Trabalhos publicados

  • Hilfenhaus, G.; Mompeón, A.; Freshman, J.; Prajapati, D.; Hernandez, G. ; Freitas, V.M. ; Ma, F. ; Langenbacher, A.D. ; Mirkov, S. ; Song, D. ; Cho, B-K ; Goo, YA; Pellegrini, M.; Chen, J.-N. ; Damoiseaux, R.; Iruela-Arispe, M.L. . A high-content screen identifies drugs that restrict tumor cell extravasation across the endothelial barrier. Cancer Research v. x, p. canres.3911.2019, 2020.

  • de Assis Lima, M.; da Silva, S. V.; Serrano-Garrido, O.; Hülsemann, M.; dos Santos-Neres, L.; Rodríguez-Manzaneque, J.C.; Hodgson, L. Freitas, V.M. . Metalloprotease ADAMTS-1 decreases cell migration and invasion modulating the spatiotemporal dynamics of Cdc42 activity. Cellular Signalling, v. x, p. 109827, 2020.

  • Lima, M.A.; Silva, S.V.; Jaeger, Ruy G. ; Freitas, V.M. . Progesterone decreases ovarian cancer cells migration and invasion. Steroids, v. x, p. 108680, 2020.

  • Valadão, I.C. ; Ralph, A.C.L. ; Bordeleau, François; Dzik, Luciana ; Borbely, Karen S.C. ; Geraldo, Murilo V. ; Reinhart-King, Cynthia A. ; Freitas, V. M. . High type I collagen density fails to increase breast cancer stem cell phenotype. PeerJ, v. 8, p. e9153, 2020. Link

  • Caires-Dos-Santos L., da Silva S.V., Smuczek B., de Siqueira A.S., Cruz K.S.P., Barbuto J.A.M., Augusto T.M., Freitas V.M., Carvalho H.F., Jaeger R.G. Laminin-derived peptide C16 regulates Tks expression and reactive oxygen species generation in human prostate cancer cells. Journal of Cell Physiology, [Epub ahead of print], 2019. Link

  • Noriega-Guerra, H., Cruz, M. C., Ribeiro, P. R. L., Strnadel, J., Wang, H., Klemke, R. L., Jaeger, R. G. & Freitas, V. M. ADAMTS-1 disrupts HGF/c-MET signaling and HGF-stimulated cellular processes in fibrosarcoma. Experimental Cell Research, v. 363, 2018. Link

  • Freitas, V. M., Hilfenhaus, G. & Iruela-Arispe, M. L. Metastasis of Circulating Tumor Cells: Speed Matters. Developmental cell, v. 45, 2018. Link

  • Silva, E. M. R., Freitas, V. M., Bautz, W. G., de Barros, L. A. P. & Gama de Souza, L. N. da. Immunohistochemical Study of Laminin-332 γ2 Chain and MMP-9 in High Risk of Malignant Transformation Oral Lesions and OSCC. Journal of Oral and Maxillofacial Research, v. 9, 2018. Link

  • Noriega-Guerra, H. & Freitas, V.M. Extracellular Matrix Influencing HGF/c-MET Signaling Pathway: Impact on Cancer Progression. International Journal of Molecular Sciences, v. 19, 2018. Link

  • Amorim, M. G., Valieris, R., Drummond, R. D., Pizzi, M. P., Freitas, V. M., Sinigaglia-Coimbra, R., Calin, G. A., Pasqualini, R., Arap, W., Silva, I. T., Dias-Neto, E. & Nunes, D. N. A total transcriptome profiling method for plasma-derived extracellular vesicles: applications for liquid biopsies. Scientific Reports, v. 7, 2017. Link

  • Ramirez M. I., Amorim M. G., Gadelha C., Milic I., Welsh J. A., Freitas V. M., Nawaz M., Akbar N., Couch Y., Makin L., Cooke F., Vettore A. L., Batista P. X., Freezor R., Pezuk J. A., Rosa-Fernandes L., Carreira A. C., Devitt A., Jacobs L., Silva I. T., Coakley G., Nunes D. N., Carter D., Palmisano G., Dias-Neto E. Technical challenges of working with extracellular vesicles. Nanoscale, v. 10, 2018. Link

