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The Role of RhoB in the Invasion of Human Breast Cancer Cells
The Role of RhoB in the Invasion of Human Breast Cancer Cells
Mentor: Dr. Sandra Pagano
Mentor: Dr. Sandra Pagano
Hodgson Lab - Albert Einstein College of Medicine
Hodgson Lab - Albert Einstein College of Medicine
Project Overview: Over the summer, I carried out the methodology of my proposed project. This study tested whether removing the RhoB protein from human breast cancer cells would reduce invasion and metastasis. Using western blot and Boyden chamber assays, we found that cells lacking RhoB (siRhoB-treated) migrated significantly less than control cells, confirming RhoB’s role in cell invasion. These results suggest that targeting RhoB could help develop treatments to prevent breast cancer metastasis.
A photo of the lab.
Me at the lab!
Western blot!
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