Preprint/In review

Underline indicates work by a trainee. An asterisk indicates equal contribution.

1. Fu M, Faul JD, Jin Y, Ware EB*, Bakulski KM*. 2022. Mendelian randomization of smoking behavior for cognitive status among older Americans. medRxiv doi: https://doi.org/10.1101/2019.12.11.19014522 In review. GitHub repository. 

2. Ladd-Acosta C, Andrews SV, Bakulski KM, Feinberg JI, Tryggvadottir R, Yao R, Croen LA, Hertz-Picciotto I, Newschaffer CJ, Salafia CM, Arking DE, Feinberg AP, Hansen KD, Fallin MD. 2022. Placenta DNA methylation at ZNF300 is associated with fetal sex and placental morphology. bioRxiv doi: https://www.biorxiv.org/content/10.1101/2021.03.04.433985v1 In review.

3. Campbell KA, Colacino JA, Puttabyatappa M, Hammoud SS, Domino SE, Dolinoy DC, Goodrich J, Loch-Caruso R, Padmanabhan V, Bakulski KM. 2022. Deconvolution of an epidemiologic preeclampsia dataset reveals cell type proportion differences that largely drive gene expression differences. In review. https://biorxiv.org/cgi/content/short/2021.07.29.454041v2. GitHub repository. 

4. Monasso G, Hoang T, Mancano G, Fernández-Barrés S, Dou JF, Jaddoe V, Page C, Johnson L, Bustamante M, Bakulski KM, Håberg S, Ueland P, Battram T, Küpers L, Sunyer J, Nystad W, Heil S, Schmidt RJ, Vrijheid M, Sharp G, London SJ, Felix J. 2022. A meta-analysis of epigenome-wide association studies on pregnancy vitamin B12 concentrations and offspring DNA methylation: In review.

5. Bakulski KM, Blostein FA, London SJ. 2022. Linking prenatal environment to lifetime health with epigenome-wide association studies. In review.

6. Harris SM, Su AL, Dou JF, Loch-Caruso R, Elkin ER, Bakulski KM. 2022. Placental cell conditioned media modifies hematopoietic stem cell transcriptome in vitro. In review. GitHub repository.

7. Middleton LYM, Nguyen VK, Dou J, Park SK, Colacino JA, Bakulski KM. Environmental chemical-wide associations with immune biomarkers in the US: A cross-sectional analysis. In review. https://www.medrxiv.org/content/10.1101/2022.03.22.22272789v2

8. Wang X, Bakulski KM, Park SK. 2022. Associations of healthy lifestyle and socioeconomic status with cognitive function in U.S. older adults. In review.

9. Ruehlmann AK, Sammallahti S, Cortés Hidalgo AP, Bakulski KM, Binder EB, Campbell ML, Caramaschi D, Cecil C, Colicino E, Cruceanu C, Czamara D, Dieckmann L, Dou J, Felix JF, Frank J, Håberg SE, Herberth G, Hoang TT, Houtepen LC, Hüls A, Koen N, London SJ, Magnus MC, Mancano G, Mulder RH, Räikkönen K, Röder S, Schmidt RJ, Send TS, Sharp G, Streit F, Tuhkanen J, Witt SH, Zenclussen AC, Zhang Y, Zillich L, Wright R, Lahti J, Brunst KJ, 2022. Epigenome-wide meta-analysis of prenatal maternal stressful life events and newborn DNA methylation. In review.

10. Higgins C, Ware EB, Kobayashi LC, Fu MZ, Hicken M, Zawistowski Z, Mukherjee B, Bakulski KM. 2022. Circulating cystatin-C is associated with dementia in a racial and ethnically diverse cohort: An interaction decomposition analysis. In review. https://www.medrxiv.org/content/10.1101/2022.09.09.22279743v1

11. Dou JF, Bakulski KM, Guo K, Hur J, Zhou L, Saez-Atienzar S, Stark AR, Chia R, García-Redondo A, Rojas-García R, Vázquez-Costa JF, SantiagonRF, Bandres-Ciga S, Gómez-Garre P, Periñán MT, Mir P, Pérez-Tur J, Cardona F, Menendez-Gonzalez M, Riancho J, Borrego-Hernández D, Galán-Dávila L, Ceberio JI, Pastor P, Spanish Neurological Consortium, Traynor BJ, Feldman EL, Goutman SA, & Spanish Neurological Consortium. 2022. Cumulative genetic risk and C9orf72 repeat status independently associate with ALS status in two case-control studies. medRxiv. https://doi.org/10.1101/2022.10.27.22281377

12. Kadalayil L, Alam MZ, White CH, Ghantous A, Walton E, Gruzieva O, Merid SK, Kumar A, Roy RP, Solomon O, Huen K, Eskenazi B, Rzehak P, Grote V, Koletzko B, Langhendries J-P, Verduci E, Ferre N, Gao L, Guan W, Zeng X, Schisterman EF, Dou JF, Bakulski KM, Feinberg JI, Soomro MH, Annesi-Maesano I, Pesce G, Popovic M, Plusquin M, Vafeiadi M, Roumeliotaki T, Langie SAS, Standaert A, Allard C, Perron P, Bouchard L, van Meel ER, Felix JF, Jaddoe VWV, Yousefi PD,, Nøhr EA, Relton CL, Tobi EW, Starling AP, Yang IV, Llambrich M, Santorelli G, Lepeule J, Salas LA, Bustamante M, Ewart SL, HZhang H, Karmaus W, Röder S, Zenclussen AC, Jin J Nystad W, Page CM, Magnus M, Jima DD, Hoyo C, Maguire RL, Kvist T, Czamara D, Räikkönen K, Gong T, Ullemar V, Rifas-Shiman SL, Oken E, Sharp GC, Melén E, Wiemels JL Holland N, Gruszfeld D, Breton CV, Yeung E, Fallin MD, Baiz N, Isaevska E, Nawrot TS, Kogevinas M, Nelen V, Duijts L, Sørensen TIA, Ramlau-Hansen CH, Steegers-Theunissen RPM, Dabelea D, Grazuleviciene R, Sunyer J, Arshad H, Herberth G, London SJ, Haberg SE, Murphy SK, Lahti J, Karlsson R, Almqvist C,, Hivert M-F, Silver MJ, Rezwan FI, Holloway JW. Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude. In review.

