2023

Fitzgerald, JE; Venable, RM; Pastor, RW; Lyman, E “Surface viscosities of lipid bilayers determined from equilibrium molecular dynamics simulations,” Biophys. J. 122:1094(2023)


Thakur, N; Ray, AP; Sharp, L; Jin, B; Duong, A; Pour, NG; Obeng, S; Wijesekara, AV; Gao, Z-G; McCurdy, CR; Jacobson, KA; Lyman, E; Eddy, MT “Anionic phospholipids control mechanisms of GPCR-G protein recognition” Nat. Comm. 14:794(2023)


Doktorova, M; Symons, JL; Zhang, X; Wang, H-Y; Schlegel, J; Lorent, J; Heberle, F; Sezgin, E; Lyman, E; Levental, K; Levental, I. “Cell membranes sustain phospholipoid imbalance via cholesterol asymmetry” under review. Preprint: www.biorxiv.org/content/10.1101/2023.07.30.551157v1


Winnikoff, et al. “Homeocurvature adaptation of phospholipids defines pressure specialization in deep sea invertebrates” under review.


Thakur, N.; Ray, A.P.; Lyman, E.; Gao; Z-G; Jacobson, K.A.; Eddy, M.T. “Membrane mimetic dependence of GPCR landscapes” under review. Preprint: www.biorxiv.org/content/10.1101/2023.10.16.562552v1 

2022

McGraw, C; Koretz, KS; Oseid, D; Lyman, E; Robinson, AS “Cholesterol dependent activity of the A2A adenosine receptor is modulated by the cholesterol consensus motif” Molecules 27:3529(2022)


Bryer, AJ; Reddy, T; Lyman, E; Perilla, JR “Full scale structural, mechanical, and dynamic properties of HIV-1 liposomes” PLoS Computational Biology 18:e1009781(2021)

2021

Leonard, A. and Lyman, E. “Activation of G-protein coupled receptors is thermodynamically linked to lipid solvation” Biophysical Journal 120:1777(2021) 

Chockanathan, U.; Crosier, EJW.; Waddle, S.; Lyman, E.; Gerkin, R.C.; Padmanabhan, K. “Changes in pairwise correlation during running reshape global network state in the main olfactory bulb” J. Neurophysiology 125:1612(2021) 

Beaven, A.H.; Arnarez, C.; Lyman, E.; Bennett, W.F.D.; Sodt, A.J. "Curvature energetics determined by alchemical simulation on four topologically distinct lipid phases" J. Phys. Chem B 125:1815 (2021) 

2020

Lyman, E.; Sodt, A.J. "Differential or curvature stress? Modus Vivendi" Biophys. J. 118:535 (2020)

Baral, S.; Levental, I.; Lyman, E. "Composition dependence of cholesterol flip-flop rates in physiological mixtures" Chem. Phys. Lip. 232:104967 (2020)

Lorent, J.H.; Ganesan, L.; Rivera-Longsworth, G.; Sezgin, E.; Levental, K.R.; Lyman, E.; Levental, I. “The molecular and structural asymmetry of the plasma membrane” Nature Chemical Biology 16:644 (2020) 

Baral, S.; Phillips, M.; Yan, H.; Avenso, J.; Gundlach, L.; Baumeier, B.; Lyman, E. “Ultrafast formation of the charge-transfer state of Prodan reveals unique aspects of the chromophore environment” J. Phys. Chem. B 124:2463 (2020) 

Dorrell, M.W.; Heberle, F.A.; Katsaras, J.; Lutz, M.; Lyman, E.; Sodt, A.J. “Laterally resolved small angle neutron scattering intensity from lipid bilayer simulations: An exact and limited range treatment” J. Chem. Theo. Comp. 16:5287 (2020) 

2019

McGraw, C.; Yang, L.;Levental, I. Lyman, E.; Skaja-Robinson, A. “Membrane cholesterol depletion reduces downstream signaling activity of the adenosine A2A receptor” BBA: Biomembranes 1861:760 (2019) 

Pinkwart, K.; Schneider, F.; Lukoseviciute, M.; Sauka-Spengler, T.; Lyman, E.; Eggeling, C.; Sezgin, E. “Nanoscale dynamics of cholesterol in the cell membrane” J. Biol. Chem. 294:12599  10.1074/jbc.RA119.009683 (2019) 

Yang, L.; Lyman, E. “Local enrichment of unsaturated chains around the A2A adenosine receptor” Biochemistry 58:4096  doi.org/10.1021/acs.biochem.9b00607 (2019) 

