Publications

70. A. Mondal, N. Pareek, A. R. Khan, S. K. Sahoo, A. Samanta*, S. Dutta*, “A bright, water-soluble far-red fluorescent probe for detecting thiols in both mitochondria and lysosomes in living cells,” Analyst, 150(18), 4155–4168 (2025) Article Link

69. V. K. Deb, R. Yadav, A. Samanta, K. Kumar, U. Jain, “In-Vitro Anti-cancer Therapeutic Effects of 2D-Ti₃C₂-MXene-Coated Hesperetin (Ti₃C₂_H) against Cervical Cancer Cells,” Journal of Inorganic and Organometallic Polymers and Materials, 35, 1–17 (2025) Article Link 

68. A.R. Khan, N. Pareek, Mondal, A. Samanta, S. Dutta * A Dual‐Emission Probe for Discriminating Cys/Hcy from GSH/H2S in Human Blood Serum and Live Cells. Chemistry Select, 10(24) (2025) Article Link

67. T. Prabakar, P. Ambastha, R. Yadav, A. Samanta, M. Kumar Ravva, P. Munshi*, S. Sen*. Oxidative Rearrangement of 3‐Aryl Azo Indoles in Water: Synthesis of C3‐Oxo‐C2‐Amino Indoles and their Application as Fluorophores for Lipid Droplet Detection," Advanced Synthesis & Catalysis. 367(14) (2025) Article Link.

66.  S. Baskar, R. Yadav, G. Shanmugam, K. Sar+kar, A. Samanta, G. K. Kole*, "Effect of N-quaternization on crystal and electronic structures of E-pyridylvinyl benzothiazoles – Photophysical and electrochemical properties, and cytotoxicity studies," J. Photochem. Photobiol. A- Chem., 466, 116392 (2025).  Article Link. 

65. M. M. Zafar, R. Yadav, A. Singh, N. Tyagi, A. Samanta*, R. K. Mishra*, "Tetrasubstituted imidazole-based multifunctional fluorophores: trace water detection and lipid droplets (LDs) imaging studies," Chem. Commun., (2025). [In press] [DOI: 10.1039/D4CC06435F],  Article Link.

64. N. Pareek, N. Kalita, R. Pandey, A. Samanta*, "Methionine‐Derived Fluorescent Probes Targeting Mitochondria: A Tool for Real‐Time Oxidative Stress Monitoring in Live Cells," ChemBiochem, 26, e202400893 (2025).  Article Link.

63. R. Goyal, S. N. Mahapatra, R. Yadav, S. Mitra, A. Samanta, A. Kumar, B. Lochab, "3D printed cellulose nanofiber-reinforced and iron-crosslinked double network hydrogel composites: Mechanical properties and cellular viability," Bioprinting, 46, e00392 (2025). Article Link.

62. N. Pareek, R. Yadav, S. Munan, M. Baruah, A. Samanta*, "A Fluorescent Probe Differentiates Apoptosis from Cysteine‐Deprivation Ferroptosis through Imaging of Viscosity and Lipid Droplets," Chem. Eur. J., 31, e202404523 (2025).  Article Link.

61. R. Yadav, R. SanuKhan, N. Kalita, S. Mendiratta, S. Sivaramakrishnan, S. Murugan, A. Samanta*, "Molecular Imaging of Nitric Oxide Surrogates with Organelle‐Specific Fluorescent Probes," Chem. Asian J., 20, e202401237 (2025). Article Link.

60. K. Bhardwaj, R. Yadav, A. Samanta*, R. Jangir, B. R. Jali, S. A. Kumar, S. K. Sahoo, "Pyrene-Based Schiff Base for Cascade Fluorescent 'On‐Off' Detection of Aluminium (III) and Fluoride Ions and its Applications in Live Cells Imaging," Chemistry & Biodiversity, e202401790 (2024).  Article Link.

59. T. S. Kannan, R. Yadav, M. R. Sarma, G. Pramanik, A. Samanta*, G. K. Kole, "9-Phenanthrenylvinyl-4′-pyridine and Its N-Methylated Analogue: From the Crystal Structure and Photoisomerization to Photophysical and Electrochemical Properties and Application in Bioimaging," Cryst. Growth Des., 24, 7235–7245 (2024).  Article Link.