13. Heiss JA, Bakulski KM, Thyagarajan B, Crimmins EM, Faul JD, Fisher JD, Just AC. Computational deconvolution of fifteen leukocyte subtypes from DNA methylation microarrays trained on flow cytometry data in the Health and Retirement Study. In review. https://www.biorxiv.org/content/10.1101/2022.11.28.518190v1 

14. Wang X, Bakulski KM, Fansler S, Mukherjee B, Park SK. Improving the prediction of death from cardiovascular causes with multiple risk markers. In review.

15. Dou J, Thangaraj SV, Puttabyatappa M, Elangovan VR, Bakulski KM*, Padmanabhan V*. Developmental Programming: adipose depot-specific regulation of non-coding RNAs and their relation to coding RNA expression in prenatal testosterone and prenatal bisphenol-A -treated female sheep. In review. 

16. Blostein F, Zou T, Bhaumik D, Salzman E, Bakulski KM, Shaffer JR, Marazita M, Foxman B. Bacterial community modifies host genetics effect on early childhood caries. In review.

17. Ware EB, Higgins C, Harris S, Fisher JD, Bakulski KM. Additive interaction and mediation-interaction decomposition: DNA methylation age acceleration, education, and cognitive impairment in the Health and Retirement Study. In review.

18. Reiner A, Bakulski KM, Fisher JD, Dou JF, Schneper L, Mitchell C, Notterman DA, Zawistowski M*, Ware EB*. Sex-specific DNA methylation in saliva from the multi-ethnic Fragile Families and Child Wellbeing Study. In review.

2023

1. Campbell KA, Hickman R, Fallin MD, Bakulski KM. Prenatal exposure to metals and autism spectrum disorder: Current status and future directions. Current Opinion in Toxicology. https://doi.org/10.1016/j.cotox.2021.04.001. In press

2. Elkin ER, Su AL, Dou JF, Colacino JA, Bridges D, Padmanabhan V, Harris SM, Boldenow E, Loch-Caruso R, Bakulski KM. 2023. Sexually-concordant and dimorphic transcriptional responses to maternal trichloroethylene and/or n-acetyl cysteine exposure in Wistar rat placental tissue. Toxicology. PMID: 36396003, PMCID: pending

2022

1. Blostein F, Bhaumik D, Davis E, Salzman E, Shedden K, Duhaime M, Bakulski KM, McNeal DW, Marazita ML, Foxman B. 2022. Evaluating the ecological hypothesis: Early life salivary microbiome assembly predicts dental caries in a longitudinal case-control study. Microbiome. PMID: 36567334; PubMed Central PMCID: PMC9791751

2. McCabe CF, Goodrich JM, Bakulski KM, Domino SE, Jones TR, Colacino JA, Dolinoy DC, Padmanabhan V. 2022. Probing prenatal bisphenol exposures and tissue-specific DNA methylation responses in cord blood, cord tissue, and placenta. Reproductive Toxicology. PMID: 36473650, PMCID: pending

3. Fernandez-Jimenez N, Fore R, Cilleros-Portet A, Lepeule J, Perron P, Kvist T, Tian F-Y, Lesseur C, Lozano M, Martorell-Marugán J, Loke J, Bakulski KM, Zhu Y, Forhan A, Sammallahti S, Everson TM, Chen J, Belmonte T, Carmona-Sáez P, Halliday J, Fallin MD, LaSalle J, Tost J, Czamara D, Fernández MF, Gómez-Martín A, Craig JM, Gonzalez-Alzaga B, Schmidt RJ, Dou JF, Muggli E, Lacasaña M, Vrijheid M, Marsit CJ, Karagas MR, Räikkönen K, Bouchard L, Heude B, Santa Marina L, Bustamante M, Hivert M-F, Ramon Bilbao J. 2022. A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health. Communications Biology. PMID: 36446949, PMCID: PMC9709064

4. Wang X, Bakulski KM, Mukherjee B, Hu H, Park SK. 2022. Cumulative lead exposure prediction model with the Super Learner algorithm. Chemosphere PMID: 36347347. PMCID: pending

5. Song AY, Bakulski KM, Feinberg JI, Newschaffer CJ, Croen LA, Hertz-Picciotto I, Schmidt RJ, Farzadagen H, Lyall K, Fallin MD, Volk HE, Ladd-Accosta C. 2022. Associations between accelerated parental biologic age, autism spectrum disorder, social traits, and developmental and cognitive outcomes in their children. Autism Research. PMID: 36189953, PMCID: PMC9722613 (Available December 1, 2023)

6. Elkin ER*, Higgins C*, Aung MT, Bakulski KM. 2022. Metals exposures and epigenetics: Current evidence and future directions. Current Environmental Health Reports. PMID: 36282474, PMCID: pending

7. Puttabyatappa M*, Saadat N*, Elangovan VR, Dou J, Bakulski KM, Padmanabhan V. 2022. Developmental programming: Impact of prenatal bisphenol-A exposure on liver and muscle transcriptome of female sheep. Toxicology and Applied Pharmacology. PMID: 35817127, PMCID: PMC9618258 (Available September 15, 2023)

Featured as cover art for the issue.

