Publications

Martin-Gonzalez E, Perez-Garcia J, Martin-Almeida M, Hernández-Pérez JM, González-Pérez R, Sardón O, Pérez-Pérez JA, González-Carracedo MA, Poza-Guedes P, Sánchez-Machín I, Mederos-Luis E, Corcuera P, López-Fernández L, Román-Bernal B, González-García LM, Cruz MJ, González-Barcala FJ, Martínez-Rivera C, Mullol J, Muñoz X, Olaguibel JM, Plaza V, Quirce S, Valero A, Sastre J, Del Pozo V, Villar J, Lorenzo-Diaz F, Pino-Yanes M. Genome-wide Association Study of Asthma Exacerbations in the Spanish Population. Arch Bronconeumol. 2025 Mar 20:S0300-2896(25)00091-2. English, Spanish. doi: 10.1016/j.arbres.2025.03.012. Epub ahead of print. PMID: 40187921.

Martin-Gonzalez E, Perez-Garcia J, Herrera-Luis E, Martin-Almeida M, Kebede-Merid S, Hernandez-Pacheco N, Lorenzo-Diaz F, González-Pérez R, Sardón O, Hernández-Pérez JM, Poza-Guedes P, Sánchez-Machín I, Mederos-Luis E, Corcuera P, López-Fernández L, Román-Bernal B, Toncheva AA, Harner S, Wolff C, Brandstetter S, Abdel-Aziz MI, Hashimoto S, Vijverberg SJH, Kraneveld AD, Potočnik U, Kabesch M, Maitland-van der Zee AH, Villar J, Melén E, Pino-Yanes M. Epigenome-Wide Association Study of Asthma Exacerbations in Europeans. Allergy. 2025 Feb 5. doi: 10.1111/all.16490. Epub ahead of print. PMID: 39907155.

Martín-González E, Hernández-Pérez JM, Pérez Pérez JA, Pérez-García J, Herrera-Luis E, González-Pérez R, González-González O, Mederos-Luis E, Sánchez-Machín I, Poza-Guedes P, Sardón O, Corcuera P, Cruz MJ, González-Barcala FJ, Martínez-Rivera C, Mullol J, Muñoz X, Olaguibel JM, Plaza V, Quirce S, Valero A, Sastre J, Korta-Murua J, Del Pozo V, Lorenzo-Díaz F, Villar J, Pino-Yanes M, González-Carracedo MA. Alpha-1 antitrypsin deficiency and Pi*S and Pi*Z SERPINA1 variants are associated with asthma exacerbations. Pulmonology. 2025 Dec 31;31(1):2416870. doi: 10.1016/j.pulmoe.2023.05.002. Epub 2024 Oct 25.

Perez-Garcia J, Cardenas A, Lorenzo-Diaz F, Pino-Yanes M. Precision medicine for asthma treatment: Unlocking the potential of the epigenome and microbiome. J Allergy Clin Immunol. 2025 Feb;155(2):298-315. doi: 10.1016/j.jaci.2024.06.010. Epub 2024 Jun 19. PMID: 38906272.

Alizadeh Bahmani AH, Abdel-Aziz MI, Hashimoto S, Bang C, Brandstetter S, Corcuera-Elosegui P, Franke A, Gorenjak M, Harner S, Kheiroddin P, López-Fernández L, Neerincx AH, Pino-Yanes M, Potočnik U, Sardón-Prado O, Toncheva AA, Wolff C, Kabesch M, Kraneveld AD, Vijverberg SJH, Maitland-van der Zee AH, On Behalf Of The SysPharmPediA Consortium. Association of Corticosteroid Inhaler Type with Saliva Microbiome in Moderate-to-Severe Pediatric Asthma. Biomedicines. 2025 Jan 2;13(1):89. doi: 10.3390/biomedicines13010089. PMID: 39857673. 

Alizadeh Bahmani AH, Vijverberg SJH, Hashimoto S, Wolff C, Almqvist C, Bloemsma LD, Brandstetter S, Corcuera-Elosegui P, Gorenjak M, Harner S, Hedman AM, Kabesch M, López-Fernández L, Kraneveld AD, Neerincx AH, Pino-Yanes M, Potočnik U, Sardón-Prado O, Dierdorp BS, Dekker T, Metwally NKA, Duitman JW, Lutter R, Brinkman P, Abdel-Aziz MI, Maitland-van der Zee AH. Association of blood inflammatory phenotypes and asthma burden in children with moderate-to-severe asthma. ERJ Open Res. 2024 Dec 16;10(6):00222-2024. doi: 10.1183/23120541.00222-2024. eCollection 2024 Nov. PMID: 39687398.

Herrera-Luis E, Martin-Almeida M, Pino-Yanes M. Asthma-Genomic Advances Toward Risk Prediction. Clin Chest Med. 2024 Sep;45(3):599-610. doi: 10.1016/j.ccm.2024.03.002. Epub 2024 Apr 21. PMID: 39069324.

Puga M, Serrano JG, García EL, González Carracedo MA, Jiménez-Canino R, Pino-Yanes M, Karlsson R, Sullivan PF, Fregel R. El Hierro Genome Study: A Genomic and Health Study in an Isolated Canary Island Population. J Pers Med. 2024 Jun 12;14(6):626. doi: 10.3390/jpm14060626. PMID: 38929847.

Shahbazi Khamas S, Van Dijk Y, Abdel-Aziz MI, Neerincx AH, Maarten Blankestijn J, Vijverberg SJH, Hashimoto S, Bush A, Kraneveld AD, Hedman AM, Toncheva AA, Almqvist C, Wolff C, Murray CS, Hedlin G, Roberts G, Adcock IM, Korta-Murua J, Bønnelykke K, Fleming LJ, Pino-Yanes M, Gorenjak M, Kabesch M, Sardón-Prado O, Montuschi P, Singer F, Elosegui PC, Fowler SJ, Brandstetter S, Harner S, Dahlén SE, Potočnik U, Frey U, van Aalderen W, Brinkman P, Maitland-van der Zee AH; SysPharmPediA and U-BIOPRED Consortia. Exhaled Volatile Organic Compounds for Asthma Control Classification in Children with Moderate to Severe Asthma: Results from the SysPharmPediA Study. Am J Respir Crit Care Med. 2024 Nov 1;210(9):1091-1100. doi: 10.1164/rccm.202312-2270OC. PMID: 38648186.

Herrera-Luis E, Rosa-Baez C, Huntsman S, Eng C, Beckman KB, LeNoir MA, Rodriguez-Santana JR, Villar J, Laprise C, Borrell LN, Ziv E, Burchard EG, Pino-Yanes M. Novel insights into the whole-blood DNA methylome of asthma in ethnically diverse children and youth. Eur Respir J. 2023 Dec 21;62(6):2300714. doi: 10.1183/13993003.00714-2023. PMID: 37802634; PMCID: PMC10841414.

