Embedded Files
Abstract
Abstract
Transposable elements (TEs) make up nearly half the human genome and play key roles in evolution, gene regulation, and genomic diversity. By comparing high-quality, gapless genomes from humans and great apes, we trace the evolutionary history of TEs across primate lineages. Using the T2T-CHM13 human reference and orthologous mapping to chimpanzee, gorilla, and orangutan genomes, we chart the temporal activity of TE insertions. Our work reveals how ancient and lineage specific TE events shape primate genomes and contribute to functional divergence.
Methods
Methods
Given the T2T-CHM13 reference genome assembly along with the 8-way alignment data and UCSC LiftOver, how did we filter our data samples and develop a age quantification range?
Discussion
Discussion
Using KRAS driven cancer data sets, we used our R script to see what type of TEs are found and the implications behind the quantifiable expression noticed
Conclusions and Acknowledgments
Conclusions and Acknowledgments
Project Future Directions and a huge shout out to the Kim lab :)
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