8. Blostein FA, Fisher J, Dou JSchenper L, Ware EB, Notterman DA, Mitchell C, Bakulski KM. 2022. Polymethylation scores for prenatal maternal smoke exposure persist until age 15 and are detected in saliva. Epigenetics. PMID: 35980258, PMCID: PMC9665138 (available August 18, 2023)

9. Dou JF, Middleton LYM, Zhu Y, Benke KS, Feinberg JI, Croen LA, Hertz-Picciotto I, Newschaffer CJ, LaSalle JM, Fallin MD*, Schmidt RJ*, Bakulski KM*. 2022. Prenatal vitamin intake in first month of pregnancy and DNA methylation in cord blood and placenta in two prospective cohorts. Epigenetics & Chromatin. PMID: 35918756, PMCID: PMC9344645

10. Harris S, Bakulski KM, Dou J, Houskamp E, Sheeres EC, Schellenboom E, Harlow O, Loch-Caruso R, Boldenow E. 2022. The trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine inhibits lipopolysaccharide-induced inflammation transcriptomic pathways and cytokine secretion in a macrophage cell model. Toxicology In Vitro. PMID: 35811015, PMCID: pending

11. Song AY, Feinberg JI, Bakulski KM, Croen LA, Fallin MD, Newschaffer CJ, Hertz-Picciotto I, Schmidt RJ, Ladd-Acosta C, Volk HE. 2022. Prenatal exposure to ambient air pollution and epigenetic aging at birth in newborns. Frontiers in Genetics. PMID: 35836579; PMCID: PMC9274082

12. Shu C, Jaffe AE, Sabunciyan S, Ji H, Astemborski J, Sun J, Bakulski KM, Sosnowski DW, Mehta SH, Kirk GD, Maher BS. 2022. Epigenome-wide association analyses of active injection drug use. Drug and Alcohol Dependence. PMID: 35395503, PMCID: pending

13. Elkin EK, Su AL, Kilburn B, Bakulski KM, Armant DR, Loch-Caruso R. 2022. Toxicity assessments of selected trichloroethylene and perchloroethylene metabolites in three in vitro human placental models. Reproductive Toxicology. PMID: 35304307, PMCID: PMC9107309 (available on April 1, 2023)

14. Solomon O, Huen K, Yousefi P, Küpers LK, González JR, Suderman M, Reese SE, Page CM, Gruzieva O, Rzehak P, Gao L, Bakulski KM, Novoloaca A, Allard C, Pappa I, Llambrich M, Vives M, Jima DD, Kvist T, Baccarelli A, White C, Rezwan FI, Sharp GC, Tindula G, Bergström A, Grote V, Dou JF, Isaevska E, Magnus MC, Corpeleijn E, Perron P, Jaddoe VWV, Nohr EA, Maitre L, Foraster M, Hoyo C, Håberg SE, Lahti J, DeMeo DL, Zhang H, Karmaus W, Kull I, Koletzko B, Feinberg JI, Gagliardi L, Bouchard L, Ramlau-Hansen CH, Tiemeier H, Santorelli G, Maguire RL, Czamara D, Litonjua A, Langhendries JP, Plusquin M, Lepeule J, Binder EB, Verduci E, Dwyer T, Carracedo A, Ferre N, Eskenazi B, Kogevinas M, Nawrot TS, Munthe-Kaas MC, Herceg Z, Relton C, Melén E, Gruszfeld D, Breton C, Fallin MD, Ghantous A, Nystad W, Heude B, Snieder H, Hivert MF, Felix JF, Sørensen TIA, Bustamante M, Murphy SK, Raikkönen K, Oken E, Holloway JW, Arshad SH, London SJ, Holland N. 2022. Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation. Mutation Research – Reviews in Mutation Research (MRR). PMID: 35690418, PMCID: PMC9623595 (available on March 14, 2023)

15. Zhu Y, Gomez JA, Laufer BI, Mordaunt CE, Mouat JS, Soto DC, Dennis MY, Benke KS, Bakulski KM, Dou J, Marathe R, Jianu JM, Williams LA, Gutierrez OJ, Walker CK, Ozonoff S, Feinberg JI, Fallin MD, Hertz-Picciotto I, Schmidt RJ, Yasui DH, LaSalle JM. 2022. Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism. Genome Biology. PMID: 35168652, PMCID: PMC8848662

16. Harris SM, Colacino JA, Buxton M, Croxton L, Nguyen V, Loch-Caruso R, Bakulski KM. 2022. A data mining approach reveals chemicals detected at higher levels in non-Hispanic Black women target preterm birth genes and pathways. Reproductive Sciences. PMID: 35107823, PMCID: PMC9288534 (available on July 1, 2023)

Selected as NIEHS extramural paper of the month for April 2022

Selected as NIEHS paper of the year for 2022 

2021

1. Brieger KK*, Phung MT*, Mukherjee B, Bakulski KM, Anton-Culver H, Bandera EV, Bowtell DDL, Cramer DW, deFazio A, Doherty JA, Fereday S, Fortner RT,  Gentry-Maharaj A, Goode EL, Goodman MT, Harris HR, Matsuo K, Menon U, Modugno F, Moysich K, Qin B, Ramus SJ, Risch H, Rossing MA, Schildkraut JM, Trabert B, Vierkant RA, Winham SJ, Wentzensen N, Wu AH, Ziogas A, Khoja L, Cho K, McLean K, Richardson J, Grout B, Chase A, McKinnon C, Odunsi K, Nelson BH, Brenton JD, Terry KL, Pharoah P, Berchuck A, Hanley GE, Webb PM, Pike MC, Pearce CL, for the Ovarian Cancer Association Consortium. 2021. High prediagnosis inflammation-related risk score associated with decreased ovarian cancer survival. Cancer Epidemiology Biomarkers & Prevention. PMID: 34789471, PMCID: PMC9281656

2. Bakulski KM, Dou JF, Feinberg JI, Aung MT, Ladd-Acosta C, Volk HE, Newschaffer CJ, Croen LA, Hertz-Picciotto, Levy SE, Landa R, Feinberg AP, Fallin MD. 2021. Autism-associated DNA methylation at birth from multiple tissues is enriched for autism genes in the Early Autism Risk Longitudinal Investigation (EARLI). Frontiers in Molecular Neuroscience. PMID: 34899183, PMCID: PMC8655859