  • Buonfiglio, D. C., Ramos-Lobo, A. M., Freitas, V. M., Zampieri, T. T., Nagaishi, V. S., Magalhães, M., Cipolla-Neto, J., Cella, N. & Donato, J. Obesity impairs lactation performance in mice by inducing prolactin resistance. Scientific Reports, v. 6, 2016. Link

  • Lima, M. A., da Silva, S. V. & Freitas, V. M. Progesterone acts via the progesterone receptor to induce adamts proteases in ovarian cancer cells. Journal of Ovarian Research, v. 9, 2016. Link

  • Siqueira, A. S., Pinto, M. P., Cruz, M. C., Smuczek, B., Cruz, K. S. P., Barbuto, J. A. M., Hoshino, D., Weaver, A. M., Freitas, V. M. & Jaeger, R. G. Laminin-111 peptide C16 regulates invadopodia activity of malignant cells through β1 integrin, Src and ERK 1/2. Oncotarget, v. 7, 2016. Link

  • Lima, M. A., dos Santos, L., Turri, J. A., Nonogaki, S., Buim, M., Lima, J. F., de Jesus Viana Pinheiro, J., Bueno de Toledo Osório, C. A., Soares, F. A. & Freitas, V. M. Prognostic Value of ADAMTS Proteases and Their Substrates in Epithelial Ovarian Cancer. Pathobiology, v. 83, 2016. Link

  • Longhi, M. T., Magalhães, M., Reina, J., Freitas, V. M. & Cella, N. EGFR Signaling Regulates Maspin/SerpinB5 Phosphorylation and Nuclear Localization in Mammary Epithelial Cells. PloS One, v. 11, 2016. Link

  • Silva, S. V., Lima, M. A., Cella, N., Jaeger, R. G. & Freitas, V. M. ADAMTS-1 Is Found in the Nuclei of Normal and Tumoral Breast Cells. PloS One, v. 11, 2016. Link

  • Silva, T. A., Smuczek, B., Valadão, I. C., Dzik, L. M., Iglesia, R. P., Cruz, M. C., Zelanis, A., de Siqueira, A. S., Serrano, S. M. T., Goldberg, G. S., Jaeger, R. G. & Freitas, V. M. AHNAK enables mammary carcinoma cells to produce extracellular vesicles that increase neighboring fibroblast cell motility. Oncotarget, v. 7, 2016. Link

  • Leal, M. F., Calcagno, D. Q., Chung, J., Freitas, V. M., Demachki, S., Assumpção, P. P., Chammas, R., Burbano, R. R. & Smith, M. C. Deregulated expression of annexin-A2 and galectin-3 is associated with metastasis in gastric cancer patients. Clinical and experimental medicine, v. 15, 2015. Link

  • de Sousa, G. F.*, Lima, M. A.*, Custodio, D. F., Freitas, V. M. & Monteiro, G. Chemogenomic Study of Carboplatin in Saccharomyces cerevisiae: Inhibition of the NEDDylation Process Overcomes Cellular Resistance Mediated by HuR and Cullin Proteins. PloS One, v. 10, 2015. (co-primeiros autores) Link

  • Falcão, A. S. C., Kataoka, M. S. da S., Ribeiro, N. A. B., Diniz, J. A. P., Alves, S. M., Ribeiro, A. L. R., Siqueira, A. S. de, da Silva, A. L., Ramos, R. T. J., Freitas, V. M., Jaeger, R. G. & Pinheiro, J. J. V. A Novel Cell Line Derived from Pleomorphic Adenoma Expresses MMP2, MMP9, TIMP1, TIMP2, and Shows Numeric Chromosomal Anomalies. PloS One, v. 9, 2014. Link

  • Nery, L. R., Eltz, N. S., Hackman, C., Fonseca, R., Altenhofen, S., Guerra, H. N., Freitas, V. M., Bonan, C. D. & Vianna, M. R. M. R. Brain Intraventricular Injection of Amyloid-β in Zebrafish Embryo Impairs Cognition and Increases Tau Phosphorylation, Effects Reversed by Lithium. PloS One, v. 9, 2014. Link

  • Freitas, V. M., do Amaral, J. B., Silva, T. A., Santos, E. S., Mangone, F. R., Pinheiro, J. de J., Jaeger, R. G., Nagai, M. A. & Machado-Santelli, G. M. Decreased expression of ADAMTS-1 in human breast tumors stimulates migration and invasion. Molecular Cancer, v. 12, 2013. Link