We are able to indentify and quantify the main Avenanthramides present in natural extracts of Oat or Oat-containing products via HPLC/MS method.

Our group published several papers in collaboration on Oat extracts and Avenanthramides:

• Scarpa, E. S.; Antonini, E.; Palma, F.; Mari, M.; Ninfali, P. "Antiproliferative activity of vitexin-2-O-xyloside and avenanthramides on CaCo-2 and HepG2 cancer cells occurs through apoptosis induction and reduction of pro-survival mechanisms" Eur. J. Nutr. 2018, 57, 1381-1395. Link
• Scarpa, E. S.; Mari, M.; Antonini, E.; Palma, F.; Ninfali, P. "Natural and synthetic avenanthramides activate caspases 2, 8, 3 and downregulate hTERT, MDR1 and COX-2 genes in CaCo-2 and Hep3B cancer cells" Food Funct. 2018, 9, 2913-2921. Link
• Ninfali, P.; Mari, M.; Meli M. A.; Roselli, C.; Antonini, E. "In vitro bioaccessibility of Avenanthramides in cookies made with malted oat flours" Int. J. Food. Sci. Technol. 2019, 54, 1558-1565. Link

GLUOS is an innovative and emerging science-based university spin-off, in the field of anti-oxidant and anti-inflammatory chemicals.

GLUOS offers a novel and green technology for the production at industrial level of a new and efficient anti-oxidant, anti-inflammatory, anti-influenza and anti-viral agent called C4-Glutathione (C4-GSH).

GLUOS business idea deals with production and marketing of C4-Glutathione, obtained through its innovative, highly efficient and low-cost process.

The team is composed by young researchers and professors in Chemical Sciences from University of Urbino Carlo Bo, covering all the necessary skills.