3. Saadat N*, Puttabyatappa M*, Elangovan VR, Dou J, Thompson RC, Bakulski KM, Padmanabhan V*. 2021. Developmental Programming: Impact of Prenatal Testosterone Excess on Liver and Muscle Transcriptome and the Relationship Between Non-Coding and Coding RNA Networks in Female Sheep. Endocrinology. PMID: 34718504, PMCID: PMC8667859

4. Bakulski KM, Dou JF, Fisher J, Gard A, Schneper L, Notterman DA, Ware EB, Mitchell C. 2021. Particulate matter exposure in utero is associated with childhood saliva DNA methylation at ages 9 and 15: Applying cumulative DNA methylation scores as an exposure biomarker. Toxics. PMID: 34678958, PMCID: PMC8538839

5. Lozano M, Yousefi P, Broberg K, Soler-Blasco R, Miyashita C, Pesce G, Kim WJ, Rahman M, Bakulski KM, Haug LS, Ikeda-Araki A, Huel G, Park J, Relton C, Vrijheid M, Rifas-Shiman S, Oken E, Dou JF, Kishi R, Gutzkow KB, Annesi-Maesano I, Won S, Hivert MF, Fallin MD, Vafeiadi M, Ballester F, Bustamante M, Llop S. 2021. DNA methylation changes associated with prenatal mercury exposure: A meta-analysis of prospective cohort studies from PACE consortium. Environmental Research. PMID: 34562483, PMCID: pending.

6. Brieger KK, Bakulski KM, Pearce CL, Baylin A, Dou JF, Croen LA, Hertz-Picciotto I, Newschaffer CJ, Fallin MD, Schmidt RJ. 2021. The association of prenatal vitamins and folic acid supplement intake with risk for autism spectrum disorder in a high-risk sibling cohort, the Early Autism Risk Longitudinal Investigation (EARLI). Journal of Autism and Developmental Disabilities. PMID: 34110557, PMCID: pending, DOI: 10.1007/s10803-021-05110-9

7. Fu M, Bakulski KM, Higgins Tejera C, Ware EB. 2021. Mendelian randomization of dyslipidemia on cognitive impairment among older Americans. Frontiers in Neurology. PMID: 34248819, PMCID: PMC8260932

8. Rygiel C, Dolinoy DC, Bakulski KM, Aung MT, Perng W, Jones T, Solano-Gonzalez M, Hu H, Tellez-Rojo M, Schnaas L, Marcela E, Peterson K, Goodrich J. 2021. DNA methylation at birth mediates the association between prenatal lead (Pb) exposure and infant neurodevelopmental outcomes. Environmental Epigenetics. PMID: 34141453, PMCID: PMC8206046 

9. Middleton LYM, Dou JF, Fisher J, Heiss JA, Nguyen V, Just AC, Faul JD, Ware EB, Mitchell C, Colacino JA, Bakulski KM. 2021. Saliva cell type DNA methylation reference panel for epidemiology studies in children. Epigenetics. PMID: 33588693, PMCID: PMC8865319

10. Aung MT, Bakulski KM, Feinberg JI, Dou JF, Meeker JD, Mukherjee B, Loch-Caruso R, Ladd-Acosta C, Volk HE, Croen LA, Hertz-Picciotto I, Newschaffer CJ, Fallin MD. 2021. Maternal blood trace metal concentrations and whole blood DNA methylation during pregnancy in the Early Autism Risk Longitudinal Investigation (EARLI). Epigenetics. PMID: 33794742, PMCID: PMC8920182

11. Ware EB*, Morataya C*, Fu M, Bakulski KM. 2021. Type 2 diabetes and dementia in the Health and Retirement Study: A Mendelian randomization approach. Frontiers in Genetics. PMID: 33868373.  PMCID: PMC8044888

12. Elkin ER, Bakulski KM, Colacino JA, Bridges D, Kilburn BA, Armant DR, Ruden D, Loch-Caruso R. 2021. Transcriptional profiling of the response to the trichloroethylene metabolite S-(1,2- dichlorovinyl)-L-cysteine revealed activation of the eIF2α/ATF4 integrated stress response in two in vitro placental models. Archives in Toxicology. PMID: 33725128, PMCID: PMC7961173

13. Bakulski KM, Vadari HS, Faul JD, Heeringa SG, Kardia SLR, Langa KM, Smith JA, Manly JJ, Mitchell CM, Benke KS, Ware EB. 2021. Cumulative genetic risk and APOE-ε4 are independently associated with dementia status in a multi-ethnic, population-based cohort. Neurology Genetics. PMID: 33688582, PMCID: PMC7938646

2020

1. Dou JF, Puttabyatappa M, Padmanabhan V*, Bakulski KM*. 2020. Developmental Programming: Adipose Depot-Specific Transcriptional Regulation by Prenatal Testosterone Excess in a Sheep Model of PCOS. Molecular Cellular Endocrinology. PMID: 33359827, PMCID: PMC7854529

2. Bakulski KM, Dou JF, Feinberg JI, Brieger KK, Croen LA, Hertz-Picciotto I, Newschaffer CJ, Schmidt RJ, Fallin MD. 2020. Prenatal multivitamin use and MTHFR genotype are associated with newborn cord blood DNA methylation. International Journal of Environmental Research and Public Health. PMID: 33317014. PMCID: PMC7764679

3. McCabe CE, Padmanabhan V, Dolinoy DC, Domino SE, Jones T, Bakulski KM, Goodrich J. 2020. Maternal environmental exposure to bisphenols and epigenome-wide DNA methylation in infant cord blood. Environmental Epigenetics. PMID: 33391824. PMCID: PMC7757124

4. Ware EB, Mitchell CM, Faul JD, Bakulski KM. 2020. Considering the APOE locus in polygenic scores for Alzheimer’s disease in the Health and Retirement Study: A longitudinal panel study. BMC Medical Genomics. PMID: 33143703. PMCID: PMC7607711

