Carlos Frederico Martins Menck
Coordenador
Livre-docência: Lesões em DNA e suas consequências biológicas, Universidade de São Paulo, USP, Brasil
Pós-doutorado: Ciências Biológicas - Institut des Recherches Scientifiques sur le Cancer, IRSC/CNRS, França
Doutorado: Bioquímica - Universidade de São Paulo, USP, Brasil
Graduação: Ciências Biológicas - Universidade de São Paulo, USP, Brasil
ÚLTIMAS publicações:
Rocha, CRR; Rocha, AR; Silva, MM; Gomes, LR; Latancia, MT; Tomaz, MA; Souza, I; Monteiro, LKS; Menck, CFM (2020) Revealing temozolomide resistance mechanisms via genome-wide CRISPR libraries. Cells 9 (12): 2573.
Fuentes-León F, Peres de Oliveira A, Quintero-Ruiz N, Munford V, Satoru Kajitani G, Coimbra Brum A, Schuch AP, Colepicolo P, Sánchez-Lamar A, Menck CFM (2020) DNA Damage Induced by Late Spring Sunlight in Antarctica. Photochem Photobiol. 96: 1215- 1220.
Castro LP, Sahbatou M, Kehdy FSG, Farias AA, Yurchenko AA, de Souza TA, Rosa RCA, Mendes-Junior CT, Borda V, Munford V, Zanardo ÉA, Chehimi SN, Kulikowski LD, Aquino MM, Leal TP, Tarazona-Santos E, Chaibub SC, Gener B, Calmels N, Laugel V, Sarasin A, Menck CFM (2020) The Iberian legacy into a young genetic xeroderma pigmentosum cluster in central Brazil. Mutat Res.- Genetic Toxicology and Environmental Mutagenesis. 852:503164.
Moreno NC, de Souza TA, Garcia CCM, Ruiz NQ, Corradi C, Castro LP, Munford V, Ienne S, Alexandrov LB, Menck CFM (2020) Whole-exome sequencing reveals the impact of UVA light mutagenesis in xeroderma pigmentosum variant human cells. Nucleic Acids Res 48 (4). 1941-1953.
Moreno NC, Garcia CCM, Munford V, Rocha CRR, Pelegrini, AL, Corradi, C, Sarasin, A, Menck CFM (2019) The key role of UVA-light induced oxidative stress in human Xeroderma Pigmentosum Variant cells. Free Radic Biol Med. 131: 432-442.
Gomes LR, Rocha CRR, Martins DJ, Fiore APZP, Kinker GS, Bruni-Cardoso A, Menck CFM (2019) ATR mediates cisplatin resistance in 3D-cultured breast cancer cells via translesion DNA synthesis modulation. Cell Death Dis 10(6): 459.
Paquola ACM, Asif H, Pereira CAB, Feltes BC, Bonatto D, Lima WC, Menck CFM (2018) Horizontal Gene Transfer Building Prokaryote Genomes: Genes Related to Exchange Between Cell and Environment are Frequently Transferred. J Mol Evol 86 (3-4): 190-203 (this work was honored with the cover of that issue).
Munford V, Castro LP, Souto R, Lerner LK, Vilar JB, Quayle C, Asif H, Schuch AP, de Souza TA, Ienne S, Alves FI, Moura LM, Galante PA, Camargo AA, Liboredo R, Pena SD, Sarasin A, Chaibub SC, Menck CFM (2017) A genetic cluster of xeroderma pigmentosum variant patients with two different founder mutations. Br J Dermatol. 176: 1270-1278.
Yagura T, Schuch AP, Garcia CC, Rocha CR, Cestari Moreno N, Angeli JP, Mendes D, Severino D, Bianchini Sanchez A, Di Mascio P, Gennari de Medeiros MH, Menck CFM (2017) Direct participation of DNA in the formation of singlet oxygen and base damage under UVA irradiation. Free Radic Biol Med. 108: 86-93.
Lerner LK, Francisco G, Soltys DT, Rocha CR, Quinet A, Vessoni AT, Castro LP, David TI, Bustos SO, Strauss BE, Gottifredi V, Stary A, Sarasin A, Chammas R, Menck CFM (2017) Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells. Nucleic Acids Res 45(3): 1270-1280.
Quinet A, Martins DJ, Vessoni AT, Biard D, Sarasin A, Stary A, Menck CFM (2016) Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells. Nucleic Acids Res. 44(12): 5717-5731.