Publications

2022

21. “Inhibition of ACE2-Spike interaction by an ACE2 binder suppresses SARS-CoV-2 entry.” Shin, YH; Jeong, K; Lee, J; Lee, HJ; Kim, J; Kim, S; Park, SB, Angewandte Chemie International Edition, 2022, 61, e202115695.

20. “Exploration of α/β/γ-Peptidomimetics Design for BH3 Helical Domains.” Shin, YH^†; Yang, H, Chemical Communications, 2022, 58, 945-948. (cover)

~ 2021

19. “Phenotypic Discovery of Neuroprotective Agents by Regulation of Tau Proteostasis via Stress-Responsive Activation of PERK Signaling.” Shin, YH; Cho, H; Choi, BY; Kim, JH; Ha, JY; Suh, SW; Park, SB, Angewandte Chemie International Edition, 2021, 60, 1831-1838.

18. “Medium Effect on the α-effect for Nucleophilic Substitution Reactions of p-Nitrophenyl Acetate with Benzohydroxamates and m-Chlorophenoxide in DMSO–H₂O Mixtures as Contrasts with MeCN–H₂O Mixtures: Comparing Two Very Different Polar Aprotic Solvent Components.” Um, IH; Moon, HJ; Shin, YH; Dust, JM, Canadian Journal of Chemistry, 2018, 96, 922.

17. “Phenotype-Based High-Content Screening Using Fluorescent Chemical Bioprobes: Lipid Droplets and Glucose Uptake Quantification in Live Cells.” Shin, YH; Park, SB, Methods in Molecular Biology, 2018, 1787, 223.

16. “Impact of Backbone Pattern and Residue Substitution on Helicity in α/β/γ-Peptides.” Shin, YH; Gellman, SH, Journal of the American Chemical Society, 2018, 140, 1394-1400.

15. “Kinetic Study on Alkaline Hydrolysis of 2-Pyridyl and 4-Pyridyl X-SubstiEtuted-Benzoates: Effects of Benzoyl Substituent X and Leaving-Group Basicity on Reactivity and Reaction Mechanism.” Shin, YH; Koh, HJ; Um, IH, Bulletin of the Korean Chemical Society, 2017, 38, 1138.

14. “Multiparameter Kinetic Analysis of Alkaline Hydrolysis of a Series of Aryl Diphenyl-phosphinothioates: Models for P=S Neurotoxins.” Um, IH; Han, JY; Shin, YH; Dust, JM, Journal of Physical Organic Chemistry 2017, 30, e3657.

13. “Alkaline Hydrolysis of 4-Nitrophenyl X-Substituted-Benzoates Revisited: New Insights from Yukawa-Tsuno Equation.” Shin, YH; Kang, JS; Um, IH, Bulletin of the Korean Chemical Society, 2016, 37, 2062.

12. “Readily Accessible and Predictable Naphthalene-Based Two-Photon Fluorophore with Full Visible-Color Coverage.” Koo, JY; Heo, CH; Shin, YH; Kim, D; Lim, CS; Cho, BR; Kim, HM; Park, SB, Chemistry - A European Journal, 2016, 22, 14166.

11. “Diverse Display of Non-covalent Interacting Elements using Pyrimidine-Embedded Polyheterocycles.” Choi, Y; Kim, H; Shin, YH; Park, SB, Chemical Communications, 2015, 51, 13040.

10. “Differential Impact of β and γ Residue Preorganization on α/β/γ-Peptide Helix Stability in Water.” Shin, YH; Mortenson, DE; Satyshur, KA; Forest, KT; Gellman, SH, Journal of the American Chemical Society, 2013, 135, 8149.

9. “A Kinetic Study on Nucleophilic Displacement Reactions of Aryl Benzenesulfonates with Potassium Ethoxide: Role of K⁺ Ion and Reaction Mechanism Deduced from Analyses of LFERs and Activation Parameters.” Um, IH; Kang, JS; Shin, YH; Buncel, E, Journal of Organic Chemistry, 2013, 78, 490.

8. “Alkali-Metal-Ion Catalysis and Inhibition in the Nucleophilic Displacement Reaction of Y-Substituted Phenyl Diphenylphosphinates and Diphenylphosphinothioates with Alkali-Metal Ethoxides: Effect of Changing the Electrophilic Center from P=O to P=S.” Um, IH; Shin, YH; Park, JE; Kang, JS; Buncel, E, Chemistry - A European Journal, 2012, 18, 961.

7. “Aminolysis of X-Substituted Phenyl Diphenylphosphinates: Effect of Amine Nature on Reactivity and Transition-State Structure.” Um, IH; Han, JY; Shin, YH, Journal of Organic Chemistry, 2009, 74, 3073.

6. “Reaction Mechanism and Structure of Transition State Determined from Analysis of Brønsted β_nuc for Aminolysis of 4-Nitrophenyl Diphenylphosphinate.” Shin, YH; Kim, EH; Um, IH, Bulletin of the Korean Chemical Society, 2008, 29, 2509.

5. “Alkali Metal Ion Catalysis and Inhibition in Nucleophilic Displacement Reactions at Phosphorus Centers: Ethyl and Methyl Paraoxon and Ethyl and Methyl Parathion.” Um, IH; Shin, YH; Lee, SE; Yang, K; Buncel, E, Journal of Organic Chemistry, 2008, 73, 923.

4. “Combined Dual Substituent Constant and Activation Parameter Analysis Assigns a Concerted Mechanism to Alkaline Ethanolysis at Phosphorus of Y-substituted Phenyl Diphenylphosphinates.” Um, IH; Park, JE; Shin, YH, Organic & Biomolecular Chemistry, 2007, 5, 3539.

3. “Aminolyses of Aryl Diphenylphosphinates and Diphenylphosphinothioates: Effect of Modification of Electrophilic Center from P=O to P=S.” Um, IH; Akhtar, K; Shin, YH; Han, JY, Journal of Organic Chemistry, 2007, 72, 3823.

2. “Medium Effects on The α-effect in DMSO-H­­₂O Mixtures: Comparative Studies of p-Nitrophenyl Benzoate and Acetate. Dissection of Ground-State and Transition-State.” Um, IH; Shin, YH; Han, JY; Buncel, E, Canadian Journal of Chemistry, 2006, 84, 1550.

1. “Aminolysis of Y-Substituted Phenyl Diphenylphosphinates and Benzoates: Effect of Modification of Electrophilic Center from C=O to P=O.” Um, IH; Shin, YH; Han, JY; Mishima, M, Journal of Organic Chemistry, 2006, 71, 7715.