Budu-Aggrey A, Kilanowski A, Sobczyk MK; 23andMe Research Team; Shringarpure SS, Mitchell R, Reis K, Reigo A; Estonian Biobank Research Team; Mägi R, Nelis M, Tanaka N, Brumpton BM, Thomas LF, Sole-Navais P, Flatley C, Espuela-Ortiz A, Herrera-Luis E, Lominchar JVT, Bork-Jensen J, Marenholz I, Arnau-Soler A, Jeong A, Fawcett KA, Baurecht H, Rodriguez E, Alves AC, Kumar A, Sleiman PM, Chang X, Medina-Gomez C, Hu C, Xu CJ, Qi C, El-Heis S, Titcombe P, Antoun E, Fadista J, Wang CA, Thiering E, Wu B, Kress S, Kothalawala DM, Kadalayil L, Duan J, Zhang H, Hadebe S, Hoffmann T, Jorgenson E, Choquet H, Risch N, Njølstad P, Andreassen OA, Johansson S, Almqvist C, Gong T, Ullemar V, Karlsson R, Magnusson PKE, Szwajda A, Burchard EG, Thyssen JP, Hansen T, Kårhus LL, Dantoft TM, Jeanrenaud ACSN, Ghauri A, Arnold A, Homuth G, Lau S, Nöthen MM, Hübner N, Imboden M, Visconti A, Falchi M, Bataille V, Hysi P, Ballardini N, Boomsma DI, Hottenga JJ, Müller-Nurasyid M, Ahluwalia TS, Stokholm J, Chawes B, Schoos AM, Esplugues A, Bustamante M, Raby B, Arshad S, German C, Esko T, Milani LA, Metspalu A, Terao C, Abuabara K, Løset M, Hveem K, Jacobsson B, Pino-Yanes M, Strachan DP, Grarup N, Linneberg A, Lee YA, Probst-Hensch N, Weidinger S, Jarvelin MR, Melén E, Hakonarson H, Irvine AD, Jarvis D, Nijsten T, Duijts L, Vonk JM, Koppelmann GH, Godfrey KM, Barton SJ, Feenstra B, Pennell CE, Sly PD, Holt PG, Williams LK, Bisgaard H, Bønnelykke K, Curtin J, Simpson A, Murray C, Schikowski T, Bunyavanich S, Weiss ST, Holloway JW, Min JL, Brown SJ, Standl M, Paternoster L. European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation. Nat Commun. 2023 Oct 4;14(1):6172. doi: 10.1038/s41467-023-41180-2. PMID: 37794016; PMCID: PMC10550990.

Perez-Garcia J, Pino-Yanes M, Plender EG, Everman JL, Eng C, Jackson ND, Moore CM, Beckman KB, Medina V, Sharma S, Winnica DE, Holguin F, Rodríguez-Santana J, Villar J, Ziv E, Seibold MA, Burchard EG. Epigenomic response to albuterol treatment in asthma-relevant airway epithelial cells. Clin Epigenetics. 2023 Oct 3;15(1):156. doi: 10.1186/s13148-023-01571-0. PMID: 37784136; PMCID: PMC10546710.

Perez-Garcia J, Pino-Yanes M, Lorenzo-Diaz F. Reply. J Allergy Clin Immunol. 2023 Dec;152(6):1683-1685. doi: 10.1016/j.jaci.2023.08.023. Epub 2023 Sep 22. PMID: 37747396.

Espuela-Ortiz A, Martin-Gonzalez E, Poza-Guedes P, González-Pérez R, Herrera-Luis E. Genomics of Treatable Traits in Asthma. Genes (Basel). 2023 Sep 20;14(9):1824. doi: 10.3390/genes14091824. PMID: 37761964; PMCID: PMC10531302.

Serrano JG, Ordóñez AC, Santana J, Sánchez-Cañadillas E, Arnay M, Rodríguez-Rodríguez A, Morales J, Velasco-Vázquez J, Alberto-Barroso V, Delgado-Darias T, de Mercadal MCC, Hernández JC, Moreno-Benítez MA, Pais J, Ringbauer H, Sikora M, McColl H, Pino-Yanes M, Ferrer MH, Bustamante CD, Fregel R. The genomic history of the indigenous people of the Canary Islands. Nat Commun. 2023 Aug 15;14(1):4641. doi: 10.1038/s41467-023-40198-w. PMID: 37582830; PMCID: PMC10427657.

Perez-Garcia J, Espuela-Ortiz A, Hernández-Pérez JM, González-Pérez R, Poza-Guedes P, Martin-Gonzalez E, Eng C, Sardón-Prado O, Mederos-Luis E, Corcuera-Elosegui P, Sánchez-Machín I, Korta-Murua J, Villar J, Burchard EG, Lorenzo-Diaz F, Pino-Yanes M. Human genetics influences microbiome composition involved in asthma exacerbations despite inhaled corticosteroid treatment. J Allergy Clin Immunol. 2023 Sep;152(3):799-806.e6. doi: 10.1016/j.jaci.2023.05.021. Epub 2023 Jun 8. PMID: 37301411; PMCID: PMC10522330.

Martin-Almeida M, Perez-Garcia J, Herrera-Luis E, Rosa-Baez C, Gorenjak M, Neerincx AH, Sardón-Prado O, Toncheva AA, Harner S, Wolff C, Brandstetter S, Valletta E, Abdel-Aziz MI, Hashimoto S, Berce V, Corcuera-Elosegui P, Korta-Murua J, Buntrock-Döpke H, Vijverberg SJH, Verster JC, Kerssemakers N, Hedman AM, Almqvist C, Villar J, Kraneveld AD, Potočnik U, Kabesch M, Zee AHM, Pino-Yanes M, On Behalf Of The SysPharmPediA Consortium. Epigenome-Wide Association Studies of the Fractional Exhaled Nitric Oxide and Bronchodilator Drug Response in Moderate-to-Severe Pediatric Asthma. Biomedicines. 2023 Feb 23;11(3):676. doi: 10.3390/biomedicines11030676. PMID: 36979655; PMCID: PMC10044864.

Blankestijn JM, Lopez-Rincon A, Neerincx AH, Vijverberg SJH, Hashimoto S, Gorenjak M, Sardón Prado O, Corcuera-Elosegui P, Korta-Murua J, Pino-Yanes M, Potočnik U, Bang C, Franke A, Wolff C, Brandstetter S, Toncheva AA, Kheiroddin P, Harner S, Kabesch M, Kraneveld AD, Abdel-Aziz MI, Maitland-van der Zee AH; SysPharmPediA Consortium. Classifying asthma control using salivary and fecal bacterial microbiome in children with moderate-to-severe asthma. Pediatr Allergy Immunol. 2023 Feb;34(2):e13919. doi: 10.1111/pai.13919. PMID: 36825736.

Perez-Garcia J, Herrera-Luis E, Li A, Mak ACY, Huntsman S, Oh SS, Elhawary JR, Eng C, Beckman KB, Hu D, Lorenzo-Diaz F, Lenoir MA, Rodriguez-Santana J, Zaitlen N, Villar J, Borrell LN, Burchard EG, Pino-Yanes M. Multi-omic approach associates blood methylome with bronchodilator drug response in pediatric asthma. J Allergy Clin Immunol. 2023 Jun;151(6):1503-1512. doi: 10.1016/j.jaci.2023.01.026. Epub 2023 Feb 14. PMID: 36796456.

Alizadeh Bahmani AH, Slob EMA, Bloemsma LD, Brandstetter S, Corcuera-Elosegui P, Gorenjak M, Harner S, Hashimoto S, Hedman AM, Kabesch M, Koppelman GH, Korta-Murua J, Kraneveld AD, Neerincx AH, Pijnenburg MW, Pino-Yanes M, Potočnik U, Sardón-Prado O, Vijverberg SJH, Wolff C, Abdel-Aziz MI, Maitland-van der Zee AH; SysPharmPediA consortium. Medication use in uncontrolled pediatric asthma: Results from the SysPharmPediA study. Eur J Pharm Sci. 2023 Feb 1;181:106360. doi: 10.1016/j.ejps.2022.106360. Epub 2022 Dec 13. PMID: 36526249.

Herrera-Luis E, Forno E, Celedón JC, Pino-Yanes M. Asthma Exacerbations: The Genes Behind the Scenes. J Investig Allergol Clin Immunol. 2023 Apr 18;33(2):76-94. doi: 10.18176/jiaci.0878. Epub 2022 Nov 24. PMID: 36420738; PMCID: PMC10638677.

Perez-Garcia J, González-Carracedo M, Espuela-Ortiz A, Hernández-Pérez JM, González-Pérez R, Sardón-Prado O, Martin-Gonzalez E, Mederos-Luis E, Poza-Guedes P, Corcuera-Elosegui P, Callero A, Sánchez-Machín I, Korta-Murua J, Pérez-Pérez JA, Villar J, Pino-Yanes M, Lorenzo-Diaz F. The upper-airway microbiome as a biomarker of asthma exacerbations despite inhaled corticosteroid treatment. J Allergy Clin Immunol. 2023 Mar;151(3):706-715. doi: 10.1016/j.jaci.2022.09.041. PMID: 36343772.

