Explore how AI can support your studies, clinical thinking, and communication. Learn how to ask the right questions — and think critically about the answers
New to AI?
Start with this PDF handout “The Basics of AI: A Medical Student’s Primer”
GPT-5 brings important updates that make it easier, smarter, and more useful for your studies. Here are the key changes you should know:
Decides when to use quick vs. deep reasoning
No need to write “step-by-step”
Handles up to 400k tokens
Paste entire guidelines or slide packs
Ask it to cite by page/slide
Directly create tables, lists, JSON
Cleaner results for differentials/tests
Reasoning tasks → ask for key assumptions
Direct tasks → just ask plainly
Tool for upgrading old GPT-4 prompts
Tighter, more effective instructions
Warmer, clearer tone by default
Less need for “be friendly/concise”
✨ In short: GPT-5 is better at knowing when to think deeply, can handle huge amounts of text, gives cleaner structured outputs, and requires simpler prompting.
✨ Bottom line: GPT-5 = deeper thinking, bigger memory, cleaner outputs, easier prompts.
AI responses can vary depending on how you phrase your prompt. Small changes in wording often lead to very different explanations, levels of detail, or even teaching styles. This exercise will help you see how prompt design shapes the quality and usefulness of AI output.
Prompt 1: “Explain pancytopenia.”
Prompt 2: “You are a hematology tutor. Explain pancytopenia for 2nd-year medical students in ≤150 words. Focus on causes from bone marrow failure vs peripheral destruction. End with 3 self-test questions.”
👉 Compare outputs and reflect: Which is clearer? Which is more useful for your level? What might you change in the prompt to improve it further?
Formula: WHO + WHAT + CONTEXT + FORMAT + DEPTH
Are you spending more time creating study materials than actually studying them? If you're a medical student drowning in textbooks and struggling to create effective flashcards, this comprehensive guide will revolutionize your approach to medical education.
In just 30 minutes, you'll be generating hundreds of high-quality medical flashcards that would have taken you hours to create manually.
Recommended prerequisites: This course lightly covers the foundational AI Fluency concepts. However, for deeper understanding, participants should complete AI Fluency: Framework & Foundations before beginning this student-focused curriculum. It is also recommended that learners have access to an AI chat tool for hands-on practice. Examples in this course will use Claude.ai, but any chatbot will work.
Build a 2-week revision plan for hematology with daily focus topics.
Explain the coagulation cascade in ≤200 words for a 2nd-year medical student. Use a step-by-step flow
Summarize the differences between AML and ALL in a comparison table with at least 3 key features.
“Teach me the CRAB criteria for multiple myeloma using an easy-to-remember mnemonic
Create 5 multiple-choice questions on iron deficiency anemia with answers and short explanations.”
“Make a 10-question true/false quiz on the pathophysiology of CLL.”
“Give me 3 short clinical vignettes on thrombocytopenia with the most likely diagnosis.”
Test me on coagulation pathways using flashcard-style questions
Generate a list of common exam questions on acute leukemia.
Give me 3 possible differential diagnoses for isolated thrombocytopenia. Rank them by likelihood in a 25-year-old patient. Explain your reasoning
You are a hematology tutor. I will give you lab results — CBC: Hb 8 g/dL, WBC 3,200/µL, Platelets 90,000/µL. Suggest next diagnostic steps, and explain why
I read this sentence: ‘Anemia in CLL is often autoimmune.’ Critically evaluate this statement and explain in ≤100 words when it is true and when it is misleading
Help me generate a differential for lymphadenopathy
Follow-up: "Ask me questions to refine the differential."
What questions should I ask in a history for unexplained anemia?
Act as a tutor: quiz me on causes of leukocytosis
Act as a patient’s spouse asking: ‘Is this leukemia my partner’s fault?’ Help me practice a compassionate, professional response.