58. A. Mondal, S. Munan, I. Saxena, S. Mukherjee, P. Upadhyay, N. Gupta, W. Dar, A. Samanta, S. Singh, S. Pati, "G6PD deficiency mediated impairment of iNOS and lysosomal acidification affecting phagocytotic clearance in microglia in response to SARS-CoV-2," Biochim. Biophys. Acta (BBA)-Molecular Basis of Disease, 1870, 167444 (2024).  Article Link.

57. T. S. Kannan, S. Munan, A. Samanta*, G. K. Kole, "Quinoline-Based Viologen as a Multifunctional Organic Material – From Crystal Structures to Photophysical and Electrochemical Properties, and Application in DNA Sensing and Bioimaging," J. Photochem. Photobiol. A- Chem., 454, 115735 (2024).  Article Link.

56. S. Munan, A. Mondal, S. Singh, S. Pati, A. Samanta*, "Unique Synthetic Strategy for Probing in Situ Lysosomal NO for Screening Neuroinflammatory Phenotypes against SARS-CoV-2 RNA in Phagocytotic Microglia," Anal. Chem., 96, 7479–7486 (2024).  Article Link.

55. W. Liang, Y. Bian, A. Samanta, X. Chen, X. Yu, Y. Zheng, X. Gao, D. Su, "A simple yet effective H2S-activated fluorogenic probe for precise imaging of hepatitis and arthritis in situ," Biomed. Eng. Mat., e12086 (2024).  Article Link.

54. N. Pareek, S. Mendiratta, N. Kalita, S. Sivaramakrishnan, R. Sanu Khan, A. Samanta*, "Unraveling Ferroptosis Mechanisms: Tracking Cellular Viscosity with Small Molecular Fluorescent Probes," Chem. Asian J., e202400056, 1-13 (2024).  Article Link.

53. S. Munan, Y. T. Chang, A. Samanta*, "Chronological Development of Functional Fluorophores for Bio-Imaging," Chem. Commun., 60, 501 (2023).  Article Link.

52. S. Biswas, M. Baruah, A. Shil, S. Sarkar*, M. Ali, A. Samanta*, S. Bhuniya*, "Polarity-Driven Two-Photon Fluorescent Probe for Monitoring the Perturbation in Lipid Droplet Levels during Mitochondrial Dysfunction and Acute Pancreatitis," ACS Sens., 8, 3793-3803 (2023).  Article Link.

51. T. S. Kannan, S. Munan, M. Khatiresan, A. Samanta, G. K. Kole, "Solid-State Photodimerization Reaction with Photosalient Effect and Photophysical and Electrochemical Properties of N-Methylated 1-Naphthylvinyl-4-Quinoline," Cryst. Growth Des., 23, 8261-8269 (2023).  Article Link.

50. S. Rath, D. Maiti, M. Modi, P. Pal, S. Munan, B. Mohanty, A. Bhatia, R. Bhowal, R. Priyadarshini, A. Samanta, P. Munshi,* S. Sen.* Metal-free synthesis and study of glycine betaine derivatives in water for antimicrobial and anticancer applications, iScience 26, 107285 (2023),  Article Link.

49. S. Munan, R. Yadav, A. Samanta.* Ratiometric fluorescent probes for pH mapping in cellular organelles, Analyst 148, 4242-4262 (2023),  Article Link.

48. M. Baruah, A. Jana, N. Pareek, S. Singh, A. Samanta.* A Ratiometric Fluorescent Probe for Hypochlorite and Lipid Droplets to Monitor Oxidative Stress, Biosensors 17, 662 (2023),  Article Link.

47. R. Yadav, S. Munan, M. Ali, K. Mapa, A. Samanta.*  A Systematic Design and Synthesis of PET-based Fluorescent Probes for Monitoring pH During Mitophagy, Chem. Asian J. 18, e202300308 (2023),  Article Link.

46. R. Yadav, S. Munan, V. Kardam, K. D. Dubey, A. Samanta.*, Esterase Specific Fluorescent Probe: Mechanistic Understanding Using QM/MM Calculation and Cell States Discrimination, Chem. Eur. J. 7, e202300244 (2023),  Article Link.