Herrera-Luis E, Mak ACY, Perez-Garcia J, Martin-Gonzalez E, Eng C, Beckman KB, Huntsman S, Hu D, González-Pérez R, Hernández-Pérez JM, Mederos-Luis E, Sio YY, Poza-Guedes P, Sardón O, Corcuera P, Sánchez-Machín I, Korta-Murua J, Martínez-Rivera C, Mullol J, Muñoz X, Valero A, Sastre J, Garcia-Aymerich J, Llop S, Torrent M, Casas M, Rodríguez-Santana JR, Villar J, Del Pozo V, Lorenzo- Diaz F, Williams LK, Melén E, Chew FT, Borrell LN, Burchard EG, Pino-Yanes M. Admixture mapping of severe asthma exacerbations in Hispanic/Latino children and youth. Thorax. 2023 Mar;78(3):233-241. doi: 10.1136/thorax-2022-218755. doi: 10.1136/thorax-2022-218755. PMID: 36180068; PMCID: PMC9957797.

Slob EMA, Faiz A, van Nijnatten J, Vijverberg SJH, Longo C, Kutlu M, Chew FT, Sio YY, Herrera-Luis E, Espuela-Ortiz A, Perez-Garcia J, Pino-Yanes M, Burchard EG, Potočnik U, Gorenjak M, Palmer C, Maroteau C, Turner S, Verhamme K, Karimi L, Mukhopadhyay S, Timens W, Hiemstra PS, Pijnenburg MW, Neighbors M, Grimbaldeston MA, Tew GW, Brandsma CA, Berce V, Aliee H, Theis F, Sin DD, Li X, van den Berge M, Maitland-van der Zee AH, Koppelman GH. Association of bronchial steroid inducible methylation quantitative trait loci with asthma and chronic obstructive pulmonary disease treatment response. Clin Transl Allergy. 2022 Aug;12(8):e12173. doi: 10.1002/clt2.12173. PMID: 36036237; PMCID: PMC9421427.

Perez-Garcia J, Pino-Yanes M. Novel insights into the biological pathways involved in severe asthma. Respirology. 2022 Sep;27(9):680-681. doi: 10.1111/resp.14319. Epub 2022 Jun 28. PMID: 35764405.

Herrera-Luis E, Ortega VE, Ampleford EJ, Sio YY, Granell R, de Roos E, Terzikhan N, Vergara EE, Hernandez-Pacheco N, Perez-Garcia J, Martin-Gonzalez E, Lorenzo-Diaz F, Hashimoto S, Brinkman P; U-BIOPRED Study Group, Jorgensen AL, Yan Q, Forno E, Vijverberg SJ, Lethem R, Espuela-Ortiz A, Gorenjak M, Eng C, González-Pérez R, Hernández-Pérez JM, Poza-Guedes P, Sardón O, Corcuera P, Hawkins GA, Marsico A, Bahmer T, Rabe KF, Hansen G, Kopp MV, Rios R, Cruz MJ, González-Barcala FJ, Olaguibel JM, Plaza V, Quirce S, Canino G, Cloutier M, Del Pozo V, Rodriguez-Santana JR, Korta-Murua J, Villar J, Potočnik U, Figueiredo C, Kabesch M, Mukhopadhyay S, Pirmohamed M, Hawcutt DB, Melén E, Palmer CN, Turner S, Maitland-van der Zee AH, von Mutius E, Celedón JC, Brusselle G, Chew FT, Bleecker E, Meyers D, Burchard EG, Pino-Yanes M. Multi-ancestry genome-wide association study of asthma exacerbations. Pediatr Allergy Immunol. 2022 Jun;33(6):e13802. doi: 10.1111/pai.13802. PMID: 35754128; PMCID: PMC9671132.

Herrera-Luis E, Li A, Mak ACY, Perez-Garcia J, Elhawary JR, Oh SS, Hu D, Eng C, Keys KL, Huntsman S, Beckman KB, Borrell LN, Rodriguez-Santana J, Burchard EG, Pino-Yanes M. Epigenome-wide association study of lung function in Latino children and youth with asthma. Clin Epigenetics. 2022 Jan 15;14(1):9. doi: 10.1186/s13148-022-01227-5. PMID: 35033200; PMCID: PMC8760660.

Salas A, Beltrán-Flores S, Évora C, Reyes R, Montes de Oca F, Delgado A, Almeida TA. Stem Cell Growth and Differentiation in Organ Culture: New Insights for Uterine Fibroid Treatment. Biomedicines. 2022 Jun 29;10(7):1542. doi: 10.3390/biomedicines10071542. PMID: 35884847; PMCID: PMC9313456. 

Salas A, García-García P, Díaz-Rodríguez P, Évora C, Almeida TA, Delgado A. New local ganirelix sustained release therapy for uterine leiomyoma. Evaluation in a preclinical organ model. Biomed Pharmacother. 2022 Dec;156:113909. doi: 10.1016/j.biopha.2022.113909. Epub 2022 Oct 21. PMID: 36279721.

Espuela-Ortiz A, Herrera-Luis E, Lorenzo-Díaz F, Hu D, Eng C, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M. Role of Sex on the Genetic Susceptibility to Childhood Asthma in Latinos and African Americans. J Pers Med. 2021 Nov 3;11(11):1140. doi: 10.3390/jpm11111140. PMID: 34834492; PMCID: PMC8625344.

Ortega VE, Daya M, Szefler SJ, Bleecker ER, Chinchilli VM, Phipatanakul W, Mauger D, Martinez FD, Herrera-Luis E, Pino-Yanes M, Hawkins GA, Ampleford EJ, Kunselman SJ, Cox C, Bacharier LB, Cabana MD, Cardet JC, Castro M, Denlinger LC, Eng C, Fitzpatrick AM, Holguin F, Hu D, Jackson DJ, Jarjour N, Kraft M, Krishnan JA, Lazarus SC, Lemanske RF Jr, Lima JJ, Lugogo N, Mak A, Moore WC, Naureckas ET, Peters SP, Pongracic JA, Sajuthi SP, Seibold MA, Smith LJ, Solway J, Sorkness CA, Wenzel S, White SR, Burchard EG, Barnes K, Meyers DA, Israel E, Wechsler ME; NHLBI AsthmaNet. Pharmacogenetic studies of long-acting beta agonist and inhaled corticosteroid responsiveness in randomised controlled trials of individuals of African descent with asthma. Lancet Child Adolesc Health. 2021 Dec;5(12):862-872. doi: 10.1016/S2352-4642(21)00268-6. Epub 2021 Nov 9. PMID: 34762840; PMCID: PMC8787857.

Maroteau C, Espuela-Ortiz A, Herrera-Luis E, Srinivasan S, Carr F, Tavendale R, Wilson K, Hernandez-Pacheco N, Chalmers JD, Turner S, Mukhopadhyay S, Maitland-van der Zee AH, Burchard EG, Pino-Yanes M, Young S, Lassi G, Platt A, Palmer CNA; PiCA Consortium. LTA4H rs2660845 association with montelukast response in early and late-onset asthma. PLoS One. 2021 Sep 22;16(9):e0257396. doi: 10.1371/journal.pone.0257396. PMID: 34550981; PMCID: PMC8457475.

Kan M, Diwadkar AR, Shuai H, Joo J, Wang AL, Ong MS, Sordillo JE, Iribarren C, Lu MX, Hernandez-Pacheco N, Perez-Garcia J, Gorenjak M, Potočnik U, Burchard EG, Pino-Yanes M, Wu AC, Himes BE. Multiomics analysis identifies BIRC3 as a novel glucocorticoid response-associated gene. J Allergy Clin Immunol. 2022 Jun;149(6):1981-1991. doi: 10.1016/j.jaci.2021.11.025. Epub 2021 Dec 28. PMID: 34971648; PMCID: PMC9177524.

