CHEM 138/238 Natural Product Biosynthesis
Covers fundamental chemical logic and enzyme mechanisms involved in biosynthesis of natural products. Discussion of major classes of natural product including polyketides, nonribosomal peptides, terpenes, alkaloids. Emphasis on biosynthetic logic used by nature to form complex molecules. Discussion of several important enzyme families in context of biosynthesis, including assembly-line megasynthases, group transferases, oxidoreductases, etc. Historical account of natural product isolation and characterization, as well as modern account of synthetic biology and genome based efforts that are used in discovery of new natural products. Includes extensive survey of scientific literature in format of presentations and discussions.
CH CM145/245 Molecular Biotechnology for Engineers
Selected topics in molecular biology that form foundation of biotechnology and biomedical industry today. Topics include recombinant DNA technology, molecular research tools, manipulation of gene expression, directed mutagenesis and protein engineering, DNA-based diagnostics and DNA microarrays, antibody and protein-based diagnostics, genomics and bioinformatics, isolation of human genes, gene therapy, and tissue engineering.
CH 104D Molecular Biotechnology Lecture: From Gene to Product
Integration of molecular and engineering techniques in modern biotechnology. Cloning of protein-coding gene into plasmid, transformation of construct into E. coli, production of gene product in bioreactor, downstream processing of bioreactor broth to purify recombinant protein, and characterization of purified protein.
CH 104DL Molecular Biotechnology Laboratory: From Gene to Product
Integration of molecular and engineering techniques in modern biotechnology. Cloning of protein-coding gene into plasmid, transformation of construct into E. coli, production of gene product in bioreactor, downstream processing of bioreactor broth to purify recombinant protein, and characterization of purified protein.
CH 125 Bioseparations and Bioprocesses
Separation strategies, unit operations, and economic factors used to design processes for isolating and purifying materials like whole cells, enzymes, food additives, or pharmaceuticals that are products of biological reactors.
CH 100 Fundamentals of Chemical and Biomolecular Engineering
Introduction to analysis and design of industrial chemical processes. Material and energy balances. Introduction to programming in MATLAB