45. M. Baruah, H. W. Kwon, H. Cho, Y. T. Chang, A. Samanta.* A Photoinduced Electron Transfer-Based Hypochlorite-Specific Fluorescent Probe for Selective Imaging of Proinflammatory M1 in a Rheumatoid Arthritis Model, Anal. Chem. 95, 4147-4154 (2023),  Article Link.

44. D. Maiti, S. Munan, S. Singh, R. Das, A. Samanta.*, S. Sen.* Light induced diversity-oriented synthesis (DOS) library of annulated indolizine fluorophores for imaging non-lysosomal lipid droplets (LDs), J. Mater. Chem. B 11, 2191-2199 (2023),  Article Link.

43. D. Bera, M. Baruah, A. Dehury, A. Samanta, Y. Chaudhary, N. Goswami.*
Depletion Driven Assembly of Ultra-Small Metal Nanoclusters: From Kinetically Arrested Assemblies to Thermodynamically Stable, Spherical Superclusters, J. Phys. Chem. Lett. 40, 9411–9421 (2022),  Article Link.

42.  S. Munan, M. Ali, R. Yadav, K. Mapa*, A. Samanta.*  PET- and ICT-Based Ratiometric Probe: An Unusual Phenomenon of Morpholine-Conjugated Fluorophore for Mitochondrial pH Mapping during Mitophagy, Anal. Chem. 94, 11633–11642 (2022),  Article Link.

41. M. Baruah, A. Jana, M. Ali, K. Mapa, A. Samanta.* An efficient PeT-based fluorescent probe for mapping mitochondrial oxidative stress produced via the Nox2 pathway, J. Mater. Chem. B 10, 2230-2237 (2022),  Article Link.

40. A. Jana, M. Baruah, A. Samanta.*Activity-based fluorescent probes for sensing and imaging of Reactive Carbonyl species (RCSs), Chem. Asian J. 14, e202200044. (2022),  Article Link.

39. S. Munan, S. Kottarathil, M. M. Joseph, A. Jana, M. Ali, K. Mapa, K. Kumar Maiti, A. Samanta.* IndiFluors: A New Full-Visible Color-Tunable Donor–Acceptor–Donor (D1–A–D2) Fluorophore Family for Ratiometric pH Imaging during Mitophagy,  ACS Sens. 9, 7, 3502–3510, (2024),  Article Link.

38. A. N. Ramya, M. M. Joseph, V. Karunakaran, C. V. S. Ahammed, A. Samanta, K. K. Maiti.* An Efficient Molecular Luminophore based on Tetraphenylethylene (TPE) Enabling intracellular Detection and Therapeutic Benefits of Hydrogen Sulfide in Alzheimer’s Disease, Sens. Actuators B Chem. 355, 131118 (2022),  Article Link.

37. A. Jana, M. M. Baruah, S. Munan, A. Samanta.* ICT-based water-soluble fluorescent probe for discriminating mono and dicarbonyl species and analysis in foods, Chem. Commun. 57, 6380-6383 (2021),  Article Link.

36. A. Jana, M. M. Joseph, S. Munan, S. K. Shamna, K. K. Maiti, A. Samanta.* A single benzene fluorescent probe for efficient formaldehyde sensing in living cells using glutathione as an amplifier, J. Photochem. Photobiol. B 214, 112091 (2021),  Article Link.

35. A. Jana, M. M. Joseph, S. Munan, K. K. Maiti, A. Samanta.* Highly selective chemosensor for reactive carbonyl species based on simple 1,8-diaminonaphthalene, J. Photochem. Photobiol. B 213, 112076 (2020),  Article Link.

34. S. Chakraborty, M. M. Joseph, S. Varughese, S. Ghosh, K. K. Maiti, A. Samanta.*, A. Ajayaghosh. A new pentacyclic pyrylium fluorescent probe that responds to pH imbalance during apoptosis, Chem. Sci. 11, 12695-12700 (2020),  Article Link.

33. Kim, J. J., Lee, Y.A., Su, D., Lee, J., Park, S. J., Kim, B., Lee, J. H. J., Hong, S. C., Lu, W., Samanta A., Kwon, H.Y., Kim, J.Y., Wang, Z., Kang, N.Y., Chang Y.T.* A Novel NIR Probe Tracks and treats Lung Tumor Initiating Cells by targeting HMOX2, J. Am. Chem. Soc. 141, 14673-14686 (2019).

