We're excited to share that our News & Notes site now features a Publication Highlights section, showcasing recent articles published by members of our department. This section will be updated monthly to share ongoing research across our department.
Please note that not every article will automatically be captured, as the information is pulled from a single database. If you don't see your publication listed and would like it to be featured, please email the details to pedsr@ualberta.ca
We are excited to announce the launch of our Faculty Researchers page on the Department of Pediatrics website! This dynamic new feature highlights our department's cutting edge research and incredible talent, providing a hub for collaboration and inspiration. If you're a faculty researcher in our department and would like to showcase your work, we'd love to hear from you! Just email pedsr@ualberta.ca for more details!
With rates of inflammatory bowel diseases — or IBD — on the rise in Canadian children, the search for effective treatments has become increasingly urgent.
For her postdoctoral fellowship with the Women and Children’s Health Research Institute (WCHRI), Anissa Armet is working on two clinical trials to look at the potential for health professionals to create customized diets for children with IBD based on their gut microbiome, to reduce inflammation and improve their health.
She recently co-led an international, multi-disciplinary study involving researchers from the U of A that showed it is possible to restore damage to the gut microbiome caused by industrialized diets, with one that mimics what non-industrialized populations, including people indigenous to rural Papua New Guinea, eat regularly.
Anissa is supervised by pediatrics professors Eytan Wine and Justine Turner.
With childhood obesity rates on the rise, researchers are urgently investigating the safety of the popular weight-loss drug semaglutide, marketed as Ozempic. For his postdoctoral fellowship with the Women and Children’s Health Research Institute (WCHRI), Yasser Abuetabh’s focus is on the drug’s long-term impact on children’s hearts.
Semaglutide has shown promise in treating obesity and Type 2 diabetes in adults. It mimics a hormone released from the gut, promoting feelings of fullness and improving blood sugar control. Yet, findings from a recent study by Abuetabh and Jason Dyck, a pediatrics professor and director of the Cardiovascular Research Centre, have illuminated a potential concern: the drug appears to lead to smaller heart sizes in obese adult mice.
Autism researcher Lonnie Zwaigenbaum and a national team of scholars developed two studies to investigate novel detection and intervention strategies in high-risk toddlers as young as six months. As part of a Canadian Paediatric Society task force, the pediatrics professor and department director of autism research contributed to three national practice guidelines on early ASD detection, assessment and management.
Department of Pediatrics member Dr. Lillian Lim recently published an article in the Journal of Pediatrics that provides a medical progress update on the advances in chronic nonbacterial osteomyelitis (CNO). It is intended for general pediatricians and pediatric specialists.
Dr. Geoff Ball, professor of Pediatrics and co-chair of the panel of more than 50 experts, helped lead the development of Canada's updated pediatric obesity guidelines—the first in nearly 20 years. The new guidelines expand treatment options to include medication and surgery, emphasizing a personalized, evidence-based approach that values physical and mental health outcomes.
Pediatrics professor Justine Turner was involved in a new study that indicated that almost half of Canadian households with children with celiac disease struggle to afford gluten-free foods. Of the more than 650 survey respondents, 47 per cent reported experiencing food insecurity, and of those, more than 30 per cent grappled with low to very low accessibility.
Presenting our Presence vodcast chatted with Grant Bruno about his work in the Department of Pediatrics on finding supports for Indigenous children with autism.
A pilot study involving pediatrics professor Susan Gilmour shows that resistance training in young liver transplant patients can help preserve muscle and alleviate adverse outcomes associated with sarcopenia, a type of muscle loss prevalent in transplant patients due to the immunosuppressive medications they must take. Read more.
Dr. Rasmussen and her team are researching ways to improve the math skills of children with learning difficulties through the MILE program. MILE is an evidence-based intervention to support math learning by targeting underlying cognitive skills involved in math while also building self-regulation in children. Her team trained educators to administer MILE classroom-wide for children with various learning needs. So far, MILE has been implemented in 19 classrooms across Alberta, impacting an estimated 600-700 students, and MILE is now being implemented in Manitoba. After completing the MILE program, students experienced significant increases in math achievement, and teachers reported increased self-efficacy. Her team is currently developing a MILE training website to allow educators to access MILE from anywhere and to enable MILE to impact more children.
Not just educational research and work! Dr. Karen Forbes & Dr. Jess Foulds are active participants in the Paediatric Inpatient Research Network (PIRN), a Canadian network developed to generate evidence that improves care and outcomes for hospitalized children in general pediatric settings. They have numerous trainees who have been involved in the Trainee Research Advisory Committee, including Dr. Katharine Jensen, Dr. Claudia Maki, and Dr. Manisha Bharadia, to name a few. Dr. Forbes is a member of the Executive Committee as Education Lead. Dr. Foulds is Mentorship Lead on the PIRN Executive, and site lead for two active multi-site projects, one CIHR-funded prospective study looking at the role of renal ultrasound in first presentation febrile UTIs (the ROUTINE study), and one retrospective multi-site trial looking at the use of high-flow nasal cannula in bronchiolitis and predictors of failure of HFNC.
