Some publications involving our group at UMN

PUBLICATIONS

2025

Bohm EK, Castañeda D, Lu Q, Cameron MD, and Aliota MT

Zika virus-induced fetal demise is triggered by strain- and dose-specific RLR-driven activation of the interferon response in the decidua, placenta, and fetus in Ifnar1−/− mice

Journal of Virology, e0066625.

Lange RE*, Pritchard JC*, Jaeger AS, Bold TD, White JL, Dean AB, Hull RC, St. George K, Dupuis AP, Aliota MT*†, and Ciota AT*

Differential Virulence and Host-Specific Fitness of Regionally Distinct Human-Derived Powassan Virus Lineage 2 Strains

American Journal of Tropical Medicine and Hygiene, tpmd240776.

Li A, Coffey LL, Mohr EL, Raper J, Chahroudi A, Ausderau KK, Aliota MT, Friedrich TC, Mitzey AM, Koenig MR, Golos TG, Jaeger HK, Roberts VHJ, Lo JO, Smith JL, Hirsch AJ, Streblow DN, Newman CM, O’Connor DH, Van Rompay KKA, Adams Waldorf KA

Role of non-human primate models in accelerating research and developing countermeasures against Zika virus infection

The Lancet Microbe, online ahead of print.

2024

Klontz EH, Chowdhury N, Holbrook N, Solomon IH, Telford SR 3rd, Aliota MT, Vogels CBF, Grubaugh ND, Helgager J, Hughes HR, Velez J, Piantadosi A, Chiu CY, Lemieux J, Branda JA.

Analysis of Powassan Virus Genome Sequences from Human Cases Reveals Substantial Genetic Diversity with Implications for Molecular Assay Development

Viruses, 16(11):1653

Castañeda D, Isaac EJ, Schnieders BP, Kautz T, Romanski MC, Morre SA, and Aliota MT

Absence of SARS-CoV-2 in wildlife of northeastern Minnesota and Isle Royale National Park

Zoonoses and Public Health, 71(6):744-747

Singh T, Miller IG, Venkatayogi S, Webster H, Heimsath HJ, Eudailey JA, Dudley DM, Kumar A, Mangan R, Thein A, Aliota MT, Newman CM, Mohns MS, Breitbach ME, Berry M, Wiehe K, O’Connor DH, and Permar SR

Prior dengue virus serotype 3 infection modulates subsequent plasmablast responses to Zika virus infection in rhesus macaques

mBio, 15(3):e0316023

2023

Ramuta MD, Minor NR, Stauss MR, Harwood OE, Brakefield SF, Alberts A, Vuyk WC, Bobholz MJ, Rosinski JR, Wolf S, Lund M, Mussa M, Beversdorf LJ, Aliota MT, O’Connor SL, and O’Connor DH

Metagenomic sequencing detects human respiratory and enteric viruses in air samples collected from congregate settings

Scientific Reports, 13(1):21398

Krabbe NP, Razo E, Abraham HJ, Spanton RV, Shi Y, Bhattacharya S, Bohm EK, Pritchard JC, Weiler AM, Mitzey AM, Eickhoff JC, Sullivan E, Tan JC, Aliota MT, Friedrich TC, O’Connor DH, Golos TG, and Mohr EL

Control of maternal Zika virus infection during pregnancy is associated with lower antibody titers in a macaque model

Frontiers in Immunology, 14:1267638

Jaeger AS, Marano J, Riemersma KK, Castañeda D, Pritchard E, Pritchard JC, Bohm EK, Bacenzas JJ, O’Connor SL, Weger-Lucarelli J, Friedrich TC, and Aliota MT

Gain without pain: adaptation and increased virulence of Zika virus in vertebrate host without fitness cost in mosquito vector

Journal of Virology, e0116223.

Boehm EC*, Jaeger AS*, Ries HJ*, Castañeda D, Weiler AM, Valencia CC, Weger-Lucarelli J, Ebel GD, O’Connor SL, Friedrich TC, Zamanian M, and Aliota MT

Wolbachia-mediated resistance to Zika virus infection in Aedes aegypti is dominated by diverse transcriptional regulation and weak evolutionary pressures

PLOS Neglected Tropical Diseases, 17(10): e0011674.

Jaeger AS, Crooks CM, Weiler AM, Bliss MI, Rybarczyk S, Richardson A, Einwalter M, Peterson EM, Capuano S III, Barkhymer A, Becker JT, Greene JT, Freedman TS, Langlois RA, Friedrich TC, and Aliota MT.