32. Park, S. J., Ho, H. C., Arai, S., Samanta A., Olivo, M., Chang Y. T.,* Visualizing Alzheimer's Disease Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7, Sci. Report 9, 12052 (2019).

31. Sudheesh, K. V., Jayaram, P.S., Samanta A., Bejoymohandas, K. S., Jayashree, R. S., Ajayaghosh, A.* A Cyclometalated Ir(III) Complex as Lysosome Targeted Photodynamic Therapeutic Agent for Integrated Imaging and Therapy in Cancer Cells, Chem. Eur. J. 24, 10999-11007 (2018).

30. Sudheesh, K. V., Joseph, M. M., Philips, D. P., Samanta A., Maiti, K. K., Ajayaghosh, A.* pH‐Controlled Nanoparticles Formation and Tracking of Lysosomal Zinc Ions in Cancer Cells by Fluorescent Carbazole–Bipyridine Conjugates, Chem. Select 3, 2416-2422 (2018).

29. Su, D., Chai L. T., Park, S. J., Kim, J. J., Samanta A., Bi, R., Dinish, U.S., Olivo, M., Chang, Y. T. Seeing Elastin: A Near-Infrared Zwitterionic Fluorescent Probe for In Vivo Elastin Imaging, Chem 4, 1128-1138 (2018).

28. Peng, J.; Samanta A. ; Zeng, X.; Han, S.; Wang, L.; Su, D.; Loong, D. T. B.; Kang, N. Y.; Park, S. J.; All, A. H.; Jian, W.; Yuan, L.; Liu, X.; Chang, Y. T. (joint 1st Author) Real-Time In Vivo Hepatotoxicity Monitoring Through Chromophore-Conjugated Photon-Upconverting Nanoprobes, Angew. Chem. Int. Ed. Engl. 56, 4165–4169 (2017).

27. Han, S.; Samanta A.; Xie, X.; Huang, L.; Peng, J.; Park, S. J.; Teh, D. B. L.; Choi, Y.; Tian, J.; Chang, Y. T.; All, A. H.; Yang, Y.; Xing, B.; Liu, X. Gold and Hairpin DNA Functionalization of Upconversion Nanocrystals for Imaging and In Vivo Drug Delivery, Adv. Mater. 29, 1700244 (2017).

26. Kang, H.; Jeong, S.; Jo, A.; Chang, H.; Yang, J-K.; Jeong, C.; Kyeong, S.; Lee, Y. W.; Samanta A.; Maiti, K. K.; Cha, M. G.; Kim, T.-K.; Lee, S.; Jun, B- H.; Chang, Y. T.; Chung, J.; Lee, H. Y.; Jeong, D. H.; Lee, Y. S. Ultrasensitive NIR-SERRS Probes with Multiplexed Ratiometric Quantification for In Vivo Antibody Leads Validation, Adv. Healthcare Mater. 4, 1700870 (2017).

25. Peng, J.; Teoh, C. L.; Zeng, X.; Wang, L.; Xu, W.; Samanta A.  ; Su, D.; Yuan, L.; Liu, X.; Chang, Y. T. Development of highly selective, sensitive and fast response upconversion luminescent platform for hydrogen sulfide detection, Adv. Func. Mater. 26, 191-199 (2016).

24. Ni, Y.; Lee, S.; Son, M.; Aratani, N.; Ishida, M.; Samanta A.  ; Yamada, H.; Chang, Y. T.; Furuta, H.; Kim, D.; Wu, J. A Diradical Approach towards BODIPY-Based Dyes with Intense Near-Infrared Absorption around λ = 1100 nm, Angew. Chem. Int. Ed. Engl. 55, 2815–2819 (2016).

23. Roy, R. K.; Hoppe, M. M.; Sharma, N.; Srivastava, S.; Samanta A.  ; Tan, K. T.; Yang, H.; Voon, D. C.; Pang, B.; Teh, M.; Kamiya, N. M.; Hatakeyama, M.; Chang, Y. T.; Ito, Y.; Ho, K. Y.; Tan, P.; Soong, R.; Koeffler, P. H.; Yeoh, K. G.; Jeyasekharan, A. D. CEACAM6 is upregulated by H. pylori CagA and is a biomarker for early gastric cancer, Oncotarget 7, 55290-55301 (2016).

