Ocular Biomechanics
Dr. Alan Argento, Dr. Sayoko Moroi and Dr. Guan (Gary) Xu
This is joint research between Dr. Alan Argento, Dr. Sayoko Moroi and Dr. Guan Xu. We are working on projects focused on the biomechanics and multispectral photoacoustic imaging of the anterior chamber.
One representative study in our lab is to resolve the anatomy and compute biomechanical behaviors of tissue components, specifically the aqueous veins and surrounding perilimbal sclera. The work involves varying intraocular pressure to induce deformation of the tissue components. The deformation of each component is quantified from the images, tracked and used to determine 3D strains by finite element methods. These quantitative measurements assist in understanding the biomechanical characteristics of the tissue components, their interactions, and roles in disease, which is glaucoma in this case.
Funding Support: The Glaucoma Foundation, National Science Foundation CMMI 1760291, Kellogg Eye Center startup fund.
Team
Dr. Amanda Bicket, Assistant Professor
Dr. Wonsuk Kim, Associate Research Scientist
Linyu Ni, PhD Candidate
Erik Krawczyk, Research Assistant
Alexus Warchock, Research Assistant