; Zamarioli A; Guedes PMSG; Silva RABD; Issa JPM; Butezloff MM; Sousa YTCS; Ximenez JPB; Volpon JB
Before 2019
Before 2019
Evaluation of antimicrobial and biological activities of Portland cement associated of AH Plus sealer in different proportions
Revista Salusvita
2014
site: https://secure.unisagrado.edu.br/static/biblioteca/salusvita/salusvita_v33_n3_2014_art_03.pdf
Contributors: Rodrigo Ricci Vivan, Marcela Vicentini Simonetti, Amanda Berton, Vanessa Raquel Greatti, Joao Paulo Ximenez, Leandro de Andrade Holgado, Mariza Akemi Matsumoto, Paulo Henrique Weckwerth, Marco Antonio Hungaro Duarte
New LLLT protocol to speed up the bone healing process-histometric and immunohistochemical analysis in rat calvarial bone defect.
Lasers in medical science
2014
DOI: 10.1007/s10103-014-1580-x
PMID: 24756326
Contributors: Marques L; Holgado LA; Francischone LA; Ximenez JP; Okamoto R; Kinoshita A
Association among H. pylori virulence markers dupA, cagA and vacA in Brazilian patients.
The journal of venomous animals and toxins including tropical diseases
2014
PMID: 24456629
PMC: PMC3922733
Contributors: Pereira WN; Ferraz MA; Zabaglia LM; de Labio RW; Orcini WA; Bianchi Ximenez JP; Neto AC; Payão SL; Rasmussen LT
BLMH and APOE genes in Alzheimer Disease: A possible relation
Advances in Alzheimer's Disease
2013
Contributors: J. P. B. Ximenez, L. T. Rasmussen, W. A. Orcini, R. W. Labio, G. V. Arruda, P. H. F. Bertolucci, M. A. Smith, S. L. M. Payão
Interleukin-8 -251T>A polymorphism and Helicobacter pylori
Arquivos Catarinenses de Medicina
2011
site: https://www.acm.org.br/revista/pdf/artigos/875.pdf
Contributors: Rita de Cássia Fabris, Lucas Trevizani Rasmussen, Agostinho Caleman Neto, Roger Willian de Lábio, Wilson Orcini, João Paulo Bianchi Ximenez, Solange Franzolin, Spencer Luiz Marques Payão
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