22. Peng, J.; Xu, W.; Chai L. T.; Han, S.; Samanta A.; Er, J. C.; Wang, L.; Yuan, L.; Liu, X.; Chang, Y. T. High-efficiency In Vitro and In Vivo Detection of Zn²⁺ by Dye-assembled Upconversion Nanoparticles, J. Am. Chem. Soc. 137, 2336–2342 (2015).

21. Dongdong, S.; Chai, T.; Samanta A.; Kang, N. Y.; Park, S. J.; Chang, Y. T.* The Development of a Highly Photostable and Chemically Stable Zwitterionic Near-Infrared Dye for Imaging Applications, Chem. Commun. 51, 3989-3992 (2015).

20. Zhang, L, Er, J. C.; Li, X.; Heng, J. J.; Samanta A.; Chang, Y, T. * Lee, C-L. K. Development of a Thymidine Propeller Loops Parallel-Stranded G-Quadruplexes Fluorescent Probe by Library Approach Chem. Commun. 51, 7386-7389 (2015).

19. Jeong, Y. M; Zhai, D; Hennig, H. Samanta A., Agrawalla, B. K; Bray, M.; Ljosa, V.; Carpenter, A.; Chang, Y. T. CDy6, a Photostable Probe for Long-Term Real-Time Visualization of Mitosis and Proliferating Cells Chemistry & Biology 22, 299-307 (2015).

18. Kim, E. S.; Samanta A.; Cheng, H. S.; Ding, Z.; Han, W.; Toschi, L.; Chang, Y. T. Effect of oncogene activating mutations and kinase inhibitors on amino acid metabolism of human isogenic breast cancer cells Mol. Biosyst. 11, 3378-3386 (2015).

17. Ramya A. N.; Samanta A.; Nisha, N.; Chang, Y. T. Maiti, K. K.* (Joint 1st Author), New insight of squaraine-based biocompatible surface-enhanced Raman scattering nanotag for cancer-cell imaging Nanomedicine 10, 561-571 (2015).

16. Kang, N. Y, Park, S. J.; Ang, X. W. E.; Samanta A.; DriesseN, W. H. P.; Ntziachristos V, Vasquez, K. O. N. Peterson, J. D. Yun, S. W.; Chang, Y. T.* A macrophase uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammation Chem. Commun. 50, 6589-6591 (2014).

15. Xu, W.; Bai, J.; Peng, J.; Samanta A.; Arya, D.; Chang Y. T. Milk Quality Control: Instant and Quantitative Milk Fat Determination with a BODIPY Sensor-based Fluorescence Detector Chem. Commun. 50, 10398-10401 (2014).

14. Samanta A.; Jana, S.; Das, R.; Chang, Y. T. Wavelength and shape dependent SERS study to develop ultrasensitive nanotags for imaging of cancer cells RSC Advances 4, 12415-12421 (2014).

13. Samanta A.; Das, R.; Park, S. J.; Maiti, K. K.; Chang, Y. T.* Multiplexing SERS nanotags for the imaging of differentiated mouse embryonic stem cells (mESC) and detection of teratoma in vivo J. Nucl. Med. Mol. Imaging 4, 114-124 (2014).

12. Samanta A.; Jana, S.; Das, R. K., Chang, Y. T.* Biocompatible surface-enhanced Raman scattering nanotags for in vivo cancer detection Nanomedicine 9, 523-535 (2014).

11. Zhang, L.; Er, J. C.; Xu, W.; Qin, X.; Samanta A.; Jana, S.; Lee, C-L. K.; Chang, Y. T. “Orange alert”: A fluorescent detector for bisphenol A in water environments Anal. Chim. Acta 815, 51-56 (2014).

10. Maiti, K. K.; Dinish, U. S.; Samanta A.; Soh, K. S.; Vendrell, M.; Yun, S. W.; Olivo, M.; Chang, Y. T. Multiplex targeted in vivo cancer detection using sensitive near-infrared SERS nanotags Nano Today 7, 85-93 (2012).