5. Mordaunt CE, Jianu JM, Laufer B, Zhu Y, Dunaway KW, Bakulski KM, Feinberg JI, Volk HE, Lyall K, Croen LA, Newschaffer CJ, Ozonoff S, Hertz-Picciotto I, Fallin MD, Schmidt RJ, LaSalle JM. 2020. Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes. Genome Medicine. PMID: 33054850. PMCID: PMC7559201

6. Shu C, Jaffe AE, Sabunciyan S, Ji H, Astemborski J, Sun J, Bakulski KM, Mehta SH, Kirk GD, Maher BS. 2020. Epigenome-wide association scan identifies DNA methylation sites associated with HIV infection. Epigenomics. PMID: 33232214. PMCID: PMC7788472

7.  Davis E, Bakulski KM, Goodrich JM, Peterson KE, Marazita ML, Foxman B. 2020. Low levels of salivary metals, oral microbiome composition and dental decay. Scientific Reports. PMID: 32887894. PMCID: PMC7474081 

8. Campbell KA, Colacino JA, Park SK, Bakulski KM. 2020. Cell types in environmental epigenetic studies: Biological and epidemiological frameworks. Current Environmental Health Reports. PMID: 32794033. PMCID: PMC7493967

9. Brieger KK, Peterson S, Lee A, Mukherjee B, Bakulski KM, Anton-Culver H, Bandera EV, Berchuck A, Bowtell DDL, Chenevix-Trench G, Cho KR, Cramer DW, DeFazio A, Doherty JA, Fortner RT, Garsed DW, Gayther S, Gentry-Maharaj A, Goode EL, Goodman MT, Harris HR, Høgdall E, Jensen A, Johnatty SE, Jordan SJ, Kjaer SK, Kupryjanczyk J, Lambrechts D, McLean K, Menon U, Modugno F, Moysich K, Ness R, Ramus SJ, Richardson J, Risch H, Rossing MA, Trabert B, Wentzensen N, Ziogas A, Terry KL, Wu AH, Hanley GE, Pharoah P, Webb PM, Pike M, Pearce CL. 2020. Menopausal hormone therapy prior to the diagnosis of ovarian cancer is associated with improved survival. Gynecologic Oncology. PMID: 32641237. PMCID: PMC7487048 

10. Bakulski K M, Dou JF, Thompson RT, Lee C, Middleton LY, Bambarendage PUP, Ferris SP, Jones TR, Neier K, Zhou X, Sartor MA, Hammoud SS, Dolinoy DC, Colacino JA. 2020. Single cell analysis of the effects of developmental lead (Pb) exposure on the mouse hippocampus. Toxicological Sciences. PMID: 32458983. PMCID: PMC7416319

11. Puttabyatappa M*, Guo X*, Dou J, Dumesic D, Bakulski KM, Padmanabhan V. 2020. Developmental Programming: Granulosa and Theca Cell-Specific Transcriptional Regulation by Prenatal Testosterone in Sheep. Endocrinology. PMID: 32516392. PMCID: PMC7417881

12. Dou JF, Puttabyatappa M, Padmanabhan V*, Bakulski KM*. 2020. Developmental programming: Transcriptional regulation of visceral and subcutaneous adipose by prenatal bisphenol-A in female sheep. Chemosphere. PMID: 32417515. PMCID: PMC7418632

13. Bakulski KM, Seo YA, Hickman RC, Brandt D, Vadari HS, Hu H, Park SK. 2020. Heavy metals exposure and Alzheimer’s disease and related dementias. Journal of Alzheimer’s Disease. PMID: 32651318, PMCID: PMC7454042

14. Harris SM, Jin Y, Loch-Caruso R, Padilla IY, Meeker JD, Bakulski KM. 2020. Identification of environmental chemicals targeting miscarriage genes and pathways using the comparative toxicogenomics database. Environmental Research. PMID: 32143025, PMCID: PMC7103533

2019

1. Aung MT, Meeker JD, Boss J, Bakulski KM, Mukherjee B, Cantonwine D, McElrath T, Ferguson KK. 2019. Manganese is associated with increased plasma interleukin-1β during pregnancy, within a mixtures analysis framework of urinary trace metals. Reproductive Toxicology. PMID: 31881266, PMCID: PMC7138746

2. Jiang Y, Zhang H, Andrews S, Arshad H, Ewart S, Holloway JW, Fallin MD, Bakulski KM, Karmaus W. 2019. Estimation of Eosinophil Cells in Cord Blood with Adult Blood References via Bayesian Measurement Error Modeling. Bioinformatics. PMID: 31710672. doi: 10.1093/bioinformatics/btz839 

3. Mordaunt CE, Park BY, Bakulski KM, Feinberg JI, Croen LA, Ladd-Acosta C, Newschaffer CJ, Volk HE, Ozonoff S, Hertz-Picciotto I, LaSalle JM, Schmidt RJ, Fallin MD. 2019. A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in umbilical cord blood. Molecular Autism. PMID: 31673306, PMCID: PMC6814108 

4. Gervin K, Salas LA, Bakulski KM, Koestler DC, Wiencke JK, Kelsey KT, Kobor MS, Lyle R, Christensen BC, Felix J, Jones MJ. 2019. Systematic evaluation and validation of references and library selection methods for deconvolution of cord blood DNA methylation data. Clinical Epigenetics. PMID: 31455416, PMCID: PMC6712867 