You can click here for a complete list of ongoing projects with PIRN.
If you have any questions about PIRN or want to chat about evidence for and care of hospitalized pediatric patients, don't hesitate to reach out! And if medical education is your jam, they’re all ears for that too!
Dr. Samina Ali along with others with the Department of Pediatrics, members of WCHRI and PEAK, have been exploring children's experiences and needs when attending Canadian pediatric emergency departments through the development of a national survey. Optimizing a child's emergency department (ED) experience positively impacts their memories and future healthcare interactions. Their objectives were to describe children's perspectives of their needs and experiences during their ED visit and relate this to their understanding of their condition.
This work was supported by the Women and Children’s Health Research Institute via both a Clinical/Community Research Integration Support Program grant and through a generous donation from the Stollery Children's Hospital Foundation
The PICUs in Canada have been analyzing the impact of restricting family presence in the ICU during the COVID-19 pandemic. The Stollery PICU staff participated as subjects, with Dr D Garros as a senior co-author on several papers. To date, there have been 4 publications describing the impact of such restrictive measures on administrators, Clinicians and families. Two Qualitative papers analyzed the clinicians' experiences and, most importantly, the families' experiences. The responses from Canadian families are particularly poignant, describing the profound impact of being alone at the bedside, even facing deprivation of basic necessities. A study on the impact on children and teenagers is coming soon. The reason for delving into these papers, despite COVID-19 being an extraordinary and devastating event, is to heed the lessons learned about the critical importance of family presence and to use this knowledge to prevent repeating past mistakes in the future.
Check out the publications:
DOI: 10.9778/cmajo.20210202, DOI: 10.1007/s12630-023-02547-7, DOI: 10.1007/s12630-024-02742-0 & DOI: 10.1097/CCE.0000000000000989.
Patricia Candelaria and Dr. Samina Ali are researching ways to lessen children’s fear in pediatric emergency department waiting rooms using a humanoid robot in their MEDi-Kids study. Patricia Candelaria, RN and Program Manager of the Pediatric Emergency: Advancing Knowledge (PEAK) Research Team at the University of Alberta, is currently leading the MEDi-Kids study under the mentorship of Dr. Samina Ali, Professor of Pediatrics and Pediatric Emergency Medicine Research Director for the DoP. Together with Dr. Summer Hudson, general pediatrics resident, they have programmed a humanoid robot to deliver brief, psychology-based interventions and distraction, to improve children’s experiences in the ED waiting room. The robot will distract children with music and dance and engage the child in guided relaxation techniques. This project is generously funded by the ARNET Research Grant and the Salloum Foundation. Recruitment for this study launched April 2024 and is expected to be completed by Fall 2024.
Dr. Amanda Newton and others researchers are assessing how effective the JoyPop app works as a resource for Indigenous adolescents who are on the waiting list for mental health services. Should findings show that utilizing the JoyPop app is helpful, there may be support from partners and other organizations to incorporate it into usual care pathways.
Dr. Karina Top Professor of Pediatrics was featured in Folio announcing funding she and colleagues at the International Network of Special Immunization Services (INSIS) received from the Coalition for Epidemic Preparedness Innovations to support their research into biological mechanisms and risk factors for very rare adverse events following immunization, such as myocarditis and pericarditis after COVID-19 vaccination.
Pediatric emergency physician Bruce Wright is helping parents remember hospital discharge instructions. His study, supported by WCHRI, explores the communication needs of parents of children with mental health concerns admitted to the emergency department.
Dr. Conradi, and Dr. Mian (amongst many others from our Pediatrics Department) are exploring how Solar-powered O2 delivery for children with hypoxaemia can overcome gaps in O2 access in low-income and middle-income countries. Their research focuses on the benefits of installing these O2 systems in rural Ugandan hospitals on the pediatrics ward.
Grant Bruno, a pediatrics PhD student supervised by Lonnie Zwaigenbaum, is redefining autism from a Nehiyaw lens and building strengths through culture.
Pediatric cardiologist Michael Khoury plays a critical role in early intervention and preventative measures through his research to improve the heart health of young patients. Much of his research focuses on improving the fitness and physical activity levels of children with heart disease or those who develop it early in life, including children who have needed heart transplants.
Want your research to be featured? Please submit a brief summary (~100 words) along with any relevant images or links. Submissions can be sent directly to the DoP Office of Research at pedsr@ualberta.ca.