Our research focuses on understanding how cells communicate with their environment and with each other, with a particular emphasis on ion channels and calcium signaling. We aim to unravel the molecular mechanisms underlying neurological disorders such as epilepsy, stroke, GNB1 encephalopathy, depression, and glioblastoma, as well as cardiovascular conditions such as heart attacks.
Using advanced techniques—including patch-clamp electrophysiology, lipid bilayer membrane recording, live-cell calcium imaging, CRISPR-Cas9 gene editing, and zebrafish behavioural assays—we investigate how ion channels contribute to disease pathophysiology and explore their potential as therapeutic targets.
Current projects focus on acid-sensing ion channels, pannexins, GIRK channels, and volume-regulated anion channels, with the long-term goal of developing targeted treatments for neurological and cardiovascular diseases.