Hernandez-Pacheco N, Gorenjak M, Li J, Repnik K, Vijverberg SJ, Berce V, Jorgensen A, Karimi L, Schieck M, Samedy-Bates LA, Tavendale R, Villar J, Mukhopadhyay S, Pirmohamed M, Verhamme KMC, Kabesch M, Hawcutt DB, Turner S, Palmer CNA, Burchard EG, Tantisira KG, Maitland-van der Zee AH, Flores C, Potočnik U, Pino-Yanes M. Identification of ROBO2 as a Potential Locus Associated with Inhaled Corticosteroid Response in Childhood Asthma. Journal of Personalized Medicine. 2021;11(8):733.

Karimi L, Vijverberg SJ, Engelkes M, Hernandez-Pacheco N, Farzan N, Soares P, Pino-Yanes M, Jorgensen AL, Eng C, Mukhopadhyay M, Schieck M, Kabesch M, Burchard EG, Chew FT, Sio YY, Potočnik U, Gorenjak M, Hawcutt DB, Palmer CN, Turner S, Janssens HM, Maitland-van der Zee AH, Verhamme KMC, PiCA and SysPharmPedia consortia. ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta-analysis. Clinical and Experimental Allergy. 2021;51(9):1157-1171.

Slob EMA, Richards LB, Vijverberg SJH, Longo C, Koppelman GH, Pijnenburg MWH, Bel EHD, Neerincx AH, Herrera Luis E, Perez-Garcia J, Tim Chew F, Yie Sio Y, Andiappan AK, Turner SW, Mukhopadhyay S, Palmer CNA, Hawcutt D, Jorgensen AL, Burchard EG, Hernandez-Pacheco N, Pino-Yanes M, Maitland-van der Zee AH. Genome-wide association studies of exacerbations in children using long-acting beta2-agonists. Pediatr Allergy Immunol. 2021;32(6):1197-1207.

Abdel-Aziz MI, Neerincx AH, Vijverberg SJH, Hashimoto S, Brinkman P, Gorenjak M, Toncheva AA, Harner S, Brandstetter S, Wolff C, Perez-Garcia J, Hedman AM, Almqvist C, Corcuera-Elosegui P, Korta-Murua J, Sardón-Prado O, Pino-Yanes M, Potočnik U, Kabesch M, Kraneveld AD, Maitland-van der Zee AH, On Behalf Of The SysPharmPediA Consortium. A System Pharmacology Multi-Omics Approach toward Uncontrolled Pediatric Asthma. J Pers Med. 2021;11(6):484.

Garcillán-Barcia MP, Pluta R, Lorenzo-Díaz F, Bravo A, Espinosa M. The Facts and Family Secrets of Plasmids That Replicate via the Rolling-Circle Mechanism. Microbiol Mol Biol Rev. 2022 Mar 16;86(1):e0022220. doi: 10.1128/MMBR.00222-20. Epub 2021 Dec 8. PMID: 34878299; PMCID: PMC8653906.

Gómez I, López MC, Rastrojo A, Lorenzo-Díaz F, Requena JM, Aguado B, Valladares B, Thomas MC. Variability of the Pr77 sequence of L1Tc retrotransposon among six T. cruzi strains belonging to different discrete typing units (DTUs). Acta Trop. 2021 Oct;222:106053. doi: 10.1016/j.actatropica.2021.106053. Epub 2021 Jul 15. PMID: 34273311.

Solano-Collado V, Ruiz-Cruz S, Lorenzo-Díaz F, Pluta R, Espinosa M, Bravo A. Recognition of Streptococcal Promoters by the Pneumococcal SigA Protein. Front Mol Biosci. 2021 Jun 24;8:666504. doi: 10.3389/fmolb.2021.666504. PMID: 34250014; PMCID: PMC8264293.

Hernandez-Pacheco N, Vijverberg SJ, Herrera-Luis E, Li J, Sio YY, Granell R, Corrales A, Maroteau C, Lethem R, Perez-Garcia J, Farzan N, Repnik K, Gorenjak M, Soares P, Karimi L, Schieck M, Pérez-Méndez L, Berce V, Tavendale R, Eng C, Sardon O, Kull I, Mukhopadhyay S, Pirmohamed M, Verhamme KMC, Burchard EG, Kabesch M, Hawcutt DB, Melén E, Potočnik U, Chew FT, Tantisira KG, Turner S, Palmer CN, Flores C, Pino-Yanes M, Maitland-van der Zee AH, PiCA and SysPharmPedia consortia. Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use. Eur Respir. 2021;57(5):2003388.

Salas A, Vázquez P, Bello AR, Báez D, Almeida TA. Dual agonist-antagonist effect of ulipristal acetate in human endometrium and myometrium. Expert Rev Mol Diagn. 2021 Aug;21(8):851-857. doi: 10.1080/14737159.2021.1941878. Epub 2021 Jun 24. PMID: 34110938.

Perez-Garcia J, Hernández-Pérez JM, González-Pérez R, Sardón O, Martin-Gonzalez E, Espuela-Ortiz A, Mederos-Luis E, Callero A, Herrera-Luis E, Corcuera P, Sánchez-Machín I, Poza-Guedes P, González García LM, Ramírez-Martín P, Pérez-Negrín L, Izaguirre-Flores H, Barrios-Recio J, Pérez-Rodríguez E, Alcoba-Florez J, Cañas JA, Rodrigo Muñoz JM, del Pozo V, Korta-Murua J, Pérez Méndez LI, Hernandez-Ferrer M, Villar J, Lorenzo-Diaz F, Pino-Yanes M. The Genomics and Metagenomics of Asthma Severity (GEMAS) Study: Rationale and Design. J Pers Med. 2020; 10(3): 123.

Yan Q, Forno E, Herrera-Luis E, Pino-Yanes M, Yang G, Oh S, Acosta-Pérez E, Hu D, Eng C, Huntsman S, Rodriguez-Santana JR, Cloutier MM, Canino G, Burchard EG, Chen W, Celedón JC. A genome-wide association study of asthma hospitalizations in adults. J Allergy Clin Immunol. 2020; in press.

Herrera-Luis E, Espuela-Ortiz A, Lorenzo-Diaz F, Keys KL, Mak ACY, Eng C, Huntsman S, Villar J, Rodriguez-Santana JR, Burchard EG, Pino-Yanes M. Genome-wide association study reveals a novel locus for asthma with severe exacerbations in diverse populations. Pediatr Allergy Immunol. 2020; in press.

Jiang Y, Forno E, Han YY, Xu Z, Hu D, Boutaoui N, Eng C, Acosta-Pérez E, Huntsman S, Colón-Semidey A, Keys KL, Rodríguez-Santana JR, Alvarez M, Pino-Yanes M, Canino G, Chen W, Burchard EG, Celedón JC. A genome-wide study of DNA methylation in white blood cells and asthma in Latino children and youth. Epigenetics. 2020;1:1-9.

Hernandez-Pacheco N*, Gorenjak M*, Jurgec S, Corrales A, Jorgensen A, Karimi L, Vijverberg SJ, Berce V, Schieck M, Acosta-Herrera M, Kerick M, Samedy-Bates LA, Tavendale R, Villar J, Mukhopadhyay S, Pirmohamed M, Mc Verhamme K, Kabesch M, Hawcutt DB, Turner S, Palmer CN, Burchard EG, Maitland-van der Zee AH, Flores C, Potočnik U, Pino-Yanes M; PiCA, SysPharmPedia consortia. Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma. Allergy. 2020;76:1238-1243.

Early Bacterial Colonization and Antibiotic Resistance Gene Acquisition in Newborns. Klassert TE, Zubiria-Barrera C, Kankel S, Stock M, Neubert R, Lorenzo-Diaz F, Doehring N, Driesch D, Fischer D, Slevogt H. Front Cell Infect Microbiol. 2020;10:332.

Gómez I, Rastrojo A, Lorenzo-Díaz F, Sánchez-Luque FJ, Macías F, Aguado B, Valladares B, Requena JM, López MC, Thomas MC. Trypanosoma cruzi Ikiakarora (TcIII) Draft Genome Sequence. Microbiol Resour Announc. 2020;9(27):e00453-20. 

