Murphy Group

Consequences of altered Cacna1c and Cacna1d expression levels on CaV1.2 and CaV1.3 activity

Studied consequences of risk alleles associated with neuropsychiatric disorders and memory impairment by functionally assaying voltage-gated calcium channel activity of genetically manipulated mouse models

Calcium activity of human induced pluripotent stem cell (iPSC)-derived neurons from patients with bipolar disorder

Analyzed calcium imaging data of cells derived from patients with a risk allele associated with bipolar disorder to determine neurophysiological implications of the mutation