Zgorski, A.; Pastor, R.; Lyman, E. “Surface shear viscosity and interleaflet friction from nonequilibrium simulations of lipid bilayers” J. Chem. Theo. Comp. 15:6471 doi.org/10.1021/acs.jctc.9b00683 (2019) 

Ghysels, A.; Krämer, A.; Venable, R.M.; Teague Jr, W.R.; Lyman, E.; Gawrisch, K.; Pastor, R. “Permeability of Membranes in the Liquid Ordered and Liquid Disordered Phases” Nat. Comm. 10:5616 (2019)  

2018

Lyman, E.; Hsieh, C.-L.; Eggeling, C. “Perspective: Organizational principles of membranes below 100 nm — Experimental breakthroughs occasion a modeling manifesto” Biophys. J. 115:595-604(2018) 

Ashkar, et al. “Progress and prospects for neutron scattering in the biological sciences” Acta Cryst. D 74:1129(2018) 

2017

Rouviere, E; Arnarez, C.; Yang, L.; Lyman, E. “Identification of two new cholesterol interaction sites on the A2A adenosine receptor” Biophys. J. 113: 2415(2017) 

2016

A. J. Sodt, Venable, R. M., Lyman, E., and Pastor, R. W., “Nonadditive Compositional Curvature Energetics of Lipid Bilayers”, Phys. Rev. Lett., vol. 117, p. 138104, 2016.

Sodt, A and Lyman, E “New and Notable: Amphipathic helices — Wedge? Or Nae Nae?” Biophys. J. 110:1-2 (2016) 

Zgorski, A. and Lyman, E. “Toward hydrodynamics with solvent-free lipid models: STRD Martini,” Biophys. J. 111:2689(2016) 

2015

E. Lyman, “Retinal Flips the Script.”, Biophysical journal, vol. 108, no. 12, p. 2754, 2015.

Sodt, A; Pastor, R.; Lyman, E. “Hexagonal substructure and hydrogen bonding in liquid ordered phases containing palmitoyl sphingomyelin” Biophys. J. (cover article) 109:948-955 (2015) 

2014

Sodt, A.; Sandar, M. L.; Gawrisch, K.; Pastor, R.; Lyman, E. “The Molecular Structure of the Liquid Ordered Phase of Lipid Bilayers” J. Am. Chem. Soc. 136: 725-732 (2014) DOI: 10.1021/ja4105667 

2013

H. Cui, Mim, C., Vazquez, F. X., Lyman, E., Unger, V. M., and Voth, G. A., “Understanding the Role of Amphipathic Helices in N-BAR Domain Driven Membrane Remodeling”, Biophysical journal, vol. 104, pp. 404-411, 2013.

Lee, J.Y.; Patel, R.; Lyman, E. “Ligand-dependent cholesterol interactions with the human A2A adenosine receptor” Chem. Phys. Lipids 169: 39-45(2013) 

2012

J. Y. Lee and Lyman, E., “Agonist Dynamics and Conformational Selection during Microsecond Simulations of the A2A Adenosine Receptor”, Biophysical journal, vol. 102, pp. 2114-2120, 2012.

C. - L. Lai, Jao, C. C., Lyman, E., Gallop, J. L., Peter, B. J., McMahon, H. T., Langen, R., and Voth, G. A., “Membrane Binding and Self-Association of the Epsin N-Terminal Homology Domain”, Journal of Molecular Biology, vol. 423, pp. 800-817, 2012.

J. Y. Lee and Lyman, E., “Predictions for Cholesterol Interaction Sites on the A2A Adenosine Receptor”, J. Am. Chem. Soc., vol. 134, pp. 16512-16515, 2012.

C. Mim, Cui, H., Gawronski-Salerno, J. A., Frost, A., Lyman, E., Voth, G. A., and Unger, V. M., “Structural Basis of Membrane Bending by the N-BAR Protein Endophilin”, Cell, vol. 149, pp. 137-145, 2012.

2011

H. Cui, Lyman, E., and Voth, G. A., “Mechanism of Membrane Curvature Sensing by Amphipathic Helix Containing Proteins”, Biophys. J., vol. 100, pp. 1271-1279, 2011.

E. Lyman, Cui, H., and Voth, G. A., “Reconstructing protein remodeled membranes in molecular detail from mesoscopic models”, Physical Chemistry Chemical Physics, vol. 13, pp. 10430-10436, 2011.