ME Sherlock, KE Segar, JS Kieft “A compact viral IRES translates a downstream open reading frame” bioRxiv. Preprint

KE Segar, ME Sherlock, JS Kieft “Distribution and structural diversity of Type IV internal ribosome entry sites” bioRxiv Preprint

MD Kellett, V Sharma, ME Sherlock, U Pugazhenthi, MM Rose, MU Joshi, M Dzieciatkowska, V Nguyen, P Reigan, KC Hansen, JS Kieft, RE Schweppe “Focal adhesion kinase promotes ribosome biogenesis to drive advanced thyroid cancer cell growth and survival” Frontiers in Oncology 15, 1252544. Article link.

ME Sherlock, CJ Langeberg, KE Segar, JS Kieft “A conserved class of viral RNA structures regulate translation reinitiation through dynamic ribosome interactions” Cell Reports 44, 115236

CJ Langeberg, MJ Szucs, ME Sherlock, Q Vicens, JS Kieft “Tick-borne flavivirus exoribonuclease-resistant RNAs contain a double loop structure” Nature Communications 16, 4515

ME Sherlock, CJ Langeberg, JS Kieft “Diversity and modularity of tyrosine-accepting tRNA-like structures” RNA 30, 213-222.

ME Sherlock, L Baquero Galvis, Q Vicens, JS Kieft, S Jagannathan “Principles, mechanisms, and biological implications of translation termination–reinitiation” RNA 29, 865-884. 

ME Sherlock, G Higgs, D Yu, DL Widner, NA White, N Sudarsan, H Sadeeshkumar, KR Perkins, G Mirihana-Arachchilage, SN Malkowski, CG King, KA Harris, G Gaffield, RM Atilho, RR Breaker “Architectures and complex functions of tandem riboswitches” RNA Biology 19, 1059-1076.

S Bonilla, ME Sherlock, A MacFadden, JS Kieft (2021) “A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure” Science 374, 955-960.

CJ Langeberg, ME Sherlock, A MacFadden, JS Kieft (2021) “An expanded class of histidine-accepting viral tRNA-like structures” RNA 27, 653-664.

ME Sherlock, EW Hartwick, A MacFadden, JS Kieft (2021) “Structural diversity and phylogenetic distribution of valyl tRNA-like structures in viruses” RNA 27, 27-39.

ME Sherlock, RR Breaker "Former orphan riboswitches reveal unexplored areas of bacterial metabolism, signaling, and gene control processes" RNA 26, 675-693. 

ME Sherlock, H Sadeeshkumar, RR Breaker "Variant bacterial riboswitches associated with nucleotide hydrolase genes sense nucleoside diphosphates" Biochemistry 58, 401-410.

EB Greenlee, S Stav, RM Atilho, KI Brewer, KA Harris, SN Malkowski, G Mirihana-Arachichilage, KR Perkins, ME Sherlock, RR Breaker "Challenges of ligand identification for the second wave of orphan riboswitch candidates" RNA Biology 15, 377-390.

ME Sherlock, N Sudarsan, RR Breaker "Riboswitches for the alarmone ppGpp expand the collection of RNA-based signaling systems" Proc. Natl. Acad. Sci. USA 115, 6052-6057.

ME Sherlock, N Sudarsan, S Stav, RR Breaker “Tandem riboswitches form a natural Boolean logic gate to control purine metabolism in bacteria” eLife 7, e33908.

G Mirihana-Arachichilage, ME Sherlock, Z Weinberg, RR Breaker "SAM-VI RNAs selectively bind S-adenosylmethionine and exhibit similarities to SAM-III riboswitches" RNA Biology 15, 371-378.

Z Weinberg, CE Lünse, KA Corbino, TD Ames, JW Nelson, A Roth, KR Perkins, ME Sherlock, RR Breaker “Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions” Nucleic Acids Res. 18, 10811-10823.

PJ McCown, KA Corbino, S Stav, ME Sherlock, RR Breaker “Riboswitch diversity and distribution” RNA 23, 995-1011.

ME Sherlock, RR Breaker “Biochemical validation of a third guanidine riboswitch class in bacteria” Biochemistry 56, 359-363.

ME Sherlock, SN Malkowski, RR Breaker “Biochemical validation of a second guanidine riboswitch class in bacteria” Biochemistry 56, 352-358.

RR Breaker, RM Atilho, SN Malkowski, JW Nelson, ME Sherlock “The biology of free guanidine as revealed by riboswitches” Biochemistry 56, 345-347.

Z Weinberg, JW Nelson, CE Lünse, ME Sherlock, RR Breaker “Bioinformatic analysis of riboswitch structures uncovers variant classes with altered ligand specificity” PNAS 114, 2077-2085.

JW Nelson, RM Atilho, ME Sherlock, RB Stockbridge, RR Breaker “Metabolism of free guanidine in bacteria is regulated by a widespread riboswitch class” Mol. Cell 65, 220-230.

ME Sherlock, CA Rumble, CK Kwok, J Breffke, M Maroncelli, PC Bevilacqua “Steady-state and time-resolved studies into the origin of the intrinsic fluorescence of G-quadruplexes” J. Phys. Chem. B 120, 5146–5158.

E Martin, N Pagano, ME Sherlock, K Harms, E Meggers “Synthesis and anticancer activity of ruthenium half-sandwich complexes comprising combined metal centrochirality and planar chirality” Inorg. Chim. Acta 423, 530-539.

CK Kwok, ME Sherlock, PC Bevilacqua “Effect of loop sequence and loop length on the intrinsic fluorescence of G-quadruplexes” Biochemistry 52, 3019–3021.

CK Kwok, ME Sherlock, PC Bevilacqua "Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes" Angew. Chem. Int. Ed. 52, 683-686.

CK Kwok, Y Ding, ME Sherlock, SM Assmann, PC Bevilacqua "A hybridization-based approach for quantitative and low-bias single-stranded DNA ligation" Anal. Biochem. 435, 181-186.