9. Samanta A.; Maiti, K. K.; Soh, K. S.; Liao, X.; Vendrell, M.; Dinish, U. S.; Yun, S. W.; Bhuvaneswari, R.; Kim, H.; Rautela, S.; Chung, J.; Olivo, M.; Chang, Y. T. Ultrasensitive Near-Infrared Raman Reporters for SERS-based in vivo Cancer Detection Angew. Chem. Int. Ed. Engl. 50, 6089–6092 (2011).

8. Samanta A.; Vendrell, M.; Yun, S. W.; Guan, Z.; Xu, Q. H.; Chang, Y. T. A photostable near‐infrared protein labeling dye for in vivo imaging Chem. Asian J. 6, 1353-1356 (2011).

7. Maiti K. K.; Samanta A.; Vendrell, M.; Soh, K. S.; Olivo, M.; Chang, Y. T. Multiplex cancer cell detection by SERS nanotags with cyanine and triphenylmethine Raman reporters Chem. Commun. 47, 3514-3516 (2011).

6. Vendrell, M.; Samanta A.; Yun, S. W.; Chang, Y. T. Synthesis and characterization of a cell-permeable near-infrared fluorescent deoxyglucose analogue for cancer cell imaging Org. Biomol. Chem. 9, 4760-4762 (2011).

5. Das, R. K.; Samanta A.; Ha, H. H.; Chang, Y. T. Solid Phase Synthesis of Ultra-Photostable Cyanine NIR dye library RSC Advances 1, 573-575 (2011)

4. Das, R. K.; Samanta A.; Ghosh, K.; Zhai, D.; Xu, W.; Su, D.; Leong, C.; Chang, Y. T. Target Identification: A Challenging Step in Forward Chemical Genetics Interdiscip. Bio Central 3, 1-16 (2011).

3. Samanta A.; Vendrell, M.; Das, R.; Chang, Y. T. Development of photostable near-IR cyanine dyes Chem. Commun. 46, 7406-7408 (2010).

2. Lee, J. W.; Bork, J. T. Ha, H. H.; Samanta A.; Chang, Y. T. Novel orthogonal synthesis of tagged combinatorial trazine library via Grignard reaction Aust. J. Chem 62, 1000-1006 (2009).

1. Lee, J. S.; Kang, N. Y.; Kim, Y. K.; Samanta A.; Feng, S.; Kim, H. K.; Vendrell, M.; Park, J. H.; Chang, Y. T. Synthesis of a BODIPY Library and Its Applications to the Development of Live Cell Glucagon Imaging Probe J. Am. Chem. Soc. 131, 10077-10082 (2009).

1. N. Pareek, R. Yadav, A. Samanta.* (Chapter 9) Enhancing Biomolecule Recognition Through Cellular Imaging Using Functional Fluorophores, In book: Fluorescent Chemosensing and Bioimaging, DOI: DOI: 10.1201/9781003430070-10

2. M. Baruah, N. Kalita, N. Kalita, A. Samanta.*  (Chapter 10) Advanced Strategies in Designing Fluorescent Probes for Reactive Oxygen Species Analysis In book: Fluorescent Chemosensing and Bioimaging DOI: 10.1201/9781003430070-9

3. A. Samanta*, S. Munan, A. Jana, Y. T. Chang.* (Chapter 5) Diversity orientated fluorescence library approach: Accelerating the probe development for Biological and Environmental Applications” Wiley-VCH, 2023. Fluorescent Chemosensors Edited by Luling Wu; Adam C Sedgwick; Xiao-Peng He; Tony D James,  https://doi.org/10.1039/9781839167324-00067 

1. A lysosome specific nitric oxide probe for neuroinflammation and process of synthesis thereof, Samanta A.; Munan S., Mandol A., Pati S., Singh S., Indian Patent No.: 202311040064 dt. June 12, 2023

2. Development of Photostable Near-IR Cyanine Dyes for In Vivo Imaging – Chang. Y. –T.; Samanta. A.; Vendrell. M.; Kang, N. –Y.; Maiti, K. K.; Soh, K. S.; Dinish. U. S.; Olivo. M.; International Patent Application No: PCT/SG2011/000117.; Ref: 09227N-PCT.; Docket No. 4459.1016-000

3. Licensing Technology: A Panel of Live Fluorescent Probes for the Identification of Proliferating and Potent Human Mesenchymal Stem Cells to Zenzic Labs Pte Ltd f.k.a Brilliant Research Pte Ltd.