Gómez I, Rastrojo A, Sanchez-Luque FJ, Lorenzo-Díaz F, Macías F, Valladares B, Aguado B, Requena JM, López MC, Thomas MC. Draft Genome Sequence of the Trypanosoma cruzi B. M. López Strain (TcIa), Isolated from a Colombian Patient. Microbiol Resour Announc. 2020;9(18):e00031-20.

Hernández-Pérez JM, Martín-González E, Pino-Yanes M. Virtudes y dificultades en los test diagnósticos de la infección por el SARS-CoV-2. Med Clin (Barc). 2020;S0025-7753(20)30346-8. 

Perez-Garcia J, Herrera-Luis E, Lorenzo-Diaz F, González M, Sardón O, Villar J, Pino-Yanes M. Precision Medicine in Childhood Asthma: Omic Studies of Treatment Response. Int J Mol Sci. 2020;21(8):E2908.

Perez-Garcia J, Espuela-Ortiz A, Lorenzo-Diaz F, Pino-Yanes M. Pharmacogenetics of Pediatric Asthma: Current Perspectives. Pharmgenomics Pers Med. 2020;13:89–103.

Guillen-Guio B, Hernández-Beeftink T, Marcelino-Rodríguez I, Rodríguez-Pérez H, Lorenzo-Salazar JM, Espinilla-Peña M, Corrales A, Pino-Yanes M, Callero A, Perez-Rodriguez E, Villar J, González-Montelongo R, Flores C. Admixture mapping of asthma in southwestern Europeans with North African ancestry influences. Am J Physiol Lung Cell Mol Physiol. 2020;318(5):L965-L975.

King C, McKenna A, Farzan N, Vijverberg SJ, van der Schee MP, Maitland-van der Zee AH, Arianto L, Bisgaard H, BØnnelykke K, Berce V, Potočnik U, Repnik K, Carleton B, Daley D, Chew FT, Chiang WC, Sio YY, Cloutier MM, Den Dekker HT, Duijts L, de Jongste JC, Dijk FN, Koppelman GH, Flores C, Hernandez-Pacheco N, Mukhopadhyay S, Basu K, Bignell L, Tantisira KG, Turner S, Verhamme KM, Francis B, Pirmohamed M, Sinha I, Hawcutt DB. Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation. Pharmacogenomics J. 2020; in press.

Salas A, López J, Reyes R, Évora C, de Oca FM, Báez D, Delgado A, Almeida TA. Organotypic culture as a research and preclinical model to study uterine leiomyomas. Sci Rep. 2020 Mar 23;10(1):5212. doi: 10.1038/s41598-020-62158-w. PMID: 32251338; PMCID: PMC7090073.

Dijk FN, Vijverberg SJ, Hernandez-Pacheco N, Repnik K, Karimi L, Mitratza M, Farzan N, Nawijn MC, Burchard EG, Engelkes M, Verhamme KM, Potočnik U, Pino-Yanes M, Postma DS, Maitland-van der Zee AH, Koppelman GH. IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids. Allergy. 75(4); 2019.

Lorenzo-Diaz F, Moreno-Córdoba I, Espinosa M. Complete labelling of pneumococcal DNA-binding proteins with seleno-L-methionine. J Microbiol Methods. 166; 2019.

Espuela-Ortiz A, Lorenzo-Diaz F, Baez-Ortega A, Eng C, Hernandez-Pacheco N, Oh SS, Lenoir M, Burchard EG, Flores C, Pino-Yanes M. Bacterial Salivary Microbiome Associates with Asthma among African American children and young adults. Pediatr Pulmonol. 54(12); 2019.

Lona-Durazo F, Hernandez-Pacheco N, Fan S, Zhang T, Choi J, Kovacs MA, Loftus SK, Le P, Edwards M, Fortes-Lima CA, Eng C, Huntsman S, Hu D, Gómez-Cabezas EJ, Marín-Padrón LC, Grauholm J, Mors O, Burchard EG, Norton HL, Pavan WJ, Brown KM, Tishkoff S, Pino-Yanes M, Beleza S, Marcheco-Teruel B, Parra EJ. Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations. BMC Genet. 20(1); 2019.

Samedy-Bates LA, Oh SS, Nuckton TJ, Elhawary JR, White M, Elliot T, Zeiger AM, Eng C, Salazar S, LeNoir MA, Meade K, Farber HJ, Serebrisky D, Brigino-Buenaventura E, Rodriguez-Cintron W, Bibbins-Domingo K, Kumar R, Thyne S, Borrell LN, Rodriguez-Santana JR, Pino-Yanes M, Burchard EG. Racial/ethnic-specific differences in the effects of inhaled corticosteroid use on bronchodilator response in patients with asthma. Clin Pharmacol Ther. 106(5); 2019.

Hernandez-Pacheco N, Farzan N, Francis B, Karimi L, Repnik K, Vijverberg SJ, Soares P, Schieck M, Gorenjak M, Forno E, Eng C, S Oh S, Pérez-Méndez L, Berce V, Tavendale R, Samedy LA, Hunstman S, Hu D, Meade K, Farber HJ, Avila PC, Serebrisky D, Thyne SM, Brigino-Buenaventura E, Rodriguez-Cintron W, Sen S, Kumar R, Lenoir M, Rodriguez-Santana JR, Celedón JC, Mukhopadhyay S, Potočnik U, Pirmohamed M, Verhamme KM, Kabesch M, Palmer CNA, Hawcutt DB, Flores C, Maitland  van der Zee AH, Burchard EG, Pino-Yanes M* (*Corresponding author). Genome-wide association study of inhaled corticosteroid response in admixed children with asthma. Clin Exp Allergy. 49(6); 2019.

Hernandez-Pacheco N, Pino-Yanes M*, Flores C (*Corresponding author). Genomic predictors of asthma phenotypes and treatment response. Front Pediatr. 7; 2019.

Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, Acevedo N, Araujo MI, Avila PC, Belbin G, Bleecker E, Bustamante C, Caraballo L, Cruz A, Dunston GM, Eng C, Faruque MU, Ferguson TS, Figueiredo C, Ford JG, Gan W, Gourraud PA, Hansel NN, Hernandez RD, Herrera-Paz  EF, Jiménez S, Kenny EE, Knight-Madden J, Kumar R, Lange LA, Lange EM, Lizee A, Maul P, Maul T, Mayorga A, Meyers D, Nicolae DL, O'Connor TD, Oliveira RR, Olopade CO, Olopade O, Qin ZS, Rotimi C, Vince N, Watson H, Wilks RJ, Wilson JG, Salzberg S, Ober C, Burchard EG, Williams LK, Beaty TH, Taub MA, Ruczinski I, Mathias RA, Barnes KC, Adegnika AA, Arinola G, Ateba-Ngoa U, Ayestas G, Bjarnadóttir H, Correa A, Erazo SOL, Foreman MG, Foster C, Gao L, Gao J, Grammer L, Hansen M, Hartert T, Hu Y, Königsberg I, Kim KA, Landaverde-Torres P, Marrugo J, Martinez B, Martinez R, Mayorga LF, Mejia-Mejia DA, Meza C, Musani S, Musharoff S, Oluwole O, Pino-Yanes M, Ramos H, Saenz A, Samms-Vaughan M, Schleimer R, Scott AF, Shringarpure SS, Song W, Szpiech ZA, Torres R, Varela G, Vasquez OM, Vega FM, Ware LB, Yazdanbakhsh M. Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. Nat Commun. 10(1); 2019.

Almoguera B; Vazquez L; Mentch F; March ME; Connolly JJ; Peissig PL; Linneman JG; Plaza-Serón MDC; Pino-Yanes M; Burchard EG; Brilliant M; Sleiman P; Hakonarson H. Novel locus for atopic dermatitis in African Americans and replication in European Americans. J Allergy Clin Immunol. 143 (3); 2019.

Herrera-Luis E, Hernandez-Pacheco N, Vijverberg SJ, Flores C, Pino-Yanes M. Role of genomics in asthma exacerbations. Curr Opin Pulm Med. 25 (1); 2019.