5. Sikdar S, Joehanes R, Joubert BR, Xu C-J, Vives-Usano M, Rezwan FI, Felix JF, Ward JM, Guan W, Richmond RC, Brody JA, Küpers LK, Baïz N, Håberg SE, Smith JA, Reese SE, Aslibekyan S, Hoyo C, Dhingra R, Markunas C, Xu T, Reynolds LM, Just AC, Mandaviya PR, Ghantous A, Bennett BD, Wang T, Bakulski KM, Melen E, Zhao S, Jin J, Herceg Z, van Meurs J, Taylor JA, Baccarelli AA, Murphy SK, Liu Y, Munthe-Kaas MC, Deary IJ, Nystad W, Waldenberger M, Annesi-Maesano I, Conneely K, Jaddoe VWV, Arnett D, Snieder H, Kardia SLR, Relton CL, Ong KK, Ewart S, Moreno-Macias H, Romieu I, Sotoodehnia N, Fornage M, Koppelman GH, Bustamante M, Levy D, London SJ. 2019. Comparison of smoking related DNA methylation in newborns from maternal smoking in pregnancy, and in adults from personal smoking. Epigenomics. PMID: 31536415, PMCID: PMC6836223

6. Agha G, Mendelson MM, Ward-Caviness CK, Joehanes R, Huan TX, Gondalia R, Salfati E, Brody JA, Fiorito G, Bressler J, Chen BH, Ligthart S, Guarrera S, Colicino E, Just AC, Wahl S, Gieger C, Vandiver AV, Tanaka T, Hernandez DG, Pilling LC, Singleton AB, Sacerdote C, Krogh V, Panico S, Tumino R, Li Y, Zhang G, Stewart JD, Floyd JD, Wiggins KL, Rotter JI, Multhaup MM, Bakulski KM, Vokonas P, Hirschhorn J , Fallin MD, Liu C, Bandinelli S, Boerwinkle E, Dehghan A, Schwartz JD, Psaty BD, Feinberg AP, Hou L, Ferrucci L, Sotoodehnia N, Matullo G, Peters A, Fornage M, Assimes TL, Whitsel EA, Levy D, Baccarelli AA. 2019. Blood leukocyte DNA methylation predicts future risk of myocardial infarction and coronary heart disease: A study of 11,461 participants in nine population-based cohorts. Circulation. PMID: 31424985, PMCID: PMC6812683

7. Gruzieva O, Xu C-J, Yousefi P, Merid SK, Breton CV, Gao L, Volk HE, Feinberg JI, Ladd-Acosta C, Bakulski KM, Auffray C, Lemonnier N, Plusquin M, Herceg Z, Nawrot TS, Pizzi C, Richiardi L, Rusconi F, Ghantous A, Vineis P, Kogevinas M, Felix JF, Duijts L, den Dekker HT, Jaddoe VWV, Kluizenaar Y, Ruiz JL, Bustamante M, Antó JM, Sunyer J, Vrijheid M, Gutzkow KB, Grazuleviciene R, Hernandez-Ferrer C, Slama R, Bousquet J, Bergström A, Inger Kull I, Söderhäll C, Kere J, Just AC, Peng C, Pershagen G, Koppelman GH, London SJ, Baccarelli AA, Erik Melén E. 2019. Prenatal particulate air pollution and DNA methylation in newborns: An epigenome-wide meta-analysis. Environmental Health Perspectives. PMID: 31148503, PMCID: PMC6792178 

8. Dou JF, Farooqui Z, Faulk CD, Barks AK, Jones T, Dolinoy DC, Bakulski KM. 2019. Perinatal lead (Pb) exposure and cortical neuron-specific DNA methylation in male mice. Genes. PMID: 30987383, PMCID: PMC6523909

9. Bakulski KM, Dou J, Lin N, London SJ, Colacino JA. 2019. DNA methylation signature of smoking in lung cancer is enriched for exposure signatures in newborn and adult blood. Scientific Reports. PMID: 30872662, PMCID: PMC6418160

Top 10% of cancer papers downloaded from Scientific Reports in 2019

10. Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, Breton CV, Allard C, Just AC, Bakulski KM, Holloway JW, Everson TM, Xu C-J, Huang R-C, van der Plaat DA, Wielscher M, Merid SK, Ullemar V, Rezwan FI, Lahti J, van Dongen J, Langie SAB, Richardson TG, Magnus MC, Nohr EA, Xu Z, Duijts L, Zhao S, Zhang W, Plusquin M, DeMeo DL, Solomon O, Heimovaara JH, Jima DD, Gao L, Bustamante M, Perron P, Wright RO, Hertz-Picciotto I, Zhang H, Karagas MR, Gehring U, Marsit CJ, Beilin LJ, Vonk JM, Jarvelin M-R, Bergström A, Örtqvist AK, Ewart S, Villa PM, Moore SE, Willemsen G, Standaert ARL, Håberg SE, Sørensen TIA, Taylor JA, Räikkönen K, Yang IV, Kechris K, Nawrot TS, Silver MJ, Richiardi L, Kogevinas M, Litonjua A, Eskenzi B, Mbarek H, Maguire RL, Dwyer T, Vrijheid M, Bouchard L, Baccarelli A, Croen LA, Karmaus W, Anderson D, de Vries M, Sebert S, Kere J, Karlsson R, Arshad SH, Hämäläinen E, Routledge MN, Boomsma DI, Feinberg AP, Newschaffer CJ, Govarts E, Moisse M, Fallin MD, Melén E, Prentice AM, Kajantie E, Almqvist C, Oken E, Dabelea D, Boezen HM, Melton PE, Wright RJ, Koppelman GH, Trevisi L, Hivert M-F , Sunyer J, Munthe-Kaas MC, Murphy SK, Corpeleijn E, Wiemels J, Holland N, Herceg Z, Binder E, Davey Smith G, Jaddoe VW, Lie RT, Nystad W, London SJ, Lawlor DL, Relton CL, Snieder H, Felix JF. 2019. A meta-analysis of epigenome-wide association studies in neonates reveals widespread differential methylation associated with birthweight. Nature Communications. PMID: 31015461, PMCID: PMC6478731 

2018

1. Aung MT, Ferguson KK, Cantonwine DE, Bakulski KM, Mukherjee BM, Loch-Caruso R, McElrath T, Meeker JD. 2018.  Longitudinal associations between maternal plasma measurements of inflammatory markers and urinary levels of phenols and parabens during pregnancy. Science of the Total Environment. PMID: 30308801. PMCID: PMC6236678