Simulate a parent who asks why their child needs a bone marrow biopsy. Give emotional as well as rational concerns for me to address
Role-play as a patient who refuses chemotherapy because of fear of side effects. I will practice responding with empathy.
How would you explain 'acute leukemia' in plain Greek for a patient handout (≤120 words). Add 3 FAQs with one-sentence answers. If uncertain, state the uncertainty and what information would reduce it.”
Translate this discharge summary into plain English.
Write a short script to explain 'cytopenia' to a patient's caregiver.
Summarize the side effects of [chemotherapy] for a patient leaflet.
By Dr. Eleftheria Hatzimichael
This toolkit is designed to help medical students and physicians make the most of Artificial Intelligence tools like ChatGPT, Gemini, and Perplexity. It provides ready-to-use prompts across clinical practice, research, education, and personal development—empowering healthcare professionals to ask better questions, think critically, and save time.
With over 60 curated use cases, the toolkit covers:
📖 Clinical Practice: generating differential diagnoses, drafting patient education materials, summarizing guidelines.
🔬 Research: literature reviews, clinical trial design brainstorming, data interpretation.
🎓 Education: teaching aids, quiz generation, role-playing with virtual patients.
🌱 Well-being & Growth: reflective writing, leadership development, mindfulness practices.
This resource encourages responsible and ethical use of AI in medicine, aligning with academic integrity and patient privacy standards.
👉 Download the toolkit and start experimenting with prompts to see how AI can enhance your professional and personal journey.
CBC: Platelets 950,000/μL, Hb 14.2 g/dL, WBC 7,800/μL
CRP: Elevated
Recent hx: Nephrectomy for RCC 2 months ago
JAK2 mutation: Pending
Peripheral smear: Platelets appear large, some clumping
No symptoms
Prompt:
“You are a hematologist. A patient presents with isolated thrombocytosis. Please give a structured differential diagnosis (reactive vs clonal), ranked by likelihood based on available data.”
Prompt:
“What tests should be performed to differentiate reactive from primary thrombocytosis? Include genetic and inflammatory workup.”
Prompt:
“What further data or results (labs, history, or genetic tests) would shift the differential toward a myeloproliferative neoplasm?
Data given:
CBC values, blood smear image (or description), marrow summary, cytogenetics snippet.
Prompt:
"You are a hematologist. Based on the following case summary, generate a differential diagnosis for pancytopenia. Present it in structured bullet points ranked by likelihood. Use only the data provided."
→ Output: AI-generated differential with reasoning.
Prompt:
"What tests would you recommend next and why? Explain the diagnostic reasoning behind the testing sequence."
→ Output: Suggested testing steps and rationale.
Prompt:
"What additional missing data would most influence your top diagnostic choice, and how?"
→ Output: Statement of diagnostic uncertainty and next steps.
CBC: Platelets 28,000/μL, Hb 13.6 g/dL, WBC 6,100/μL
Peripheral smear: Large platelets, no schistocytes
Recent history: Viral illness 2 weeks ago
Medications: Ibuprofen for 5 days
No bleeding symptoms
Prompt:
“You are a hematologist. Based on this case of isolated thrombocytopenia with normal hemoglobin and WBCs, provide a differential diagnosis in structured bullet points, ranked by likelihood. Consider morphology and history.”
Prompt:
“What initial diagnostic tests should be ordered and why? Justify each based on the suspected diagnoses.”
Prompt:
“What data would be most helpful in refining your top diagnostic suspicion? How would your interpretation change with those results?”
Get Organized AI Responses Every Time
Stop wasting time with messy ChatGPT answers. This free guide teaches you JSON prompting - the simple formatting technique that gets you structured, study-ready responses for any medical topic.
Perfect for creating:
Organized patient case studies
Structured differential diagnoses
Consistent flashcards and study guides
Professional-quality notes
AI Tools for Medical Students (PDF)
Knowledge becomes meaningful when it returns to people
Page curated by: Eleftheria Hatzimichael, MD, PhD