Levin AM, Gui H, Hernandez-Pacheco N, Yang M, Xiao S, Yang JJ, Hochstadt S, Barczak AJ, Eckalbar WL, Rynkowski D, Samedy LA, Kwok PY, Pino-Yanes M, Erle DJ, Lanfear DE, Burchard EG, Williams LK. Integrative approach identifies corticosteroid response variant in diverse populations with asthma. J Allergy Clin Immunol. 143 (5); 2019.

Gignoux CR, Torgerson DG, Pino-Yanes M, Uricchio LH, Galanter J, Roth LA, Eng C, Hu D, Nguyen EA, Huntsman S, Mathias RA, Kumar R, Rodriguez-Santana J, Thakur N, Oh SS, McGarry M, Moreno-Estrada A, Sandoval K, Winkler CA, Seibold MA, Padhukasahasram B, Conti DV, Farber HJ, Avila P, Brigino-Buenaventura E, Lenoir M, Meade K, Serebrisky D, Borrell LN, Rodriguez-Cintron W, Thyne S, Joubert BR, Romieu I, Levin AM, Sienra-Monge JJ, Del Rio-Navarro BE, Gan W, Raby BA, Weiss ST, Bleecker E, Meyers DA, Martinez FJ, Gauderman WJ, Gilliland F, London SJ, Bustamante CD, Nicolae DL, Ober C, Sen S, Barnes K, Williams LK, Hernandez RD, Burchard EG. An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos. J Allergy Clin Immunol. 143 (3); 2019.

Spear ML, Hu D, Pino-Yanes M, Huntsman S, Eng C, Levin AM, Ortega VE, White MJ, McGarry ME, Thakur N, Galanter J, Mak ACY, Oh SS, Ampleford E, Peters SP, Davis A, Kumar R, Farber HJ, Meade K, Avila PC, Serebrisky D, Lenoir MA, Brigino-Buenaventura E, Cintron WR, Thyne SM, Rodriguez-Santana JR, Ford JG, Chapela R, Estrada AM, Sandoval K, Seibold MA, Winkler CA, Bleecker ER, Myers DA, Williams LK, Hernandez RD, Torgerson DG, Burchard. EGA genome-wide association and admixture mapping study of bronchodilator drug response in African Americans with asthma. Pharmacogenomics J. 19 (3); 2019.

Hernández M, Martín MV, Herrador-Gómez PM, Jiménez S, Hernández-González C, Barreiro S, Sarralde R, van Zyl BJ, Gamatham JC, Almeida T, López-Abellán LJ. Mitocondrial COI and 16S rDNA sequences support morphological identification and biogeography of deep-sea red crabs of the genus Chaceon (Crustacea, Decapoda, Geryonidae) in the Eastern Central and South Atlantic Ocean. PLoS One. 2019 Feb 11;14(2):e0211717. doi: 10.1371/journal.pone.0211717. PMID: 30742637; PMCID: PMC6370203.

Hernandez-Pacheco N, Guillen-Guio B, Acosta-Herrera M, Pino-Yanes M, Corrales A, Ambrós A, Nogales; GEN-SEP Network. A vascular endothelial growth factor receptor gene variant is associated with susceptibility to acute respiratory distress syndrome. Intensive Care Med Exp. 6 (1); 2018.

Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N; 23andMe Research Team; AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, Arnold A, Barreto-Luis A, Baurecht H, van Beijsterveldt CEM, Bleecker ER, Bonàs-Guarch S, Boomsma DI, Brix S, Bunyavanich S, Burchard EG, Chen Z, Curjuric I, Custovic A, den Dekker HT, Dharmage SC, Dmitrieva J, Duijts L, Ege MJ, Gauderman WJ, Georges M, Gieger C, Gilliland F, Granell R, Gui H, Hansen T, Heinrich J, Henderson J, Hernandez-Pacheco N, Holt P, Imboden M, Jaddoe VWV, Jarvelin MR, Jarvis DL, Jensen KK, Jónsdóttir I, Kabesch M, Kaprio J, Kumar A, Lee YA, Levin AM, Li X, Lorenzo-Diaz F, Melén E, Mercader JM, Meyers DA, Myers R, Nicolae DL, Nohr EA, Palviainen T, Paternoster L, Pennell CE, Pershagen G, Pino-Yanes M, Probst-Hensch NM, Rüschendorf F, Simpson A, Stefansson K, Sunyer J, Sveinbjornsson G, Thiering E, Thompson PJ, Torrent M, Torrents D, Tung JY, Wang CA, Weidinger S, Weiss S, Willemsen G, Williams LK, Ober C, Hinds DA, Ferreira MA, Bisgaard H, Strachan DP, Bønnelykke K. Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. Nat Genet. 50 (9); 2018.

Sun X, Gao J, Jin P, Eng C, Burchard EG, Beaty TH, Ruczinski I, Mathias RA, Barnes K, Wang F, Qin ZS; CAAPA consortium. Optimized distributed systems achieve significant performance improvement on sorted merging of massive VCF files. Gigascience. 7 (6); 2018.

Turner S; Francis B; Wani N; Vijverberg S; Pino-Yanes M; Mukhopadhyay S; Tavendale R; Palmer C; Burchard EG; Merid SK; Melén E; Maitland-van der Zee AH; The Pharmacogenomics In Childhood Asthma Consortium. Variants in genes coding for glutathione S-transferases and asthma outcomes in children. Pharmacogenomics. 19 (8); 2018.

Farzan N, Vijverberg SJ, Hernandez-Pacheco N, Bel EHD, Berce V, Bønnelykke K, Bisgaard H, Burchard EG, Canino G, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Forno E, Francis B, Hawcutt DB, Herrera-Luis E, Kabesch M, Karimi L, Melén E, Mukhopadhyay S, Merid SK, Palmer CN, Pino-Yanes M, Pirmohamed M, Potočnik U, Repnik K, Schieck M, Sevelsted A, Sio YY, Smyth RL, Soares P, Söderhäll C, Tantisira KG, Tavendale R, Tse SM, Turner S, Verhamme KM, Maitland-van der Zee AH. 17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use. Allergy. 73 (10); 2018.

Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galant; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. Am J Respir Crit Care Med. 197 (12); 2018.

Fabian Lorenzo-Díaz; Cris Fernández-López; Beatriz Guillén-Guío; Alicia Bravo; Manuel Espinosa. Relaxase MobM Induces a Molecular Switch at Its Cognate Origin of Transfer. Front Mol Biosci. 5 (17); 2018.

Galindo LJ, Hernández-Beeftink T, Salas A, Jung Y, Reyes R, de Oca FM, Hernández M, Almeida TA. HMGA2 and MED12 alterations frequently co-occur in uterine leiomyomas. Gynecol Oncol. 2018 Sep;150(3):562-568. doi: 10.1016/j.ygyno.2018.07.007. Epub 2018 Jul 13. PMID: 30017537.

Yan Q; Brehm J; Pino-Yanes M; Forno E; Lin J; Oh S; Acosta-Perez E; Laurie C; Cloutier M; Raby B; Stilp A; Sofer T; Hu D; Eng C; Huntsman S; Conomos M; Rastogi D; Rice K; Canino G; Chen W; Barr R G; Burchard E; Celedon JC. A meta-analysis of genome-wide association studies of asthma in Puerto Ricans. European Respiratory. Journal. 49 (5); 2017.

Barreto-Luis A; Corrales A; Acosta-Herrera M; Gonzalez-Colino C; Cumplido J; Martinez-Tadeo J; Carracedo A; Villar J; Carrillo T; Pino-Yanes M; Flores C. A pathway-based association study reveals variants from Wnt signaling genes contributing to asthma susceptibility. Clinical & Experimental Allergy. 47 (5); 2017.

Ruben Jiménez-Canino; Fabian Lorenzo-Díaz; A Odermatt; MA Bailey; DEW Livingstone; F Jaisser; N Farman; Diego Alvarez de la Rosa. 11β-HSD2 SUMOylation Modulates Cortisol-induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation. Endocrinology. 158 (11); 2017.