2. Wang W, Moroi S, Bakulski KM, Mukherjee B, Weisskopf MG, David Sparrow D, Vokonas PS, Hu H, Park SK. 2018. Cumulative Lead Exposure and Risk of Incident Primary Open-Angle Glaucoma: the VA Normative Aging Study. Environmental Health Perspectives. PMID: 30102601. PMCID: PMC6108844

Selected as NIEHS October 2018 extramural paper of the month

3. Dou J, Schmidt RJ, Benke KS, Newschaffer CJ, Hertz-Picciotto I, Croen LA, Iosif AM, LaSalle JM, Fallin MD, Bakulski KM. 2018. Cord blood buffy coat DNA methylation is comparable to whole cord blood DNA methylation measures. Epigenetics. PMID: 29451060. PMCID: PMC5836975

2017

1. Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, Burchard EG, Bustamante M, Chatzi L, Cheng Munthe-Kaas M, Corpeleijn E, Czamara D, Dabelea D, Davey Smith G, De Boever P, Duijts L, Dwyer T, Eng C, Eskenazi B, Everson TM, Falahi F, Fallin MD, Farchi S, Fernandez MF, Gao L, Gaunt TR, Ghantous A, Gillman MW, Gonseth S, Grote V, Gruzieva O, Håberg SE, Herceg Z, Hivert MF, Holland N, Holloway JW, Hoyo C, Hu D, Huang RC, Huen K, Järvelin MR, Jima DD, Just AC, Karagas MR, Karlsson R, Karmaus W, Kechris KJ, Kere J, Kogevinas M, Koletzko B, Koppelman GH, Küpers LK, Ladd-Acosta C, Lahti J, Lambrechts N, Langie SAS, Lie RT, Liu AH, Magnus MC, Magnus P, Maguire RL, Marsit CJ, McArdle W, Melén E, Melton P, Murphy SK, Nawrot TS, Nisticò L, Nohr EA, Nordlund B, Nystad W, Oh SS, Oken E, Page CM, Perron P, Pershagen G, Pizzi C, Plusquin M, Raikkonen K, Reese SE, Reischl E, Richiardi L, Ring S, Roy RP, Rzehak P, Schoeters G, Schwartz DA, Sebert S, Snieder H, Sørensen TIA, Starling AP, Sunyer J, Taylor JA, Tiemeier H, Ullemar V, Vafeiadi M, Van Ijzendoorn MH, Vonk JM, Vriens A, Vrijheid M, Wang P, Wiemels JL, Wilcox AJ, Wright RJ, Xu CJ, Xu Z, Yang IV, Yousefi P, Zhang H, Zhang W, Zhao S, Agha G, Relton CL, Jaddoe VWV, London SJ. 2017. Cohort profile: Pregnancy and childhood epigenetics (PACE) consortium. International Journal of Epidemiology. PMID: 29025028. PMCID: PMC5837319

2. Sharp GC, Salas LA, Monnereau C, Allard C, Yousefi P, Everson TM, Bohlin J, Xu Z, Huang RC, Reese SE, Xu CJ, Baïz N, Hoyo C, Agha G, Roy R, Holloway JW, Ghantous A, Merid SK, Bakulski KM, Küpers LK, Zhang H, Richmond RC, Page CM, Duijts L, Lie RT, Melton PE, Vonk JM, Nohr EA, Williams-DeVane C, Huen K, Rifas-Shiman SL, Ruiz-Arenas C, Gonseth S, Rezwan FI, Herceg Z, Ekström S, Croen L, Falahi F, Perron P, Karagas MR, Quraishi BM, Suderman M, Magnus MC, Jaddoe VWV, Taylor JA, Anderson D, Zhao S, Smit HA, Josey MJ, Bradman A, Baccarelli AA, Bustamante M, Håberg SE, Pershagen G, Hertz-Picciotto I, Newschaffer C, Corpeleijn E, Bouchard L, Lawlor DA, Maguire RL, Barcellos LF, Davey Smith G, Eskenazi B, Karmaus W, Marsit CJ, Hivert MF, Snieder H, Fallin MD, Melén E, Munthe-Kaas MC, Arshad H, Wiemels JL, Annesi-Maesano I, Vrijheid M, Oken E, Holland N, Murphy SK, Sørensen TIA, Koppelman GH, Newnham JP, Wilcox AJ, Nystad W, London SJ, Felix JF, Relton CL. 2017. Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: Findings from the Pregnancy and Childhood Epigenetics (PACE) consortium. Human Molecular Genetics. PMID: 29016858. PMCID: PMC5656174

3. Andrews SV, Ellis SE, Bakulski KM, Sheppard B, Croen LA, Hertz-Picciotto I, Newschaffer CJ, Feinberg AP, Arking DE, Ladd-Acosta C, Fallin MD. 2017. Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder. Nature Communications. PMID: 29066808. PMCID: PMC5654961

4. Peng Q, Bakulski KM, Nan B, Park SK. 2017. Urinary and Blood Cadmium and Alzheimer’s Disease Mortality in U.S. Adults. Environmental Research. PMID: 28511080. PMCID: PMC5513740

2016

1. Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhn MA, Agha G, Bressler J, Ward-Caviness CK, Chen BH, Huan T, Bakulski KM, Salfati EL, WHI-EMPC Investigators, Fiorito G, CHARGE epigenetics of conronary heart disease, Wahl S, Schramm K, Sha J, Hernandez DG, Just AC, Smith JA, Sotoodehnia N, Pilling LC, Pankow JS, Tsao P, Liu C, Zhao W, Guarrea S, Micholoulos J, Smith AK, Peters MJ, Melzer D, Vokonas P, Fornage M, Prokisch J, Bis JC, Chu AY, Herder C, Grallert H, Yao C, Shah S, McRae AF, Lin H, Horvath S, Fallin MD, Hofman A, Wareham NJ, Wiggins KL, Feinberg AP, Sarr JM, Visscher PM, Murabito JM, Kardia SLR, Absher DM, Binder EB, Singleton AB, Bandinelli S, Peters A, Waldenberger M, Matullo G, Schwartz JD, Demerath EW, Uitterlinden AG, van Muers JBJ, Franco OH, Chen YDI, Levy D, Turner ST, Deary IJ, Ressler KJ, Dupuis J, Ferrucci L, Ong KK, Assimes TL, Boerwinckle EA, Koenig W, Arnett DK, Baccarelli A, Benjamin EJ, Dehghan A. 2016. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology. PMID: 27955697. PMCID: PMC5151130

