Eleftheria Hatzimichael, MD, PhD

Associate Professor of Haematology

Faculty of Medicine, School of Health Sciences, University of Ioannina

Short CV

Eleftheria Hatzimichael, MD, PhD (born 1975) is a Haematologist, with a strong background and research activities in epigenetics and translational research. and currently an Associate Professor of Haematology, in the Faculty of Medicine, School of Health Sciences, University of Ioannina Greece. She graduated from the School of Medicine, University of Ioannina in 1998 and was trained in Haematology at St. Bartholomew’s Hospital, Barts and the London Trust, London, UK and the Department of Haematology, University Hospital of Ioannina, Ioannina, Greece. For her achievements on 2011, she was awarded a prestigious early-carrier one-year fellowship from the Hellenic Society of Haematology Foundation to work with Dr Isidore Rigoutsos as a Visiting Scientist at the Computational Medicine Centre, Jefferson Medical College, Thomas Jefferson University, US, in the field of the non-coding human genome by computational and experimental approaches. She has also received the prestigious Clinical Research Training in Haematology award 2016-2017 by the European Haematology Association, 9-month-long unique training and mentoring experience focused on clinical research in Europe, with a global scope. 

She is the PI of more than 30 Phase II-IV clinical trials and has served as a subinvestigator in more than 25 phase I-III clinical trials and as a reviewer for more than 27 journals. She is a member of the Associate Editorial Board of the American Journal of Blood Research and member of the Editorial Board of Diseases (section Oncology), Associate Editor in Frontiers in Medicine (section Hematology) and a member of the Hellenic Society of Haematology, the Greek Myeloma Study Group (GMSG), The Greek (Hellenic) MDS Group, the American Society of Hematology, the European Cancer Research Association, and the European Haematology Association. She is also the Secretary of the Steering Committee of the Scientific Department of Myelodysplastic Syndromes and Marrow Failure of the Hellenic Society of Hematology, 2022-2023, 2024-2025, and a Member of the Board of Directors of the Hellenic Society of Hematology, 2022-2024.

She has more than 130 papers in peer-reviewed journals with an h-index of 32 (source Scopus). 

Medical education

1992-1998 Medical School of Ioannina, University of Ioannina, Ioannina, Greece

Jul 1998 Medical License  9894/ 27-7-1998                                           

Dec 2008   PhD, Medical School of Ioannina, University of Ioannina, Greece

Title of thesis: “Study of the expression and clinical significance of cyclins and the methylation status of cyclin inhibitors in hematological malignancies”

Education relevant to clinical research

Reviewer in 31 Journals


Full list here

Invited Speaker in Greek and International Conferences

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Publications

137 publications in peer-reviewed journals

Full list of publications here

10 most cited papers

1. Article  •  Open access 320 Citations

 

Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- And tissue-specific microRNAs. Londina, E., Lohera, P., Telonis, A.G., ...Fortina, P., Rigoutsos, I. Proceedings of the National Academy of Sciences of the United States of America, 2015, 112(10), pp. E1106–E1115

 

2.    Article  •  Open access 250 Citations

 

MEG3 imprinted gene contribution in tumorigenesis. Benetatos, L., Vartholomatos, G., Hatzimichael, E. International Journal of Cancer, 2011, 129(4), pp. 773–779

 

3.    Review 216 Citations

 

The microRNAs within the DLK1-DIO3 genomic region: Involvement in disease pathogenesis. Benetatos, L., Hatzimichael, E., Londin, E., ...Rigoutsos, I., Briasoulis, E. Cellular and Molecular Life Sciences, 2013, 70(5), pp. 795–814

 

4.    Article 137 Citations

 

CpG methylation analysis of the MEG3 and SNRPN imprinted genes in acute myeloid leukemia and myelodysplastic syndromes. Benetatos, L., Hatzimichael, E., Dasoula, A., ...Georgiou, I., Bourantas, K.L. Leukemia Research, 2010, 34(2), pp. 148–153

 

5.    Article  •  Open access 137 Citations

 

The role of immune suppression and HHV-8 in the increasing incidence of HIV-associated multicentric Castleman's disease. Powles, T., Stebbing, J., Bazeos, A., ...Gazzard, B., Bower, M. Annals of Oncology, 2009, 20(4), pp. 775–779

 

6.    Article  •  Open access 130 Citations

 

Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma. Syed, N., Langer, J., Janczar, K., ...Roncaroli, F., Crook, T. Cell Death and Disease, 2013, 4(1)

 

7.    Review  •  Open access 115 Citations

Hematopoietic stem cell transplantation. Hatzimichael, E., Tuthill, M.

Stem Cells and Cloning: Advances and Applications, 2010, 3(1), pp. 105–117

 

8.    Article  •  Open access 108 Citations

 

Serum interleukin (IL)-1, IL-2, sIL-2Ra, IL-6 and thrombopoietin levels in patients with chronic myeloproliferative diseases. Panteli, K.E., Hatzimichael, E.C., Bouranta, P.K., ...Stebbing, J., Bourantas, K.L. British Journal of Haematology, 2005, 130(5), pp. 709–715

  

9.    Article  •  Open access 104 Citations

 

Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis. Delage, B., Luong, P., Maharaj, L., ...Chen, L.-T., Szlosarek, P.W. Cell Death and Disease, 2012, 3(7), e342

 

10. Review 93 Citations

The role of cytokines in sickle cell disease. Makis, A.C., Hatzimichael, E.C., Bourantas, K.L. Annals of Hematology, 2000, 79(8), pp. 407–413

 

 


Author Metrics


Citations

3,628

Citations by 3,343 documents


h-index 32


Primary Investigator in 30 Clinical Trials

Full list here