Abstract
Abstract
There is a need for preventing intervertebral disc herniations following discectomy, especially in the lumbar region of the spine. A proof of concept biomedical device was developed, composed of a polycaprolactone (PCL) plug and a titanium alloy anchor and screws. Finite element analysis with a static load of 400N demonstrated a lack of yielding for the device. Tensile testing with 100N and 200N static loads demonstrated a significant reduction in protrusion length of up to six times in an artificial L4-disc-L5 model with our device compared to the control. We concluded that our device concept fulfills the criteria for reducing post-surgical disc protrusions resulting from disc reherniation. Future considerations include the incorporation of adhesives for better sealing, modification of plug material, addition of a protrusion on the plug that fits into the herniation, incorporation of sterilization approaches, and addition of a drug eluting or releasing mechanism.
Goals
Provide proof of concept of a medical device that can:
reduce protrusion from a small herniation site
reduce the rate of re-herniation
reduce back pain