2. Bakulski KM, Halladay A, Hu VW, Mill J, Fallin MD. 2016. Epigenetic research in neuropsychiatric disorders: The “tissue issue”. Current Behavioral Neuroscience Reports. PMID: 28093577. PMCID: PMC5235359

3. Farooqui Z, Bakulski KM, Power MC, Weisskopf MG, Sparrow D, Spiro A, Vokonas PS, Nie LH, Park SK. 2016. The association of Pb exposure and longitudinal changes in Mini-Mental Status Exam scores, global cognition and domains of cognition over time: The VA Normative Aging Study. Environmental Research. PMID: 27770710. PMCID: PMC5135609

4. Cardenas A, Allard C, Doyon M, Houseman EA, Bakulski KM, Perron P, Bouchard L, Hivert M-F. 2016. Validation of a DNA methylation reference panel for the estimation of nucleated cell types in cord blood. Epigenetics. PMID: 27668573. PMCID: PMC5221601

5. Joubert BR*, Felix JF*, Yosefi P*, Bakulski KM*, Just AC*, Breton C*, Reese S*, Markunas C*, Richmond RC*, Xu C-J*, Kupers L*, Oh S*, Hoyo C*, Gruzieva O, Soderhall C, Salas LA, Baiz N, Zhang H, Lepeule J, Ruiz C, Ligthart S, Wang T, Taylor J, Duijts L, Sharp GC, Jankipersadsing SA, Nilson RM, Vaez A, Fallin MD, Hu D, Litonjua AA, Fuemmeler BF, Huen K, Kere J, Kull I, Munthe-Kaas MC, Gehring U, Gonzalez JR, Peters MJ, Maberg SE, Xu Z, van Muers JB, Gaunt TR, Kerkhof M, Crpelejin E, Feinberg AP, Eng C, Baccarelli AA, Benjamin Neelon SE, Bradman A, Merid SK, Bergstrom A, Herceg Z, Yao J, Lemonnier N, Franco OH, Wu MC, Hofman A, McArdle W, Van der Vlies P, Falahi F, Gillman MW, Barcellos LF, Kumar A, Wickman M, Guerra S, Charles MA, Holloway J, Auffray C, Tiemeier HW, Davey Smith G, Postma D, Hivert MF, Eskenazi B, Vrijheid M, Arshad H, Anto JM, Dehghan A, Karmaus W, Annesi-Maesano I, Sunyer J, Ghantous A, Pershagen G, Holland N, Murphy S, DeMeo DL, Burchard EG, Ladd-Acosta C, Snieder H, Nystad W, Koppelman GH, Relton CL, Jaddoe VWV, Wolcox A, Melen E, London SJ. 2016. DNA methylation in newborns and maternal smoking in pregnancy: Genome-wide consortium meta-analysis. American Journal of Human Genetics. PMID: 27040690. PMCID: PMC4833289

6. Bakulski KM, Feinberg JI, Andrews S, Yang J, McKenney S, Witter F, Brown S, Walston J, Feinberg AP, Fallin MD. 2016. DNA methylation of cord blood cell types: Applications for mixed cell birth studies. Epigenetics. PMID: 27019159. PMCID: PMC4889293

2015

1. Feinberg JI, Bakulski KM, Jaffe AE, Trygvadottier R, Brown S, Goldman LR, Croen LA, Hertz-Picciotto I, Newschaffer CJ, Fallin MD, Feinberg AP. 2015. ­­­Paternal sperm DNA methylation associated with early signs of autism risk in an autism-enriched cohort. International Journal of Epidemiology. PMID: 25878217. PMCID: PMC4598797

2. Bakulski KM*, Lee HJ*, Feinberg JI, Wells EM, Brown S, Herbstman J, Witter FR, Halden RU, Caldwell K, Mortensen ME, Jaffe AE, Moye Jr. J, Caulfield LE, Pan Y, Tollerud DJ, Goldman LR**, Feinberg AP**, Fallin MD**.  2015. Prenatal mercury concentration is associated with changes in DNA methylation at TCEANC2 in newborns. International Journal of Epidemiology. PMID: 25906783. PMCID: PMC4588863

2014

1. Bakulski KM, Park SK, Weisskopf MG, Tucker KL, Sparrow D, Spiro A, Vokanas PS, Nie LH, Hu H, Weuve J. 2014. Lead exposure, B-vitamins, and plasma homocysteine in older men. Environmental Health Perspectives. PMID: 24905780. PMCID: PMC4181916

2. Bakulski KM, Fallin MD. 2014. Epigenetic epidemiology: Promises for public health research. Environmental & Molecular Mutagenesis. PMID: 24449392. PMCID: PMC4011487

2012

1. Bakulski KM, Dolinoy DC, Sartor MA, Paulson HL, Lieberman AP, Konen JR, Albin RL, Hu H, Rozek LS. 2012. Genome-wide DNA methylation differences between late-onset Alzheimer’s disease and cognitively normal controls in human frontal cortex. Journal of Alzheimer’s Disease. PMID: 22451312. PMCID: PMC3652332

2. Bakulski KM, Dolinoy DC, Paulson HL, Rozek LS, Hu H. 2012. Alzheimer’s disease and environmental exposure to lead: The epidemiologic evidence and potential role of epigenetics. Current Alzheimer Research. PMID: 22272628. PMCID: PMC3567843