Chen W; Wang T; Pino-Yanes M; Forno E; Liang L; Yan Q; Hu D; Weeks DE; Baccarelli A; Acosta-Perez E; Eng C; Han Y-Y; Boutaoui N; Laprise C; Davies GA; Hopkin JM; Moffatt MF; Cookson WOCM; Canino G; Burchard EG; Celedón JC. An epigenome-wide association study of total serum immunoglobulin E in Hispanic children. J Allergy Clin Immunol. 140 (2); 2017.

Oh SS; Du R; Zeiger AM; McGarry ME; Hu D; Thakur N; Pino-Yanes M; Galanter JM; Eng C; Nishimura KK; Huntsman S; Farber HJ; Meade K; Avila P; Serebrisky D; Bibbins-Domingo K; Lenoir MA; Ford JG; Brigino-Buenaventura E; Rodriguez-Cintron W; Thyne SM; Sen S; Rodriguez-Santana JR; Williams K; Kumar R; Burchard EG. Breastfeeding associated with higher lung function in African American youths with asthma. J Asthma. 24 (8); 2017.

Joshua M Galanter; Christopher R Gignoux; Sam S Oh; Dara Torgerson; Maria Pino Yanes; Neeta Thakur; Celeste Eng; Donglei Hu; Scott Huntsman; Harold J Farber; Pedro C Avila; Emerita Brigino Buenaventura; Michael A LeNoir; Kelly Meade; Denise Serebrisky; William Rodríguez Cintrón; Rajesh Kumar; Jose R Rodríguez Santana; Max A Seibold; Luisa N Borrell; Esteban G Burchard; Noah Zaitlen. Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures. ELife. 6; 2017.

Fabian Lorenzo-Díaz; Cris Fernández-López; Rudi Lurz; Alicia Bravo; Manuel Espinosa. Crosstalk between vertical and horizontal gene transfer: plasmid replication control by a conjugative relaxase. Nucleic Acids Res. 45 (13); 2017.

Hernandez-Pacheco N; Flores C; Alonso S; Eng C; Mak ACY; Hunstman S; Hu D; White MJ; Oh SS; Meade K; Farber HJ; Avila PC; Serebrisky D; Thyne SM; Brigino-Buenaventura E; Rodriguez-Cintron W; Sen S; Kumar R; Lenoir M; Rodriguez-Santana JR; Burchard EG; Pino-Yanes M. Identification of a novel locus associated with skin colour in African-admixed populations. Scientific Reports. 7; 2017.

Shringarpure SS, Mathias RA, Hernandez RD, O'Connor TD, Szpiech ZA, Torres R, De La Vega FM, Bustamante CD, Barnes KC, Taub MA; CAAPA Consortium. Using genotype array data to compare multi- and single-sample variant calls and improve variant call sets from deep coverage whole-genome sequencing data. Bioinformatics. 33 (8); 2017.

Johnston HR, Hu YJ, Gao J, O'Connor TD, Abecasis GR, Wojcik GL, Gignoux CR, Gourraud PA, Lizee A, Hansen M, Genuario R, Bullis D, Lawley C, Kenny EE, Bustamante C, Beaty TH, Mathias RA, Barnes KC, Qin ZS; CAAPA Consortium (91 authors, including Pino-Yanes M). Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome. Scientifics Reports. 7; 2017.

Radeck Pluta; Roeland D Boer; Fabian Lorenzo-Díaz; Silvia Russi; H Gómez; Cris Fernández-López; Rosa Pérez-Luque; Modesto Orozco; Manuel Espinosa; Miquel Coll. Structural basis of a histidine-DNA nicking/joining mechanism for gene transfer and promiscuous spread of antibiotic resistance. Proc Natl Acad Sci U S A. 114 (32); 2017.

Farzan N; Vijverberg SJ; Andiappan AK; Arianto L; Berce V; Blanca-López N; Bisgaard H; Bønnelykke K; Burchard EG; Campo P; Canino G; Carleton B; Celedón JC; Chew FT; Chiang WC; Cloutier MM; Daley D; Den Dekker HT; Dijk FN; Duijts L; Flores C; Forno E; Hawcutt DB; Hernandez-Pacheco N; de Jongste JC; Kabesch M; Koppelman GH; Manolopoulos VG; Melén E; Mukhopadhyay S; Nilsson S; Palmer CN; Pino-Yanes M; Pirmohamed M; Potočnik U; Raaijmakers JA; Repnik K; Schieck M; Sio YY; Smyth RL; Szalai C; Tantisira KG; Turner S; van der Schee MP; Verhamme KM; Maitland-van der Zee AH. Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium. Pharmacogenomics. 18(10); 2017.

Marques C; Costa G; da Silva T; Oliveira PR; Cruz A; Alcantara-Neves N; Fiaccone R; Horta B; Hartwig F; Burchard E; Pino-Yanes M; Rodrigues L; Lima-Costa MF; Pereira A; Gouveia M; Sant-Anna HS; Tarazona-Santos E; Barreto M; Figueiredo C. Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children. European Journal of Human Genetics. 25 (4); 2017.

Mathias, R.; Taub, M.; Gignoux, C.; Fu, W.; Musharoff, S; O'Connor, T.; Vergara, C.; Torgerson, D.; Pino-Yanes, M.; Shringarpure, S.; Huang, L.; Rafaels, N.; Boorgula, M.; Johnston, H.; Ortega, V.; Levin, A.; Song, W.; Torres, R.; Padhukasahasram, B.; Eng, C.; Mejia-Mejia, D-A.; Ferguson,T.; Qin, Z.; Scott, A.; Yazdanbakhsh, M.; Wilson, J.; Marrugo, J.; Lange, L.; Kumar, R.; Avila, A.; Williams, L.K.; Watson, H.; Ware, L.; Olopade, C.; Olopade, O.; Oliveira, R.; Ober, C.; Nicolae, D.; Meyers, D.; Mayorga, A.; Knight-Madden, J.; Hartert, T.; Hansel, N.; Foreman, M.; Ford, J.; Faruque, M.; Dunston, G.; Caraballo, L.; Burchard, E.; Bleecker, E.; Araujo, M.; Herrera-Paz, E.; Gietzen, K.; Grus, W.; Bamshad, M.; Bustamante, C.; Kenny, E.; Hernandez, R.; Beaty, T.; Ruczinski, I.; Akey, J.; Barnes, K. A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nature Communications. 7; 2016.

Andreas M Neophytou; Marquitta J White; Sam S Oh; Neeta Thakur; Joshua M Galanter; Katherine K Nishimura; Maria Pino Yanes; Dara G Torgerson; Christopher R Gignoux; Celeste Eng; Elizabeth A Nguyen; Donglei Hu; Angel C Mak; Rajesh Kumar; Max A Seibold; Adam Davis; Harold J Farber; Kelley Meade; Pedro C Avila; Denise Serebrisky; Michael A Lenoir; Emerita Brigino Buenaventura; William Rodriguez Cintron; Kirsten Bibbins Domingo; Shannon M Thyne; L Keoki Williams; Saunak Sen; Frank D Gilliland; W James Gauderman; Jose R Rodriguez Santana; Fred Lurmann; John R Balmes; Ellen A Eisen; Esteban G Burchard. Air Pollution and Lung Function in Minority Youth with Asthma in the GALA II & SAGE II Studies. American Journal of Respiratory and Critical Care Medicine. 193 (11); 2016.

Ruben Jimenez Canino; Fabian Lorenzo-Diaz; Friederic Jaisser; Nicolette Farman; Teresa Giraldez; Diego Alvarez de la Rosa. Histone Deacetylase 6-Controlled Hsp90 Acetylation Significantly Alters Mineralocorticoid Receptor Subcellular Dynamics But Not its Transcriptional Activity. Endocrinology. 157 (6); 2016.

