We investigate the cellular and molecular mechanisms underlying central nervous system injury and neurodegeneration to guide the design of advanced biomaterials. By modulating the local microenvironment at sites of injury or degeneration, we aim to develop therapeutic materials that promote neural regeneration, tissue repair, and functional recovery of the central nervous system.

Inspired by biomimicry, we develop novel zwitterionic materials with properties beyond those of conventional zwitterions. We investigate how their unique molecular structures influence physicochemical and biological interactions, and translate these properties into multifunctional polymer coatings, hydrogels, bioinks, and other biomaterial platforms. These materials are designed for applications ranging from fundamental cell biology studies to translational and clinical biomedical technologies.

From wearable devices to brain–computer interfaces, achieving stable and long-term integration between biological tissues and electronic devices remains a major challenge and an important direction for future biomedical technologies. Conductive polymers offer exceptional potential to bridge this interface by combining electrical functionality with mechanical and biological compatibility. Our laboratory is particularly interested in exploring these materials and developing advanced conductive polymer systems for next-generation bioelectronic and neural interface applications.