Neuromuscular Plasticity for Natural Motor Rehabilitation (INcEPTION) Laboratory

Our laboratory integrates cutting-edge methodologies to investigate fundamental questions in a broad range of neuromuscular physiology topics, including motor control, neural plasticity, and neuromuscular disorders.

By combining electrophysiological recordings and advanced signal processing methods, we strive to gain a comprehensive understanding of the neuromuscular control in different applications.

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What we investigate

In 2022, Prof. Negro was awarded a Consolidator Grant by the European Research Council, securing funding for the research project INcEPTION. The project is dedicated to advancing innovative methods for estimating neural connectivity patterns through high-density surface electromyograms decomposition. The project also involves inducing reorganization in the connectivity of motor neuron populations by employing magnetic and electrical stimulation of cortical and sensory pathways. INcEPTION aims to achieve these purposes through three objectives that drive the main research projects of our laboratory:

I: Robust estimation of neural marker of motoneuron connectivity

II: Induction of persistent neural signatures of correlated motoneuron activity

III: Robust framework for the concurrent estimation and stimulation of neural patters