Seong H Cho; Jin-Young Min; Dong Young Kim; Sam S Oh; Dara R Torgerson; Maria Pino Yanes; Donglei Hu; Saunak Sen; Scott Huntsman; Celeste Eng; Harold J Farber; William Rodriguez Cintron; Jose R Rodriguez Santana; Denise Serebrisky; Shannon M Thyne; Luisa N Borrell; L Keoki Williams; William DuPont; Max A Seibold; Esteban G Burchard; Pedro C Avila; Rajesh Kumar. Association of a PAI-1 Gene Polymorphism and Early Life Infections with Asthma Risk, Exacerbations, and Reduced Lung Function. PLOS ONE. 11 (8); 2016.

Michael D. Kessler; Laura Yerges-Armstrong; Margaret A. Taub; Amol C. Shetty; Kristin Maloney; Linda Jo Bone Jeng; Ingo Ruczinski; Albert M. Levin; L. Keoki Williams; Terri H. Beaty; Rasika A. Mathias; Kathleen C. Barnes; Meher Preethi Boorgula; Monica Campbell; Sameer Chavan; Jean G. Ford; Cassandra Foster; Li Gao; Nadia N. Hansel; Edward Horowitz; Lili Huang; Romina Ortiz; Joseph Potee; Nicholas Rafaels; Alan F. Scott; Candelaria Vergara; Jingjing Gao; Yijuan Hu; Henry Richard Johnston; Zhaohui S. Qin; Badri M. Dunston;  Mezbah U. Faruque; Eimear E. Kenny; Kimberly Gietzen; Mark Hansen; Rob Genuario; Dave Bullis; Cindy Lawley; Aniket Deshpande; Wendy E. Grus; Devin P. Locke; Marilyn G. Foreman; Pedro C. Avila; Leslie Grammer; Kwang-YounA Kim; Rajesh Kumar; Robert Schleimer; Carlos Bustamante; Francisco M. De La Vega; Chris R. Gignoux; Suyash S. Shringarpure; Shaila Musharoff; Genevieve Wojcik; Esteban G. Burchard; Celeste Eng; Pierre-Antoine Gourraud; Ryan D. Hernandez; Antoine Lizee; Maria Pino-Yanes; Dara G. Torgerson; Zachary A. Szpiech; Raul Torres; Dan L. Nicolae; Carole Ober; Christopher O. Olopade; Olufunmilayo Olopade; Oluwafemi Oluwole; Ganiyu Arinola; Wei Song; Goncalo Abecasis; Adolfo Correa; Solomon Musani; James G. Wilson; Leslie A. Lange; Joshua Akey; Michael Bamshad; Jessica Chong; Wenqing Fu; Deborah Nickerson; Alexander Reiner; Tina Hartert; Lorraine B. Ware; Eugene Bleecker; Deborah Meyers; Victor E. Ortega; Maul R. N. Pissamai; Maul R. N. Trevor; Harold Watson; Maria Ilma Araujo; Ricardo Riccio Oliveira;  Luis Caraballo; Javier Marrugo; Beatriz Martinez; Catherine Meza; Gerardo Ayestas; Edwin Francisco Herrera-Paz; Pamela Landaverde-Torres; Said Omar Leiva Erazo; Rosella Martinez; Alvaro Mayorga; Luis F. Mayorga; Delmy-Aracely Mejia-Mejia; Hector Ramos; Allan Saenz; Gloria Varela; Olga Marina Vasquez; Trevor Ferguson; Jennifer Knight-Madden; Maureen Samms-Vaughan; Rainford J. Wilks; Akim Adegnika; Ulysse Ateba-Ngoa Maria Yazdanbakhsh; Timothy D. O’Connor.  Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry. Nature Communications. 7; 2016.

Turner S; Francis B; Vijverberg S; Pino-Yanes M; Maitland-van der Zee AH; Basu K; Bignell L; Mukhopadhyay S; Tavendale R; Palmer C; Hawcutt D; Pirmohamed M; Burchard EG; Lipworth B. Childhood asthma exacerbations and the Arg-16 beta2 receptor polymorphism: a meta-analysis stratified by treatment. Journal of Allergy and Clinical Immunology. 138; 2016.

Nishimura K.; Iwanaga K.; Oh S.; Pino-Yanes M.; Eng C.; Keswani A. Roth L.A.; Nguyen E.A.; Thyne S.M.; Farber H.J.; Serebrisky D.; Davis A.; Meade K.; LeNoir M.A.; Rodriguez-Cintron W.; Borrell L.N.; Bibbins-Domingo K.; Lurmann F.; Sen S.; Rodriguez-Santana J.R.; Brigino-Buenaventura E.; Avila P.C.; Balmes J.R.; Kumar R.; Burchard E.G. Early-Life Ozone Exposure Associated with Asthma Without Sensitization in Latino Children. Journal of Allergy and Clinical Immunology. 138 (6); 2016.

Fabian Lorenzo-Diaz; Cris Fernandez-Lopez; Pierre-Emmanuel Douarre; Adrian Baez-Ortega; Carlos Flores; Philippe Glaser; Manuel Espinosa. Streptococcal Group B Integrative and Mobilizable Element IME-rpsI Encodes a Functional Relaxase Involved in its Transfer. Open Biology. 6 (10); 2016.

Plaza-Serón M.C.; Blanca-López N.; Doña I.; Acosta-Herrera M.; Pino-Yanes M.; Flores C.; Cornejo-García J.A.; Perkins J.R.; Molina A.; Torres M.J.; Blanca M.; Canto M.G.; Ayuso P. Genetic variants of thymic stromal lymphopoietin in nonsteroidal anti-inflammatory drugs induced urticaria/angioedema. International Archives of Allergy and Immunology. 169 (4); 2016.

Maria Pino Yanes*; Amalia Barreto Luis*; Almudena Corrales; Paloma Campo; Ariel Callero; Marialbert Acosta Herrera; José Cumplido; Shwu-Fan Ma; Juan Martinez Tadeo; Jesús Villar; Joe G N Garcia; Teresa Carrillo; Ángel Carracedo; Miguel Blanca; Carlos Flores; (*These authors contributed equally to this work). Genome-wide association study in Spanish identifies ADAM metallopeptidase with thrombospondin type 1 motif, 9 (ADAMTS9), as a novel asthma susceptibility gene. Journal of Allergy and Clinical Immunology. 137 (3); 2016.

White MJ; Risse-Adams O; Goddard P; Contreras MG; Adams J; Hu D; Eng C; Oh SS; Davis A; Meade K; Brigino-Buenaventura E; LeNoir MA; Bibbins-Domingo K; Pino-Yanes M; Burchard E. Novel genetic risk factors for asthma in African American children: Precision Medicine and the SAGE II Study. Immunogenetics. 68 (6-7); 2016.

Natalia Hernandez Pacheco; Carlos Flores; Sam S Oh; Esteban G Burchard; Maria Pino Yanes. What Ancestry Can Tell Us About the Genetic Origins of Inter-Ethnic Differences in Asthma Expression. Current allergy and asthma reports. 16 (8); 2016.

Lorente L, Martín MM, Almeida T, Pérez-Cejas A, Ramos L, Argueso M, Riaño-Ruiz M, Solé-Violán J, Hernández M. Serum Levels of Substance P and Mortality in Patients with a Severe Acute Ischemic Stroke. Int J Mol Sci. 2016 Jun 22;17(6):991. doi: 10.3390/ijms17060991. PMID: 27338372; PMCID: PMC4926519.

García-Ortega J, Pinto FM, Prados N, Bello AR, Almeida TA, Fernández-Sánchez M, Candenas L. Expression of Tachykinins and Tachykinin Receptors and Interaction with Kisspeptin in Human Granulosa and Cumulus Cells. Biol Reprod. 2016 Jun;94(6):124. doi: 10.1095/biolreprod.116.139881. Epub 2016 May 4. PMID: 27146034.

González-Santana A, Marrero-Hernández S, Dorta I, Hernández M, Pinto FM, Báez D, Bello AR, Candenas L, Almeida TA. Altered expression of the tachykinins substance P/neurokinin A/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 receptors in uterine leiomyomata. Fertil Steril. 2016 Nov;106(6):1521-1529. doi: 10.1016/j.fertnstert.2016.07.007. Epub 2016 Jul 25. PMID: 27456549.