Primary infection with Zika virus provides one-way heterologous protection against Spondweni virus infection in rhesus macaques

Science Advances, 9(26).

Koenig MR, Mitzey AM, Morgan TK, Zeng X, Simmons HA, Mejia A, Leyva Jaimes F, Keding LT, Crooks CM, Weiler AM, Bohm EK, Aliota MT, Friedrich TC, Mohr EL, and Golos TG.

Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an African-lineage Zika virus

PLOS ONE, 18(5):e0284964.

Rosinski JR, Raasch LE, Tiburcio PB, Breitbach ME, Shepherd PM, Yamamoto K, Razo E, Krabbe NP, Bliss MI, Richardson AD, Einwalter MA, Weiler AM, Sneed EL, Fuchs KB, Zeng X, Noguchi KK, Morgan TK, Alberts AJ, Antony KM, Kabakov S, Ausderau K, Bohm EK, Pritchard JC, Spanton RV, Ver Hoove JN, Kim CBY, Nork TM, Katz AW, Rasmussen CA, Hartman A, Mejia A, Basu P, Simmons HA, Eickhoff JC, Friedrich TC, Aliota MT, Mohr EL, Dudley DM, O’Connor DH, and Newman CM

Frequent first-trimester pregnancy loss in rhesus macaques infected with African-lineage Zika virus.

PLOS Pathogens, 19(3):e1011282.

2022

Ramuta MD, Newman CM, Brakefield SF, Stauss MR, Wiseman RW, Kita-Yarbro A, O’Connor EJ, Dahal N, Lim A, Poulsen KP, Safdar N, Marx JA, Accola MA, Rehrauer WM, Zimmer JA, Khubbar M, Beversdorf LJ, Boehm EC, Castañeda D, Rushford C, Gregory DA, Yao JD, Bhattacharyya S, Johnson MC, Aliota MT, Friedrich TC, O’Connor DH, and O’Connor SL

SARS-CoV-2 and other respiratory pathogens are detected in continuous air samples from congregate settings

Nature Communications, 13:4717

Raasch LE, Yamamoto K, Newman CM, Rosinski JR, Shepherd PM, Razo E, Crooks CM, Bliss MI, Breitbach ME, Sneed EL, Weiler AM, Zeng X, Noguchi KK, Morgan TK, Fuhler NA, Bohm EK, Alberts AJ, Havlicek SJ, Kabakov S, Mitzey AM, Antony KM, Ausderau KK, Mejia A, Basu P, Simmons HA, Eickhoff JC, Aliota MT, Mohr EL, Friedrich TC, Golos TG, O’Connor DH and Dudley DM

Fetal loss in pregnant rhesus macaques infected with high-dose African-lineage Zika virus

PLoS Neglected Tropical Diseases, 16(8): e0010623

Dudley DM, Koenig MR, Stewart LM, Semler MR, Newman CM, Shepherd PM, Yamamoto K, Breitbach ME, Schotzko ML, Kohn S, Antony KM, Qui H, Tunga P, Anderson DM, Guo W, Dennis M, Singh T, Rybarczyk S, Weiler AM, Razo E, Mitzey A, Zeng X, Eickhoff JC, Mohr EL, Simmons HA, Fritsch MK, Meija A, Aliota MT, Friedrich TC, Golos TG, Kodihalli S, Permar SR, and O’Connor DH

Human immune globulin treatment controls Zika viremia in pregnant rhesus macaques

PLoS ONE, 17(7):e0266664

Puskarich MA, Ingraham NE, Merck LH, Driver BE, Wacker DA, Page Black L, Jones AE, Fletcher CV, South AM, Murray TC, Lewandowski C, Farhat J, Benoit JL, Byrne D, Hall A, Reilkoff RA, Biros MH, Cherabuddi K, Chipman JG, Schacker TW, Guirgis FW, Voelker HT, Koopmeiners JS, and Tignanelli TJ; Angiotensin Receptor Blocker Based Lung Protective Strategies for Inpatients With COVID-19 (ALPS-IP) Investigators: Nelson AC, Hall A, Wright D, Reilkoff RA, Bold T, Beckman K, Langlois RA, Aliota MT, Galbriath J, Beyer M, Salmen C, Byrne D, Roberts B.

Efficacy of Losartan in Hospitalized Patients With COVID-19-Induced Lung Injury: A Randomized Clinical Trial

JAMA Network Open, 5(3):e222735

Peinado SA, Aliota MT, Blitvich BJ, and Bartholomay LC.

Biology and Transmission Dynamics of Aedes flavivirus

Journal of Medical Entomology, online ahead of print